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The map label for this gene is siaT [H]

Identifier: 73540960

GI number: 73540960

Start: 1351018

End: 1352322

Strand: Direct

Name: siaT [H]

Synonym: Reut_A1265

Alternate gene names: 73540960

Gene position: 1351018-1352322 (Clockwise)

Preceding gene: 73540959

Following gene: 73540961

Centisome position: 35.49

GC content: 65.9

Gene sequence:

>1305_bases
ATGACACTGGTCGCCATCATCCTGTTCGTGGTCTTTATCGGCCTGATGCTGCTGGGCGTGCCCATCGGCGTGTCGCTGGG
CCTTGGCGGGCTTGTCGCCATCGGCCTGTCGAACCTCGATACCCAGATGTTCGGCCTGCTGGCCGTGCCGCAGAACTTCT
ATGCCGGTCTGGCCAAGTATCCGCTGCTGGCCATTCCCATGTTCGTGCTGGTCGGATCGATCTTTGATCGCTCTGGCGTG
GCGCAGCGCCTGGTGACGTTTGCCATCGCTATCGTCGGGCGTGGCCCCGGCATGCTGCCGCTGGTCGCCATTCTGGTGGC
CATGTTTCTCGGCGGCATTTCGGGCTCTGGCCCCGCCAACGCGGCCGCCGTCGGCGGCGTGATGATCGCGGCGATGTCGC
GGGCCGGCTATCCGGGTTCGTACAGCGCGGCAGTGGTCGGCGCCGCGGCGGCGACCGACATCCTGATTCCGCCTTCGGTG
GCCTTCATCATCTACAGCGTGCTGGTGCCGGGTGCTTCGGTGCCTGCGCTGTTCGCGGCCGGCATGATCCCGGGCGTGCT
GGCCGGCGTGGCGCTGATCGTGCCGGCGGTGTGGCTGGCCCGCAAGCACAACATGGGCGCCATCGAAGCCGCGCTGCCGC
GCCCGCCGTTCTGGAAGAGCCTGCGCGAGGCAGCCTGGGGCCTGGTCGCGCCATTCCTAATTCTCGGTGGCATGCGTGCC
GGCTGGTTCACGCCAACCGAAGCCGCGGTGGTTGCGGTGGTCTATGGCCTGTTCGTGGGCATGGTGATCTACCGCAGCAT
TGGCATGAAGGACCTGTTCGTGATCTTCCAGGAGGCGGCGGAGACCTCGGCCGTGATCCTCCTGGTGGTCGCGCTGGCTG
GCATCTTCGCGTATGCGCTGTCGACGCTCGGCGTCATTGACCCGCTCGCAAACGCGATCGCCAACTCCGGTCTCGGCGAA
TACGGCGTGCTGGCGCTGATCGTGCTGCTGCTGATGACGGTTGGCATGTTCCTGGACGGCATTTCTATCTTCCTGATCTT
CGTGCCGCTGCTGCTGCCGATCGCCACCGCGTTCCACTGGAACCCGGTGTGGTTCGGGGTGGTGCTCACGCTCAAGGTGG
CGCTGGGGCAGTTCACGCCGCCGCTGGCCGTGAACCTGATGGTGTCGTGCCGGATTGCCCGCGTGCGCATGGAGGAGACC
GTGCCCTGGGTGGTCTGGATGCTGCTGGCGATGTTCATCGCCATGCTGATGGTGCTGGCCTATCCGCCGCTGGCGACGTG
GTTGCCGGACTATCTGGGCTATTGA

Upstream 100 bases:

>100_bases
CGGCCGCGATCGCGCTGCGCGCGTTCGGGCTGATGGCGCGCAACGTGCGCGCGCTCAAGGGGCTGCATGCCGCCCGCAAC
GAACAAGCGGGGCGCAAGCC

Downstream 100 bases:

>100_bases
TGCCCGCTACATACAACAAGCTGCAAGCAACGATTCCCAAGAGGAGAGACCTGATGAAACGCCGTGCCCTGATGCTGTCG
ATCGCTGCCACGATCGCCGC

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTLVAIILFVVFIGLMLLGVPIGVSLGLGGLVAIGLSNLDTQMFGLLAVPQNFYAGLAKYPLLAIPMFVLVGSIFDRSGV
AQRLVTFAIAIVGRGPGMLPLVAILVAMFLGGISGSGPANAAAVGGVMIAAMSRAGYPGSYSAAVVGAAAATDILIPPSV
AFIIYSVLVPGASVPALFAAGMIPGVLAGVALIVPAVWLARKHNMGAIEAALPRPPFWKSLREAAWGLVAPFLILGGMRA
GWFTPTEAAVVAVVYGLFVGMVIYRSIGMKDLFVIFQEAAETSAVILLVVALAGIFAYALSTLGVIDPLANAIANSGLGE
YGVLALIVLLLMTVGMFLDGISIFLIFVPLLLPIATAFHWNPVWFGVVLTLKVALGQFTPPLAVNLMVSCRIARVRMEET
VPWVVWMLLAMFIAMLMVLAYPPLATWLPDYLGY

Sequences:

>Translated_434_residues
MTLVAIILFVVFIGLMLLGVPIGVSLGLGGLVAIGLSNLDTQMFGLLAVPQNFYAGLAKYPLLAIPMFVLVGSIFDRSGV
AQRLVTFAIAIVGRGPGMLPLVAILVAMFLGGISGSGPANAAAVGGVMIAAMSRAGYPGSYSAAVVGAAAATDILIPPSV
AFIIYSVLVPGASVPALFAAGMIPGVLAGVALIVPAVWLARKHNMGAIEAALPRPPFWKSLREAAWGLVAPFLILGGMRA
GWFTPTEAAVVAVVYGLFVGMVIYRSIGMKDLFVIFQEAAETSAVILLVVALAGIFAYALSTLGVIDPLANAIANSGLGE
YGVLALIVLLLMTVGMFLDGISIFLIFVPLLLPIATAFHWNPVWFGVVLTLKVALGQFTPPLAVNLMVSCRIARVRMEET
VPWVVWMLLAMFIAMLMVLAYPPLATWLPDYLGY
>Mature_433_residues
TLVAIILFVVFIGLMLLGVPIGVSLGLGGLVAIGLSNLDTQMFGLLAVPQNFYAGLAKYPLLAIPMFVLVGSIFDRSGVA
QRLVTFAIAIVGRGPGMLPLVAILVAMFLGGISGSGPANAAAVGGVMIAAMSRAGYPGSYSAAVVGAAAATDILIPPSVA
FIIYSVLVPGASVPALFAAGMIPGVLAGVALIVPAVWLARKHNMGAIEAALPRPPFWKSLREAAWGLVAPFLILGGMRAG
WFTPTEAAVVAVVYGLFVGMVIYRSIGMKDLFVIFQEAAETSAVILLVVALAGIFAYALSTLGVIDPLANAIANSGLGEY
GVLALIVLLLMTVGMFLDGISIFLIFVPLLLPIATAFHWNPVWFGVVLTLKVALGQFTPPLAVNLMVSCRIARVRMEETV
PWVVWMLLAMFIAMLMVLAYPPLATWLPDYLGY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=393, Percent_Identity=32.0610687022901, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45387; Mature: 45256

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHCC
>Mature Secondary Structure 
TLVAIILFVVFIGLMLLGVPIGVSLGLGGLVAIGLSNLDTQMFGLLAVPQNFYAGLAKY
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
PLLAIPMFVLVGSIFDRSGVAQRLVTFAIAIVGRGPGMLPLVAILVAMFLGGISGSGPAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCH
AAAVGGVMIAAMSRAGYPGSYSAAVVGAAAATDILIPPSVAFIIYSVLVPGASVPALFAA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHH
GMIPGVLAGVALIVPAVWLARKHNMGAIEAALPRPPFWKSLREAAWGLVAPFLILGGMRA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GWFTPTEAAVVAVVYGLFVGMVIYRSIGMKDLFVIFQEAAETSAVILLVVALAGIFAYAL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLGVIDPLANAIANSGLGEYGVLALIVLLLMTVGMFLDGISIFLIFVPLLLPIATAFHW
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPVWFGVVLTLKVALGQFTPPLAVNLMVSCRIARVRMEETVPWVVWMLLAMFIAMLMVLA
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPPLATWLPDYLGY
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]