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The map label for this gene is uxuR [H]

Identifier: 73540955

GI number: 73540955

Start: 1345490

End: 1346197

Strand: Reverse

Name: uxuR [H]

Synonym: Reut_A1260

Alternate gene names: 73540955

Gene position: 1346197-1345490 (Counterclockwise)

Preceding gene: 73540957

Following gene: 73540954

Centisome position: 35.37

GC content: 70.34

Gene sequence:

>708_bases
ATGGATATCCTGCCCCGCCCGGCCTCGCTGGCCAACCGCATCGCCCAATCGCTACGCAAGGACATTGCCGCGGGCCGGTT
CGCAACCGGCGCGCGCTTGCCCGCCGAGTCAGCACTGGCCGAAACGTTTGGCGTGAGCCGCCCGATCGTGCGCGAGGCGA
TCGCTTTGCTTAAGGCGGACGGCATCCTGGTGACGCGCAAGGGCGCAGGCGCTTACGTCTCTGATACGCCAGGCGGACAA
GCGTGGCGTGTCGCCAGCGCGCCAGACGGCGGTCCGACGCTGGCCCAGCTGTTCGAGCTGCGCATGGTCGTGGAAACCGC
GTGCGCCGAAATGGCCGCGGCACGCAGGACAGAGGCGGACCTGCTGCAGATCCGCGAGGCACTGGCTGGCATGCAGGACC
AGGCCGGCGATTTCGCGGCCGCGGCTGCTGCCGATATCGCGTTTCACCACGCCATCGCCCAGGCCGCGCACAACCCGTGC
GTCACCGGGCTGACCGATTTCGTCAGCCAGCAGATGCTGGCCGCGCGCCAGCGCGCCTGGGAAAACACCGCCCGCTTGCA
GGTTCGGGACGGCGCCGCGCGGGCCGCGGATTCAGAACACGCGGCGCTGGTGGACGCGATTGCCAGCGGCAACCCGGCCA
CTGCGCGGCAGGCGGCACTCGACCACCTGAACGCCGCCGCCGGACGGCTTGGCCTTCGCCTGGTCTGA

Upstream 100 bases:

>100_bases
GCGAATTTTCAAGCGCAGGCGGTCGCCTCTTGACGATCAGGACTCCGATCGGCAAAATCCAATCGAAATCTGTCTGACAG
CCTGACATCTAAGTATCATC

Downstream 100 bases:

>100_bases
GACGGTCAGGCGCATATCGAATACAGCATCAACCAGAACAAGGGAAAGACCATGGAGAACGTCGATTGCGTGGTGATCGG
TGCAGGCGTCGTCGGGCTGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MDILPRPASLANRIAQSLRKDIAAGRFATGARLPAESALAETFGVSRPIVREAIALLKADGILVTRKGAGAYVSDTPGGQ
AWRVASAPDGGPTLAQLFELRMVVETACAEMAAARRTEADLLQIREALAGMQDQAGDFAAAAAADIAFHHAIAQAAHNPC
VTGLTDFVSQQMLAARQRAWENTARLQVRDGAARAADSEHAALVDAIASGNPATARQAALDHLNAAAGRLGLRLV

Sequences:

>Translated_235_residues
MDILPRPASLANRIAQSLRKDIAAGRFATGARLPAESALAETFGVSRPIVREAIALLKADGILVTRKGAGAYVSDTPGGQ
AWRVASAPDGGPTLAQLFELRMVVETACAEMAAARRTEADLLQIREALAGMQDQAGDFAAAAAADIAFHHAIAQAAHNPC
VTGLTDFVSQQMLAARQRAWENTARLQVRDGAARAADSEHAALVDAIASGNPATARQAALDHLNAAAGRLGLRLV
>Mature_235_residues
MDILPRPASLANRIAQSLRKDIAAGRFATGARLPAESALAETFGVSRPIVREAIALLKADGILVTRKGAGAYVSDTPGGQ
AWRVASAPDGGPTLAQLFELRMVVETACAEMAAARRTEADLLQIREALAGMQDQAGDFAAAAAADIAFHHAIAQAAHNPC
VTGLTDFVSQQMLAARQRAWENTARLQVRDGAARAADSEHAALVDAIASGNPATARQAALDHLNAAAGRLGLRLV

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=229, Percent_Identity=34.4978165938865, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786303, Length=226, Percent_Identity=33.1858407079646, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790032, Length=235, Percent_Identity=30.2127659574468, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790780, Length=155, Percent_Identity=34.1935483870968, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789353, Length=236, Percent_Identity=27.1186440677966, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082208, Length=232, Percent_Identity=28.448275862069, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789621, Length=227, Percent_Identity=29.0748898678414, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24446; Mature: 24446

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILPRPASLANRIAQSLRKDIAAGRFATGARLPAESALAETFGVSRPIVREAIALLKAD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCC
GILVTRKGAGAYVSDTPGGQAWRVASAPDGGPTLAQLFELRMVVETACAEMAAARRTEAD
CEEEEECCCCCEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LLQIREALAGMQDQAGDFAAAAAADIAFHHAIAQAAHNPCVTGLTDFVSQQMLAARQRAW
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ENTARLQVRDGAARAADSEHAALVDAIASGNPATARQAALDHLNAAAGRLGLRLV
HHHHEEEECCCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDILPRPASLANRIAQSLRKDIAAGRFATGARLPAESALAETFGVSRPIVREAIALLKAD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCC
GILVTRKGAGAYVSDTPGGQAWRVASAPDGGPTLAQLFELRMVVETACAEMAAARRTEAD
CEEEEECCCCCEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LLQIREALAGMQDQAGDFAAAAAADIAFHHAIAQAAHNPCVTGLTDFVSQQMLAARQRAW
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ENTARLQVRDGAARAADSEHAALVDAIASGNPATARQAALDHLNAAAGRLGLRLV
HHHHEEEECCCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]