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The map label for this gene is rnz [H]

Identifier: 73540872

GI number: 73540872

Start: 1259857

End: 1260957

Strand: Direct

Name: rnz [H]

Synonym: Reut_A1175

Alternate gene names: 73540872

Gene position: 1259857-1260957 (Clockwise)

Preceding gene: 73540871

Following gene: 73540875

Centisome position: 33.1

GC content: 61.67

Gene sequence:

>1101_bases
ATGGCTGGGAACGGAGGAACTGACGGTGTTCATGGCACCGTGGCCATCATGCGTCACTTGCTGGAAGTCCGCCTCGTCAA
CGATGTCTTTGGCGATCCTGGACTCCTCGTCGACTTCCTGGACGAACGGCGTGCGTTGCTGTTCGATCTGGGCGACATCT
CCGTACTGATGCCGCGCGAGCTGATGCGGCTGTCACAGGTGTTCGTCACGCATGCACACATGGATCATTTCTCCGGCTTC
GACCACCTGCTGCGCGTGTTGCTCGGACGCAAGGATCGAATCGTGCTGTACGGCGGACCAGGATTCCTGGCGCAGATTGA
GCACAAGCTGCACAGCTACACGTGGAATGTGGTCCATCGCTATGCAATCGAGCTCAAGGTTGAAGCGGTCGAACTTGGCT
TGGACTGGCAGCGGCGCAGAGCCTGCTTTTCCAGCCGGCACGGCTTCGCGAAGCAGGGTGAGGTGCCGATGGGGAGTACC
GGCGACATCGTCCACGAGGAGACAACCTTCCGGGTGCGCGCGTGCTTCGTGGATCATGGAACGCCTTGCCTGGCTTATCT
GTTGGAAGAAAAGGCTCGTCCCGGTATCAACAAGGAGCGGCTGGCCGCGTCAGGTCTGACGACAGGAGCCTGGCTGCGCG
AGTTGAAGCACGCTGTCCTGACTGGCGCGCCCGATGATGCGCCGATTCTTGTGCAATGGAGCGATCGCGCGGGCGAGCAT
GCGACGACGCGGCAGGTAGGCGAGCTGAGCCGGTTGATCCTTGATGTCGGATCTGGCCGGCGTATCGGCTACGTCACCGA
CCTGCGCTACTCGGACGAGAATGTGAAAGCGTTGTCGCAATTTATGCAGGGCGTCGACGAGCTCTTCATCGAGAGCGTGT
TTCTGGACCAGGACAGCGCTCACGGTTTGCGCAAGAACCATTTGACCGCAGCCCAGGCCGGCCGGATCGCCCGCTGCACG
GGTGCTCGCGCGGTAACCCCCTTTCATTTCTCGCCACGCTATGAGGGCCGCGCCGCCGAGTTGGCCGCCGAAGTACGGAT
TGCGTGGGCCGGGGATACGCATAGCCAATTCGAGCCACGGCTGCCCGACCGGACGACGTAA

Upstream 100 bases:

>100_bases
TGAAGGCGTGCGGCTCCCGCGGCGTCCCGTTCGTGCGCAGGACACGCGTCTTGGCGGGGCTGGAATTGGCGCATAGGATG
TCGATGTCGAGTTCCCAGAA

Downstream 100 bases:

>100_bases
CGGCGGGGCGTCTCAAGGGCGCCACAAGGGATCGCCGTTAGCGGTGAAGCAACCAGAACAGGACCGACAGCAACAGCGAG
ATCACAATACAAGTAGTGAT

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MAGNGGTDGVHGTVAIMRHLLEVRLVNDVFGDPGLLVDFLDERRALLFDLGDISVLMPRELMRLSQVFVTHAHMDHFSGF
DHLLRVLLGRKDRIVLYGGPGFLAQIEHKLHSYTWNVVHRYAIELKVEAVELGLDWQRRRACFSSRHGFAKQGEVPMGST
GDIVHEETTFRVRACFVDHGTPCLAYLLEEKARPGINKERLAASGLTTGAWLRELKHAVLTGAPDDAPILVQWSDRAGEH
ATTRQVGELSRLILDVGSGRRIGYVTDLRYSDENVKALSQFMQGVDELFIESVFLDQDSAHGLRKNHLTAAQAGRIARCT
GARAVTPFHFSPRYEGRAAELAAEVRIAWAGDTHSQFEPRLPDRTT

Sequences:

>Translated_366_residues
MAGNGGTDGVHGTVAIMRHLLEVRLVNDVFGDPGLLVDFLDERRALLFDLGDISVLMPRELMRLSQVFVTHAHMDHFSGF
DHLLRVLLGRKDRIVLYGGPGFLAQIEHKLHSYTWNVVHRYAIELKVEAVELGLDWQRRRACFSSRHGFAKQGEVPMGST
GDIVHEETTFRVRACFVDHGTPCLAYLLEEKARPGINKERLAASGLTTGAWLRELKHAVLTGAPDDAPILVQWSDRAGEH
ATTRQVGELSRLILDVGSGRRIGYVTDLRYSDENVKALSQFMQGVDELFIESVFLDQDSAHGLRKNHLTAAQAGRIARCT
GARAVTPFHFSPRYEGRAAELAAEVRIAWAGDTHSQFEPRLPDRTT
>Mature_365_residues
AGNGGTDGVHGTVAIMRHLLEVRLVNDVFGDPGLLVDFLDERRALLFDLGDISVLMPRELMRLSQVFVTHAHMDHFSGFD
HLLRVLLGRKDRIVLYGGPGFLAQIEHKLHSYTWNVVHRYAIELKVEAVELGLDWQRRRACFSSRHGFAKQGEVPMGSTG
DIVHEETTFRVRACFVDHGTPCLAYLLEEKARPGINKERLAASGLTTGAWLRELKHAVLTGAPDDAPILVQWSDRAGEHA
TTRQVGELSRLILDVGSGRRIGYVTDLRYSDENVKALSQFMQGVDELFIESVFLDQDSAHGLRKNHLTAAQAGRIARCTG
ARAVTPFHFSPRYEGRAAELAAEVRIAWAGDTHSQFEPRLPDRTT

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 40806; Mature: 40675

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNGGTDGVHGTVAIMRHLLEVRLVNDVFGDPGLLVDFLDERRALLFDLGDISVLMPRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCCCEEECCHH
LMRLSQVFVTHAHMDHFSGFDHLLRVLLGRKDRIVLYGGPGFLAQIEHKLHSYTWNVVHR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHE
YAIELKVEAVELGLDWQRRRACFSSRHGFAKQGEVPMGSTGDIVHEETTFRVRACFVDHG
EEEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCC
TPCLAYLLEEKARPGINKERLAASGLTTGAWLRELKHAVLTGAPDDAPILVQWSDRAGEH
CHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
ATTRQVGELSRLILDVGSGRRIGYVTDLRYSDENVKALSQFMQGVDELFIESVFLDQDSA
HHHHHHHHHHHHHHCCCCCCEEEEEEECEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HGLRKNHLTAAQAGRIARCTGARAVTPFHFSPRYEGRAAELAAEVRIAWAGDTHSQFEPR
CCCHHHCCCHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCCCCCC
LPDRTT
CCCCCC
>Mature Secondary Structure 
AGNGGTDGVHGTVAIMRHLLEVRLVNDVFGDPGLLVDFLDERRALLFDLGDISVLMPRE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCCCEEECCHH
LMRLSQVFVTHAHMDHFSGFDHLLRVLLGRKDRIVLYGGPGFLAQIEHKLHSYTWNVVHR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHE
YAIELKVEAVELGLDWQRRRACFSSRHGFAKQGEVPMGSTGDIVHEETTFRVRACFVDHG
EEEEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCC
TPCLAYLLEEKARPGINKERLAASGLTTGAWLRELKHAVLTGAPDDAPILVQWSDRAGEH
CHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
ATTRQVGELSRLILDVGSGRRIGYVTDLRYSDENVKALSQFMQGVDELFIESVFLDQDSA
HHHHHHHHHHHHHHCCCCCCEEEEEEECEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HGLRKNHLTAAQAGRIARCTGARAVTPFHFSPRYEGRAAELAAEVRIAWAGDTHSQFEPR
CCCHHHCCCHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCCCCCC
LPDRTT
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]