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The map label for this gene is uvrY [H]

Identifier: 73540845

GI number: 73540845

Start: 1238093

End: 1238722

Strand: Direct

Name: uvrY [H]

Synonym: Reut_A1146

Alternate gene names: 73540845

Gene position: 1238093-1238722 (Clockwise)

Preceding gene: 73540844

Following gene: 73540848

Centisome position: 32.53

GC content: 63.02

Gene sequence:

>630_bases
ATGACGCGCGTGCTCATTGCCGATGACCATGCCGTCGTGCGCGACGGTCTCAAGCATATCCTGGAGCGCGCCGGCAAATT
CGATGTGGTAGGCGAAGCCGCCGACGGCAGCCAGGTCCTGAAGCTCGTGCGCGACTGCGCGCCGCAGGTGCTGCTGCTCG
ACTTGTCGATGCCAGGCCGCAGCGGCCTGGAACTGATCCGCCTGTTGCGGGACGAGCAACAGGCGCTGCGCATCCTGGTA
CTGACCATGCATGCGGAGCAGCAATACATCGTGCGCGCGTTCCAGGCCGGTGCGGCGGGCTATCTGACCAAGGAAAGCGC
TGCGACCGAGCTGGTTTCGGCGATCACCCAGGTGGCAAGCGGGGGCACGTATGTCAGCCAGGCAATTGCCGGCAAGCTGG
CGACCAGCCTGGAACATCAGGACGAAGCACCGCACTTGCGCCTGTCCGACCGGCATGAGCAACGTCATAGGTTTATCGCA
GATCGAGTGCTTCAAGATCCAGCAGTTCGATCTGCTTGCCCTGTACCCGAATCAGTCCTTCCTGCTGGAAGCGCGACAGC
GTGCGGCTCGCGGTCTCCAGGGTCATGCCCAGATAACTGCCGATGTCCTCGCGCGTCATGCGCAACGTAA

Upstream 100 bases:

>100_bases
CGAAGGAAGCTGTCGCGCCAGCAACGGACTGGCCGCCCTCTGCGACTCCGACCTGAAGGTCGTTCATGTGATCGGATTCC
TCTGGAAAAAGGGTTATGAA

Downstream 100 bases:

>100_bases
AGCATGTCGGCGAATAGCCCCTGCGCTGCAGGCGACGCGAGATGTTGAGCAGGAAGGCCGCCACGCGCTGCTCCGCCGTG
AGGTTGCCGAGCAGCATCAT

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTRVLIADDHAVVRDGLKHILERAGKFDVVGEAADGSQVLKLVRDCAPQVLLLDLSMPGRSGLELIRLLRDEQQALRILV
LTMHAEQQYIVRAFQAGAAGYLTKESAATELVSAITQVASGGTYVSQAIAGKLATSLEHQDEAPHLRLSDRHEQRHRFIA
DRVLQDPAVRSACPVPESVLPAGSATACGSRSPGSCPDNCRCPRASCAT

Sequences:

>Translated_209_residues
MTRVLIADDHAVVRDGLKHILERAGKFDVVGEAADGSQVLKLVRDCAPQVLLLDLSMPGRSGLELIRLLRDEQQALRILV
LTMHAEQQYIVRAFQAGAAGYLTKESAATELVSAITQVASGGTYVSQAIAGKLATSLEHQDEAPHLRLSDRHEQRHRFIA
DRVLQDPAVRSACPVPESVLPAGSATACGSRSPGSCPDNCRCPRASCAT
>Mature_208_residues
TRVLIADDHAVVRDGLKHILERAGKFDVVGEAADGSQVLKLVRDCAPQVLLLDLSMPGRSGLELIRLLRDEQQALRILVL
TMHAEQQYIVRAFQAGAAGYLTKESAATELVSAITQVASGGTYVSQAIAGKLATSLEHQDEAPHLRLSDRHEQRHRFIAD
RVLQDPAVRSACPVPESVLPAGSATACGSRSPGSCPDNCRCPRASCAT

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=156, Percent_Identity=42.9487179487179, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787473, Length=134, Percent_Identity=38.0597014925373, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790102, Length=170, Percent_Identity=32.3529411764706, Blast_Score=80, Evalue=7e-17,
Organism=Escherichia coli, GI1788521, Length=127, Percent_Identity=35.4330708661417, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1786747, Length=180, Percent_Identity=22.7777777777778, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788546, Length=131, Percent_Identity=29.7709923664122, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082052, Length=104, Percent_Identity=33.6538461538462, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=31.3559322033898, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=33.0508474576271, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22415; Mature: 22284

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVLIADDHAVVRDGLKHILERAGKFDVVGEAADGSQVLKLVRDCAPQVLLLDLSMPGR
CCEEEEECCHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHCCCCEEEEECCCCCH
SGLELIRLLRDEQQALRILVLTMHAEQQYIVRAFQAGAAGYLTKESAATELVSAITQVAS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
GGTYVSQAIAGKLATSLEHQDEAPHLRLSDRHEQRHRFIADRVLQDPAVRSACPVPESVL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHC
PAGSATACGSRSPGSCPDNCRCPRASCAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRVLIADDHAVVRDGLKHILERAGKFDVVGEAADGSQVLKLVRDCAPQVLLLDLSMPGR
CEEEEECCHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHCCCCEEEEECCCCCH
SGLELIRLLRDEQQALRILVLTMHAEQQYIVRAFQAGAAGYLTKESAATELVSAITQVAS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
GGTYVSQAIAGKLATSLEHQDEAPHLRLSDRHEQRHRFIADRVLQDPAVRSACPVPESVL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHC
PAGSATACGSRSPGSCPDNCRCPRASCAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]