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The map label for this gene is hrcA [H]

Identifier: 73540739

GI number: 73540739

Start: 1130962

End: 1131999

Strand: Direct

Name: hrcA [H]

Synonym: Reut_A1036

Alternate gene names: 73540739

Gene position: 1130962-1131999 (Clockwise)

Preceding gene: 73540734

Following gene: 73540740

Centisome position: 29.71

GC content: 63.87

Gene sequence:

>1038_bases
ATGGATGAACGTTCCAAAACGCTGCTCAAGACCCTGATCGAGCGCTACATTGCCGAAGGCCAGCCGGTCGGTTCCCGGAC
CTTGTCCAAGTATTCCGGACTGGACCTGTCGCCGGCCACCATCCGCAATGTGATGTCCGATCTGGAGGAGATGGGCTTCA
TCTCCAGTCCGCATACGTCGGCGGGGCGGATCCCCACGCCGCGCGGGTATCGCCTGTTCGTCGACACCATGCTGACGGTC
AAGCCGATCGAGCGCGGCGGCCTGGAAATGACCGAACTGGCCGGCCAGATCCAGGGCCAGCTCGGCGGCCAGCAACTCGG
GCCGCAGCGCATGATCACGGCGGCGGCGCGCACGCTGTCGAACCTCTCGCACTTCGCCGGCGTAGTCATGACCCCGCGGC
GCGCGCAGTCGTTCCGGCAGGTCGAATTCATGCGGTTGTCGGACAAGCGCATCCTGCTGATCATCGTCAGCCCGGAAGGC
GACGTGCAGAACCGGATCATCCAGACCGAACTGTCGTACACGCCGGCGCAGCTGATCGAAGCGGCGAACTTCTTCAACGC
GCACTATGCGGGCATGAGCTTCGATGCCGTGCGCGACCACCTGCGCGTGGAGCTGCAGGACCTGCGCCGCGACATGTCGC
AGTTGATGCAGGCGGCGGTCGAGGCAGGCAGCAGCGCCATGGAAGAAGAAGACGACCACCTCTATATCAGCGGCGAACGC
AAGCTGCTCGAGGTCGAGGACCTGGCTTCCAGCATGGACAAGCTGCGGCGGCTGTTCGATGTGTTCGAGCACAAGACCAG
CCTGCTCCAGCTTCTGGACGTGTCCAGCCATGCTCAGGGCGTGCAGATCTTCATCGGCGGCGAAAGCCAGCTCGTGCCGA
TCGAGGAAATGGCCGTGATCACCGCGCCCTATGAGGTCGACGGGCAGATCGTCGGTACGCTGGGGGTCATCGGCCCGACC
CGCATGGCCTATGAGCGCGTGATTCCGATTGTCGACATCACCGCGCGCCTGCTCTCGAGTGCACTGAGCCAGAACTAG

Upstream 100 bases:

>100_bases
CCATACCGCTGTGACCGTTGTCAGCATGGGCCGGGCGCGCCACCGGGCACCGGCCGCGCGGGCGCCCGAAGCTGTAAAAC
TTGCGTAAAATCGGGGCATC

Downstream 100 bases:

>100_bases
GACCCGTCCGACGGGTCACACAGTCTGCGTCCCCATTTCCACAGCCCGGCGGCCTTGGCTGCCCGGCCATACCGGAAGCG
ACATGACGTTTTCTCCCGAA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MDERSKTLLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFISSPHTSAGRIPTPRGYRLFVDTMLTV
KPIERGGLEMTELAGQIQGQLGGQQLGPQRMITAAARTLSNLSHFAGVVMTPRRAQSFRQVEFMRLSDKRILLIIVSPEG
DVQNRIIQTELSYTPAQLIEAANFFNAHYAGMSFDAVRDHLRVELQDLRRDMSQLMQAAVEAGSSAMEEEDDHLYISGER
KLLEVEDLASSMDKLRRLFDVFEHKTSLLQLLDVSSHAQGVQIFIGGESQLVPIEEMAVITAPYEVDGQIVGTLGVIGPT
RMAYERVIPIVDITARLLSSALSQN

Sequences:

>Translated_345_residues
MDERSKTLLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFISSPHTSAGRIPTPRGYRLFVDTMLTV
KPIERGGLEMTELAGQIQGQLGGQQLGPQRMITAAARTLSNLSHFAGVVMTPRRAQSFRQVEFMRLSDKRILLIIVSPEG
DVQNRIIQTELSYTPAQLIEAANFFNAHYAGMSFDAVRDHLRVELQDLRRDMSQLMQAAVEAGSSAMEEEDDHLYISGER
KLLEVEDLASSMDKLRRLFDVFEHKTSLLQLLDVSSHAQGVQIFIGGESQLVPIEEMAVITAPYEVDGQIVGTLGVIGPT
RMAYERVIPIVDITARLLSSALSQN
>Mature_345_residues
MDERSKTLLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFISSPHTSAGRIPTPRGYRLFVDTMLTV
KPIERGGLEMTELAGQIQGQLGGQQLGPQRMITAAARTLSNLSHFAGVVMTPRRAQSFRQVEFMRLSDKRILLIIVSPEG
DVQNRIIQTELSYTPAQLIEAANFFNAHYAGMSFDAVRDHLRVELQDLRRDMSQLMQAAVEAGSSAMEEEDDHLYISGER
KLLEVEDLASSMDKLRRLFDVFEHKTSLLQLLDVSSHAQGVQIFIGGESQLVPIEEMAVITAPYEVDGQIVGTLGVIGPT
RMAYERVIPIVDITARLLSSALSQN

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38250; Mature: 38250

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERSKTLLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFISSPHTS
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
AGRIPTPRGYRLFVDTMLTVKPIERGGLEMTELAGQIQGQLGGQQLGPQRMITAAARTLS
CCCCCCCCCCEEEEEHHHHEEEHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
NLSHFAGVVMTPRRAQSFRQVEFMRLSDKRILLIIVSPEGDVQNRIIQTELSYTPAQLIE
HHHHHHHHEECCHHHHHHHHHHHHEECCCEEEEEEECCCCCHHHHEEHHHCCCCHHHHHH
AANFFNAHYAGMSFDAVRDHLRVELQDLRRDMSQLMQAAVEAGSSAMEEEDDHLYISGER
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEECCC
KLLEVEDLASSMDKLRRLFDVFEHKTSLLQLLDVSSHAQGVQIFIGGESQLVPIEEMAVI
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHEEE
TAPYEVDGQIVGTLGVIGPTRMAYERVIPIVDITARLLSSALSQN
ECCCCCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDERSKTLLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFISSPHTS
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
AGRIPTPRGYRLFVDTMLTVKPIERGGLEMTELAGQIQGQLGGQQLGPQRMITAAARTLS
CCCCCCCCCCEEEEEHHHHEEEHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
NLSHFAGVVMTPRRAQSFRQVEFMRLSDKRILLIIVSPEGDVQNRIIQTELSYTPAQLIE
HHHHHHHHEECCHHHHHHHHHHHHEECCCEEEEEEECCCCCHHHHEEHHHCCCCHHHHHH
AANFFNAHYAGMSFDAVRDHLRVELQDLRRDMSQLMQAAVEAGSSAMEEEDDHLYISGER
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEECCC
KLLEVEDLASSMDKLRRLFDVFEHKTSLLQLLDVSSHAQGVQIFIGGESQLVPIEEMAVI
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHEEE
TAPYEVDGQIVGTLGVIGPTRMAYERVIPIVDITARLLSSALSQN
ECCCCCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]