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The map label for this gene is amiC [H]

Identifier: 73540689

GI number: 73540689

Start: 1074351

End: 1075607

Strand: Direct

Name: amiC [H]

Synonym: Reut_A0986

Alternate gene names: 73540689

Gene position: 1074351-1075607 (Clockwise)

Preceding gene: 73540688

Following gene: 73540690

Centisome position: 28.22

GC content: 61.58

Gene sequence:

>1257_bases
ATGAAACGACGTGACATGCTGAAGCTGTCGGCGGTAGCCGCCGCGGCGATGATCAGCGCCAGCCCGCTGGCGATGGCGCA
GTCCAAGGAACCGATCAAGGTCGGCATCCTCCATTCGCTGTCGGGCACCATGGCCATTTCGGAGACGTCGCTCAAGGACG
TGGCCCTGATGACCATCGACGAGATCAACAAGAGCGGCGGCGTGCTCGGCCGCAAGCTCGAGCCCGTGGTCGTGGATCCG
GCATCAAACTGGCCGCTGTTCGCCGAGAAGGCGCGCCAGCTGATTACCAAGGACAAGGTCGCTGTCACGTTCGGCTGCTG
GACTTCGGTGTCGCGCAAGTCGGTGCTGCCGGTCTACGAGGAACTGAACTCGCTGCTGTTCTACCCCGTGCAGTATGAAG
GCGAGGAGATGTCCAAGAACGTCTTCTACACCGGCGCGGCGCCCAACCAGCAGGCCATCCCGGCGGTCGAGTACCTGATG
AGCAAGGAAGGTGGCGGCGCGAAGCGCTTCTTCCTGCTTGGCACCGACTACGTCTACCCGCGCACCACCAACAAGATCCT
GCGCGCGTTCCTGAAGAGCAAGGGCGTGGCGGACAAGGATATCGAAGAGGTCTACACGCCGTTCGGCCACAGCGACTACC
AGACCATCGTCGCGAATATCAAGAAGTTCTCGCAGGGCGGAAAAACGGCTGTGATCTCGACCATCAACGGTGACTCCAAC
GTGCCGTTCTACAAGGAGCTCGGCAACGCCGGCCTGAAGGCCAAGGACGTGCCGGTGGTGGCCTTCTCGGTGGGTGAGGA
AGAACTGCGCGGCATCGACACCAAGCCGCTGGTCGGCCACCTGGCCGCATGGAACTACTTCATGTCGGTCAAGAACCCCG
AGAACGAAGCGTTCAAGAAGCAATGGGCGGCATGGGTCAAGGCGAACAACCTTCCTGGTGGCGACAAGCGCGTGACCAAT
GACCCGATGGAAGCCACTTACGTCGGCATCCACATGTGGGCGCAGGCCGTGAAGAAGGCCGGCACGACCGATCCGGACAA
GGTCCGCGCGGCCATGTATGGCCAGACTTTCAAGGCACCGGACGGCTTCACGCTGACCATGGGCGACAACCATCATCTGT
ACAAGCCGGTGATGATTGGCGAGGTTAAGGGCGACGGCCAGTTCACGGTGGTGTGGAAGACCGCGAAGCCGATCCGCGCG
CAGCCTTGGAGCCCGTTCATCTCCGGCAATGAAGGCAAGCCGGACAAGGTGATGTAA

Upstream 100 bases:

>100_bases
GTCGTCTTCCGCCGTCTCGGTACGCCATGGCACGCTAGTTGCAGATGCATCACCCGGGGTGCGTTGAGTCCCGTAACCAA
ACGACAAACTGGGAGCTGCA

Downstream 100 bases:

>100_bases
GGCAGCCAGTCGCTGCACCCCTGGCAGGCGCGCTCCGCCGGCTGACCGTTGCCGGCTGGCGGTGGTGCGCGCCTGACCGG
GCCTGGGGGGGTCCCCGAAA

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKRRDMLKLSAVAAAAMISASPLAMAQSKEPIKVGILHSLSGTMAISETSLKDVALMTIDEINKSGGVLGRKLEPVVVDP
ASNWPLFAEKARQLITKDKVAVTFGCWTSVSRKSVLPVYEELNSLLFYPVQYEGEEMSKNVFYTGAAPNQQAIPAVEYLM
SKEGGGAKRFFLLGTDYVYPRTTNKILRAFLKSKGVADKDIEEVYTPFGHSDYQTIVANIKKFSQGGKTAVISTINGDSN
VPFYKELGNAGLKAKDVPVVAFSVGEEELRGIDTKPLVGHLAAWNYFMSVKNPENEAFKKQWAAWVKANNLPGGDKRVTN
DPMEATYVGIHMWAQAVKKAGTTDPDKVRAAMYGQTFKAPDGFTLTMGDNHHLYKPVMIGEVKGDGQFTVVWKTAKPIRA
QPWSPFISGNEGKPDKVM

Sequences:

>Translated_418_residues
MKRRDMLKLSAVAAAAMISASPLAMAQSKEPIKVGILHSLSGTMAISETSLKDVALMTIDEINKSGGVLGRKLEPVVVDP
ASNWPLFAEKARQLITKDKVAVTFGCWTSVSRKSVLPVYEELNSLLFYPVQYEGEEMSKNVFYTGAAPNQQAIPAVEYLM
SKEGGGAKRFFLLGTDYVYPRTTNKILRAFLKSKGVADKDIEEVYTPFGHSDYQTIVANIKKFSQGGKTAVISTINGDSN
VPFYKELGNAGLKAKDVPVVAFSVGEEELRGIDTKPLVGHLAAWNYFMSVKNPENEAFKKQWAAWVKANNLPGGDKRVTN
DPMEATYVGIHMWAQAVKKAGTTDPDKVRAAMYGQTFKAPDGFTLTMGDNHHLYKPVMIGEVKGDGQFTVVWKTAKPIRA
QPWSPFISGNEGKPDKVM
>Mature_418_residues
MKRRDMLKLSAVAAAAMISASPLAMAQSKEPIKVGILHSLSGTMAISETSLKDVALMTIDEINKSGGVLGRKLEPVVVDP
ASNWPLFAEKARQLITKDKVAVTFGCWTSVSRKSVLPVYEELNSLLFYPVQYEGEEMSKNVFYTGAAPNQQAIPAVEYLM
SKEGGGAKRFFLLGTDYVYPRTTNKILRAFLKSKGVADKDIEEVYTPFGHSDYQTIVANIKKFSQGGKTAVISTINGDSN
VPFYKELGNAGLKAKDVPVVAFSVGEEELRGIDTKPLVGHLAAWNYFMSVKNPENEAFKKQWAAWVKANNLPGGDKRVTN
DPMEATYVGIHMWAQAVKKAGTTDPDKVRAAMYGQTFKAPDGFTLTMGDNHHLYKPVMIGEVKGDGQFTVVWKTAKPIRA
QPWSPFISGNEGKPDKVM

Specific function: Negatively regulates the expression of the aliphatic amidase operon. AmiC functions by inhibiting the action of AmiR at the protein level. It exhibits protein kinase activity [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000709 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45827; Mature: 45827

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRDMLKLSAVAAAAMISASPLAMAQSKEPIKVGILHSLSGTMAISETSLKDVALMTID
CCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCCEEEECCCCCCEEEEEHH
EINKSGGVLGRKLEPVVVDPASNWPLFAEKARQLITKDKVAVTFGCWTSVSRKSVLPVYE
HHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHH
ELNSLLFYPVQYEGEEMSKNVFYTGAAPNQQAIPAVEYLMSKEGGGAKRFFLLGTDYVYP
HCCCCEEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCEECC
RTTNKILRAFLKSKGVADKDIEEVYTPFGHSDYQTIVANIKKFSQGGKTAVISTINGDSN
CCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCC
VPFYKELGNAGLKAKDVPVVAFSVGEEELRGIDTKPLVGHLAAWNYFMSVKNPENEAFKK
CCHHHHHCCCCCCCCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHEEEEECCCCHHHHHH
QWAAWVKANNLPGGDKRVTNDPMEATYVGIHMWAQAVKKAGTTDPDKVRAAMYGQTFKAP
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEECCC
DGFTLTMGDNHHLYKPVMIGEVKGDGQFTVVWKTAKPIRAQPWSPFISGNEGKPDKVM
CCEEEEECCCCEEECCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRRDMLKLSAVAAAAMISASPLAMAQSKEPIKVGILHSLSGTMAISETSLKDVALMTID
CCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCCEEEECCCCCCEEEEEHH
EINKSGGVLGRKLEPVVVDPASNWPLFAEKARQLITKDKVAVTFGCWTSVSRKSVLPVYE
HHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHH
ELNSLLFYPVQYEGEEMSKNVFYTGAAPNQQAIPAVEYLMSKEGGGAKRFFLLGTDYVYP
HCCCCEEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCEECC
RTTNKILRAFLKSKGVADKDIEEVYTPFGHSDYQTIVANIKKFSQGGKTAVISTINGDSN
CCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCC
VPFYKELGNAGLKAKDVPVVAFSVGEEELRGIDTKPLVGHLAAWNYFMSVKNPENEAFKK
CCHHHHHCCCCCCCCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHEEEEECCCCHHHHHH
QWAAWVKANNLPGGDKRVTNDPMEATYVGIHMWAQAVKKAGTTDPDKVRAAMYGQTFKAP
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEECCC
DGFTLTMGDNHHLYKPVMIGEVKGDGQFTVVWKTAKPIRAQPWSPFISGNEGKPDKVM
CCEEEEECCCCEEECCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1907262; 10984043; 1762155; 7813419; 10508151; 10708652 [H]