Click here to switch to the map view.

The map label for this gene is nuoA

Identifier: 73540664

GI number: 73540664

Start: 1049360

End: 1049719

Strand: Direct

Name: nuoA

Synonym: Reut_A0961

Alternate gene names: 73540664

Gene position: 1049360-1049719 (Clockwise)

Preceding gene: 73540663

Following gene: 73540665

Centisome position: 27.57

GC content: 56.11

Gene sequence:

>360_bases
TTGACTCTCGAAGCCTACTTCCCCGTTCTCATCTTCATCATCTTCGGCGTCGTGCTTGGCATCGCGCTGATGTCGATTGG
TCGGATCCTCGGTCCGAACAAGCCTGATCCTGCGAAGCTGTCGCCGTACGAGTGCGGCTTCGAAGCGTTCGAGGATGCGC
GCATGAAGTTCGACGTGCGCTATTACCTCATCGCCATCCTTTTTATCCTGTTCGATCTCGAAACCGCCTTCCTGTTTCCG
TGGGGTGTTGCCCTGCGTGAAATCGGCTGGCCGGGATTCATCGCCATGGGCGTGTTTCTGCTGGAATTCATCGTGGGCTT
CGTCTACATCTGGAAAAAGGGCGCGCTCGATTGGGAGTGA

Upstream 100 bases:

>100_bases
CGGCGCGCCGTGAGGTCTTCGGCTTAGCGCCTGGGGTGGGCAACAGGACGCCGCTTCAGCTGGTGCTGTTGACAACATTC
CAGATAAGGCTGGCCGCATC

Downstream 100 bases:

>100_bases
TGTGAAATGGCAATCGAAGGCGTTCTCAACGAAGGCTTTGTCACGACTACCGCTGACAAGCTGATCAACTGGACCCGCAC
CGGGTCGCTGTGGCCGATGA

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MTLEAYFPVLIFIIFGVVLGIALMSIGRILGPNKPDPAKLSPYECGFEAFEDARMKFDVRYYLIAILFILFDLETAFLFP
WGVALREIGWPGFIAMGVFLLEFIVGFVYIWKKGALDWE

Sequences:

>Translated_119_residues
MTLEAYFPVLIFIIFGVVLGIALMSIGRILGPNKPDPAKLSPYECGFEAFEDARMKFDVRYYLIAILFILFDLETAFLFP
WGVALREIGWPGFIAMGVFLLEFIVGFVYIWKKGALDWE
>Mature_118_residues
TLEAYFPVLIFIIFGVVLGIALMSIGRILGPNKPDPAKLSPYECGFEAFEDARMKFDVRYYLIAILFILFDLETAFLFPW
GVALREIGWPGFIAMGVFLLEFIVGFVYIWKKGALDWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=108, Percent_Identity=35.1851851851852, Blast_Score=84, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_CUPPJ (Q473U3)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_295184.1
- GeneID:   3609357
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0961
- NMPDR:   fig|264198.3.peg.1361
- HOGENOM:   HBG605540
- OMA:   IGFAYEW
- ProtClustDB:   PRK06602
- BioCyc:   REUT264198:REUT_A0961-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13611; Mature: 13480

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xde84684)-; HASH(0xec9245c)-; HASH(0xf20d920)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEAYFPVLIFIIFGVVLGIALMSIGRILGPNKPDPAKLSPYECGFEAFEDARMKFDVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHHHHH
YYLIAILFILFDLETAFLFPWGVALREIGWPGFIAMGVFLLEFIVGFVYIWKKGALDWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
TLEAYFPVLIFIIFGVVLGIALMSIGRILGPNKPDPAKLSPYECGFEAFEDARMKFDVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHHHHH
YYLIAILFILFDLETAFLFPWGVALREIGWPGFIAMGVFLLEFIVGFVYIWKKGALDWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA