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The map label for this gene is gluQ [H]

Identifier: 73540603

GI number: 73540603

Start: 982625

End: 983530

Strand: Reverse

Name: gluQ [H]

Synonym: Reut_A0900

Alternate gene names: 73540603

Gene position: 983530-982625 (Counterclockwise)

Preceding gene: 73540604

Following gene: 73540601

Centisome position: 25.84

GC content: 68.32

Gene sequence:

>906_bases
ATGACAGTATCCGCCGGCCGCTACCGCGGCCGCTTCGCCCCCTCGCCCACCGGTCCGCTGCACATGGGTTCGCTGGTGAC
CGCGCTGGCCACGTGGCTGGATGCGCGCGCGCATGGCGGCCAGTGGCTGGTACGGATCGAGGACATCGACTATCCGCGCT
GCGTGCGCGGTGCCGACATTGAGATTCTGGAGACGCTGGAACGGCTGGGACTCGTGCCCGACGAACCGCCGGTCTGGCAA
AGCCGGCGAGAGGCGCTATACGCCGACGCGCTGCATCGGCTGGATGCCGCAGGCCAGCTCTACCCGTGCGGCTGCTCGCG
CAAGGAGATTGCCGATTCGCTGCTGCATGTGCGCGAACGGCACCAGACGCTCGGCTATCCGGGTACATGCCGCCACGGGC
TCAATGGCAAGTTGCCCCGCGCGTGGCGCGTGCGCGTGCCGGACGGACCGGCCGCCACCATCTGCTTCGATGACCGCTGG
CAGGGCCGGCAATGCCAGGACCTGGAAACGGAAGTGGGCGACTTCGTACTGCGCCGCGCCGACGGGCTATGGGCGTACCA
GCTGGCGGTGGTGGTCGACGACGGCCTGCAGGGCATCACGCACATCGTGCGCGGCGCCGATCTGCTCGACTCCACGCCAC
GCCAGATTCACCTGCAACACCTGCTCGGATTGCCGACGCCCAGCTATTTGCACGTGCCTGTGGTCGTCAACGCGATCGGC
GAAAAATTGAGCAAACAGAGTGGCGCGCAGGCGATCGACACCAATGCGCCACTCGATGCGTTGCGAGCGGCCGGGGATCA
CCTCGGGCTACGGAATGACGGGAACGATGTGAAGGCGTGGCTCGAACGCGCCACCGGGGACTGGCTGCAGCGCCTGGCGA
CGCTGCCCGCCGCGGCCGGGCGCTGA

Upstream 100 bases:

>100_bases
GGTGGGCCGACAAGCTGGAAGACCCGCGACTCGCACAGGCGCTGCTGCAGCAGCAACCCGAGCTGGGCGGTTAAGGCGCG
ACTGAGCGGGAAATACACGC

Downstream 100 bases:

>100_bases
TTCACAGCCCGGCTTCACGGCATTTCACTAAAGGACGATCAGGACTTGCGCGGCGCGCCGCCGAGCAATGCGGCAACCGG
CCGCTTGGGCGCCTGGCGGC

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTVSAGRYRGRFAPSPTGPLHMGSLVTALATWLDARAHGGQWLVRIEDIDYPRCVRGADIEILETLERLGLVPDEPPVWQ
SRREALYADALHRLDAAGQLYPCGCSRKEIADSLLHVRERHQTLGYPGTCRHGLNGKLPRAWRVRVPDGPAATICFDDRW
QGRQCQDLETEVGDFVLRRADGLWAYQLAVVVDDGLQGITHIVRGADLLDSTPRQIHLQHLLGLPTPSYLHVPVVVNAIG
EKLSKQSGAQAIDTNAPLDALRAAGDHLGLRNDGNDVKAWLERATGDWLQRLATLPAAAGR

Sequences:

>Translated_301_residues
MTVSAGRYRGRFAPSPTGPLHMGSLVTALATWLDARAHGGQWLVRIEDIDYPRCVRGADIEILETLERLGLVPDEPPVWQ
SRREALYADALHRLDAAGQLYPCGCSRKEIADSLLHVRERHQTLGYPGTCRHGLNGKLPRAWRVRVPDGPAATICFDDRW
QGRQCQDLETEVGDFVLRRADGLWAYQLAVVVDDGLQGITHIVRGADLLDSTPRQIHLQHLLGLPTPSYLHVPVVVNAIG
EKLSKQSGAQAIDTNAPLDALRAAGDHLGLRNDGNDVKAWLERATGDWLQRLATLPAAAGR
>Mature_300_residues
TVSAGRYRGRFAPSPTGPLHMGSLVTALATWLDARAHGGQWLVRIEDIDYPRCVRGADIEILETLERLGLVPDEPPVWQS
RREALYADALHRLDAAGQLYPCGCSRKEIADSLLHVRERHQTLGYPGTCRHGLNGKLPRAWRVRVPDGPAATICFDDRWQ
GRQCQDLETEVGDFVLRRADGLWAYQLAVVVDDGLQGITHIVRGADLLDSTPRQIHLQHLLGLPTPSYLHVPVVVNAIGE
KLSKQSGAQAIDTNAPLDALRAAGDHLGLRNDGNDVKAWLERATGDWLQRLATLPAAAGR

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=256, Percent_Identity=36.71875, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI226510925, Length=299, Percent_Identity=43.4782608695652, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1788743, Length=251, Percent_Identity=37.0517928286853, Blast_Score=156, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71993394, Length=280, Percent_Identity=32.8571428571429, Blast_Score=123, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6324540, Length=263, Percent_Identity=36.1216730038023, Blast_Score=152, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24665321, Length=259, Percent_Identity=35.1351351351351, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 33104; Mature: 32973

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSAGRYRGRFAPSPTGPLHMGSLVTALATWLDARAHGGQWLVRIEDIDYPRCVRGADI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCH
EILETLERLGLVPDEPPVWQSRREALYADALHRLDAAGQLYPCGCSRKEIADSLLHVRER
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHH
HQTLGYPGTCRHGLNGKLPRAWRVRVPDGPAATICFDDRWQGRQCQDLETEVGDFVLRRA
HHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHC
DGLWAYQLAVVVDDGLQGITHIVRGADLLDSTPRQIHLQHLLGLPTPSYLHVPVVVNAIG
CCCEEEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHH
EKLSKQSGAQAIDTNAPLDALRAAGDHLGLRNDGNDVKAWLERATGDWLQRLATLPAAAG
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
R
C
>Mature Secondary Structure 
TVSAGRYRGRFAPSPTGPLHMGSLVTALATWLDARAHGGQWLVRIEDIDYPRCVRGADI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCH
EILETLERLGLVPDEPPVWQSRREALYADALHRLDAAGQLYPCGCSRKEIADSLLHVRER
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHH
HQTLGYPGTCRHGLNGKLPRAWRVRVPDGPAATICFDDRWQGRQCQDLETEVGDFVLRRA
HHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHC
DGLWAYQLAVVVDDGLQGITHIVRGADLLDSTPRQIHLQHLLGLPTPSYLHVPVVVNAIG
CCCEEEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHH
EKLSKQSGAQAIDTNAPLDALRAAGDHLGLRNDGNDVKAWLERATGDWLQRLATLPAAAG
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA