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The map label for this gene is glnS [H]

Identifier: 73540536

GI number: 73540536

Start: 899710

End: 901539

Strand: Reverse

Name: glnS [H]

Synonym: Reut_A0833

Alternate gene names: 73540536

Gene position: 901539-899710 (Counterclockwise)

Preceding gene: 73540538

Following gene: 73540535

Centisome position: 23.68

GC content: 63.72

Gene sequence:

>1830_bases
ATGAAATTGGCAATCCGCCACGCAACACTGAAGACCAAGCGGTCCATCCAGCCGCTAGCCGGCGCCACCATGAGCCACGA
CAACAAGCCTACCGACAGCACGCCCGCCTCGCCCGCAGTCTCCAACTTTCTGCGGAGCATCATTGACCAGGATCTCGCAG
CCGGCACGTACGCCGGCCGCCAGGACAGCCAGGGCGAGCCGCTGCCGACCGTCATCACCCGCTTTCCGCCGGAGCCCAAC
GGCTACTTGCATATCGGCCATGCCAAGAGCATCTGCCTGAACTTCGGCCTCGCGCGCGACTACGGCGGCCGCTGCCACCT
GCGCTTCGACGACACCAATCCGGTCAAGGAAGACACCGAATACGTCGACTCGATCATCGACGCGGTGCACTGGCTCGGCT
TTTCCTGGGACAGCAAGACCCCGGGCGGCCAGCCGCACCTGCATTATGCGAGCGACTACTTCGACCAGCTGTACGCATTT
GCCGAAAAGCTGATCGAGCGCGGCGCCGCCTATGTCGACAGCCAGAGCGCGGAGCAGATCGCCGCCAACCGTGGCAATTT
CTCGGAGCCGGGCAAGCCGTCGCCATTCCGCGACCGCAGCGTCGAGGAGAACCTGCAGCTGTTCCGCGATATGCGCGACG
GCAAGTACAAGGACGGCGAGCACGTGCTGCGCGCGAAGATCGACATGACCGCGCCGAACATCGTGATGCGCGATCCAGTG
ATCTACCGTATCCGCCATGCCCATCACCACCGTACTGGCGACAAGTGGTGCATCTACCCGATGTACGACTTCACGCACTG
TATTTCGGATGCGATCGAGAACATCTCGCATTCGCTGTGCACGCTCGAGTTCGAGAACAATCGCCCGCTGTACGACTGGG
TGCTCGAGCATCTGCGCGACGCTGGCGTGTTCCGCGATCCGCTGCCGCACCAGTATGAATTCGCGCGCCTGAACCTGACC
TACGCGATCACCAGCAAGCGCAAGCTCAAGCAACTGGTGGACGAACAGCGCGTGGACGGCTGGGACGATCCGCGCATGCC
GACCATCGTCGGTATCCGCCGCCGCGGCTACACGCCGGAATCGATCCAGCTGTTCTGCGACCGCGTGGGCGTGGCCAAGG
CCGACAGCTGGATCGACATGAGCACGCTCGAAGGCTCCGTGCGCGACGACCTGGACGCGCGCGCAGCGCGCGGCGTGGCC
GTGCTCGACCCGCTCAAGCTGATCCTCGACAACTACCCCGAAGGCCAGACCGAGGAATGCTCGGCGCCGGTGCATCCGAA
GAAGCCGGAATTGGGCAAGCGCGTGTTCCCGATCTCGCGCGAGCTGTGGATCGAGCGCGAGGACTTCAACGAGACCCCGC
CGAAGGGCTATTTCCGCCTGTTCCCGGGCAACAAGGTGCGCCTGAAGTACGGCTATGTGATCGAGTGCACCGGCGTGGAC
AAGGACGCTGACGGTAACGTCATCGCCGTGCACGCAAACTACCTTCCCGACACCAAGAGCGGCACGCCGGGCGCGGACAG
CGTCAAGGTCAAGGGCGTGATCCACTGGGTCAGCGCCGCCGCGGCCTACGAGTGCGAAGTGCGCCTGTACGACCGCTTGT
TCAACGACCCGAACCCGGATGCCGGCGGCAAGAACTTCCTCGAAGCGCTGAACCCCGATTCGAAGAAGGTAATCACCGCC
TATCTGGAGCCGAGCCTGCGTGACGCGAAGCCGGAAGACCGCTTCCAGTTCGAGCGCCATGGCTACTTCGTCGCCGACCG
CAACGATTCCCAGCCGGGCAAGCCGGTATTCAACCGCATCGTCGGGTTGAAAGACAGCTGGGGCAAGTGA

Upstream 100 bases:

>100_bases
TTCCGTGATCCCCACCACGCCAGCCGGGTGCCGCCATGGACAAAAGCGGGCACAAATCCAACGTGCTCCTGCCGAGTGGC
ACCGCTGGCACGGTAAAATC

Downstream 100 bases:

>100_bases
TGGCAAAGGCAGGCAAATCGAACGTGCAGGTCATCACGTTCGAGCTCGACGGCGAATTCATTGCGCTCAATGACCTGCTC
AAGCTGGCCGGCATATGCGA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MKLAIRHATLKTKRSIQPLAGATMSHDNKPTDSTPASPAVSNFLRSIIDQDLAAGTYAGRQDSQGEPLPTVITRFPPEPN
GYLHIGHAKSICLNFGLARDYGGRCHLRFDDTNPVKEDTEYVDSIIDAVHWLGFSWDSKTPGGQPHLHYASDYFDQLYAF
AEKLIERGAAYVDSQSAEQIAANRGNFSEPGKPSPFRDRSVEENLQLFRDMRDGKYKDGEHVLRAKIDMTAPNIVMRDPV
IYRIRHAHHHRTGDKWCIYPMYDFTHCISDAIENISHSLCTLEFENNRPLYDWVLEHLRDAGVFRDPLPHQYEFARLNLT
YAITSKRKLKQLVDEQRVDGWDDPRMPTIVGIRRRGYTPESIQLFCDRVGVAKADSWIDMSTLEGSVRDDLDARAARGVA
VLDPLKLILDNYPEGQTEECSAPVHPKKPELGKRVFPISRELWIEREDFNETPPKGYFRLFPGNKVRLKYGYVIECTGVD
KDADGNVIAVHANYLPDTKSGTPGADSVKVKGVIHWVSAAAAYECEVRLYDRLFNDPNPDAGGKNFLEALNPDSKKVITA
YLEPSLRDAKPEDRFQFERHGYFVADRNDSQPGKPVFNRIVGLKDSWGK

Sequences:

>Translated_609_residues
MKLAIRHATLKTKRSIQPLAGATMSHDNKPTDSTPASPAVSNFLRSIIDQDLAAGTYAGRQDSQGEPLPTVITRFPPEPN
GYLHIGHAKSICLNFGLARDYGGRCHLRFDDTNPVKEDTEYVDSIIDAVHWLGFSWDSKTPGGQPHLHYASDYFDQLYAF
AEKLIERGAAYVDSQSAEQIAANRGNFSEPGKPSPFRDRSVEENLQLFRDMRDGKYKDGEHVLRAKIDMTAPNIVMRDPV
IYRIRHAHHHRTGDKWCIYPMYDFTHCISDAIENISHSLCTLEFENNRPLYDWVLEHLRDAGVFRDPLPHQYEFARLNLT
YAITSKRKLKQLVDEQRVDGWDDPRMPTIVGIRRRGYTPESIQLFCDRVGVAKADSWIDMSTLEGSVRDDLDARAARGVA
VLDPLKLILDNYPEGQTEECSAPVHPKKPELGKRVFPISRELWIEREDFNETPPKGYFRLFPGNKVRLKYGYVIECTGVD
KDADGNVIAVHANYLPDTKSGTPGADSVKVKGVIHWVSAAAAYECEVRLYDRLFNDPNPDAGGKNFLEALNPDSKKVITA
YLEPSLRDAKPEDRFQFERHGYFVADRNDSQPGKPVFNRIVGLKDSWGK
>Mature_609_residues
MKLAIRHATLKTKRSIQPLAGATMSHDNKPTDSTPASPAVSNFLRSIIDQDLAAGTYAGRQDSQGEPLPTVITRFPPEPN
GYLHIGHAKSICLNFGLARDYGGRCHLRFDDTNPVKEDTEYVDSIIDAVHWLGFSWDSKTPGGQPHLHYASDYFDQLYAF
AEKLIERGAAYVDSQSAEQIAANRGNFSEPGKPSPFRDRSVEENLQLFRDMRDGKYKDGEHVLRAKIDMTAPNIVMRDPV
IYRIRHAHHHRTGDKWCIYPMYDFTHCISDAIENISHSLCTLEFENNRPLYDWVLEHLRDAGVFRDPLPHQYEFARLNLT
YAITSKRKLKQLVDEQRVDGWDDPRMPTIVGIRRRGYTPESIQLFCDRVGVAKADSWIDMSTLEGSVRDDLDARAARGVA
VLDPLKLILDNYPEGQTEECSAPVHPKKPELGKRVFPISRELWIEREDFNETPPKGYFRLFPGNKVRLKYGYVIECTGVD
KDADGNVIAVHANYLPDTKSGTPGADSVKVKGVIHWVSAAAAYECEVRLYDRLFNDPNPDAGGKNFLEALNPDSKKVITA
YLEPSLRDAKPEDRFQFERHGYFVADRNDSQPGKPVFNRIVGLKDSWGK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=546, Percent_Identity=46.7032967032967, Blast_Score=435, Evalue=1e-122,
Organism=Homo sapiens, GI62241042, Length=536, Percent_Identity=35.634328358209, Blast_Score=283, Evalue=4e-76,
Organism=Escherichia coli, GI1786895, Length=570, Percent_Identity=57.3684210526316, Blast_Score=663, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=314, Percent_Identity=23.5668789808917, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=547, Percent_Identity=43.327239488117, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17511007, Length=520, Percent_Identity=31.9230769230769, Blast_Score=241, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6324742, Length=579, Percent_Identity=42.832469775475, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321192, Length=530, Percent_Identity=35.0943396226415, Blast_Score=283, Evalue=5e-77,
Organism=Drosophila melanogaster, GI17864488, Length=547, Percent_Identity=42.2303473491773, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24649466, Length=528, Percent_Identity=33.1439393939394, Blast_Score=261, Evalue=7e-70,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 68962; Mature: 68962

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAIRHATLKTKRSIQPLAGATMSHDNKPTDSTPASPAVSNFLRSIIDQDLAAGTYAGR
CCEEEEHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
QDSQGEPLPTVITRFPPEPNGYLHIGHAKSICLNFGLARDYGGRCHLRFDDTNPVKEDTE
CCCCCCCCCHHHHCCCCCCCCEEEECCHHHHHHHCCHHCCCCCEEEEEECCCCCCHHHHH
YVDSIIDAVHWLGFSWDSKTPGGQPHLHYASDYFDQLYAFAEKLIERGAAYVDSQSAEQI
HHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHH
AANRGNFSEPGKPSPFRDRSVEENLQLFRDMRDGKYKDGEHVLRAKIDMTAPNIVMRDPV
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEECCCH
IYRIRHAHHHRTGDKWCIYPMYDFTHCISDAIENISHSLCTLEFENNRPLYDWVLEHLRD
HHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHH
AGVFRDPLPHQYEFARLNLTYAITSKRKLKQLVDEQRVDGWDDPRMPTIVGIRRRGYTPE
CCCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEHHHCCCCCH
SIQLFCDRVGVAKADSWIDMSTLEGSVRDDLDARAARGVAVLDPLKLILDNYPEGQTEEC
HHHHHHHHCCCCCCCCCEEHHHHCCCHHHCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
SAPVHPKKPELGKRVFPISRELWIEREDFNETPPKGYFRLFPGNKVRLKYGYVIECTGVD
CCCCCCCCCCCCCEECCCCHHHEEECCCCCCCCCCCEEEECCCCEEEEEEEEEEEECCCC
KDADGNVIAVHANYLPDTKSGTPGADSVKVKGVIHWVSAAAAYECEVRLYDRLFNDPNPD
CCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHEEHHHHHHHHCCCCCCC
AGGKNFLEALNPDSKKVITAYLEPSLRDAKPEDRFQFERHGYFVADRNDSQPGKPVFNRI
CCHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHH
VGLKDSWGK
HCCCCCCCC
>Mature Secondary Structure
MKLAIRHATLKTKRSIQPLAGATMSHDNKPTDSTPASPAVSNFLRSIIDQDLAAGTYAGR
CCEEEEHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
QDSQGEPLPTVITRFPPEPNGYLHIGHAKSICLNFGLARDYGGRCHLRFDDTNPVKEDTE
CCCCCCCCCHHHHCCCCCCCCEEEECCHHHHHHHCCHHCCCCCEEEEEECCCCCCHHHHH
YVDSIIDAVHWLGFSWDSKTPGGQPHLHYASDYFDQLYAFAEKLIERGAAYVDSQSAEQI
HHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHH
AANRGNFSEPGKPSPFRDRSVEENLQLFRDMRDGKYKDGEHVLRAKIDMTAPNIVMRDPV
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEECCCH
IYRIRHAHHHRTGDKWCIYPMYDFTHCISDAIENISHSLCTLEFENNRPLYDWVLEHLRD
HHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHH
AGVFRDPLPHQYEFARLNLTYAITSKRKLKQLVDEQRVDGWDDPRMPTIVGIRRRGYTPE
CCCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEHHHCCCCCH
SIQLFCDRVGVAKADSWIDMSTLEGSVRDDLDARAARGVAVLDPLKLILDNYPEGQTEEC
HHHHHHHHCCCCCCCCCEEHHHHCCCHHHCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
SAPVHPKKPELGKRVFPISRELWIEREDFNETPPKGYFRLFPGNKVRLKYGYVIECTGVD
CCCCCCCCCCCCCEECCCCHHHEEECCCCCCCCCCCEEEECCCCEEEEEEEEEEEECCCC
KDADGNVIAVHANYLPDTKSGTPGADSVKVKGVIHWVSAAAAYECEVRLYDRLFNDPNPD
CCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHEEHHHHHHHHCCCCCCC
AGGKNFLEALNPDSKKVITAYLEPSLRDAKPEDRFQFERHGYFVADRNDSQPGKPVFNRI
CCHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHH
VGLKDSWGK
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA