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The map label for this gene is phnA [H]

Identifier: 73539696

GI number: 73539696

Start: 2717220

End: 2718455

Strand: Direct

Name: phnA [H]

Synonym: Reut_B5876

Alternate gene names: 73539696

Gene position: 2717220-2718455 (Clockwise)

Preceding gene: 73539695

Following gene: 73539697

Centisome position: 99.67

GC content: 65.7

Gene sequence:

>1236_bases
ATGGGAACGACCAAGGCTGAACGCATTGAAGTCAACGGCAGGACCTACCGCTGGATGAACCGCCCGGTGGTCGTGGTATG
CGTCGACGGCTGCGCACCAGAATATCTGCACGCGGCCACGGAAGCGGGCGTGGCACCTTTCCTGCGGACCGTCATGCAGC
ACGGCACGAGCCTGCTGGGCGACTGCGTGATTCCCTCGTTCACCAACCCCAACAACCTGTCCATCGTCACAGGGGCGCCG
CCGTCGGTCCACGGCATCTGCGGCAACTATTTCTTCGATCGGGAACTGGGCGCCGAAGTGATGATGAATGATCCCAAGTA
CCTGCGCGCCGGCACCGTGCTCGCGGCCTTCGCGAACGCCGGGGCGAAAGTGGCTGTGGTCACGGCCAAGGACAAGCTGC
GCAAGCTGCTCGGCCATGGCATGACGGGAATCTGCTTCTCGTCGGAGAAGGCTGACCAGGTCACGCAGGAGGAAAACGGC
ATCACCGGCGTCGTGGAGATGGTGGGCATGCCGGTGCCGTCGGTCTACAGTGCGGCGCTGTCAGAGTTCGTCTTCGCGGC
CGGCGTCAAGCTGATGGAGCGCGAGCGGCCCGACCTGATGTACCTGTCCACCACGGACTACGTACAACACAAGGCGGCTC
CGGGCAGCCCGGCCGCCAACGCCTTCTACCAGATGATGGACGGCTACCTGAGCCAGCTCGACGCGCTTGGCGCCACGATC
GTGCTGACTGCCGACCACGGCATGAACGACAAGCACGGCGCCACCGGCGAGCCCAACGTCATCTACCTGCAGGACCAGCT
CGACAGCTGGTACGGCGAGGGCGCGGCCCGCGTGATCCTGCCCATTACCGATCCCTACGTGGTCCACCACGGCGCGCTGG
GCTCGTTCGCGACCATCTATACGCCGGACGCCGAGAGCGCCGCCCGCTGGATTTCGCGGATCGCCGACATCGACGGCATG
GAAAGCGTGCTGACCCGCCAGGAGGCCGCGGAGCGCTTCGGGCTGCCGCCAGACCGCATCGGCGACATCGTCGCGGTATC
GCGGCAGAACGTCGTGATCGGCACATCGAAGTCCAGGCATGACCTGTCCGGACTTGACGCACCGCTGCGCTCCCACGGCG
GGGTGTCCGAGCAAGTCGTGCCGCTGCTCTGCAATCGTTCAATGGTCGGCCTGCAGCCGGACCGCCGCCTGCGCAACTTC
GACGCACTCGACCTCGCGTTGAATCACGCCGCCTGA

Upstream 100 bases:

>100_bases
TGGCCGCCAGCCGCGTACGCATGCTCAAGGCGCACCGCAAGGTGCATCCGGAAAGCAACAACGAACCATGAGCTGACGCT
CATCACCAAGGGGATTGGAA

Downstream 100 bases:

>100_bases
CGGCGGCTTCCAGCCTACCTGCCTGCTGTCCTGATACGCCCCTTGCGCAGGGGCGGGGGGACAGTCGCGCCTGCCGAACG
AGATCAACAGGAGACAAACA

Product: Type I phosphodiesterase/nucleotide pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MGTTKAERIEVNGRTYRWMNRPVVVVCVDGCAPEYLHAATEAGVAPFLRTVMQHGTSLLGDCVIPSFTNPNNLSIVTGAP
PSVHGICGNYFFDRELGAEVMMNDPKYLRAGTVLAAFANAGAKVAVVTAKDKLRKLLGHGMTGICFSSEKADQVTQEENG
ITGVVEMVGMPVPSVYSAALSEFVFAAGVKLMERERPDLMYLSTTDYVQHKAAPGSPAANAFYQMMDGYLSQLDALGATI
VLTADHGMNDKHGATGEPNVIYLQDQLDSWYGEGAARVILPITDPYVVHHGALGSFATIYTPDAESAARWISRIADIDGM
ESVLTRQEAAERFGLPPDRIGDIVAVSRQNVVIGTSKSRHDLSGLDAPLRSHGGVSEQVVPLLCNRSMVGLQPDRRLRNF
DALDLALNHAA

Sequences:

>Translated_411_residues
MGTTKAERIEVNGRTYRWMNRPVVVVCVDGCAPEYLHAATEAGVAPFLRTVMQHGTSLLGDCVIPSFTNPNNLSIVTGAP
PSVHGICGNYFFDRELGAEVMMNDPKYLRAGTVLAAFANAGAKVAVVTAKDKLRKLLGHGMTGICFSSEKADQVTQEENG
ITGVVEMVGMPVPSVYSAALSEFVFAAGVKLMERERPDLMYLSTTDYVQHKAAPGSPAANAFYQMMDGYLSQLDALGATI
VLTADHGMNDKHGATGEPNVIYLQDQLDSWYGEGAARVILPITDPYVVHHGALGSFATIYTPDAESAARWISRIADIDGM
ESVLTRQEAAERFGLPPDRIGDIVAVSRQNVVIGTSKSRHDLSGLDAPLRSHGGVSEQVVPLLCNRSMVGLQPDRRLRNF
DALDLALNHAA
>Mature_410_residues
GTTKAERIEVNGRTYRWMNRPVVVVCVDGCAPEYLHAATEAGVAPFLRTVMQHGTSLLGDCVIPSFTNPNNLSIVTGAPP
SVHGICGNYFFDRELGAEVMMNDPKYLRAGTVLAAFANAGAKVAVVTAKDKLRKLLGHGMTGICFSSEKADQVTQEENGI
TGVVEMVGMPVPSVYSAALSEFVFAAGVKLMERERPDLMYLSTTDYVQHKAAPGSPAANAFYQMMDGYLSQLDALGATIV
LTADHGMNDKHGATGEPNVIYLQDQLDSWYGEGAARVILPITDPYVVHHGALGSFATIYTPDAESAARWISRIADIDGME
SVLTRQEAAERFGLPPDRIGDIVAVSRQNVVIGTSKSRHDLSGLDAPLRSHGGVSEQVVPLLCNRSMVGLQPDRRLRNFD
ALDLALNHAA

Specific function: Specifically hydrolyzes phosphonoacetate. Does not have activity on other organophosphonates or acetates [H]

COG id: COG1524

COG function: function code R; Uncharacterized proteins of the AP superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkaline phosphatase family. PhnA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR002591
- InterPro:   IPR012710
- InterPro:   IPR023116 [H]

Pfam domain/function: PF01663 Phosphodiest [H]

EC number: =3.11.1.2 [H]

Molecular weight: Translated: 44205; Mature: 44074

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTKAERIEVNGRTYRWMNRPVVVVCVDGCAPEYLHAATEAGVAPFLRTVMQHGTSLLG
CCCCCCCEEEECCCEEEEECCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHCHHHHH
DCVIPSFTNPNNLSIVTGAPPSVHGICGNYFFDRELGAEVMMNDPKYLRAGTVLAAFANA
HCCCCCCCCCCCEEEEECCCCCCHHHHCCEEECHHCCCCEEECCCCHHHHHHHHHHHHCC
GAKVAVVTAKDKLRKLLGHGMTGICFSSEKADQVTQEENGITGVVEMVGMPVPSVYSAAL
CCEEEEEECHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHH
SEFVFAAGVKLMERERPDLMYLSTTDYVQHKAAPGSPAANAFYQMMDGYLSQLDALGATI
HHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEE
VLTADHGMNDKHGATGEPNVIYLQDQLDSWYGEGAARVILPITDPYVVHHGALGSFATIY
EEEECCCCCCCCCCCCCCCEEEEECCHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TPDAESAARWISRIADIDGMESVLTRQEAAERFGLPPDRIGDIVAVSRQNVVIGTSKSRH
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCEEEECCCCEEEECCCCCC
DLSGLDAPLRSHGGVSEQVVPLLCNRSMVGLQPDRRLRNFDALDLALNHAA
CCCCCCCCHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure 
GTTKAERIEVNGRTYRWMNRPVVVVCVDGCAPEYLHAATEAGVAPFLRTVMQHGTSLLG
CCCCCCEEEECCCEEEEECCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHCHHHHH
DCVIPSFTNPNNLSIVTGAPPSVHGICGNYFFDRELGAEVMMNDPKYLRAGTVLAAFANA
HCCCCCCCCCCCEEEEECCCCCCHHHHCCEEECHHCCCCEEECCCCHHHHHHHHHHHHCC
GAKVAVVTAKDKLRKLLGHGMTGICFSSEKADQVTQEENGITGVVEMVGMPVPSVYSAAL
CCEEEEEECHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHH
SEFVFAAGVKLMERERPDLMYLSTTDYVQHKAAPGSPAANAFYQMMDGYLSQLDALGATI
HHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEE
VLTADHGMNDKHGATGEPNVIYLQDQLDSWYGEGAARVILPITDPYVVHHGALGSFATIY
EEEECCCCCCCCCCCCCCCEEEEECCHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TPDAESAARWISRIADIDGMESVLTRQEAAERFGLPPDRIGDIVAVSRQNVVIGTSKSRH
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCEEEECCCCEEEECCCCCC
DLSGLDAPLRSHGGVSEQVVPLLCNRSMVGLQPDRRLRNFDALDLALNHAA
CCCCCCCCHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA