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The map label for this gene is proA [H]

Identifier: 73539592

GI number: 73539592

Start: 2597108

End: 2597782

Strand: Reverse

Name: proA [H]

Synonym: Reut_B5772

Alternate gene names: 73539592

Gene position: 2597782-2597108 (Counterclockwise)

Preceding gene: 73539593

Following gene: 73539591

Centisome position: 95.29

GC content: 67.7

Gene sequence:

>675_bases
ATGACATTGTCCATCGACCGCATCGATCCGCGCGACACCACGCAACTGGATTTCGCGCGTACCGCTCCGCAGATCGTTGA
CGCCGCCCGTGCCGTCCCAACGGCCACGCTGCACGAGGCCGGCGGGAAGATCGGAGCGTTTCCGTCCGCGATCAAACCCG
TCGCACCGGGATTCAGGCTGTGCGGCCCCGCCGTCACAGTGCATGCGCCGGGCGGCGACAACCTGTGGCTGCACCGCGCC
ATCTATGCCGCGCAACCAGGCGACGTGCTGGTGGTGTCGGTCAGCGACGCTTTCGAGCACGGCTACTGGGGGGAGGTCAT
GTCCACCGCCAGCCAGGTGCGCGGCCTCGCCGGCCTGGTCATCGACGGCTGCGTGCGTGATGGCGTGCTGCTGGAAGAGA
TCGGCTTCCCGGTGTTCGCCCGCGGACTTTGCATCCGCGGCACCGGCAAGGATTTCGGCGCGCGCGGCTGGATCAATGCA
CCGACCGTGTTTGGCAACGTCACCGTCCATGCTGGCGACCTGATCGTCGGCGACGGCGACGGCGTGGTCTGCATTCCGCG
CGACAGTGCGGGCAAGGTGGTGGACGCCGGCCTTGCGCGAGAAGTGAACGAGGCTGATCAGTGCCGCCGACTCCGTGCAG
GCGAGGCCACGCTCGACATCTTTGGCTGGCGCTGA

Upstream 100 bases:

>100_bases
ACGCCATTCGCAAGGCAGTCGCCGGCGGCATGCGTCTGGACGAGGCCCGCGCCGAGTACCGCTACCATCAACTGCAGACG
CGCGCCGAAGGAGCGAAAGC

Downstream 100 bases:

>100_bases
GGAAGGAGGCAGACGACATGAAGGAAAGCATCGACGACAAGACGACGATCCGCACGAGCTGGATCGACATCCCCGCAGCC
GATGGTCGCGCGTACCAAGG

Product: dimethylmenaquinone methyltransferase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTLSIDRIDPRDTTQLDFARTAPQIVDAARAVPTATLHEAGGKIGAFPSAIKPVAPGFRLCGPAVTVHAPGGDNLWLHRA
IYAAQPGDVLVVSVSDAFEHGYWGEVMSTASQVRGLAGLVIDGCVRDGVLLEEIGFPVFARGLCIRGTGKDFGARGWINA
PTVFGNVTVHAGDLIVGDGDGVVCIPRDSAGKVVDAGLAREVNEADQCRRLRAGEATLDIFGWR

Sequences:

>Translated_224_residues
MTLSIDRIDPRDTTQLDFARTAPQIVDAARAVPTATLHEAGGKIGAFPSAIKPVAPGFRLCGPAVTVHAPGGDNLWLHRA
IYAAQPGDVLVVSVSDAFEHGYWGEVMSTASQVRGLAGLVIDGCVRDGVLLEEIGFPVFARGLCIRGTGKDFGARGWINA
PTVFGNVTVHAGDLIVGDGDGVVCIPRDSAGKVVDAGLAREVNEADQCRRLRAGEATLDIFGWR
>Mature_223_residues
TLSIDRIDPRDTTQLDFARTAPQIVDAARAVPTATLHEAGGKIGAFPSAIKPVAPGFRLCGPAVTVHAPGGDNLWLHRAI
YAAQPGDVLVVSVSDAFEHGYWGEVMSTASQVRGLAGLVIDGCVRDGVLLEEIGFPVFARGLCIRGTGKDFGARGWINAP
TVFGNVTVHAGDLIVGDGDGVVCIPRDSAGKVVDAGLAREVNEADQCRRLRAGEATLDIFGWR

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 23541; Mature: 23410

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSIDRIDPRDTTQLDFARTAPQIVDAARAVPTATLHEAGGKIGAFPSAIKPVAPGFRL
CEEECCCCCCCCCCEEHHHHHCHHHHHHHHHCCCHHHHHCCCCCCCCCCHHCCCCCCCEE
CGPAVTVHAPGGDNLWLHRAIYAAQPGDVLVVSVSDAFEHGYWGEVMSTASQVRGLAGLV
CCCEEEEECCCCCCEEEEEEEEECCCCCEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHH
IDGCVRDGVLLEEIGFPVFARGLCIRGTGKDFGARGWINAPTVFGNVTVHAGDLIVGDGD
HHHHHCCCEEHHHHCCCHHHCCEEEECCCCCCCCCCCCCCCEEEEEEEEEECCEEEECCC
GVVCIPRDSAGKVVDAGLAREVNEADQCRRLRAGEATLDIFGWR
CEEEEECCCCCCEEHHHHHHHCCHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure 
TLSIDRIDPRDTTQLDFARTAPQIVDAARAVPTATLHEAGGKIGAFPSAIKPVAPGFRL
EEECCCCCCCCCCEEHHHHHCHHHHHHHHHCCCHHHHHCCCCCCCCCCHHCCCCCCCEE
CGPAVTVHAPGGDNLWLHRAIYAAQPGDVLVVSVSDAFEHGYWGEVMSTASQVRGLAGLV
CCCEEEEECCCCCCEEEEEEEEECCCCCEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHH
IDGCVRDGVLLEEIGFPVFARGLCIRGTGKDFGARGWINAPTVFGNVTVHAGDLIVGDGD
HHHHHCCCEEHHHHCCCHHHCCEEEECCCCCCCCCCCCCCCEEEEEEEEEECCEEEECCC
GVVCIPRDSAGKVVDAGLAREVNEADQCRRLRAGEATLDIFGWR
CEEEEECCCCCCEEHHHHHHHCCHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]