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The map label for this gene is gbh [H]

Identifier: 73539527

GI number: 73539527

Start: 2532753

End: 2533727

Strand: Reverse

Name: gbh [H]

Synonym: Reut_B5705

Alternate gene names: 73539527

Gene position: 2533727-2532753 (Counterclockwise)

Preceding gene: 73539531

Following gene: 73539526

Centisome position: 92.94

GC content: 54.87

Gene sequence:

>975_bases
ATGGAAGAAAAAATGTTTGCGCCGGTCACCGGTACAGTGACGCCACGTTATGCCGGTTTGGCTACATTGATGCGGCTGCC
GCACATCGAACTGATGAGCGAGAACATTCCAGATGTGGATATCGGGTTGATTGGGGTGCCATGGGATGGTGGTACCACCA
ATCGTCCGGGCGCCCGACATGGCCCTCGTCAGGTGCGTGATATCTCGACGATGGTGCGCAATGTCAACCGAAGCAGCGGT
ATCAAACCATTTGAGATCTGCAATTGCGCGGACCTAGGGGATACGCCTGTCAATCCGGTGGATTTGATCGATTCGATGAA
TCGCATCACCGCGTTCTACGACGCAGTGTGCAGGGCTAATATAGCGCCACTATCGGTGGGTGGAGATCACCTGGTAACGT
TGCCGATCTTGCGGGCGCTTGCAACGGACGGGCCCGTTGGTATGGTTCACTTTGACGCGCATACAGATACGTGGAATCGC
TATTTTGGCGATAACCTTTACACACATGGCACCCCCTTTCGGCGAGCGATCGAAGAGGGATTGCTGGATCCGAAACGGAC
CATACAAATCGGTATTCGCGGGGCGTTGTACAACGACAGTGAGAATGATTGGGGAGAACGTCAGGGCATTCGAGTCATCG
ACATGGATGAATTTCGGTCGATGGGTGTCGAAGCCGTGATCCAGGAAGCCTGGCGTGTAGTTGGAAACGGCCGCACGTAT
GTGACCTTCGATGTCGATGCACTGGATCCCGTATACGCCCCCGGCACTGGCACACCGGAAATCGGTGGGCTGACAACGAT
CGAGGCCCAGCACATGATTCGTGGACTACGGGGCCTGAATCTCATCGGAGGTGACGTGGTTGAAGTGTCGCCGCCGTTTG
ATCCAACTGGCAATACGGCATTGGTCGCTGCCACGTTGATGTTCGAGATTCTATGTGTTCTAGCTGCCAACATCAGCAAG
CAAAAACGCCGCTAG

Upstream 100 bases:

>100_bases
TGTCACTCGCGTGCAAGACTAAATGGACGCCTATGGCGGATGGCCGGACCACAGCATCGGAGCGCCGGTTCCAATCGTAC
TAACTGCGAGGACCTTACTC

Downstream 100 bases:

>100_bases
CCTCCGAACATCTAGTCAGCGCCCAAAGAAATAGACTGCCAGCCGTCGACTGAGATCGACAGCTAGGTAAGCCTCTACGC
AGGAGACAAAAATGGACACT

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MEEKMFAPVTGTVTPRYAGLATLMRLPHIELMSENIPDVDIGLIGVPWDGGTTNRPGARHGPRQVRDISTMVRNVNRSSG
IKPFEICNCADLGDTPVNPVDLIDSMNRITAFYDAVCRANIAPLSVGGDHLVTLPILRALATDGPVGMVHFDAHTDTWNR
YFGDNLYTHGTPFRRAIEEGLLDPKRTIQIGIRGALYNDSENDWGERQGIRVIDMDEFRSMGVEAVIQEAWRVVGNGRTY
VTFDVDALDPVYAPGTGTPEIGGLTTIEAQHMIRGLRGLNLIGGDVVEVSPPFDPTGNTALVAATLMFEILCVLAANISK
QKRR

Sequences:

>Translated_324_residues
MEEKMFAPVTGTVTPRYAGLATLMRLPHIELMSENIPDVDIGLIGVPWDGGTTNRPGARHGPRQVRDISTMVRNVNRSSG
IKPFEICNCADLGDTPVNPVDLIDSMNRITAFYDAVCRANIAPLSVGGDHLVTLPILRALATDGPVGMVHFDAHTDTWNR
YFGDNLYTHGTPFRRAIEEGLLDPKRTIQIGIRGALYNDSENDWGERQGIRVIDMDEFRSMGVEAVIQEAWRVVGNGRTY
VTFDVDALDPVYAPGTGTPEIGGLTTIEAQHMIRGLRGLNLIGGDVVEVSPPFDPTGNTALVAATLMFEILCVLAANISK
QKRR
>Mature_324_residues
MEEKMFAPVTGTVTPRYAGLATLMRLPHIELMSENIPDVDIGLIGVPWDGGTTNRPGARHGPRQVRDISTMVRNVNRSSG
IKPFEICNCADLGDTPVNPVDLIDSMNRITAFYDAVCRANIAPLSVGGDHLVTLPILRALATDGPVGMVHFDAHTDTWNR
YFGDNLYTHGTPFRRAIEEGLLDPKRTIQIGIRGALYNDSENDWGERQGIRVIDMDEFRSMGVEAVIQEAWRVVGNGRTY
VTFDVDALDPVYAPGTGTPEIGGLTTIEAQHMIRGLRGLNLIGGDVVEVSPPFDPTGNTALVAATLMFEILCVLAANISK
QKRR

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=300, Percent_Identity=49.3333333333333, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI4502215, Length=306, Percent_Identity=23.8562091503268, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI10947139, Length=281, Percent_Identity=25.9786476868327, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1789306, Length=283, Percent_Identity=42.4028268551237, Blast_Score=184, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI71996843, Length=195, Percent_Identity=29.2307692307692, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325146, Length=205, Percent_Identity=33.6585365853659, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24638886, Length=289, Percent_Identity=26.643598615917, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 35409; Mature: 35409

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKMFAPVTGTVTPRYAGLATLMRLPHIELMSENIPDVDIGLIGVPWDGGTTNRPGARH
CCCCEECCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCC
GPRQVRDISTMVRNVNRSSGIKPFEICNCADLGDTPVNPVDLIDSMNRITAFYDAVCRAN
CHHHHHHHHHHHHHHHHHCCCCHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
IAPLSVGGDHLVTLPILRALATDGPVGMVHFDAHTDTWNRYFGDNLYTHGTPFRRAIEEG
CCEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHH
LLDPKRTIQIGIRGALYNDSENDWGERQGIRVIDMDEFRSMGVEAVIQEAWRVVGNGRTY
CCCCCCEEEEEEEEEEECCCCCCCHHHCCCEEEEHHHHHHCCHHHHHHHHHHHHCCCCEE
VTFDVDALDPVYAPGTGTPEIGGLTTIEAQHMIRGLRGLNLIGGDVVEVSPPFDPTGNTA
EEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCEECCCCEEEECCCCCCCCCHH
LVAATLMFEILCVLAANISKQKRR
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEEKMFAPVTGTVTPRYAGLATLMRLPHIELMSENIPDVDIGLIGVPWDGGTTNRPGARH
CCCCEECCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCC
GPRQVRDISTMVRNVNRSSGIKPFEICNCADLGDTPVNPVDLIDSMNRITAFYDAVCRAN
CHHHHHHHHHHHHHHHHHCCCCHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
IAPLSVGGDHLVTLPILRALATDGPVGMVHFDAHTDTWNRYFGDNLYTHGTPFRRAIEEG
CCEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHH
LLDPKRTIQIGIRGALYNDSENDWGERQGIRVIDMDEFRSMGVEAVIQEAWRVVGNGRTY
CCCCCCEEEEEEEEEEECCCCCCCHHHCCCEEEEHHHHHHCCHHHHHHHHHHHHCCCCEE
VTFDVDALDPVYAPGTGTPEIGGLTTIEAQHMIRGLRGLNLIGGDVVEVSPPFDPTGNTA
EEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCEECCCCEEEECCCCCCCCCHH
LVAATLMFEILCVLAANISKQKRR
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA