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The map label for this gene is yxlA [H]

Identifier: 73539526

GI number: 73539526

Start: 2531189

End: 2532661

Strand: Reverse

Name: yxlA [H]

Synonym: Reut_B5704

Alternate gene names: 73539526

Gene position: 2532661-2531189 (Counterclockwise)

Preceding gene: 73539527

Following gene: 73539522

Centisome position: 92.9

GC content: 57.84

Gene sequence:

>1473_bases
ATGGACACTTCGAAATTCGGCACAGAATCCTCGGCAATCTCACCTTCAGGGCCGAACCTAACCTCAGGTCAGATCTCCTC
CCGGCTCATTGAACGCCGCTCGATTGACTTTATCCCAGAATCGGAAAGGCATGGCAGCCTGGCCAGTCAGTTTACTTTAT
GGCTTGGCGCCAATCTTCAGATCACCGCTGTGGTAACGGGTGCACTGGCAGTGGTGCTTGGCGGCGACGTGTTCTGGTCC
CTCATCGGCCTCCTGATTGGCCAGATCCTAGGTGGTGCAGTCATGGCGCTCCATGGCGCGCAAGGACCTCAGCTCGGGCT
CCCGCAGATGATCTCCAGTCGAGTCCAGTTTGGCGTCTACGGTGCGATTGTGCCCCTGGTGCTTGTCTGTATCATGTACG
TGGGATTCTCTGCGGGGGGCATGGTTCTGTCCGGCCAAGCGCTCAGCCATCTGATGGGCATAAGCAACGCCAGCTCGATT
CTACTGTTCTCGGGCCTGGTGATCATGCTCGCGACATTCGGCTATCGCACCATTCATTTCATGGGGCGAGTCTCCAGCGT
GATTGGCGTTGTGGCGTTCCTGTACCTGTTCGCCAGCCTACTCAAAGGGCAGGACGTTGGCGCGTTGCTGCAGAATCGCA
GCTTCGATGTGGGGCACTTCCTGCTGGCCGTTTCCCTTTCCGCCTCATGGCAGATTGCCTACGGGCCATATGTCGCCGAC
TACTCGCGCTATCTGCCTCGCTCGACCTCGGCTTTCAAGACATTCCTCGCAGTGGGCATTGGTTCGGTGCTGGGTTCGCA
GATCTCCATGGTCTTCGGAGTCTTTGCCGCAGCGTTGGCGGGCAACCAGTTCGCCGGACATGAGGTGAGCTTCATCGTCG
ACTTGGGCGCGACTGGGGTAGCTGCCATTTTGCTCTACCTGACGATCGTCTTGGGCAAACTCACGATCACCACGTTGAAT
GCCTATGGGAGCGTCATGTCGGTCGCCGCCATCCTGACCGGACTTGGTGGGCAACGGACCATCTCCGGCCGTACGAAATT
CTTCTTCGTCGTGGTCATGGTTGGGTTTTCGACCGGGCTCGCTTTGGCGGCCGGGGAGCATGATTTTCTCAAGAAGTTCT
CAGCCTTCCTGTTGTTCCTGCTTGCGTTCCTGACTCCTTGGAGCGCCATCAACCTCGTCGACTACTACTTTGTCACCAAG
GAGCGCTACGACGTGCCAGCGCTCTTCAACCCCAACGGCCGCTATGGTCGCTGGAATGCCAGGGGCATGACGGTCTATGT
GTTGGGTGTAGCGGTGCAAATGCCCTTCATTGCTACCAGTTTCTACACCGGTGCATGGGTGGAGGCGCTCGGTGGTGTCG
ACATATCCTGGATTGTAGGTCTGGTTGTTCCAGCCGTGATTTACTACCACTTTGCCAGTAAAGCGAACGTGCCGCAGGCT
CTGATCCTGCCAGCCGACCACGCCGAGTCGTAG

Upstream 100 bases:

>100_bases
CGCCGCTAGCCTCCGAACATCTAGTCAGCGCCCAAAGAAATAGACTGCCAGCCGTCGACTGAGATCGACAGCTAGGTAAG
CCTCTACGCAGGAGACAAAA

Downstream 100 bases:

>100_bases
TCCGGCCAATCCGGCCTGCACCCGCGCGGTATCGGGTCGGTGCGCCTAGGTTACCCCCATCATGTCCGGAATGCCCTCGA
GAGCCCCGATTGCTACCGCG

Product: cytosine/purines, uracil, thiamine, allantoin permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MDTSKFGTESSAISPSGPNLTSGQISSRLIERRSIDFIPESERHGSLASQFTLWLGANLQITAVVTGALAVVLGGDVFWS
LIGLLIGQILGGAVMALHGAQGPQLGLPQMISSRVQFGVYGAIVPLVLVCIMYVGFSAGGMVLSGQALSHLMGISNASSI
LLFSGLVIMLATFGYRTIHFMGRVSSVIGVVAFLYLFASLLKGQDVGALLQNRSFDVGHFLLAVSLSASWQIAYGPYVAD
YSRYLPRSTSAFKTFLAVGIGSVLGSQISMVFGVFAAALAGNQFAGHEVSFIVDLGATGVAAILLYLTIVLGKLTITTLN
AYGSVMSVAAILTGLGGQRTISGRTKFFFVVVMVGFSTGLALAAGEHDFLKKFSAFLLFLLAFLTPWSAINLVDYYFVTK
ERYDVPALFNPNGRYGRWNARGMTVYVLGVAVQMPFIATSFYTGAWVEALGGVDISWIVGLVVPAVIYYHFASKANVPQA
LILPADHAES

Sequences:

>Translated_490_residues
MDTSKFGTESSAISPSGPNLTSGQISSRLIERRSIDFIPESERHGSLASQFTLWLGANLQITAVVTGALAVVLGGDVFWS
LIGLLIGQILGGAVMALHGAQGPQLGLPQMISSRVQFGVYGAIVPLVLVCIMYVGFSAGGMVLSGQALSHLMGISNASSI
LLFSGLVIMLATFGYRTIHFMGRVSSVIGVVAFLYLFASLLKGQDVGALLQNRSFDVGHFLLAVSLSASWQIAYGPYVAD
YSRYLPRSTSAFKTFLAVGIGSVLGSQISMVFGVFAAALAGNQFAGHEVSFIVDLGATGVAAILLYLTIVLGKLTITTLN
AYGSVMSVAAILTGLGGQRTISGRTKFFFVVVMVGFSTGLALAAGEHDFLKKFSAFLLFLLAFLTPWSAINLVDYYFVTK
ERYDVPALFNPNGRYGRWNARGMTVYVLGVAVQMPFIATSFYTGAWVEALGGVDISWIVGLVVPAVIYYHFASKANVPQA
LILPADHAES
>Mature_490_residues
MDTSKFGTESSAISPSGPNLTSGQISSRLIERRSIDFIPESERHGSLASQFTLWLGANLQITAVVTGALAVVLGGDVFWS
LIGLLIGQILGGAVMALHGAQGPQLGLPQMISSRVQFGVYGAIVPLVLVCIMYVGFSAGGMVLSGQALSHLMGISNASSI
LLFSGLVIMLATFGYRTIHFMGRVSSVIGVVAFLYLFASLLKGQDVGALLQNRSFDVGHFLLAVSLSASWQIAYGPYVAD
YSRYLPRSTSAFKTFLAVGIGSVLGSQISMVFGVFAAALAGNQFAGHEVSFIVDLGATGVAAILLYLTIVLGKLTITTLN
AYGSVMSVAAILTGLGGQRTISGRTKFFFVVVMVGFSTGLALAAGEHDFLKKFSAFLLFLLAFLTPWSAINLVDYYFVTK
ERYDVPALFNPNGRYGRWNARGMTVYVLGVAVQMPFIATSFYTGAWVEALGGVDISWIVGLVVPAVIYYHFASKANVPQA
LILPADHAES

Specific function: Transport Of Allantoin (By Similarity). [C]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320903, Length=263, Percent_Identity=27.7566539923954, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320897, Length=263, Percent_Identity=26.615969581749, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 51991; Mature: 51991

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSKFGTESSAISPSGPNLTSGQISSRLIERRSIDFIPESERHGSLASQFTLWLGANLQ
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHEEECCCEE
ITAVVTGALAVVLGGDVFWSLIGLLIGQILGGAVMALHGAQGPQLGLPQMISSRVQFGVY
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCHHHHHHHHHHHHH
GAIVPLVLVCIMYVGFSAGGMVLSGQALSHLMGISNASSILLFSGLVIMLATFGYRTIHF
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MGRVSSVIGVVAFLYLFASLLKGQDVGALLQNRSFDVGHFLLAVSLSASWQIAYGPYVAD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHEEECCCEEEEECCHHHH
YSRYLPRSTSAFKTFLAVGIGSVLGSQISMVFGVFAAALAGNQFAGHEVSFIVDLGATGV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHH
AAILLYLTIVLGKLTITTLNAYGSVMSVAAILTGLGGQRTISGRTKFFFVVVMVGFSTGL
HHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCC
ALAAGEHDFLKKFSAFLLFLLAFLTPWSAINLVDYYFVTKERYDVPALFNPNGRYGRWNA
EEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCCEECCCCCCCCCCC
RGMTVYVLGVAVQMPFIATSFYTGAWVEALGGVDISWIVGLVVPAVIYYHFASKANVPQA
CCEEEEEEEHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCE
LILPADHAES
EEECCCCCCC
>Mature Secondary Structure
MDTSKFGTESSAISPSGPNLTSGQISSRLIERRSIDFIPESERHGSLASQFTLWLGANLQ
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHEEECCCEE
ITAVVTGALAVVLGGDVFWSLIGLLIGQILGGAVMALHGAQGPQLGLPQMISSRVQFGVY
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCHHHHHHHHHHHHH
GAIVPLVLVCIMYVGFSAGGMVLSGQALSHLMGISNASSILLFSGLVIMLATFGYRTIHF
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MGRVSSVIGVVAFLYLFASLLKGQDVGALLQNRSFDVGHFLLAVSLSASWQIAYGPYVAD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHEEECCCEEEEECCHHHH
YSRYLPRSTSAFKTFLAVGIGSVLGSQISMVFGVFAAALAGNQFAGHEVSFIVDLGATGV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHH
AAILLYLTIVLGKLTITTLNAYGSVMSVAAILTGLGGQRTISGRTKFFFVVVMVGFSTGL
HHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCC
ALAAGEHDFLKKFSAFLLFLLAFLTPWSAINLVDYYFVTKERYDVPALFNPNGRYGRWNA
EEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCCEECCCCCCCCCCC
RGMTVYVLGVAVQMPFIATSFYTGAWVEALGGVDISWIVGLVVPAVIYYHFASKANVPQA
CCEEEEEEEHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCE
LILPADHAES
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]