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The map label for this gene is xylR [H]

Identifier: 73539495

GI number: 73539495

Start: 2505787

End: 2507565

Strand: Reverse

Name: xylR [H]

Synonym: Reut_B5673

Alternate gene names: 73539495

Gene position: 2507565-2505787 (Counterclockwise)

Preceding gene: 73539496

Following gene: 73539493

Centisome position: 91.98

GC content: 63.97

Gene sequence:

>1779_bases
ATGGCGAAGAGGCATCCCGGAAAACCCAAGTCCGGCTCACCGGCGCAAGGCCATCCCGGCCGGAATCAGAAGCGCGAGTC
CCCCGAGGCAATCCGGGTGCCGGCGATCCACGACCTCGCCAAGCGCCTGCGCTTCGCGCCGCAACAGGGTCGCATCTGGT
TGGACGACCAACGCATGATGCTAATGCACATCAGCTCTCTTGGCGCCTTGCGGCAAGAACTGATCGAAAGCCTTGGCAAG
GAAACAGCGCGCGGACTGATCACCCGTATCGGCTACCAGGCCGGCACGCGGGACGCAGCGATGGCGCGCAAGGTCCGCGC
CGGCCTGAACACCTATGACGACTTCCTGGCCGGTCCACAACTGGTCTCGCTGGAGGGTATGGTGCATTGCGAACCGGTGG
CGCTGGACATCGATGTCCAGCGTGGCCACTACTTCGGCGATTTTTATCTGGTGGACAGCTCCGAGGCGGAAGCCCACATC
GCCGGCTATGGTATCGGCAATGAATCCGTGTGCTGGATGCTGATCGGTTATGCATGCGGCTATACCAGTGCCTTCATGGG
CCGTCCCATCCTGTGGAGGGAAACCGAATGCCGGGGGATGGGGCATGTGAAATGCCGCGTGGTAGGCAAGCCGGTGGAGG
AATGGGAAGACGCCCAGGACGACCTGCGCTTCCTGAGGATCGGCGATTTCGTCAAATGGGCACCGGTGGACGAGGCGCCC
CTGCCCGCCACGAGCCGCATCGCGGCGCGGCTGTCCAGCGCCCCGGAGAACAGCTTCGGCGTGGTCGGCATCTCCGCCGG
CTTCAACACCGTCTGCCACATGGTCAACAAGGTGGCGCCCACCGACGCCACCGTGCTGTTCCTGGGGGAAAGCGGTGTTG
GCAAGGAAGTCTTTGCGAACAACCTGCATCGCCTGAGCAAGCGCGCCGACGGCCCTTACGTCGCGGTGAACTGTGCGTCC
ATTCCGGAACACCTGATGGAATCCGAGTTATTCGGCGTCGAGCGCGGCGGCTTTACGGGCGCCACCACATCCCGCGCCGG
CCGCTTCGAGCGGGCCGATGGTGGCACGCTGTTTCTCGACGAGGTCGGCACACTGAGCTTCACGGCACAGGGAAAGCTGC
TGCGCGCGCTACAGCAGGGTGAGATCGAGCGTGTGGGCGATACACGCACCCGGAAAGTCAACGTCAGGGTGGTTGCCGCC
ACGAACGTGAACCTGCGTGAAGCTGTCAAGGCTGGCCACTTCCGCGAGGATCTGTTCTTCCGGCTGAACGTCTTTCCGAT
CCAGGTGCCGCCGCTGCGAGAGCGCCGCGACGACATCCCGCTGATGATGAACTGGTTCCTCCAGCGCATGGCACGCAAGC
ATGACAAGCACATCACCGGCTTCCGCGAACGCGCCGTGGACGCGATGTTCGCCTATGACTGGCCCGGCAACGTCCGAGAG
CTGGAGAACATGATCGAGCGCGCGGTCATTCTGGCCGAGGACGGTGGCGCGCTCGACCTGTGCCACCTGTTCACCAGCGG
CGAGGAAGTTGATACCACCGCTTTCATGCTGAAGCGCAGCGGCAGCATCGGACGCGTCAGCGAAGCCAGCGAAGCGGAAT
CGCCGCCGAGCGCTGCCGAAGGGCGACCTGGTCTGGCCGAAACGGAGGTGGCCATGCTGCGTGCAGCCGTTGCCGAAGCC
AACGGCAATCTGTCGCGCGCAGCCCGGGTGTTGGGAATCAGCCGTCCGACGCTGGCGTACAGGCTGCAGAAATACGGCAT
TACGCCTGAAGCGCAATGA

Upstream 100 bases:

>100_bases
CCTGCGGGGGCCGGTGGATATCGGTCCCCGGACTGGACCGCGCGAGGCGCGACACCGCGCTCGCGCGTCCGCAACCGCGC
CAGTCGCGATTGAGGAAATC

Downstream 100 bases:

>100_bases
CGAAATGCCCCCCGGCGCGGCCGCATAGCGCTGCGCCAGGGGGCTCGCTGCGCTAGAAGCGCTTGCGGTATGCCAGAACC
GCGTTGAGCTGCGAATGCCG

Product: Fis-type helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MAKRHPGKPKSGSPAQGHPGRNQKRESPEAIRVPAIHDLAKRLRFAPQQGRIWLDDQRMMLMHISSLGALRQELIESLGK
ETARGLITRIGYQAGTRDAAMARKVRAGLNTYDDFLAGPQLVSLEGMVHCEPVALDIDVQRGHYFGDFYLVDSSEAEAHI
AGYGIGNESVCWMLIGYACGYTSAFMGRPILWRETECRGMGHVKCRVVGKPVEEWEDAQDDLRFLRIGDFVKWAPVDEAP
LPATSRIAARLSSAPENSFGVVGISAGFNTVCHMVNKVAPTDATVLFLGESGVGKEVFANNLHRLSKRADGPYVAVNCAS
IPEHLMESELFGVERGGFTGATTSRAGRFERADGGTLFLDEVGTLSFTAQGKLLRALQQGEIERVGDTRTRKVNVRVVAA
TNVNLREAVKAGHFREDLFFRLNVFPIQVPPLRERRDDIPLMMNWFLQRMARKHDKHITGFRERAVDAMFAYDWPGNVRE
LENMIERAVILAEDGGALDLCHLFTSGEEVDTTAFMLKRSGSIGRVSEASEAESPPSAAEGRPGLAETEVAMLRAAVAEA
NGNLSRAARVLGISRPTLAYRLQKYGITPEAQ

Sequences:

>Translated_592_residues
MAKRHPGKPKSGSPAQGHPGRNQKRESPEAIRVPAIHDLAKRLRFAPQQGRIWLDDQRMMLMHISSLGALRQELIESLGK
ETARGLITRIGYQAGTRDAAMARKVRAGLNTYDDFLAGPQLVSLEGMVHCEPVALDIDVQRGHYFGDFYLVDSSEAEAHI
AGYGIGNESVCWMLIGYACGYTSAFMGRPILWRETECRGMGHVKCRVVGKPVEEWEDAQDDLRFLRIGDFVKWAPVDEAP
LPATSRIAARLSSAPENSFGVVGISAGFNTVCHMVNKVAPTDATVLFLGESGVGKEVFANNLHRLSKRADGPYVAVNCAS
IPEHLMESELFGVERGGFTGATTSRAGRFERADGGTLFLDEVGTLSFTAQGKLLRALQQGEIERVGDTRTRKVNVRVVAA
TNVNLREAVKAGHFREDLFFRLNVFPIQVPPLRERRDDIPLMMNWFLQRMARKHDKHITGFRERAVDAMFAYDWPGNVRE
LENMIERAVILAEDGGALDLCHLFTSGEEVDTTAFMLKRSGSIGRVSEASEAESPPSAAEGRPGLAETEVAMLRAAVAEA
NGNLSRAARVLGISRPTLAYRLQKYGITPEAQ
>Mature_591_residues
AKRHPGKPKSGSPAQGHPGRNQKRESPEAIRVPAIHDLAKRLRFAPQQGRIWLDDQRMMLMHISSLGALRQELIESLGKE
TARGLITRIGYQAGTRDAAMARKVRAGLNTYDDFLAGPQLVSLEGMVHCEPVALDIDVQRGHYFGDFYLVDSSEAEAHIA
GYGIGNESVCWMLIGYACGYTSAFMGRPILWRETECRGMGHVKCRVVGKPVEEWEDAQDDLRFLRIGDFVKWAPVDEAPL
PATSRIAARLSSAPENSFGVVGISAGFNTVCHMVNKVAPTDATVLFLGESGVGKEVFANNLHRLSKRADGPYVAVNCASI
PEHLMESELFGVERGGFTGATTSRAGRFERADGGTLFLDEVGTLSFTAQGKLLRALQQGEIERVGDTRTRKVNVRVVAAT
NVNLREAVKAGHFREDLFFRLNVFPIQVPPLRERRDDIPLMMNWFLQRMARKHDKHITGFRERAVDAMFAYDWPGNVREL
ENMIERAVILAEDGGALDLCHLFTSGEEVDTTAFMLKRSGSIGRVSEASEAESPPSAAEGRPGLAETEVAMLRAAVAEAN
GNLSRAARVLGISRPTLAYRLQKYGITPEAQ

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=356, Percent_Identity=42.1348314606742, Blast_Score=272, Evalue=5e-74,
Organism=Escherichia coli, GI87082117, Length=331, Percent_Identity=45.9214501510574, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1788550, Length=325, Percent_Identity=43.3846153846154, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI1789087, Length=344, Percent_Identity=41.5697674418605, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1789233, Length=415, Percent_Identity=34.4578313253012, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI87082152, Length=232, Percent_Identity=50.8620689655172, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1790299, Length=344, Percent_Identity=40.9883720930233, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI87081872, Length=329, Percent_Identity=39.8176291793313, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1788905, Length=307, Percent_Identity=39.7394136807818, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1786524, Length=336, Percent_Identity=37.797619047619, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1787583, Length=331, Percent_Identity=35.3474320241692, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI87081858, Length=321, Percent_Identity=31.1526479750779, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1789828, Length=268, Percent_Identity=32.4626865671642, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 65143; Mature: 65012

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRHPGKPKSGSPAQGHPGRNQKRESPEAIRVPAIHDLAKRLRFAPQQGRIWLDDQRMM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCCEEECCCCEE
LMHISSLGALRQELIESLGKETARGLITRIGYQAGTRDAAMARKVRAGLNTYDDFLAGPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHCCCC
LVSLEGMVHCEPVALDIDVQRGHYFGDFYLVDSSEAEAHIAGYGIGNESVCWMLIGYACG
EEEECCEEEECEEEEEEEECCCCEEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHC
YTSAFMGRPILWRETECRGMGHVKCRVVGKPVEEWEDAQDDLRFLRIGDFVKWAPVDEAP
HHHHHHCCCCEEECCCCCCCCCEEEEEECCCHHHHCCHHHHHHHHHHCCCEEECCCCCCC
LPATSRIAARLSSAPENSFGVVGISAGFNTVCHMVNKVAPTDATVLFLGESGVGKEVFAN
CCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
NLHRLSKRADGPYVAVNCASIPEHLMESELFGVERGGFTGATTSRAGRFERADGGTLFLD
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
EVGTLSFTAQGKLLRALQQGEIERVGDTRTRKVNVRVVAATNVNLREAVKAGHFREDLFF
CCCCEEEECCHHHHHHHHHCCHHHCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCCCEEE
RLNVFPIQVPPLRERRDDIPLMMNWFLQRMARKHDKHITGFRERAVDAMFAYDWPGNVRE
EEEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHH
LENMIERAVILAEDGGALDLCHLFTSGEEVDTTAFMLKRSGSIGRVSEASEAESPPSAAE
HHHHHHHEEEEECCCCCEEEEHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GRPGLAETEVAMLRAAVAEANGNLSRAARVLGISRPTLAYRLQKYGITPEAQ
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKRHPGKPKSGSPAQGHPGRNQKRESPEAIRVPAIHDLAKRLRFAPQQGRIWLDDQRMM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCCEEECCCCEE
LMHISSLGALRQELIESLGKETARGLITRIGYQAGTRDAAMARKVRAGLNTYDDFLAGPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHCCCC
LVSLEGMVHCEPVALDIDVQRGHYFGDFYLVDSSEAEAHIAGYGIGNESVCWMLIGYACG
EEEECCEEEECEEEEEEEECCCCEEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHC
YTSAFMGRPILWRETECRGMGHVKCRVVGKPVEEWEDAQDDLRFLRIGDFVKWAPVDEAP
HHHHHHCCCCEEECCCCCCCCCEEEEEECCCHHHHCCHHHHHHHHHHCCCEEECCCCCCC
LPATSRIAARLSSAPENSFGVVGISAGFNTVCHMVNKVAPTDATVLFLGESGVGKEVFAN
CCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
NLHRLSKRADGPYVAVNCASIPEHLMESELFGVERGGFTGATTSRAGRFERADGGTLFLD
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
EVGTLSFTAQGKLLRALQQGEIERVGDTRTRKVNVRVVAATNVNLREAVKAGHFREDLFF
CCCCEEEECCHHHHHHHHHCCHHHCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCCCEEE
RLNVFPIQVPPLRERRDDIPLMMNWFLQRMARKHDKHITGFRERAVDAMFAYDWPGNVRE
EEEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHH
LENMIERAVILAEDGGALDLCHLFTSGEEVDTTAFMLKRSGSIGRVSEASEAESPPSAAE
HHHHHHHEEEEECCCCCEEEEHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GRPGLAETEVAMLRAAVAEANGNLSRAARVLGISRPTLAYRLQKYGITPEAQ
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]