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The map label for this gene is yaaU [H]

Identifier: 73538670

GI number: 73538670

Start: 1553634

End: 1555007

Strand: Direct

Name: yaaU [H]

Synonym: Reut_B4845

Alternate gene names: 73538670

Gene position: 1553634-1555007 (Clockwise)

Preceding gene: 73538663

Following gene: 73538671

Centisome position: 56.99

GC content: 68.2

Gene sequence:

>1374_bases
GTGGTGCTCGCGCTGGGCATCGCCTGGGTGCTCGACGGCCTCGAGGTCACGCTGGTCGGCTCGGTCGGCGCCGTGCTGGA
GCGCCGCGACACGCTGGCGCTTACCGCGACCGAGGTCGGCTGGACGGGTTCGTTTTATGTTGGCGGCGCCGTGCTCGGCG
CGCTGTTGTTCGGCCGCATGGCCGACCGGCTCGGCCGCAAGCGGCTGTTCCTTGTCACGCTGCTGGTCTACATGGCCGCC
ACGCTAGCGACGGCGTTTTCAACAGGCTTCGCCATGTTCGCGGTGTGCCGGTTCTTTACCGGCCTTGGCATTGGCGGCGA
ATATGCCGCCATCAATTCCGCCATCGACGAACTCATTCCCGCGCGTGTGCGCGGCCGCGTGAACCTGGCGATCAACGGCA
GCTTCTGGGTCGGCGCCGCGCTCGGAGCCGGGCTGAGCCTGCTGCTGCTCGACCCGCGCGTGCTGGGTCCCGTGTGGGGC
TGGCGCGCATGTTTCGCACTGGGCGCGGTGCTGGCCGTTGCCATCATGCTGGTGCGCCGGCATGTGCCGGAAAGCCCGCG
CTGGCTGGCCATGCACGGCCGCATCGGCGAAGCGGAACACGTGATTGCGGACATCGAGGCGCAGGTCTTCCCCACAGTGC
GGATGCGCGCGGGCTCGCCGGCCGCAGCATCGCACATTCACGTCCCGACGCCACCGCCGTCCATACGCGATGTGCTGCGC
CTGCTGGTGCTGCGCTATCGGCAGCGCAGCCTGATTACGCTGGCCCTCATGCTGGCGCAGGCCTTCTTCTACAACGCGAT
CTTTTTCTCCTACGCACTCGTGCTGACACGCTTCTACGGCGTGCCGGATGGCCGTGTCGCGCTTTACCTGTTCCCGTTCG
CGCTGGGCAATGCAGTGGGGCCGCTGGTCCTCGGCCCTTTGTTCGACGAGGTCGGCCGGCGCCGCATGATTGCGGCCACT
TACGTGCTGTCTGGCCTCGGCCTGGCCGCCACCGGGTGGGCGTTCACGCAAGGCTGGCTCGACGCTGCCACGCAGGCGCT
GTGCTGGTCCGCCGTGTTCTTCCTGGCTTCGGCCGCCGCCAGCTCGGCGTACCTGACCGCCAGCGAGGTCTTTCCTCTCG
AAATGCGCGCGCTTGCGATCTCGGTCTTCTATGCGGTGGGCACCGGCACCGGCGGCTTCATCGCACCCGTGCTGCTTGGC
ACTTTGATCGAACGCGGCAGCCGTGAAGCGGTCGCGGCCGGCTACGGGCTCGGCGCCGCACTGGTCATTGCGGCCGGCCT
GCTGGCATTGCGCTACGGGATCGATGCCGAGCGGCGCCCGCTCGAGGAGATTGCCCCGCCATTGGCAAGCGGCCGACACG
AAGAAACTGGTTGA

Upstream 100 bases:

>100_bases
CATTTCGACGAGAAGCAGCCTTTCCTCTCCGACCGACGACCGGCAGGCCAGCATCCCCGCGCGGCTTGACCGCCTGCCGT
GGTCGCGTTGGCACTGGCGC

Downstream 100 bases:

>100_bases
CGGAAATCGGCAGATACTCATACCGCGCCTTTAAAAGTAACAACCATGCAGCTTTTGTTTAATTCACGCGGTAATATACA
AAAGGCGTCTATTCATATAG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MVLALGIAWVLDGLEVTLVGSVGAVLERRDTLALTATEVGWTGSFYVGGAVLGALLFGRMADRLGRKRLFLVTLLVYMAA
TLATAFSTGFAMFAVCRFFTGLGIGGEYAAINSAIDELIPARVRGRVNLAINGSFWVGAALGAGLSLLLLDPRVLGPVWG
WRACFALGAVLAVAIMLVRRHVPESPRWLAMHGRIGEAEHVIADIEAQVFPTVRMRAGSPAAASHIHVPTPPPSIRDVLR
LLVLRYRQRSLITLALMLAQAFFYNAIFFSYALVLTRFYGVPDGRVALYLFPFALGNAVGPLVLGPLFDEVGRRRMIAAT
YVLSGLGLAATGWAFTQGWLDAATQALCWSAVFFLASAAASSAYLTASEVFPLEMRALAISVFYAVGTGTGGFIAPVLLG
TLIERGSREAVAAGYGLGAALVIAAGLLALRYGIDAERRPLEEIAPPLASGRHEETG

Sequences:

>Translated_457_residues
MVLALGIAWVLDGLEVTLVGSVGAVLERRDTLALTATEVGWTGSFYVGGAVLGALLFGRMADRLGRKRLFLVTLLVYMAA
TLATAFSTGFAMFAVCRFFTGLGIGGEYAAINSAIDELIPARVRGRVNLAINGSFWVGAALGAGLSLLLLDPRVLGPVWG
WRACFALGAVLAVAIMLVRRHVPESPRWLAMHGRIGEAEHVIADIEAQVFPTVRMRAGSPAAASHIHVPTPPPSIRDVLR
LLVLRYRQRSLITLALMLAQAFFYNAIFFSYALVLTRFYGVPDGRVALYLFPFALGNAVGPLVLGPLFDEVGRRRMIAAT
YVLSGLGLAATGWAFTQGWLDAATQALCWSAVFFLASAAASSAYLTASEVFPLEMRALAISVFYAVGTGTGGFIAPVLLG
TLIERGSREAVAAGYGLGAALVIAAGLLALRYGIDAERRPLEEIAPPLASGRHEETG
>Mature_457_residues
MVLALGIAWVLDGLEVTLVGSVGAVLERRDTLALTATEVGWTGSFYVGGAVLGALLFGRMADRLGRKRLFLVTLLVYMAA
TLATAFSTGFAMFAVCRFFTGLGIGGEYAAINSAIDELIPARVRGRVNLAINGSFWVGAALGAGLSLLLLDPRVLGPVWG
WRACFALGAVLAVAIMLVRRHVPESPRWLAMHGRIGEAEHVIADIEAQVFPTVRMRAGSPAAASHIHVPTPPPSIRDVLR
LLVLRYRQRSLITLALMLAQAFFYNAIFFSYALVLTRFYGVPDGRVALYLFPFALGNAVGPLVLGPLFDEVGRRRMIAAT
YVLSGLGLAATGWAFTQGWLDAATQALCWSAVFFLASAAASSAYLTASEVFPLEMRALAISVFYAVGTGTGGFIAPVLLG
TLIERGSREAVAAGYGLGAALVIAAGLLALRYGIDAERRPLEEIAPPLASGRHEETG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=270, Percent_Identity=25.5555555555556, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI11415038, Length=379, Percent_Identity=23.4828496042216, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI73695465, Length=219, Percent_Identity=25.5707762557078, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI262399383, Length=222, Percent_Identity=25.6756756756757, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI166197673, Length=176, Percent_Identity=29.5454545454545, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI216548223, Length=222, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI166064021, Length=364, Percent_Identity=25.8241758241758, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786229, Length=425, Percent_Identity=24.9411764705882, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788074, Length=184, Percent_Identity=32.0652173913043, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082231, Length=209, Percent_Identity=27.7511961722488, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082404, Length=183, Percent_Identity=26.775956284153, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082159, Length=221, Percent_Identity=28.5067873303167, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788068, Length=424, Percent_Identity=24.0566037735849, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789207, Length=483, Percent_Identity=23.3954451345756, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193202825, Length=394, Percent_Identity=26.6497461928934, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71986689, Length=394, Percent_Identity=26.6497461928934, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17565976, Length=303, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319718, Length=313, Percent_Identity=26.8370607028754, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323512, Length=445, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320766, Length=378, Percent_Identity=24.8677248677249, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324400, Length=382, Percent_Identity=24.6073298429319, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649618, Length=373, Percent_Identity=23.3243967828418, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640198, Length=174, Percent_Identity=28.735632183908, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640196, Length=174, Percent_Identity=28.735632183908, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640200, Length=174, Percent_Identity=28.735632183908, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221330907, Length=321, Percent_Identity=25.5451713395639, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355657, Length=347, Percent_Identity=26.8011527377522, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 48512; Mature: 48512

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00095 C5_MTASE_2 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLALGIAWVLDGLEVTLVGSVGAVLERRDTLALTATEVGWTGSFYVGGAVLGALLFGRM
CEEEEEHHHHHCCCEEEEECHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
ADRLGRKRLFLVTLLVYMAATLATAFSTGFAMFAVCRFFTGLGIGGEYAAINSAIDELIP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
ARVRGRVNLAINGSFWVGAALGAGLSLLLLDPRVLGPVWGWRACFALGAVLAVAIMLVRR
HHHCCEEEEEEECCCHHHHHHHCCCEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
HVPESPRWLAMHGRIGEAEHVIADIEAQVFPTVRMRAGSPAAASHIHVPTPPPSIRDVLR
HCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCCCCHHHHHH
LLVLRYRQRSLITLALMLAQAFFYNAIFFSYALVLTRFYGVPDGRVALYLFPFALGNAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCHH
PLVLGPLFDEVGRRRMIAATYVLSGLGLAATGWAFTQGWLDAATQALCWSAVFFLASAAA
HHHHHHHHHHHCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSAYLTASEVFPLEMRALAISVFYAVGTGTGGFIAPVLLGTLIERGSREAVAAGYGLGAA
CCCEEEHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHH
LVIAAGLLALRYGIDAERRPLEEIAPPLASGRHEETG
HHHHHHHHHHHHCCCCCCCCHHHHCCCHHCCCCCCCC
>Mature Secondary Structure
MVLALGIAWVLDGLEVTLVGSVGAVLERRDTLALTATEVGWTGSFYVGGAVLGALLFGRM
CEEEEEHHHHHCCCEEEEECHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
ADRLGRKRLFLVTLLVYMAATLATAFSTGFAMFAVCRFFTGLGIGGEYAAINSAIDELIP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
ARVRGRVNLAINGSFWVGAALGAGLSLLLLDPRVLGPVWGWRACFALGAVLAVAIMLVRR
HHHCCEEEEEEECCCHHHHHHHCCCEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
HVPESPRWLAMHGRIGEAEHVIADIEAQVFPTVRMRAGSPAAASHIHVPTPPPSIRDVLR
HCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCCCCHHHHHH
LLVLRYRQRSLITLALMLAQAFFYNAIFFSYALVLTRFYGVPDGRVALYLFPFALGNAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCHH
PLVLGPLFDEVGRRRMIAATYVLSGLGLAATGWAFTQGWLDAATQALCWSAVFFLASAAA
HHHHHHHHHHHCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSAYLTASEVFPLEMRALAISVFYAVGTGTGGFIAPVLLGTLIERGSREAVAAGYGLGAA
CCCEEEHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHH
LVIAAGLLALRYGIDAERRPLEEIAPPLASGRHEETG
HHHHHHHHHHHHCCCCCCCCHHHHCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]