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The map label for this gene is fadE [H]

Identifier: 73538615

GI number: 73538615

Start: 1488527

End: 1489714

Strand: Reverse

Name: fadE [H]

Synonym: Reut_B4790

Alternate gene names: 73538615

Gene position: 1489714-1488527 (Counterclockwise)

Preceding gene: 73538616

Following gene: 73538614

Centisome position: 54.65

GC content: 66.08

Gene sequence:

>1188_bases
ATGAAGCTGACTTTTTCCCCCGCCGACGAGGCGTTTCGCCAGGAGGTGCGTGCGTTCGTCAAGGCGAACCTGCCCGCCGA
TATCCGGCGCAAGGTCGAACTGGGCCTGCGCCTGGAGCACGCCGACTACGTGACGTGGTTCCGCATTCTCGAAGCGCGCG
GCTGGCTCACGCCGGGCTGGCCCGTCGAGCACGGCGGACCGGGCTGGAACCACGTGCAGCGCTATATCTTCGACGAAGAA
ACCATGCTCGGCGGCGCGCCGCGCATCATCGCCAGCGGCATCCAGATGCTGGGCCCGGTGCTGATCGCATTCGGCACGCC
CGAGCAGAAGGCGAAGTACCTGCCCGATATCCGCCAGAGCAATACGTGGTGGGCGCAGGGCTTCTCCGAACCCGGTGCGG
GTTCCGATCTGGCGGCGGTGCGGACCACCGCGGTGCTGGAGCCGGACGGCAAGCACTTCGTCGTCAACGGCCACAAGGTG
TGGACTTCGTATGCGCACTGGTGCTCGATGATGTTCGCGCTGGTGCGTACGGACCCGAACGCGGCCAAGCCGCAGGAGGG
CATCTCGTTCCTGCTGATCGACATGAACACGCCGGGCGTGCAGGTGCGGCCCATCCGCATGCTCGAAGGCGGCACCGACC
TGAACGAATGCTATCTCGACAATGTGCGCGTGCCGGTGGAGAACCTCGTCGGCGAACTGCACAAGGGCTGGTCCTATGGC
AAGTACCTGCTTGGCCATGAGCGCACCGGCATCGCGGGTATCGGCTCATGCAAGCAGCAATTGCAGCGGGCCCGCGAACT
GGCCGCCAGCCAGGGGCTGGACGGTGATCCGGTGCTGCAGTCACGGCTTGCGCAATTCGAAATCGAACTGCTGGCGCTCG
AGTTCACCGCACTGCGCCTGCTCAGCGCCAACCAGCAGAGCCGCGCCCCGGCGGTGGAAGCGTCGATGCTGAAGGTGCGC
GGCACCGAACTGCGCCAGGCCATCTATGAGCTGCTGGTGGAAATCGCGGGCCCTCAGGCGGTGCCGTTCGAAGAAGCGGC
GCTGCGCGGCGAACTGGACGAACCTGCCAGCCCGCCCGAACTGTCGGCGCTCGCCGCGAACTACCTCGACGCGCGCAAGC
TGTCGATCTACGGCGGCGTCAATGAAGTGCAGCGCAACCTGATCAGCAAGGCCTTCCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
AATCCGCTCGTGGCCTATCCCGACCGCGTGCTCGCGCTCGACGCGTTGGTCGTCTGCGCCCAGGAAGTCTGAAACCCGGC
CTGAACCCACGGCATATATC

Downstream 100 bases:

>100_bases
CAACGTACCGAGACCATGGACTTTTCCCTTAACGACGAACATATCGCGCTGCGCGACGCGGTGCGCCGCTTCTGCGACGG
CGAATACCCGGCGCATCGGC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKLTFSPADEAFRQEVRAFVKANLPADIRRKVELGLRLEHADYVTWFRILEARGWLTPGWPVEHGGPGWNHVQRYIFDEE
TMLGGAPRIIASGIQMLGPVLIAFGTPEQKAKYLPDIRQSNTWWAQGFSEPGAGSDLAAVRTTAVLEPDGKHFVVNGHKV
WTSYAHWCSMMFALVRTDPNAAKPQEGISFLLIDMNTPGVQVRPIRMLEGGTDLNECYLDNVRVPVENLVGELHKGWSYG
KYLLGHERTGIAGIGSCKQQLQRARELAASQGLDGDPVLQSRLAQFEIELLALEFTALRLLSANQQSRAPAVEASMLKVR
GTELRQAIYELLVEIAGPQAVPFEEAALRGELDEPASPPELSALAANYLDARKLSIYGGVNEVQRNLISKAFLAA

Sequences:

>Translated_395_residues
MKLTFSPADEAFRQEVRAFVKANLPADIRRKVELGLRLEHADYVTWFRILEARGWLTPGWPVEHGGPGWNHVQRYIFDEE
TMLGGAPRIIASGIQMLGPVLIAFGTPEQKAKYLPDIRQSNTWWAQGFSEPGAGSDLAAVRTTAVLEPDGKHFVVNGHKV
WTSYAHWCSMMFALVRTDPNAAKPQEGISFLLIDMNTPGVQVRPIRMLEGGTDLNECYLDNVRVPVENLVGELHKGWSYG
KYLLGHERTGIAGIGSCKQQLQRARELAASQGLDGDPVLQSRLAQFEIELLALEFTALRLLSANQQSRAPAVEASMLKVR
GTELRQAIYELLVEIAGPQAVPFEEAALRGELDEPASPPELSALAANYLDARKLSIYGGVNEVQRNLISKAFLAA
>Mature_395_residues
MKLTFSPADEAFRQEVRAFVKANLPADIRRKVELGLRLEHADYVTWFRILEARGWLTPGWPVEHGGPGWNHVQRYIFDEE
TMLGGAPRIIASGIQMLGPVLIAFGTPEQKAKYLPDIRQSNTWWAQGFSEPGAGSDLAAVRTTAVLEPDGKHFVVNGHKV
WTSYAHWCSMMFALVRTDPNAAKPQEGISFLLIDMNTPGVQVRPIRMLEGGTDLNECYLDNVRVPVENLVGELHKGWSYG
KYLLGHERTGIAGIGSCKQQLQRARELAASQGLDGDPVLQSRLAQFEIELLALEFTALRLLSANQQSRAPAVEASMLKVR
GTELRQAIYELLVEIAGPQAVPFEEAALRGELDEPASPPELSALAANYLDARKLSIYGGVNEVQRNLISKAFLAA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI76496475, Length=303, Percent_Identity=27.0627062706271, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4557235, Length=303, Percent_Identity=27.0627062706271, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4557233, Length=352, Percent_Identity=28.6931818181818, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4501857, Length=414, Percent_Identity=24.6376811594203, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI21361497, Length=358, Percent_Identity=25.4189944134078, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4501859, Length=350, Percent_Identity=28.8571428571429, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI4557231, Length=352, Percent_Identity=23.2954545454545, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI187960098, Length=352, Percent_Identity=23.2954545454545, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI226958412, Length=253, Percent_Identity=24.1106719367589, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI7656849, Length=340, Percent_Identity=25.2941176470588, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=23.6994219653179, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI211971008, Length=309, Percent_Identity=25.5663430420712, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI48976061, Length=309, Percent_Identity=25.5663430420712, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081958, Length=305, Percent_Identity=25.5737704918033, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=352, Percent_Identity=30.1136363636364, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=232, Percent_Identity=30.1724137931034, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=211, Percent_Identity=30.8056872037915, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=361, Percent_Identity=25.4847645429363, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=354, Percent_Identity=25.9887005649718, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71990804, Length=275, Percent_Identity=28.7272727272727, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=407, Percent_Identity=24.8157248157248, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=334, Percent_Identity=28.7425149700599, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=204, Percent_Identity=31.3725490196078, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=212, Percent_Identity=28.3018867924528, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=357, Percent_Identity=24.6498599439776, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=357, Percent_Identity=24.9299719887955, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=256, Percent_Identity=26.171875, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=160, Percent_Identity=31.875, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666513, Length=342, Percent_Identity=29.2397660818713, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281363737, Length=297, Percent_Identity=28.2828282828283, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21356377, Length=352, Percent_Identity=27.5568181818182, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24660351, Length=358, Percent_Identity=26.2569832402235, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24646207, Length=344, Percent_Identity=26.7441860465116, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355753, Length=199, Percent_Identity=26.1306532663317, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43636; Mature: 43636

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTFSPADEAFRQEVRAFVKANLPADIRRKVELGLRLEHADYVTWFRILEARGWLTPGW
CEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCEEEEHHHHHHHHHHHHHCCCCCCCC
PVEHGGPGWNHVQRYIFDEETMLGGAPRIIASGIQMLGPVLIAFGTPEQKAKYLPDIRQS
CCCCCCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHEEEEECCCHHHHHHCCCCCCC
NTWWAQGFSEPGAGSDLAAVRTTAVLEPDGKHFVVNGHKVWTSYAHWCSMMFALVRTDPN
CCHHCCCCCCCCCCCCHHHHHEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCC
AAKPQEGISFLLIDMNTPGVQVRPIRMLEGGTDLNECYLDNVRVPVENLVGELHKGWSYG
CCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCC
KYLLGHERTGIAGIGSCKQQLQRARELAASQGLDGDPVLQSRLAQFEIELLALEFTALRL
CHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSANQQSRAPAVEASMLKVRGTELRQAIYELLVEIAGPQAVPFEEAALRGELDEPASPPE
HHCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCH
LSALAANYLDARKLSIYGGVNEVQRNLISKAFLAA
HHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLTFSPADEAFRQEVRAFVKANLPADIRRKVELGLRLEHADYVTWFRILEARGWLTPGW
CEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCEEEEHHHHHHHHHHHHHCCCCCCCC
PVEHGGPGWNHVQRYIFDEETMLGGAPRIIASGIQMLGPVLIAFGTPEQKAKYLPDIRQS
CCCCCCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHEEEEECCCHHHHHHCCCCCCC
NTWWAQGFSEPGAGSDLAAVRTTAVLEPDGKHFVVNGHKVWTSYAHWCSMMFALVRTDPN
CCHHCCCCCCCCCCCCHHHHHEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCC
AAKPQEGISFLLIDMNTPGVQVRPIRMLEGGTDLNECYLDNVRVPVENLVGELHKGWSYG
CCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCC
KYLLGHERTGIAGIGSCKQQLQRARELAASQGLDGDPVLQSRLAQFEIELLALEFTALRL
CHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSANQQSRAPAVEASMLKVRGTELRQAIYELLVEIAGPQAVPFEEAALRGELDEPASPPE
HHCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCH
LSALAANYLDARKLSIYGGVNEVQRNLISKAFLAA
HHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]