Click here to switch to the map view.

The map label for this gene is yngJ [H]

Identifier: 73538614

GI number: 73538614

Start: 1487384

End: 1488511

Strand: Reverse

Name: yngJ [H]

Synonym: Reut_B4789

Alternate gene names: 73538614

Gene position: 1488511-1487384 (Counterclockwise)

Preceding gene: 73538615

Following gene: 73538613

Centisome position: 54.6

GC content: 69.15

Gene sequence:

>1128_bases
ATGGACTTTTCCCTTAACGACGAACATATCGCGCTGCGCGACGCGGTGCGCCGCTTCTGCGACGGCGAATACCCGGCGCA
TCGGCGCGGCGATGCCGAGACCGAAGGCGAGGCCGCCGCTCGCTGGACCGCAATGGCCGACCTGGGCCTGCTAGGCCTGC
CGCTTTCGGCAGATGTCGGCGGCAGCGAGCAGGGCCCGACAGAAATGATGCTTGTGGCCCAGGAACTGGGCCGGGCGCTC
GGCGGCGGTGCGTGGCTGTCAAGCGTGGTGCTCGCCGGACAACTGCTCGACCAGGCGGGCACGCCCGCGCAACGGCAGCA
ATGGCTGCCGGCACTGGCAGCGGGGCAATCGCGTCTGGCTCTGGCCATCAACGAGGCCGATGCCCGCTATGACCTGTCTC
GCGTCAGCACGCAGGCGCGCCGCGACAGCGAGGGCTGGGTCATCGACGGAACCAAGACGCTGGTGCTCGATGGCGCGCAA
GCCGATGCCTTCCTCGTGGCGGCACGCACCGCCGGCGATGTCGCGGATGAACAGGGCGTGACGCTGTTTCTCGTTCCGGC
CGATGCGCCCGGACTGTCTGTGCGCGAGTTCGGCACGCTCGATGGCCGCAGCGCGGCGCACCTCACGTTGCGCGAAGTCA
GGGCGGACGAAAACGGGGTAGTCGGGCAGCCCGCCGCCGCGCTACCCGCCATCGTCGCCGCCACCGACCGGGCCAACGCC
GCACTGTGCGCGGAAGCCGTCGGCGCGCTGGAGGCACTGCTCGACCTGACCGCCGAGCAACTGAAGACGCGCAAGCAGTT
TGGCACGCCGCTGGCAAAGTTTCAGGTGTTGCAGCACCGCGTGGCGGACATGCTGATCGCGCTCGAACAGTGCAAGTCGA
TGGCCTGCGTGGCCGCCATGGCGGTGACCGACGGCGACCCGGTGCAGCGTCGCCGGCTGGTGTCGGCGGCCAAGGTGATC
GTCGGGCAGGCGGGCCGGCAGGTCGGCCAGTGGGCCATCCAGATGCATGGCGCGATGGGCATGACCGACGAATGCCGCGT
TGGCCATTACGCCAAGCGCCTCATGGTCATCAACCAGCTGTTCGGCGACGCCGGGCATCACCTGGCTTGTTTTGCCCGGC
AGGCCTGA

Upstream 100 bases:

>100_bases
CCTCGACGCGCGCAAGCTGTCGATCTACGGCGGCGTCAATGAAGTGCAGCGCAACCTGATCAGCAAGGCCTTCCTCGCCG
CCTGACAACGTACCGAGACC

Downstream 100 bases:

>100_bases
CCAGCGCCTGACCGGATCACACAAGAAATACACAGGAGACAAAGACATGGCCCTCATCCGTACCTTCAGATCCGCCTGCG
CCGTGCTAGCGCTGGGGCTG

Product: acyl-CoA dehydrogenase

Products: 6-carboxyhex-2-enoyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MDFSLNDEHIALRDAVRRFCDGEYPAHRRGDAETEGEAAARWTAMADLGLLGLPLSADVGGSEQGPTEMMLVAQELGRAL
GGGAWLSSVVLAGQLLDQAGTPAQRQQWLPALAAGQSRLALAINEADARYDLSRVSTQARRDSEGWVIDGTKTLVLDGAQ
ADAFLVAARTAGDVADEQGVTLFLVPADAPGLSVREFGTLDGRSAAHLTLREVRADENGVVGQPAAALPAIVAATDRANA
ALCAEAVGALEALLDLTAEQLKTRKQFGTPLAKFQVLQHRVADMLIALEQCKSMACVAAMAVTDGDPVQRRRLVSAAKVI
VGQAGRQVGQWAIQMHGAMGMTDECRVGHYAKRLMVINQLFGDAGHHLACFARQA

Sequences:

>Translated_375_residues
MDFSLNDEHIALRDAVRRFCDGEYPAHRRGDAETEGEAAARWTAMADLGLLGLPLSADVGGSEQGPTEMMLVAQELGRAL
GGGAWLSSVVLAGQLLDQAGTPAQRQQWLPALAAGQSRLALAINEADARYDLSRVSTQARRDSEGWVIDGTKTLVLDGAQ
ADAFLVAARTAGDVADEQGVTLFLVPADAPGLSVREFGTLDGRSAAHLTLREVRADENGVVGQPAAALPAIVAATDRANA
ALCAEAVGALEALLDLTAEQLKTRKQFGTPLAKFQVLQHRVADMLIALEQCKSMACVAAMAVTDGDPVQRRRLVSAAKVI
VGQAGRQVGQWAIQMHGAMGMTDECRVGHYAKRLMVINQLFGDAGHHLACFARQA
>Mature_375_residues
MDFSLNDEHIALRDAVRRFCDGEYPAHRRGDAETEGEAAARWTAMADLGLLGLPLSADVGGSEQGPTEMMLVAQELGRAL
GGGAWLSSVVLAGQLLDQAGTPAQRQQWLPALAAGQSRLALAINEADARYDLSRVSTQARRDSEGWVIDGTKTLVLDGAQ
ADAFLVAARTAGDVADEQGVTLFLVPADAPGLSVREFGTLDGRSAAHLTLREVRADENGVVGQPAAALPAIVAATDRANA
ALCAEAVGALEALLDLTAEQLKTRKQFGTPLAKFQVLQHRVADMLIALEQCKSMACVAAMAVTDGDPVQRRRLVSAAKVI
VGQAGRQVGQWAIQMHGAMGMTDECRVGHYAKRLMVINQLFGDAGHHLACFARQA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=348, Percent_Identity=27.5862068965517, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI226958412, Length=360, Percent_Identity=26.1111111111111, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI226958414, Length=321, Percent_Identity=26.791277258567, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI4501859, Length=356, Percent_Identity=25.2808988764045, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4501857, Length=356, Percent_Identity=24.7191011235955, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI7656849, Length=319, Percent_Identity=26.3322884012539, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=26.0526315789474, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7669494, Length=365, Percent_Identity=26.3013698630137, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4557231, Length=311, Percent_Identity=24.1157556270096, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI187960098, Length=311, Percent_Identity=24.1157556270096, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI76496475, Length=360, Percent_Identity=24.4444444444444, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4557235, Length=360, Percent_Identity=24.4444444444444, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI21361497, Length=317, Percent_Identity=24.9211356466877, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI38505218, Length=262, Percent_Identity=22.9007633587786, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081958, Length=355, Percent_Identity=24.5070422535211, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786223, Length=365, Percent_Identity=24.3835616438356, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=356, Percent_Identity=29.2134831460674, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17506239, Length=359, Percent_Identity=25.0696378830084, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17508101, Length=354, Percent_Identity=24.2937853107345, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=359, Percent_Identity=25.6267409470752, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=315, Percent_Identity=26.3492063492064, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=306, Percent_Identity=26.797385620915, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17533517, Length=354, Percent_Identity=23.4463276836158, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=23.6220472440945, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=26.4462809917355, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=267, Percent_Identity=24.3445692883895, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=266, Percent_Identity=25.9398496240602, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17505929, Length=331, Percent_Identity=25.3776435045317, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=277, Percent_Identity=26.3537906137184, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=329, Percent_Identity=23.4042553191489, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=377, Percent_Identity=23.342175066313, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355753, Length=358, Percent_Identity=27.9329608938547, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24646207, Length=349, Percent_Identity=26.647564469914, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356377, Length=355, Percent_Identity=23.3802816901408, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24660351, Length=355, Percent_Identity=25.9154929577465, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=23.4666666666667, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920834, Length=389, Percent_Identity=22.6221079691517, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281363737, Length=353, Percent_Identity=24.6458923512748, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.1.62

Molecular weight: Translated: 39666; Mature: 39666

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLNDEHIALRDAVRRFCDGEYPAHRRGDAETEGEAAARWTAMADLGLLGLPLSADVG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GSEQGPTEMMLVAQELGRALGGGAWLSSVVLAGQLLDQAGTPAQRQQWLPALAAGQSRLA
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHCCCCEEE
LAINEADARYDLSRVSTQARRDSEGWVIDGTKTLVLDGAQADAFLVAARTAGDVADEQGV
EEEECCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCC
TLFLVPADAPGLSVREFGTLDGRSAAHLTLREVRADENGVVGQPAAALPAIVAATDRANA
EEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHEECCCCCH
ALCAEAVGALEALLDLTAEQLKTRKQFGTPLAKFQVLQHRVADMLIALEQCKSMACVAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTDGDPVQRRRLVSAAKVIVGQAGRQVGQWAIQMHGAMGMTDECRVGHYAKRLMVINQL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FGDAGHHLACFARQA
HCCCCCCEEEEECCC
>Mature Secondary Structure
MDFSLNDEHIALRDAVRRFCDGEYPAHRRGDAETEGEAAARWTAMADLGLLGLPLSADVG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GSEQGPTEMMLVAQELGRALGGGAWLSSVVLAGQLLDQAGTPAQRQQWLPALAAGQSRLA
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHCCCCEEE
LAINEADARYDLSRVSTQARRDSEGWVIDGTKTLVLDGAQADAFLVAARTAGDVADEQGV
EEEECCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCC
TLFLVPADAPGLSVREFGTLDGRSAAHLTLREVRADENGVVGQPAAALPAIVAATDRANA
EEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHEECCCCCH
ALCAEAVGALEALLDLTAEQLKTRKQFGTPLAKFQVLQHRVADMLIALEQCKSMACVAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTDGDPVQRRRLVSAAKVIVGQAGRQVGQWAIQMHGAMGMTDECRVGHYAKRLMVINQL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FGDAGHHLACFARQA
HCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pimeloyl-CoA; NAD+

Specific reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]