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The map label for this gene is ttuB [H]

Identifier: 73538601

GI number: 73538601

Start: 1475943

End: 1477271

Strand: Direct

Name: ttuB [H]

Synonym: Reut_B4776

Alternate gene names: 73538601

Gene position: 1475943-1477271 (Clockwise)

Preceding gene: 73538600

Following gene: 73538602

Centisome position: 54.14

GC content: 65.16

Gene sequence:

>1329_bases
ATGAAGACCAAGTACGCCACTTCGCCCATCGCGGGCGAAGCGACGCCGCACGTCGATGCGGCCACGTTCGAGTCCAGCAC
CTACGCCAAGGTCGTTCGCCGGCTCATACCGTTCCTGATGCTGTGCTACCTCGGTGCGTATCTGGACCGGGTCAACGTCG
GCTTCGCCAAGCTGCAGATGCTCAACGACCTGCACTTCAGCGAGACCATCTATGGCCTCGGGGCCGGCATCTTCTTCCTC
GGCTACTTCATCTTCGAGGTTCCGAGCAACGTCATCCTGCACAAGGTCGGCGCCAAAAAATGGCTGGCCCGCATCATGCT
GACCTGGGCAGTGATCTCCGCGAGCTTTGCCTTTGTCAGCACGCCCACGCAGTTCTACGTCCTGCGCTTCCTCCTCGGCG
TCGCCGAGGCGGGCTTCGCCCCGGGCGTGATCCTGTACATGACGTACTGGTTCCCGTCCGAGCGGCGCGCCAAGGCACTG
TCGATGTTCTTCATGGCGATTCCGCTCGCCGGCATCGTGGGCGGGCCGCTCTCGGGCTACATCCTGCACGCATTCCAGGG
TACTGCAGGCATGGATGGCTGGAAGTGGCTGTTCCTGATCGAGGCGCTGCCCTCGCTGGTACTCGGCGTCGCCATCCTGC
TCTACCTCGACAACGGCATCCGCAGCGCGAAGTGGCTGACCGACGCCGAGAAGGCGCTGCTGGAGCGCAACATCGAAGGG
GACAACGCACAGAAGCACGTGCATCTGTCGATCCGCGCGTTCCTGGCCGACCGGCGCCTGTGGCTGATGGCTGCTATCTA
CTTCTGCGTCGTACTCGGGCAGTATGGGCTGACCTTCTGGCTGCCGACGATCATCCGCAAGTCCGGCGTGGCTGATCCGC
TGTGGGTTGGCATCTTCACGGCGCTGCCCTATCTCTGCGCCATCGTCGCGCTGCCGCTGATCGGCGCAAGCGCGGACCGT
CGACGCGAGCGTCGCTTGCATCTGGCTGTGCCGATGCTGGTGTCGGCAGCGGGCTTCGCAACGCTGCCGCTGCTGGGCGG
CGTGGAAGCTTCGCTGCTGTGCCTGTGCGTGGCGGCAGCCGGCATCCTGGCCTCGTCCTCGCAGTTCTGGGCGCTGCCGA
CTGCGCTGCTGGGCGGCATGTCGGCGGCGGCAGGCATCGCGGCGGTCAACTGCGTCGCCAACCTGGCGGGATTCTTCTCG
CCCGCCATCGTGGGTTGGCTCAACGACCTGACGGGCAAGTCGACCGCGGGCCTGCTTTTCATCTCGGCCACGGTGGTCGT
GGGTGCACTGCTCGTCTTCCTCGTGCCGGCCAGATCGGTCAACCGCTGA

Upstream 100 bases:

>100_bases
CATGCTGATCCACTAAATTTCCATTGAAGCCGCCCACAGAGGCGGACCATCAGACGCCCGTGCAGCCGGAGACTTCCGGC
GCACATGGCAGGAGACAACA

Downstream 100 bases:

>100_bases
GCCAGCCATGTACACAGGCTTTCCCTTCGCTCCGACTACCCAATCCACAGGAGACAACATGCATTACGCAACCAACGAGG
TGGCCGTGCCCCTCGCCGAA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKTKYATSPIAGEATPHVDAATFESSTYAKVVRRLIPFLMLCYLGAYLDRVNVGFAKLQMLNDLHFSETIYGLGAGIFFL
GYFIFEVPSNVILHKVGAKKWLARIMLTWAVISASFAFVSTPTQFYVLRFLLGVAEAGFAPGVILYMTYWFPSERRAKAL
SMFFMAIPLAGIVGGPLSGYILHAFQGTAGMDGWKWLFLIEALPSLVLGVAILLYLDNGIRSAKWLTDAEKALLERNIEG
DNAQKHVHLSIRAFLADRRLWLMAAIYFCVVLGQYGLTFWLPTIIRKSGVADPLWVGIFTALPYLCAIVALPLIGASADR
RRERRLHLAVPMLVSAAGFATLPLLGGVEASLLCLCVAAAGILASSSQFWALPTALLGGMSAAAGIAAVNCVANLAGFFS
PAIVGWLNDLTGKSTAGLLFISATVVVGALLVFLVPARSVNR

Sequences:

>Translated_442_residues
MKTKYATSPIAGEATPHVDAATFESSTYAKVVRRLIPFLMLCYLGAYLDRVNVGFAKLQMLNDLHFSETIYGLGAGIFFL
GYFIFEVPSNVILHKVGAKKWLARIMLTWAVISASFAFVSTPTQFYVLRFLLGVAEAGFAPGVILYMTYWFPSERRAKAL
SMFFMAIPLAGIVGGPLSGYILHAFQGTAGMDGWKWLFLIEALPSLVLGVAILLYLDNGIRSAKWLTDAEKALLERNIEG
DNAQKHVHLSIRAFLADRRLWLMAAIYFCVVLGQYGLTFWLPTIIRKSGVADPLWVGIFTALPYLCAIVALPLIGASADR
RRERRLHLAVPMLVSAAGFATLPLLGGVEASLLCLCVAAAGILASSSQFWALPTALLGGMSAAAGIAAVNCVANLAGFFS
PAIVGWLNDLTGKSTAGLLFISATVVVGALLVFLVPARSVNR
>Mature_442_residues
MKTKYATSPIAGEATPHVDAATFESSTYAKVVRRLIPFLMLCYLGAYLDRVNVGFAKLQMLNDLHFSETIYGLGAGIFFL
GYFIFEVPSNVILHKVGAKKWLARIMLTWAVISASFAFVSTPTQFYVLRFLLGVAEAGFAPGVILYMTYWFPSERRAKAL
SMFFMAIPLAGIVGGPLSGYILHAFQGTAGMDGWKWLFLIEALPSLVLGVAILLYLDNGIRSAKWLTDAEKALLERNIEG
DNAQKHVHLSIRAFLADRRLWLMAAIYFCVVLGQYGLTFWLPTIIRKSGVADPLWVGIFTALPYLCAIVALPLIGASADR
RRERRLHLAVPMLVSAAGFATLPLLGGVEASLLCLCVAAAGILASSSQFWALPTALLGGMSAAAGIAAVNCVANLAGFFS
PAIVGWLNDLTGKSTAGLLFISATVVVGALLVFLVPARSVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=410, Percent_Identity=38.0487804878049, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI2367379, Length=417, Percent_Identity=23.5011990407674, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1789152, Length=463, Percent_Identity=22.2462203023758, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789515, Length=419, Percent_Identity=21.0023866348449, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32565914, Length=388, Percent_Identity=23.9690721649485, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=238, Percent_Identity=28.1512605042017, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=349, Percent_Identity=23.4957020057307, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324410, Length=170, Percent_Identity=27.6470588235294, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323032, Length=265, Percent_Identity=25.2830188679245, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=262, Percent_Identity=24.0458015267176, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321502, Length=250, Percent_Identity=24, Blast_Score=63, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24654215, Length=376, Percent_Identity=23.936170212766, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19922400, Length=376, Percent_Identity=23.936170212766, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47724; Mature: 47724

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKYATSPIAGEATPHVDAATFESSTYAKVVRRLIPFLMLCYLGAYLDRVNVGFAKLQM
CCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LNDLHFSETIYGLGAGIFFLGYFIFEVPSNVILHKVGAKKWLARIMLTWAVISASFAFVS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPTQFYVLRFLLGVAEAGFAPGVILYMTYWFPSERRAKALSMFFMAIPLAGIVGGPLSGY
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
ILHAFQGTAGMDGWKWLFLIEALPSLVLGVAILLYLDNGIRSAKWLTDAEKALLERNIEG
HHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
DNAQKHVHLSIRAFLADRRLWLMAAIYFCVVLGQYGLTFWLPTIIRKSGVADPLWVGIFT
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALPYLCAIVALPLIGASADRRRERRLHLAVPMLVSAAGFATLPLLGGVEASLLCLCVAAA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHH
GILASSSQFWALPTALLGGMSAAAGIAAVNCVANLAGFFSPAIVGWLNDLTGKSTAGLLF
HHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ISATVVVGALLVFLVPARSVNR
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTKYATSPIAGEATPHVDAATFESSTYAKVVRRLIPFLMLCYLGAYLDRVNVGFAKLQM
CCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LNDLHFSETIYGLGAGIFFLGYFIFEVPSNVILHKVGAKKWLARIMLTWAVISASFAFVS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPTQFYVLRFLLGVAEAGFAPGVILYMTYWFPSERRAKALSMFFMAIPLAGIVGGPLSGY
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
ILHAFQGTAGMDGWKWLFLIEALPSLVLGVAILLYLDNGIRSAKWLTDAEKALLERNIEG
HHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
DNAQKHVHLSIRAFLADRRLWLMAAIYFCVVLGQYGLTFWLPTIIRKSGVADPLWVGIFT
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALPYLCAIVALPLIGASADRRRERRLHLAVPMLVSAAGFATLPLLGGVEASLLCLCVAAA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHH
GILASSSQFWALPTALLGGMSAAAGIAAVNCVANLAGFFSPAIVGWLNDLTGKSTAGLLF
HHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ISATVVVGALLVFLVPARSVNR
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]