BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

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The map label for this gene is fabG1 [H]

Identifier: 73538579

GI number: 73538579

Start: 1454236

End: 1455066

Strand: Reverse

Name: fabG1 [H]

Synonym: Reut_B4754

Alternate gene names: 73538579

Gene position: 1455066-1454236 (Counterclockwise)

Preceding gene: 73538580

Following gene: 73538578

Centisome position: 53.37

GC content: 64.5

Gene sequence:

>831_bases
ATGAGAAAACTCGTCGACAAGGTCGCTATCGTTTCGGGTTCGGGCCGCGGCATCGGCCGTGAAATCGCGCTGAAGCTCGC
CAGCGAAGGCGCAGCCGTCGTGATCAACGACCTCGACGCGGAACCGGCACAGGCCGTGGTGCAGGAGATCGTCGCCGCCG
GCGGCAAGGCCGTCGCGTGCGTGGGCAGCGTGACCGAAGCCGATTTCGGCACCCGCTTCGTCGGTACCGCGCTGCAGACC
TTCGGTCGCCTGGACATCATCGTCAACAACGCCGGCTACACCTGGGACAACGTGATCCAGAAGATGACCGACGAACAGTG
GTCGGCCATCATGGACGTGCACGTGACCGCGCCGTTCCGCATTCTGCGCGCCGCCGCTGACTACTTCCGCGAAGCCGCCA
AGAAGGAAGCCGAGGCCGGCCAGGAAGTGTTCCGCAAGGTGGTCAACATCTCGTCGGTATCGGGCGTGATGGGCAACGCC
GGCCAGGCCAACTACTCGGCCGGCAAAGCCGCCATCAACGGCCTGACCAAGGCGCTCGCCAAGGAGTGGGGCCGTTACAA
GGTCAACGTCAACAGCGTGGCGTTCGGCCTGATCAAGACGCGCCTGACCGAGGCCACGGCCGGCTCGGACAACACCTCGA
CGCTGAACATCGGCGGCAACGAGATCAAGGTTGGCGTGAATCCGCAGCTCATGAAAAATATCGAAGCGATGATCCCGCTG
GGCCGTGGCGGCACGCCGGTCGAAGCTGCGGGTTCTGTGTACCTGCTGTGCATCCCCGAGTCGAACTACATCACCGGCCA
GGTGCTGATCTGCGGCGGCGGCCGTCCCTGA

Upstream 100 bases:

>100_bases
CGGGCGAAATCAAGCTGTCAGGCGATGCACTGATCGCCCTTGCCGCCTGAGGCGGCCGGACAGCCGGGACATTCAACAGA
TCAGCAAAGGAGTACAGGAA

Downstream 100 bases:

>100_bases
TCGAAGCGGAGCAAGAGCATGGCATTCAATCAACGTCCCTGGATTACTGACGACCTGGCGATGTTCCAGGACGGCATCCG
CAAGTTCATCGAACGCGAGC

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase 1 [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRKLVDKVAIVSGSGRGIGREIALKLASEGAAVVINDLDAEPAQAVVQEIVAAGGKAVACVGSVTEADFGTRFVGTALQT
FGRLDIIVNNAGYTWDNVIQKMTDEQWSAIMDVHVTAPFRILRAAADYFREAAKKEAEAGQEVFRKVVNISSVSGVMGNA
GQANYSAGKAAINGLTKALAKEWGRYKVNVNSVAFGLIKTRLTEATAGSDNTSTLNIGGNEIKVGVNPQLMKNIEAMIPL
GRGGTPVEAAGSVYLLCIPESNYITGQVLICGGGRP

Sequences:

>Translated_276_residues
MRKLVDKVAIVSGSGRGIGREIALKLASEGAAVVINDLDAEPAQAVVQEIVAAGGKAVACVGSVTEADFGTRFVGTALQT
FGRLDIIVNNAGYTWDNVIQKMTDEQWSAIMDVHVTAPFRILRAAADYFREAAKKEAEAGQEVFRKVVNISSVSGVMGNA
GQANYSAGKAAINGLTKALAKEWGRYKVNVNSVAFGLIKTRLTEATAGSDNTSTLNIGGNEIKVGVNPQLMKNIEAMIPL
GRGGTPVEAAGSVYLLCIPESNYITGQVLICGGGRP
>Mature_276_residues
MRKLVDKVAIVSGSGRGIGREIALKLASEGAAVVINDLDAEPAQAVVQEIVAAGGKAVACVGSVTEADFGTRFVGTALQT
FGRLDIIVNNAGYTWDNVIQKMTDEQWSAIMDVHVTAPFRILRAAADYFREAAKKEAEAGQEVFRKVVNISSVSGVMGNA
GQANYSAGKAAINGLTKALAKEWGRYKVNVNSVAFGLIKTRLTEATAGSDNTSTLNIGGNEIKVGVNPQLMKNIEAMIPL
GRGGTPVEAAGSVYLLCIPESNYITGQVLICGGGRP

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=39.0862944162437, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI15277342, Length=280, Percent_Identity=31.4285714285714, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI32483357, Length=277, Percent_Identity=30.3249097472924, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI40254992, Length=271, Percent_Identity=31.3653136531365, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI10190704, Length=273, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI59889578, Length=253, Percent_Identity=31.6205533596838, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=265, Percent_Identity=29.0566037735849, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI126723750, Length=283, Percent_Identity=26.8551236749117, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI19923817, Length=277, Percent_Identity=24.9097472924188, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4758504, Length=209, Percent_Identity=30.622009569378, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI33667109, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723191, Length=206, Percent_Identity=29.6116504854369, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI209862901, Length=201, Percent_Identity=30.8457711442786, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI19923983, Length=201, Percent_Identity=30.8457711442786, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI4503301, Length=250, Percent_Identity=25.2, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=268, Percent_Identity=35.0746268656716, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788459, Length=274, Percent_Identity=33.5766423357664, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789208, Length=269, Percent_Identity=27.8810408921933, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790717, Length=271, Percent_Identity=28.4132841328413, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082160, Length=269, Percent_Identity=28.6245353159851, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=27.8985507246377, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787905, Length=276, Percent_Identity=28.6231884057971, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI2367175, Length=271, Percent_Identity=29.520295202952, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789378, Length=275, Percent_Identity=30.1818181818182, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789057, Length=275, Percent_Identity=25.4545454545455, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367365, Length=275, Percent_Identity=25.4545454545455, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786812, Length=266, Percent_Identity=25.5639097744361, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=210, Percent_Identity=41.9047619047619, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25147288, Length=269, Percent_Identity=33.0855018587361, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17555706, Length=276, Percent_Identity=30.7971014492754, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17561402, Length=276, Percent_Identity=29.7101449275362, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17562910, Length=279, Percent_Identity=30.4659498207885, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=281, Percent_Identity=30.9608540925267, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=279, Percent_Identity=28.673835125448, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=282, Percent_Identity=29.4326241134752, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=279, Percent_Identity=28.3154121863799, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=283, Percent_Identity=29.6819787985866, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=281, Percent_Identity=28.8256227758007, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=285, Percent_Identity=31.5789473684211, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=283, Percent_Identity=27.5618374558304, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=281, Percent_Identity=27.4021352313167, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=283, Percent_Identity=28.2685512367491, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=279, Percent_Identity=29.3906810035842, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=272, Percent_Identity=28.6764705882353, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=291, Percent_Identity=27.4914089347079, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=282, Percent_Identity=29.4326241134752, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=272, Percent_Identity=27.5735294117647, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=27.8388278388278, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=282, Percent_Identity=26.5957446808511, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=280, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=287, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=290, Percent_Identity=26.8965517241379, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=272, Percent_Identity=25.7352941176471, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=208, Percent_Identity=32.2115384615385, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=203, Percent_Identity=30.0492610837438, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=268, Percent_Identity=26.1194029850746, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=282, Percent_Identity=23.4042553191489, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=181, Percent_Identity=26.5193370165746, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=208, Percent_Identity=40.8653846153846, Blast_Score=148, Evalue=9e-37,
Organism=Drosophila melanogaster, GI18859837, Length=207, Percent_Identity=37.6811594202899, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24639444, Length=274, Percent_Identity=31.7518248175182, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21355319, Length=276, Percent_Identity=29.7101449275362, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28571526, Length=276, Percent_Identity=28.2608695652174, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357041, Length=276, Percent_Identity=27.8985507246377, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24643142, Length=272, Percent_Identity=28.3088235294118, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24644339, Length=270, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17737361, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=273, Percent_Identity=28.9377289377289, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24640492, Length=176, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364892, Length=177, Percent_Identity=26.5536723163842, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28901; Mature: 28901

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLVDKVAIVSGSGRGIGREIALKLASEGAAVVINDLDAEPAQAVVQEIVAAGGKAVAC
CHHHHHHHEEECCCCCCCCHHHHHEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEE
VGSVTEADFGTRFVGTALQTFGRLDIIVNNAGYTWDNVIQKMTDEQWSAIMDVHVTAPFR
ECCCHHCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCHHH
ILRAAADYFREAAKKEAEAGQEVFRKVVNISSVSGVMGNAGQANYSAGKAAINGLTKALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
KEWGRYKVNVNSVAFGLIKTRLTEATAGSDNTSTLNIGGNEIKVGVNPQLMKNIEAMIPL
HHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHEEC
GRGGTPVEAAGSVYLLCIPESNYITGQVLICGGGRP
CCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MRKLVDKVAIVSGSGRGIGREIALKLASEGAAVVINDLDAEPAQAVVQEIVAAGGKAVAC
CHHHHHHHEEECCCCCCCCHHHHHEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEE
VGSVTEADFGTRFVGTALQTFGRLDIIVNNAGYTWDNVIQKMTDEQWSAIMDVHVTAPFR
ECCCHHCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCHHH
ILRAAADYFREAAKKEAEAGQEVFRKVVNISSVSGVMGNAGQANYSAGKAAINGLTKALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
KEWGRYKVNVNSVAFGLIKTRLTEATAGSDNTSTLNIGGNEIKVGVNPQLMKNIEAMIPL
HHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHEEC
GRGGTPVEAAGSVYLLCIPESNYITGQVLICGGGRP
CCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]