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The map label for this gene is aroG [H]

Identifier: 73538111

GI number: 73538111

Start: 937777

End: 938910

Strand: Direct

Name: aroG [H]

Synonym: Reut_B4281

Alternate gene names: 73538111

Gene position: 937777-938910 (Clockwise)

Preceding gene: 73538110

Following gene: 73538112

Centisome position: 34.4

GC content: 64.99

Gene sequence:

>1134_bases
ATGAATACCCCACAGGCATCCACAAACAGCATCGGCGAGGGCTGGCCACATCCCTCCGACCGCACCAGCGGCACCGACGA
TGCCCGCGTCGACGACATCATTCCGCTGCCCCCGCCCGAGCATCTGATCCGGTTCTTCCCCATTGCCGGGACGCCGATCG
AATCGCTGGTCACGGCAACGCGGCAGAGCATTTCCCGGATCCTGCACGGCCAGGATGACCGCCTGCTCGTGATCATGGGA
CCGTGCTCGATCCACGATCCGCGCGCCGCGCTCGACTACGCGCAGCGCTTGATGGCACAGCGCGTGCGCTACGCGGATAC
GCTCGAAATCGTGATGCGTGTGTACTTCGAGAAGCCCCGCACCACCGTGGGCTGGAAGGGTCTGATCAACGACCCGTATC
TCGACGAAAGCTACCGGATCGACGAGGGGCTTCGGATGGCGCGCCATCTGCTGCTGGACATCAACCGCCTCGGGCTACCG
GCGGCCGGCGAGTTCCTGGATGTCATCTCGCCGCAGTACATCGGCGACCTGATCAGCTGGGGCGCAATCGGCGCCCGCAC
GACGGAAAGCCAGGTGCACCGGGAACTGGCGTCGGGCACCTCGGCACCGATCGGATTCAAGAACGGCACCGACGGCAATA
TCAAGATCGCCATCGATGCAATCCAGGCCGCCTCCCGTCCGCATCACTTCCTGGGCGTCCATAAGAACGGGCAGGTCGCG
ACCGTTCACACCCGGGGCAACCCCGACTGCCACGTCATTCTGCGCGGCGGCAAGGTGCCGAACTATGATGCCGATTCCGT
GGCAGCCGCCTGCAAGGATCTCGACGCGGCCGGACTGGACCGCCGGCTGATGGTCGATTGCAGCCACGCCAACAGCAGCA
AGCAGCACTTGCGGCAGATCGACGTCGCACGCGACGTAGCGCGGCAGGTCAGCGGCGGCAGCCGGTCAGTGTTTGGCGTG
ATGGTCGAAAGCCATCTGATCGGTGGTGCGCAAAAATTCACGCCGGGGCAGCACAACCCGTCGGAACTGACGTACGGGCA
GAGCATTACCGACGCCTGCATCGGCTGGGACGACTCCCTCGCGGTGCTCGACATGCTTGCCGAGGCGGTCGCTGCGCGCA
GGCAGAAAGCCTGA

Upstream 100 bases:

>100_bases
TGCTGCCGCCGGGTTGAAAGTGATCTGACACCCGGAGCGCCTGCGGCCCGGCAGAAAGCGGCTACCATACCGGGGCGTCC
CGGTTCACCAAGAGACATCC

Downstream 100 bases:

>100_bases
GCCAAATGTTCCGGTGCTTCCGGCCACTCGACGGCCCGGACGCCTTCAGACACCAACACCCACCCGTCCACGGCCAGCGA
TCGGACTTCTGCTGCACCGC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MNTPQASTNSIGEGWPHPSDRTSGTDDARVDDIIPLPPPEHLIRFFPIAGTPIESLVTATRQSISRILHGQDDRLLVIMG
PCSIHDPRAALDYAQRLMAQRVRYADTLEIVMRVYFEKPRTTVGWKGLINDPYLDESYRIDEGLRMARHLLLDINRLGLP
AAGEFLDVISPQYIGDLISWGAIGARTTESQVHRELASGTSAPIGFKNGTDGNIKIAIDAIQAASRPHHFLGVHKNGQVA
TVHTRGNPDCHVILRGGKVPNYDADSVAAACKDLDAAGLDRRLMVDCSHANSSKQHLRQIDVARDVARQVSGGSRSVFGV
MVESHLIGGAQKFTPGQHNPSELTYGQSITDACIGWDDSLAVLDMLAEAVAARRQKA

Sequences:

>Translated_377_residues
MNTPQASTNSIGEGWPHPSDRTSGTDDARVDDIIPLPPPEHLIRFFPIAGTPIESLVTATRQSISRILHGQDDRLLVIMG
PCSIHDPRAALDYAQRLMAQRVRYADTLEIVMRVYFEKPRTTVGWKGLINDPYLDESYRIDEGLRMARHLLLDINRLGLP
AAGEFLDVISPQYIGDLISWGAIGARTTESQVHRELASGTSAPIGFKNGTDGNIKIAIDAIQAASRPHHFLGVHKNGQVA
TVHTRGNPDCHVILRGGKVPNYDADSVAAACKDLDAAGLDRRLMVDCSHANSSKQHLRQIDVARDVARQVSGGSRSVFGV
MVESHLIGGAQKFTPGQHNPSELTYGQSITDACIGWDDSLAVLDMLAEAVAARRQKA
>Mature_377_residues
MNTPQASTNSIGEGWPHPSDRTSGTDDARVDDIIPLPPPEHLIRFFPIAGTPIESLVTATRQSISRILHGQDDRLLVIMG
PCSIHDPRAALDYAQRLMAQRVRYADTLEIVMRVYFEKPRTTVGWKGLINDPYLDESYRIDEGLRMARHLLLDINRLGLP
AAGEFLDVISPQYIGDLISWGAIGARTTESQVHRELASGTSAPIGFKNGTDGNIKIAIDAIQAASRPHHFLGVHKNGQVA
TVHTRGNPDCHVILRGGKVPNYDADSVAAACKDLDAAGLDRRLMVDCSHANSSKQHLRQIDVARDVARQVSGGSRSVFGV
MVESHLIGGAQKFTPGQHNPSELTYGQSITDACIGWDDSLAVLDMLAEAVAARRQKA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=350, Percent_Identity=62, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1787996, Length=350, Percent_Identity=54.8571428571429, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1788953, Length=338, Percent_Identity=53.5502958579882, Blast_Score=368, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6320240, Length=364, Percent_Identity=50, Blast_Score=351, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6319726, Length=359, Percent_Identity=49.5821727019499, Blast_Score=330, Evalue=2e-91,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 41038; Mature: 41038

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPQASTNSIGEGWPHPSDRTSGTDDARVDDIIPLPPPEHLIRFFPIAGTPIESLVTAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEEECCCCCCHHHHHHHH
RQSISRILHGQDDRLLVIMGPCSIHDPRAALDYAQRLMAQRVRYADTLEIVMRVYFEKPR
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TTVGWKGLINDPYLDESYRIDEGLRMARHLLLDINRLGLPAAGEFLDVISPQYIGDLISW
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHH
GAIGARTTESQVHRELASGTSAPIGFKNGTDGNIKIAIDAIQAASRPHHFLGVHKNGQVA
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCEEEECCCCCEE
TVHTRGNPDCHVILRGGKVPNYDADSVAAACKDLDAAGLDRRLMVDCSHANSSKQHLRQI
EEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCHHCCCCCEEEEEECCCCCHHHHHHHH
DVARDVARQVSGGSRSVFGVMVESHLIGGAQKFTPGQHNPSELTYGQSITDACIGWDDSL
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCEECCCCHHHHHCCCCCHH
AVLDMLAEAVAARRQKA
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTPQASTNSIGEGWPHPSDRTSGTDDARVDDIIPLPPPEHLIRFFPIAGTPIESLVTAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEEECCCCCCHHHHHHHH
RQSISRILHGQDDRLLVIMGPCSIHDPRAALDYAQRLMAQRVRYADTLEIVMRVYFEKPR
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TTVGWKGLINDPYLDESYRIDEGLRMARHLLLDINRLGLPAAGEFLDVISPQYIGDLISW
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHH
GAIGARTTESQVHRELASGTSAPIGFKNGTDGNIKIAIDAIQAASRPHHFLGVHKNGQVA
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCEEEECCCCCEE
TVHTRGNPDCHVILRGGKVPNYDADSVAAACKDLDAAGLDRRLMVDCSHANSSKQHLRQI
EEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCHHCCCCCEEEEEECCCCCHHHHHHHH
DVARDVARQVSGGSRSVFGVMVESHLIGGAQKFTPGQHNPSELTYGQSITDACIGWDDSL
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCEECCCCHHHHHCCCCCHH
AVLDMLAEAVAARRQKA
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]