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The map label for this gene is gbpR [H]

Identifier: 73538110

GI number: 73538110

Start: 936763

End: 937704

Strand: Direct

Name: gbpR [H]

Synonym: Reut_B4280

Alternate gene names: 73538110

Gene position: 936763-937704 (Clockwise)

Preceding gene: 73538097

Following gene: 73538111

Centisome position: 34.36

GC content: 66.77

Gene sequence:

>942_bases
ATGGCCACGATCGACCGCGCGCTGCGCTCCAATATCAAGCTGCGCCACCTGCAACTGCTGGTGGCGCTCGACGAATTCCG
ACACCTGGGCCGCACGGCCGAGTTCCTCGCCGTGAGCCAGCCCGCCGTTTCGCGCGTGCTCACCGAAGTCGAAAAGATGC
TGGGCCTGACGCTGTTCACGCGTTCCACGCGCGGCACCGAACCCACCGCGGCCGGCGAATCACTGGTGCGCTTTGCGCGC
TCGGTGCTCGCGCAGTACGAGCAGACGCGCGACGAGATCGCAGCCGTCGAAAGCGGCGCGTCGGGCCGTATCCGCATCGG
CTCGATGGGCGCGGCGCTGCCGGCATTGCTGGCGCACGCGGTCGGCATGCTCAAGGACCGTTCGCCGCGCGCTACCGTGC
TGATCGAGGAAGGCGATCTCACGCACCTGCTGCCCAAGCTCCGTCTGAGCGAACTGGACCTGATCGTGGGCCGCCTGGAA
CCTGGCTACGCAGCGCCGGACCTGGTTGCCGAGGCCTTGTACGATGATCCCATGGTGGTCGTGGTCAGGCGCGGCCACCG
CATCACGCGCAAGGCCAATCCCGGCTGGCACGACCTCGCCAACCTGCCATGCGTATTCCCGCCGCCGTGGGCCTCGCTGC
GCGTGAAGATCGAACAGGCCTTCTACCAGCACGGACTGCATCCGCCGCAGGACGTCATCGAATCGTCGTCCTACCTTGCA
CTGGCCACGTTTGCCACCAGGCGCGATGCGGCAGGCTTCATGGCACAGTCCGCCGCACGGGCTCTGGAAGCCGAAGGCCG
CCTGCGGATCGTTGCGATGGACGTGCCCGTCGAATTGCCTCCGGTTGGCGTCATGACGTTGCGCGAACGGCCGCTGACGA
GCAGTGCCTTGCAGATGCTGGATTACCTCCGACGTGCTGCCGCCGGGTTGAAAGTGATCTGA

Upstream 100 bases:

>100_bases
AGGCCGTCGTGCTATATCGATATTGTGTGTCCGCCGAACATAACAATCCAATCAGAACTTGGCATTGCTTCATGCCGTTT
TCGTTATGTAGACTCCGGGC

Downstream 100 bases:

>100_bases
CACCCGGAGCGCCTGCGGCCCGGCAGAAAGCGGCTACCATACCGGGGCGTCCCGGTTCACCAAGAGACATCCATGAATAC
CCCACAGGCATCCACAAACA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MATIDRALRSNIKLRHLQLLVALDEFRHLGRTAEFLAVSQPAVSRVLTEVEKMLGLTLFTRSTRGTEPTAAGESLVRFAR
SVLAQYEQTRDEIAAVESGASGRIRIGSMGAALPALLAHAVGMLKDRSPRATVLIEEGDLTHLLPKLRLSELDLIVGRLE
PGYAAPDLVAEALYDDPMVVVVRRGHRITRKANPGWHDLANLPCVFPPPWASLRVKIEQAFYQHGLHPPQDVIESSSYLA
LATFATRRDAAGFMAQSAARALEAEGRLRIVAMDVPVELPPVGVMTLRERPLTSSALQMLDYLRRAAAGLKVI

Sequences:

>Translated_313_residues
MATIDRALRSNIKLRHLQLLVALDEFRHLGRTAEFLAVSQPAVSRVLTEVEKMLGLTLFTRSTRGTEPTAAGESLVRFAR
SVLAQYEQTRDEIAAVESGASGRIRIGSMGAALPALLAHAVGMLKDRSPRATVLIEEGDLTHLLPKLRLSELDLIVGRLE
PGYAAPDLVAEALYDDPMVVVVRRGHRITRKANPGWHDLANLPCVFPPPWASLRVKIEQAFYQHGLHPPQDVIESSSYLA
LATFATRRDAAGFMAQSAARALEAEGRLRIVAMDVPVELPPVGVMTLRERPLTSSALQMLDYLRRAAAGLKVI
>Mature_312_residues
ATIDRALRSNIKLRHLQLLVALDEFRHLGRTAEFLAVSQPAVSRVLTEVEKMLGLTLFTRSTRGTEPTAAGESLVRFARS
VLAQYEQTRDEIAAVESGASGRIRIGSMGAALPALLAHAVGMLKDRSPRATVLIEEGDLTHLLPKLRLSELDLIVGRLEP
GYAAPDLVAEALYDDPMVVVVRRGHRITRKANPGWHDLANLPCVFPPPWASLRVKIEQAFYQHGLHPPQDVIESSSYLAL
ATFATRRDAAGFMAQSAARALEAEGRLRIVAMDVPVELPPVGVMTLRERPLTSSALQMLDYLRRAAAGLKVI

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=297, Percent_Identity=25.2525252525253, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790399, Length=190, Percent_Identity=30.5263157894737, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=27.1186440677966, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789506, Length=177, Percent_Identity=25.9887005649718, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI145693105, Length=207, Percent_Identity=24.1545893719807, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787879, Length=202, Percent_Identity=26.7326732673267, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788887, Length=175, Percent_Identity=29.7142857142857, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788297, Length=219, Percent_Identity=25.5707762557078, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI157672245, Length=231, Percent_Identity=29.004329004329, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI2367136, Length=156, Percent_Identity=30.1282051282051, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI48994962, Length=143, Percent_Identity=29.3706293706294, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787530, Length=266, Percent_Identity=23.6842105263158, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34271; Mature: 34140

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIDRALRSNIKLRHLQLLVALDEFRHLGRTAEFLAVSQPAVSRVLTEVEKMLGLTLFT
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHEE
RSTRGTEPTAAGESLVRFARSVLAQYEQTRDEIAAVESGASGRIRIGSMGAALPALLAHA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHH
VGMLKDRSPRATVLIEEGDLTHLLPKLRLSELDLIVGRLEPGYAAPDLVAEALYDDPMVV
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEE
VVRRGHRITRKANPGWHDLANLPCVFPPPWASLRVKIEQAFYQHGLHPPQDVIESSSYLA
EEECCCEEEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCEE
LATFATRRDAAGFMAQSAARALEAEGRLRIVAMDVPVELPPVGVMTLRERPLTSSALQML
EEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHH
DYLRRAAAGLKVI
HHHHHHHCCCCCC
>Mature Secondary Structure 
ATIDRALRSNIKLRHLQLLVALDEFRHLGRTAEFLAVSQPAVSRVLTEVEKMLGLTLFT
CCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHEE
RSTRGTEPTAAGESLVRFARSVLAQYEQTRDEIAAVESGASGRIRIGSMGAALPALLAHA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHH
VGMLKDRSPRATVLIEEGDLTHLLPKLRLSELDLIVGRLEPGYAAPDLVAEALYDDPMVV
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEE
VVRRGHRITRKANPGWHDLANLPCVFPPPWASLRVKIEQAFYQHGLHPPQDVIESSSYLA
EEECCCEEEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCEE
LATFATRRDAAGFMAQSAARALEAEGRLRIVAMDVPVELPPVGVMTLRERPLTSSALQML
EEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHH
DYLRRAAAGLKVI
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]