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The map label for this gene is luxQ [H]

Identifier: 73537945

GI number: 73537945

Start: 752692

End: 754611

Strand: Reverse

Name: luxQ [H]

Synonym: Reut_B4112

Alternate gene names: 73537945

Gene position: 754611-752692 (Counterclockwise)

Preceding gene: 73537946

Following gene: 73537943

Centisome position: 27.68

GC content: 62.86

Gene sequence:

>1920_bases
ATGTCTGACTCCGGACGCCCTTCCAGCCCCCGCCCCGCGACCGAGCGGCACGATATCTTTCGCACGCTCGTCGAAACAAT
TTCGGACTACGCGATCTTCCTGCTCGATACCGACGGCACGATCACGAGCTGGAACCGCGGCGCGCAGCGGATCAAGGGTT
ACGAAGCGTCAGAGATCATTGGCTCACATTTCTCGCGCTTTTACCCCGAGGATTCGATCGCACGCGGCTGGCCCCAGAAG
GAGCTGGAGCTGGCCAGGCGCCACGGCCGCGTCGAAGACAAAGGCTGGCGCGTGCGCAAGGACGGGACGCGATTCTGGGC
CAATGTCGTGATCACCGCACTGCACAATGAAGCGGGTGAAATCATAGGTTTTGCCAAGATCACGCGGGACATGACGGACC
AGATGCAGGATGCGGCCAAGCTAATGGAGAGCGAAGAGACTTTCCGGCTGCTGGTCCTGAACGTCAAGGACTACGCGATA
TTCATGCTCGATCCGCACGGCAACGTCGTGAGCTGGAACGCGGGTGCTGCGCAGATCAAGGGCTATCGAAGCAGCGAAAT
CGTCGGCCGGCATTTCTCCACGTTCTATCTGCCCGAGGATGTCGCAGCGGGCAAGCCAGAGCGGCTGATCCAGCGGGCCC
GCGAGCATGGCAGCGTGCAAGACGAGGGCTGGCGGATGCGCAAGGACGGCTCGCTGTTCTGGGCCAGTGTCACGCTTACC
GCGATCTATGACGAACATCGCCAGTTGCGCGGCTTCGCCAAGGTGACGCGGGACATGAGCGAACGCAAGCGGCTTGAGGA
GGTCGAGGCTTCGGCGCGCCGGATGAAGGAGTTCCTGGCGATGCTGGCCCACGAACTGAGAAACCCGCTCGCACCGATGT
ACAGCGCCACGTCGATCATGGAGCGCGCGCCGGACGATTTATCGCTGGTCAAGGCGAATCTGGGCATCGTCGGCCGTCAG
TTGCGGCATCTGACCCGGCTGGTCGACGACTTGCTCGATGTCGGCCGCATTGCCGCGGGCAAGCTCGAACTGCGCCGCTC
GGTCATCCCGATCCGCGAGGTGATCGCGGCGGCCATCGAAGGGAGCATGCCCGCGATCGAGGCCAGGTCACAACGCATCG
AAGCGGAACTCGACGATGCGGATTTCCAGGTCTTCGGCGATCTCACGCGCCTGGCGCAGGTGCTGCAGAACCTGTTGATC
AACGCGTCCAAGTTCTCGCCCGAAAGCACGACGATCACCTTGCGCTGCGGCCTGAACGGCCGCATCGGGCAACTGACGAT
TACCGACCAGGGCTGCGGCATCGCCCCGGAAAACCTGTCCGAGGTATTCAACCTCTTCGTGCAAGGCGGACCACCGGGCC
AGACCAGTTCCAACGGGCTAGGCATCGGGCTGTCGCTGTGCCGGTCGATCATTGAACTGCATGAGGGATCGATCAGCGCC
GCCAGCCAGGGGCTTGGCTTGGGCTGCACATTCTCGATCCGGCTTCCGATCATTACCGAACCGCGCACGTCGATGGCTCC
CTTGCTGCGCCGTCCGCAGGAAGGCCTCAACATCTTGCTGGTCGATGACAACCGCGATGCCGCCGACAGCATGGGCCTGC
TGCTGCAGATGACCGGCCACTCGGTCAAGGTTGCCTACGACGGCGTGACGGCACTGCGCAGCGTCGAGGATTTCACGCCC
GACGTCGCGCTCATCGACCTGGCCATGCCGGATATGGACGGCTTCGAGCTGGTGCGCGAACTGCGCGACTACGCCCACCT
GCATCACACCCGCTATTTCGCGCTCACCGGCTTTGGCGATCCCGGCATCAAGGAAGATACGGCTCGCGCTGGTTTTGACG
GGCATCTGGTCAAGCCAGTGGATATCGACGCCATGACTGAAATCCTTCAGCAGACCCAGCACCGGCCCGCCGCCAGGTAG

Upstream 100 bases:

>100_bases
ATCTCGCCCGCATAAGCCTTGTAATTTGTAGGATTCTGTCCGACAGTAACCGAGGCCGCTTTGGGCGACTATTACGGCAG
CCCCTGCCCCCTCCCTGTTC

Downstream 100 bases:

>100_bases
CAGTGGGTCGGGTCACGGCGAATCCTCTCAGCGCTTCTTCTTTGATTGGTTGAGCGCCACGGCCGCCTGGATGAGGGCCT
TCAGCGCCGTCTCGTCGAAC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MSDSGRPSSPRPATERHDIFRTLVETISDYAIFLLDTDGTITSWNRGAQRIKGYEASEIIGSHFSRFYPEDSIARGWPQK
ELELARRHGRVEDKGWRVRKDGTRFWANVVITALHNEAGEIIGFAKITRDMTDQMQDAAKLMESEETFRLLVLNVKDYAI
FMLDPHGNVVSWNAGAAQIKGYRSSEIVGRHFSTFYLPEDVAAGKPERLIQRAREHGSVQDEGWRMRKDGSLFWASVTLT
AIYDEHRQLRGFAKVTRDMSERKRLEEVEASARRMKEFLAMLAHELRNPLAPMYSATSIMERAPDDLSLVKANLGIVGRQ
LRHLTRLVDDLLDVGRIAAGKLELRRSVIPIREVIAAAIEGSMPAIEARSQRIEAELDDADFQVFGDLTRLAQVLQNLLI
NASKFSPESTTITLRCGLNGRIGQLTITDQGCGIAPENLSEVFNLFVQGGPPGQTSSNGLGIGLSLCRSIIELHEGSISA
ASQGLGLGCTFSIRLPIITEPRTSMAPLLRRPQEGLNILLVDDNRDAADSMGLLLQMTGHSVKVAYDGVTALRSVEDFTP
DVALIDLAMPDMDGFELVRELRDYAHLHHTRYFALTGFGDPGIKEDTARAGFDGHLVKPVDIDAMTEILQQTQHRPAAR

Sequences:

>Translated_639_residues
MSDSGRPSSPRPATERHDIFRTLVETISDYAIFLLDTDGTITSWNRGAQRIKGYEASEIIGSHFSRFYPEDSIARGWPQK
ELELARRHGRVEDKGWRVRKDGTRFWANVVITALHNEAGEIIGFAKITRDMTDQMQDAAKLMESEETFRLLVLNVKDYAI
FMLDPHGNVVSWNAGAAQIKGYRSSEIVGRHFSTFYLPEDVAAGKPERLIQRAREHGSVQDEGWRMRKDGSLFWASVTLT
AIYDEHRQLRGFAKVTRDMSERKRLEEVEASARRMKEFLAMLAHELRNPLAPMYSATSIMERAPDDLSLVKANLGIVGRQ
LRHLTRLVDDLLDVGRIAAGKLELRRSVIPIREVIAAAIEGSMPAIEARSQRIEAELDDADFQVFGDLTRLAQVLQNLLI
NASKFSPESTTITLRCGLNGRIGQLTITDQGCGIAPENLSEVFNLFVQGGPPGQTSSNGLGIGLSLCRSIIELHEGSISA
ASQGLGLGCTFSIRLPIITEPRTSMAPLLRRPQEGLNILLVDDNRDAADSMGLLLQMTGHSVKVAYDGVTALRSVEDFTP
DVALIDLAMPDMDGFELVRELRDYAHLHHTRYFALTGFGDPGIKEDTARAGFDGHLVKPVDIDAMTEILQQTQHRPAAR
>Mature_638_residues
SDSGRPSSPRPATERHDIFRTLVETISDYAIFLLDTDGTITSWNRGAQRIKGYEASEIIGSHFSRFYPEDSIARGWPQKE
LELARRHGRVEDKGWRVRKDGTRFWANVVITALHNEAGEIIGFAKITRDMTDQMQDAAKLMESEETFRLLVLNVKDYAIF
MLDPHGNVVSWNAGAAQIKGYRSSEIVGRHFSTFYLPEDVAAGKPERLIQRAREHGSVQDEGWRMRKDGSLFWASVTLTA
IYDEHRQLRGFAKVTRDMSERKRLEEVEASARRMKEFLAMLAHELRNPLAPMYSATSIMERAPDDLSLVKANLGIVGRQL
RHLTRLVDDLLDVGRIAAGKLELRRSVIPIREVIAAAIEGSMPAIEARSQRIEAELDDADFQVFGDLTRLAQVLQNLLIN
ASKFSPESTTITLRCGLNGRIGQLTITDQGCGIAPENLSEVFNLFVQGGPPGQTSSNGLGIGLSLCRSIIELHEGSISAA
SQGLGLGCTFSIRLPIITEPRTSMAPLLRRPQEGLNILLVDDNRDAADSMGLLLQMTGHSVKVAYDGVTALRSVEDFTPD
VALIDLAMPDMDGFELVRELRDYAHLHHTRYFALTGFGDPGIKEDTARAGFDGHLVKPVDIDAMTEILQQTQHRPAAR

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=508, Percent_Identity=26.1811023622047, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788713, Length=404, Percent_Identity=28.7128712871287, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI87081816, Length=400, Percent_Identity=28, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1786912, Length=271, Percent_Identity=29.1512915129151, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788549, Length=403, Percent_Identity=26.7990074441687, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=27.5590551181102, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=25.7246376811594, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1786783, Length=242, Percent_Identity=27.6859504132231, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1786600, Length=251, Percent_Identity=26.6932270916335, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=28.2157676348548, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=29.5833333333333, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=26.7241379310345, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081921, Length=245, Percent_Identity=22.4489795918367, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=23.6051502145923, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=251, Percent_Identity=28.2868525896414, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=30.7017543859649, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789403, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=224, Percent_Identity=25.4464285714286, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71069; Mature: 70938

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSGRPSSPRPATERHDIFRTLVETISDYAIFLLDTDGTITSWNRGAQRIKGYEASEII
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCEECCHHHHHHHCCCCHHHHH
GSHFSRFYPEDSIARGWPQKELELARRHGRVEDKGWRVRKDGTRFWANVVITALHNEAGE
HHHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCHH
IIGFAKITRDMTDQMQDAAKLMESEETFRLLVLNVKDYAIFMLDPHGNVVSWNAGAAQIK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEECCCCCEEEECCCHHHHC
GYRSSEIVGRHFSTFYLPEDVAAGKPERLIQRAREHGSVQDEGWRMRKDGSLFWASVTLT
CCCCHHHHHCCCCEEECCCHHCCCCHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEEEHH
AIYDEHRQLRGFAKVTRDMSERKRLEEVEASARRMKEFLAMLAHELRNPLAPMYSATSIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ERAPDDLSLVKANLGIVGRQLRHLTRLVDDLLDVGRIAAGKLELRRSVIPIREVIAAAIE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GSMPAIEARSQRIEAELDDADFQVFGDLTRLAQVLQNLLINASKFSPESTTITLRCGLNG
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
RIGQLTITDQGCGIAPENLSEVFNLFVQGGPPGQTSSNGLGIGLSLCRSIIELHEGSISA
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH
ASQGLGLGCTFSIRLPIITEPRTSMAPLLRRPQEGLNILLVDDNRDAADSMGLLLQMTGH
HHCCCCCEEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCHHHCCEEEEECCC
SVKVAYDGVTALRSVEDFTPDVALIDLAMPDMDGFELVRELRDYAHLHHTRYFALTGFGD
EEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEEECCC
PGIKEDTARAGFDGHLVKPVDIDAMTEILQQTQHRPAAR
CCCCCCHHCCCCCCCEECCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDSGRPSSPRPATERHDIFRTLVETISDYAIFLLDTDGTITSWNRGAQRIKGYEASEII
CCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCEECCHHHHHHHCCCCHHHHH
GSHFSRFYPEDSIARGWPQKELELARRHGRVEDKGWRVRKDGTRFWANVVITALHNEAGE
HHHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCHH
IIGFAKITRDMTDQMQDAAKLMESEETFRLLVLNVKDYAIFMLDPHGNVVSWNAGAAQIK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEECCCCCEEEECCCHHHHC
GYRSSEIVGRHFSTFYLPEDVAAGKPERLIQRAREHGSVQDEGWRMRKDGSLFWASVTLT
CCCCHHHHHCCCCEEECCCHHCCCCHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEEEHH
AIYDEHRQLRGFAKVTRDMSERKRLEEVEASARRMKEFLAMLAHELRNPLAPMYSATSIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ERAPDDLSLVKANLGIVGRQLRHLTRLVDDLLDVGRIAAGKLELRRSVIPIREVIAAAIE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GSMPAIEARSQRIEAELDDADFQVFGDLTRLAQVLQNLLINASKFSPESTTITLRCGLNG
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
RIGQLTITDQGCGIAPENLSEVFNLFVQGGPPGQTSSNGLGIGLSLCRSIIELHEGSISA
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH
ASQGLGLGCTFSIRLPIITEPRTSMAPLLRRPQEGLNILLVDDNRDAADSMGLLLQMTGH
HHCCCCCEEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCHHHCCEEEEECCC
SVKVAYDGVTALRSVEDFTPDVALIDLAMPDMDGFELVRELRDYAHLHHTRYFALTGFGD
EEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEEECCC
PGIKEDTARAGFDGHLVKPVDIDAMTEILQQTQHRPAAR
CCCCCCHHCCCCCCCEECCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA