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The map label for this gene is cph2 [H]

Identifier: 73537482

GI number: 73537482

Start: 222795

End: 223874

Strand: Reverse

Name: cph2 [H]

Synonym: Reut_B3647

Alternate gene names: 73537482

Gene position: 223874-222795 (Counterclockwise)

Preceding gene: 73537483

Following gene: 73537481

Centisome position: 8.21

GC content: 64.35

Gene sequence:

>1080_bases
ATGCTCAACCAGGACGTTTGGGGCCGAGCCATCAAGGAAGCCAGCATGCAACAACCCGATAACACTGCCATCACCGCTAT
CACCGACACCCCCGCAGCCAACAGCTATCCCGTCATGGTGCTGCTGGTGGACGACCAGGCGATGATTGGCGAGGCCGTAC
GCCGCGCACTGGCCTCAGAGCCGGACATCGATTTCCACTACTGTGCGACGCCGGACGATGCTGTCGCCGTCGCCGAGCGC
ACCCGCCCGACCGTGATCCTGCAGGATCTGGTCATGCCAGGCGTGGACGGCCTGACACTGGTGCGCCGCTACCGCGACAA
CGCGGCCACGCGCGACATCCCGATCATCGTGCTATCCACCAAGGAAGAAGCGGCGATGAAAAGCGCGGCGTTTTCCGCTG
GCGCCAACGACTATCTGGTGAAACTGCCGGACAGCATCGAACTGGTTGCGCGCATCCGCTATCACTCGCGCTCGTACCTG
AACCTGCTGCAGCGTGACGAGGCCTATCGCGCGTTGCGGCAAAGCCAGCAGCAACTGCTCGAAACCAATCTCGAACTGCA
GCGGCTCACCAACTCGGACGGGCTCACGGGGCTGTCCAACCGGCGCTATTTCGACGAGTACCTGAACGCGGAATGGAAGC
GAGCCCAGCGCGAGCAGAGCCAGCTCGCGCTGCTGATGATCGACGTGGACGCGTTCAAAGCCTACAACGATACGTACGGG
CATGTAGCCGGCGACGAAGTCCTGCGGCGCGTGGCCGCTGTGCTGCGCGACAATTGTTCGCGCCCGGCCGACCTGCCTGC
GCGCTTTGGTGGCGAGGAATTTTCGATGGTCCTTCCGTCCACGTCGCCAGGCGGTGCGCGACTGTTTGCGGAGAAAGTCA
GGCGCGCGATTGAATCGCTCGGCATCGCGCACAGCGGCGCGGACACCGGCGGCTTCCTGACCGTCAGCATCGGCGCCGCG
GTGCTCGTGCCGGAAGACGGCCAACCGAGCAGCCGGCTGGTGGAAGTTGCGGATGCGGGGCTGTACGAAGCCAAGCGGAA
CGGGCGCAACCAGGTGGTCATGGCGTGGCCCAGAGCATAG

Upstream 100 bases:

>100_bases
TTGCGCCGCGCCTGGTGCAGGCCTGCTGCAGCGTGCGCCCGCCGCCGGGCTGACAGGCGCAGCAAGAAAACCGATATCAA
CGAGACGACACAGATCGCCG

Downstream 100 bases:

>100_bases
CGGGACGCTGAGCCGTTTATTGATTCGCTGTTCCTGTCGCCCGGCAGGAACACCGCTAGCCGATCCTCCTGTCGGAATCC
TCCGACACCGATTTCGGAGG

Product: response regulator receiver modulated diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MLNQDVWGRAIKEASMQQPDNTAITAITDTPAANSYPVMVLLVDDQAMIGEAVRRALASEPDIDFHYCATPDDAVAVAER
TRPTVILQDLVMPGVDGLTLVRRYRDNAATRDIPIIVLSTKEEAAMKSAAFSAGANDYLVKLPDSIELVARIRYHSRSYL
NLLQRDEAYRALRQSQQQLLETNLELQRLTNSDGLTGLSNRRYFDEYLNAEWKRAQREQSQLALLMIDVDAFKAYNDTYG
HVAGDEVLRRVAAVLRDNCSRPADLPARFGGEEFSMVLPSTSPGGARLFAEKVRRAIESLGIAHSGADTGGFLTVSIGAA
VLVPEDGQPSSRLVEVADAGLYEAKRNGRNQVVMAWPRA

Sequences:

>Translated_359_residues
MLNQDVWGRAIKEASMQQPDNTAITAITDTPAANSYPVMVLLVDDQAMIGEAVRRALASEPDIDFHYCATPDDAVAVAER
TRPTVILQDLVMPGVDGLTLVRRYRDNAATRDIPIIVLSTKEEAAMKSAAFSAGANDYLVKLPDSIELVARIRYHSRSYL
NLLQRDEAYRALRQSQQQLLETNLELQRLTNSDGLTGLSNRRYFDEYLNAEWKRAQREQSQLALLMIDVDAFKAYNDTYG
HVAGDEVLRRVAAVLRDNCSRPADLPARFGGEEFSMVLPSTSPGGARLFAEKVRRAIESLGIAHSGADTGGFLTVSIGAA
VLVPEDGQPSSRLVEVADAGLYEAKRNGRNQVVMAWPRA
>Mature_359_residues
MLNQDVWGRAIKEASMQQPDNTAITAITDTPAANSYPVMVLLVDDQAMIGEAVRRALASEPDIDFHYCATPDDAVAVAER
TRPTVILQDLVMPGVDGLTLVRRYRDNAATRDIPIIVLSTKEEAAMKSAAFSAGANDYLVKLPDSIELVARIRYHSRSYL
NLLQRDEAYRALRQSQQQLLETNLELQRLTNSDGLTGLSNRRYFDEYLNAEWKRAQREQSQLALLMIDVDAFKAYNDTYG
HVAGDEVLRRVAAVLRDNCSRPADLPARFGGEEFSMVLPSTSPGGARLFAEKVRRAIESLGIAHSGADTGGFLTVSIGAA
VLVPEDGQPSSRLVEVADAGLYEAKRNGRNQVVMAWPRA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=42.5925925925926, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=35.7142857142857, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=38.6740331491713, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786584, Length=182, Percent_Identity=33.5164835164835, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=33.9393939393939, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788381, Length=188, Percent_Identity=30.3191489361702, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787802, Length=168, Percent_Identity=33.9285714285714, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788085, Length=173, Percent_Identity=31.2138728323699, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787541, Length=173, Percent_Identity=31.2138728323699, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082007, Length=180, Percent_Identity=33.8888888888889, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787056, Length=176, Percent_Identity=32.9545454545455, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788956, Length=183, Percent_Identity=31.1475409836066, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081977, Length=181, Percent_Identity=29.2817679558011, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788394, Length=151, Percent_Identity=31.1258278145695, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081974, Length=110, Percent_Identity=29.0909090909091, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 39525; Mature: 39525

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQDVWGRAIKEASMQQPDNTAITAITDTPAANSYPVMVLLVDDQAMIGEAVRRALASE
CCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCCC
PDIDFHYCATPDDAVAVAERTRPTVILQDLVMPGVDGLTLVRRYRDNAATRDIPIIVLST
CCCCEEEECCCCHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEEEC
KEEAAMKSAAFSAGANDYLVKLPDSIELVARIRYHSRSYLNLLQRDEAYRALRQSQQQLL
CHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETNLELQRLTNSDGLTGLSNRRYFDEYLNAEWKRAQREQSQLALLMIDVDAFKAYNDTYG
HHCCHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHCEEEEEEEHHHHHHCCCCCC
HVAGDEVLRRVAAVLRDNCSRPADLPARFGGEEFSMVLPSTSPGGARLFAEKVRRAIESL
CCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHC
GIAHSGADTGGFLTVSIGAAVLVPEDGQPSSRLVEVADAGLYEAKRNGRNQVVMAWPRA
CCCCCCCCCCCEEEEEECEEEEECCCCCCHHHHHHHHHCCHHHHHHCCCCCEEEEECCC
>Mature Secondary Structure
MLNQDVWGRAIKEASMQQPDNTAITAITDTPAANSYPVMVLLVDDQAMIGEAVRRALASE
CCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCCC
PDIDFHYCATPDDAVAVAERTRPTVILQDLVMPGVDGLTLVRRYRDNAATRDIPIIVLST
CCCCEEEECCCCHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEEEC
KEEAAMKSAAFSAGANDYLVKLPDSIELVARIRYHSRSYLNLLQRDEAYRALRQSQQQLL
CHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETNLELQRLTNSDGLTGLSNRRYFDEYLNAEWKRAQREQSQLALLMIDVDAFKAYNDTYG
HHCCHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHCEEEEEEEHHHHHHCCCCCC
HVAGDEVLRRVAAVLRDNCSRPADLPARFGGEEFSMVLPSTSPGGARLFAEKVRRAIESL
CCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHC
GIAHSGADTGGFLTVSIGAAVLVPEDGQPSSRLVEVADAGLYEAKRNGRNQVVMAWPRA
CCCCCCCCCCCEEEEEECEEEEECCCCCCHHHHHHHHHCCHHHHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]