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The map label for this gene is blh [H]

Identifier: 73537424

GI number: 73537424

Start: 146867

End: 147763

Strand: Reverse

Name: blh [H]

Synonym: Reut_B3589

Alternate gene names: 73537424

Gene position: 147763-146867 (Counterclockwise)

Preceding gene: 73537427

Following gene: 73537423

Centisome position: 5.42

GC content: 61.65

Gene sequence:

>897_bases
ATGACACCGACCATGCCAAGCCCCTCGCAAATGGAGATCGAAGCCTTCTTCGATCCCGATACCTCTACGCTCAGTTACCT
CGTACTGGATCGCGCCACGCTGCAATGCGCATTGATCGACAGCGTGCTTGACTACGATCCCAAATCCGGCCGCACACGCA
CCGCCAGTGCGGACCGCCTTGTCGAGCGCGTGCAGTCGCTGCACGCCACCGTGCAGTGGATCGTGGAGACCCATGTGCAT
GCGGACCACCTGTCTGCCGCCCCCTACCTCAAGCGCAGGCTCGGCGGTCAGACCGCCATCGGCAGCCATATCACCACCGT
GCAGCAGGTCTTCGGCAAGCTTTTCAACAGTGGTGCAGACTTCGCGCGCGACGGGCATCAGTTTGACCGCCTGCTGAACG
ACGGCGATACCTTCAACATCGGCGGACTGCAAATGCGCGCCATGCACACGCCGGGGCATACGCCGGCATGCATGACTTAT
GTGGTCAGCGACGGCAACGATACCGCCGCATTCGTCGGCGACACCCTGTTCATGCCGGATTACGGCACTGCCCGGTGCGA
CTTCCCCGGCGGCGACGCGCGCACGCTCTACCGTTCCATCAACAAGGTGTTAAGCCTTCCACAAGACACTCGCCTGTACA
TGTGCCACGACTACCAGCCGGGCGGCAGGGAAATGAAATACATGACGACGGTCGCGGATGAGCGCGAGAACAACATCCAC
GTGCGTAACGGAATCAGCGAAGAGGAATTCGTCGCCATGCGCCAGGCGCGCGACGCCACGCTTTCCATGCCGACCCTGAT
ACTGCCTTCGGTCCAGGTGAACATGCGTGCGGGCGAATTGCCTCCGCCCGAGGACAACGGCGTGCGCTATCTGAAGATTC
CCCTCAACGCCCTCTGA

Upstream 100 bases:

>100_bases
AAAAAATCCGCAAAAAATCAATCACTTGGAGATCGAATTGGCATTGGCACGAGTTTTGAGTGGTGAATCGCAACGCTCTG
CTAACCACGGATAGACACAC

Downstream 100 bases:

>100_bases
GCCACCCGACCCAAGGAACAGACGACCATGCAACCCCGCGCCCTCACCAACGATCTTTCGGTCAGCCAGCAGATCGTTCC
AGACGATGTGCACGCTCTGG

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTPTMPSPSQMEIEAFFDPDTSTLSYLVLDRATLQCALIDSVLDYDPKSGRTRTASADRLVERVQSLHATVQWIVETHVH
ADHLSAAPYLKRRLGGQTAIGSHITTVQQVFGKLFNSGADFARDGHQFDRLLNDGDTFNIGGLQMRAMHTPGHTPACMTY
VVSDGNDTAAFVGDTLFMPDYGTARCDFPGGDARTLYRSINKVLSLPQDTRLYMCHDYQPGGREMKYMTTVADERENNIH
VRNGISEEEFVAMRQARDATLSMPTLILPSVQVNMRAGELPPPEDNGVRYLKIPLNAL

Sequences:

>Translated_298_residues
MTPTMPSPSQMEIEAFFDPDTSTLSYLVLDRATLQCALIDSVLDYDPKSGRTRTASADRLVERVQSLHATVQWIVETHVH
ADHLSAAPYLKRRLGGQTAIGSHITTVQQVFGKLFNSGADFARDGHQFDRLLNDGDTFNIGGLQMRAMHTPGHTPACMTY
VVSDGNDTAAFVGDTLFMPDYGTARCDFPGGDARTLYRSINKVLSLPQDTRLYMCHDYQPGGREMKYMTTVADERENNIH
VRNGISEEEFVAMRQARDATLSMPTLILPSVQVNMRAGELPPPEDNGVRYLKIPLNAL
>Mature_297_residues
TPTMPSPSQMEIEAFFDPDTSTLSYLVLDRATLQCALIDSVLDYDPKSGRTRTASADRLVERVQSLHATVQWIVETHVHA
DHLSAAPYLKRRLGGQTAIGSHITTVQQVFGKLFNSGADFARDGHQFDRLLNDGDTFNIGGLQMRAMHTPGHTPACMTYV
VSDGNDTAAFVGDTLFMPDYGTARCDFPGGDARTLYRSINKVLSLPQDTRLYMCHDYQPGGREMKYMTTVADERENNIHV
RNGISEEEFVAMRQARDATLSMPTLILPSVQVNMRAGELPPPEDNGVRYLKIPLNAL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=271, Percent_Identity=30.9963099630996, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17538952, Length=260, Percent_Identity=27.6923076923077, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221330176, Length=271, Percent_Identity=31.7343173431734, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 33070; Mature: 32939

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTMPSPSQMEIEAFFDPDTSTLSYLVLDRATLQCALIDSVLDYDPKSGRTRTASADRL
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VERVQSLHATVQWIVETHVHADHLSAAPYLKRRLGGQTAIGSHITTVQQVFGKLFNSGAD
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
FARDGHQFDRLLNDGDTFNIGGLQMRAMHTPGHTPACMTYVVSDGNDTAAFVGDTLFMPD
HHHCHHHHHHHHCCCCEEEECCEEEEEEECCCCCCCEEEEEEECCCCCEEEECCEEECCC
YGTARCDFPGGDARTLYRSINKVLSLPQDTRLYMCHDYQPGGREMKYMTTVADERENNIH
CCCEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEHHCCCCCEE
VRNGISEEEFVAMRQARDATLSMPTLILPSVQVNMRAGELPPPEDNGVRYLKIPLNAL
EECCCCHHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TPTMPSPSQMEIEAFFDPDTSTLSYLVLDRATLQCALIDSVLDYDPKSGRTRTASADRL
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VERVQSLHATVQWIVETHVHADHLSAAPYLKRRLGGQTAIGSHITTVQQVFGKLFNSGAD
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
FARDGHQFDRLLNDGDTFNIGGLQMRAMHTPGHTPACMTYVVSDGNDTAAFVGDTLFMPD
HHHCHHHHHHHHCCCCEEEECCEEEEEEECCCCCCCEEEEEEECCCCCEEEECCEEECCC
YGTARCDFPGGDARTLYRSINKVLSLPQDTRLYMCHDYQPGGREMKYMTTVADERENNIH
CCCEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEHHCCCCCEE
VRNGISEEEFVAMRQARDATLSMPTLILPSVQVNMRAGELPPPEDNGVRYLKIPLNAL
EECCCCHHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]