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The map label for this gene is blh [H]

Identifier: 73537423

GI number: 73537423

Start: 145163

End: 146839

Strand: Reverse

Name: blh [H]

Synonym: Reut_B3588

Alternate gene names: 73537423

Gene position: 146839-145163 (Counterclockwise)

Preceding gene: 73537424

Following gene: 73537421

Centisome position: 5.39

GC content: 66.19

Gene sequence:

>1677_bases
ATGCAACCCCGCGCCCTCACCAACGATCTTTCGGTCAGCCAGCAGATCGTTCCAGACGATGTGCACGCTCTGGCGGCCTT
CGGCTTTCGCTCGTTGATCTGCAACCGCCCGGATGGCGAAGGCCCTGACCAGCCAAACTTCCAGGAAATCGAACGCAAGG
CCTCCGCGCTCGGCCTGCAGGCACATTACCTGCCGGTGGAATCGGGCAAGGTCAGCGACGAACAGGCTCAGGCGTTCGGC
CAACTCCTGGACAGCCTGCCGAAACCCGTATTGGCCTACTGCCGCACCGGCACGCGCTCGGCGACGCTGTGGGCGCTGTC
GCAGTCCGTGATCAGGCCACTGCCGGACATCATCGAGCGGGCCGCGGCCGCCGGCTATGATCTAAAGGGCGTCGTGCGGC
GCATCGCCAATGGCGGCCGCACGCCCGTCGATGTTGCCGATGCCAGCCACGCTGTGGTCATCATTGGCGGCGGCGCCGCG
GGAATCGCCGTGGCGTCGAGCTTGCTGGCACGCAAGCCGGGGCTGGATATCGCCATCGTGGATCCGGCCGACATCCACTA
CTACCAGCCCGGCTGGACGCTGGTGGGCGGCGGCGTCTTCGAGCCAGCCCATACCGCGCGCACCATGGCTTCGGTGCTGC
CGCGGGGGGTGGCATGGATCAAGGCAGCCGTGGCAGCCTTCGAGCCCGAGCGCAATGCTGTCATCCTTGATGGGTGCCGC
GTGGTGAAGTACGAACAACTGATAGTGTGCCCAGGGCTCAAGCTGGATTGGGACGCCATCGAAGGGCTGCCCGAAACGCT
GGGCCGCAACGGCGTGACTTCCAACTACCGCTACGACCTCGCTCCGTACACCTGGAACCTCGTGCGCGAGTTGACCCGCA
AGGGCGGCGGCAAAGCGCTTTTCACGCAGCCGCCCATGCCGATCAAGTGCGCCGGCGCGCCGCAGAAAGCCATGTACCTG
TCTGCCGATGCCTGGCGCCGCGCCGGCATTCTCGATCGCGTCGACATAGATTTCTGCAATGCAGGCAACGTGCTGTTCGG
TGTGGCCGACTACGTGCCGGCGCTGATGCAGTACGTCGAGCGCTATGGCATTGCACTGAATTTCGGCGAGACGCTGGTGA
AAGTGGATGGCGCCGCACGCCGGGCAACGTTCCGCCTGGCCGCGGATGGGGGCGATCCGAAACTGGTCGAGCGCGAGTTC
GACATGCTCCACGCGGTGCCGCCCCAGAAGGCGCCCGATTTCATTCGCGTCAGCCCGCTGGCCGATGCCGCCGGCTGGAT
CGACGCCGATCCGGCAACGCTGCGTCACAAGCGCTTCGACAATGTCTTTGGGTTAGGCGACGCCGGCAACATGCCCAATG
CCAAGACGGCCGCCGCGGCGCGCAAGCAGGCGCCAGTCGTCGCGCACAACGTCCTCGCCACGCGCGGCGAGGCCACGGGA
GAAGCCCGCTACGACGGCTACGGCTCCTGCCCCCTGACCGTGGAACGCGGCAAGATCGTCCTGGCCGAGTTCACCTACGG
CGGCAAGGTCGCACCGAGCTTTCCGGGCTGGCTCATCGACGGCACGCGGCCTTCGCGGCTGGCATGGTGGCTCAAAGAGC
GGATTCTGCCGCCGCTCTACTGGCAGGGGATGCTGAAAGGACGCGAATGGCTCGCGACACCCGAGTTGCAGGGATAA

Upstream 100 bases:

>100_bases
GCGTGCGGGCGAATTGCCTCCGCCCGAGGACAACGGCGTGCGCTATCTGAAGATTCCCCTCAACGCCCTCTGAGCCACCC
GACCCAAGGAACAGACGACC

Downstream 100 bases:

>100_bases
CACCCGAAGCTGCCCGAACTGTTGTACCCGGTTGCGGTTATCCGGTTCTACCCCCTTCCGGGCAAGACTTGTCTACCGTC
GGCCCAAATGGCACACCATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MQPRALTNDLSVSQQIVPDDVHALAAFGFRSLICNRPDGEGPDQPNFQEIERKASALGLQAHYLPVESGKVSDEQAQAFG
QLLDSLPKPVLAYCRTGTRSATLWALSQSVIRPLPDIIERAAAAGYDLKGVVRRIANGGRTPVDVADASHAVVIIGGGAA
GIAVASSLLARKPGLDIAIVDPADIHYYQPGWTLVGGGVFEPAHTARTMASVLPRGVAWIKAAVAAFEPERNAVILDGCR
VVKYEQLIVCPGLKLDWDAIEGLPETLGRNGVTSNYRYDLAPYTWNLVRELTRKGGGKALFTQPPMPIKCAGAPQKAMYL
SADAWRRAGILDRVDIDFCNAGNVLFGVADYVPALMQYVERYGIALNFGETLVKVDGAARRATFRLAADGGDPKLVEREF
DMLHAVPPQKAPDFIRVSPLADAAGWIDADPATLRHKRFDNVFGLGDAGNMPNAKTAAAARKQAPVVAHNVLATRGEATG
EARYDGYGSCPLTVERGKIVLAEFTYGGKVAPSFPGWLIDGTRPSRLAWWLKERILPPLYWQGMLKGREWLATPELQG

Sequences:

>Translated_558_residues
MQPRALTNDLSVSQQIVPDDVHALAAFGFRSLICNRPDGEGPDQPNFQEIERKASALGLQAHYLPVESGKVSDEQAQAFG
QLLDSLPKPVLAYCRTGTRSATLWALSQSVIRPLPDIIERAAAAGYDLKGVVRRIANGGRTPVDVADASHAVVIIGGGAA
GIAVASSLLARKPGLDIAIVDPADIHYYQPGWTLVGGGVFEPAHTARTMASVLPRGVAWIKAAVAAFEPERNAVILDGCR
VVKYEQLIVCPGLKLDWDAIEGLPETLGRNGVTSNYRYDLAPYTWNLVRELTRKGGGKALFTQPPMPIKCAGAPQKAMYL
SADAWRRAGILDRVDIDFCNAGNVLFGVADYVPALMQYVERYGIALNFGETLVKVDGAARRATFRLAADGGDPKLVEREF
DMLHAVPPQKAPDFIRVSPLADAAGWIDADPATLRHKRFDNVFGLGDAGNMPNAKTAAAARKQAPVVAHNVLATRGEATG
EARYDGYGSCPLTVERGKIVLAEFTYGGKVAPSFPGWLIDGTRPSRLAWWLKERILPPLYWQGMLKGREWLATPELQG
>Mature_558_residues
MQPRALTNDLSVSQQIVPDDVHALAAFGFRSLICNRPDGEGPDQPNFQEIERKASALGLQAHYLPVESGKVSDEQAQAFG
QLLDSLPKPVLAYCRTGTRSATLWALSQSVIRPLPDIIERAAAAGYDLKGVVRRIANGGRTPVDVADASHAVVIIGGGAA
GIAVASSLLARKPGLDIAIVDPADIHYYQPGWTLVGGGVFEPAHTARTMASVLPRGVAWIKAAVAAFEPERNAVILDGCR
VVKYEQLIVCPGLKLDWDAIEGLPETLGRNGVTSNYRYDLAPYTWNLVRELTRKGGGKALFTQPPMPIKCAGAPQKAMYL
SADAWRRAGILDRVDIDFCNAGNVLFGVADYVPALMQYVERYGIALNFGETLVKVDGAARRATFRLAADGGDPKLVEREF
DMLHAVPPQKAPDFIRVSPLADAAGWIDADPATLRHKRFDNVFGLGDAGNMPNAKTAAAARKQAPVVAHNVLATRGEATG
EARYDGYGSCPLTVERGKIVLAEFTYGGKVAPSFPGWLIDGTRPSRLAWWLKERILPPLYWQGMLKGREWLATPELQG

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI10864011, Length=406, Percent_Identity=36.9458128078818, Blast_Score=295, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI115534373, Length=345, Percent_Identity=36.5217391304348, Blast_Score=237, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17539680, Length=434, Percent_Identity=32.258064516129, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24657386, Length=389, Percent_Identity=37.5321336760925, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24657391, Length=389, Percent_Identity=37.5321336760925, Blast_Score=259, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 60219; Mature: 60219

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPRALTNDLSVSQQIVPDDVHALAAFGFRSLICNRPDGEGPDQPNFQEIERKASALGLQ
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCE
AHYLPVESGKVSDEQAQAFGQLLDSLPKPVLAYCRTGTRSATLWALSQSVIRPLPDIIER
EEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AAAAGYDLKGVVRRIANGGRTPVDVADASHAVVIIGGGAAGIAVASSLLARKPGLDIAIV
HHHCCCCHHHHHHHHHCCCCCCEEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEE
DPADIHYYQPGWTLVGGGVFEPAHTARTMASVLPRGVAWIKAAVAAFEPERNAVILDGCR
CCCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCE
VVKYEQLIVCPGLKLDWDAIEGLPETLGRNGVTSNYRYDLAPYTWNLVRELTRKGGGKAL
EEEEEEEEECCCCCCCHHHHCCCHHHHCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCEE
FTQPPMPIKCAGAPQKAMYLSADAWRRAGILDRVDIDFCNAGNVLFGVADYVPALMQYVE
EECCCCCEEECCCCCCEEEEEHHHHHHCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHH
RYGIALNFGETLVKVDGAARRATFRLAADGGDPKLVEREFDMLHAVPPQKAPDFIRVSPL
HCCEEEECCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEECCC
ADAAGWIDADPATLRHKRFDNVFGLGDAGNMPNAKTAAAARKQAPVVAHNVLATRGEATG
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCC
EARYDGYGSCPLTVERGKIVLAEFTYGGKVAPSFPGWLIDGTRPSRLAWWLKERILPPLY
CCCCCCCCCCCEEEECCEEEEEEECCCCEECCCCCCEEEECCCHHHHHHHHHHHCCCCHH
WQGMLKGREWLATPELQG
HHHHHCCCCEECCCCCCC
>Mature Secondary Structure
MQPRALTNDLSVSQQIVPDDVHALAAFGFRSLICNRPDGEGPDQPNFQEIERKASALGLQ
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCE
AHYLPVESGKVSDEQAQAFGQLLDSLPKPVLAYCRTGTRSATLWALSQSVIRPLPDIIER
EEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AAAAGYDLKGVVRRIANGGRTPVDVADASHAVVIIGGGAAGIAVASSLLARKPGLDIAIV
HHHCCCCHHHHHHHHHCCCCCCEEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEE
DPADIHYYQPGWTLVGGGVFEPAHTARTMASVLPRGVAWIKAAVAAFEPERNAVILDGCR
CCCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCE
VVKYEQLIVCPGLKLDWDAIEGLPETLGRNGVTSNYRYDLAPYTWNLVRELTRKGGGKAL
EEEEEEEEECCCCCCCHHHHCCCHHHHCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCEE
FTQPPMPIKCAGAPQKAMYLSADAWRRAGILDRVDIDFCNAGNVLFGVADYVPALMQYVE
EECCCCCEEECCCCCCEEEEEHHHHHHCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHH
RYGIALNFGETLVKVDGAARRATFRLAADGGDPKLVEREFDMLHAVPPQKAPDFIRVSPL
HCCEEEECCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEECCC
ADAAGWIDADPATLRHKRFDNVFGLGDAGNMPNAKTAAAARKQAPVVAHNVLATRGEATG
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCC
EARYDGYGSCPLTVERGKIVLAEFTYGGKVAPSFPGWLIDGTRPSRLAWWLKERILPPLY
CCCCCCCCCCCEEEECCEEEEEEECCCCEECCCCCCEEEECCCHHHHHHHHHHHCCCCHH
WQGMLKGREWLATPELQG
HHHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]