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The map label for this gene is mmgC [H]

Identifier: 73537377

GI number: 73537377

Start: 90473

End: 91642

Strand: Reverse

Name: mmgC [H]

Synonym: Reut_B3542

Alternate gene names: 73537377

Gene position: 91642-90473 (Counterclockwise)

Preceding gene: 73537379

Following gene: 73537376

Centisome position: 3.36

GC content: 63.33

Gene sequence:

>1170_bases
ATGTTTGCAGATCAGGATCAAGACCAGCTTTTCCCGGAAATCCGCGAAGCCGTACGCGACCTTTGCGCGGGTTTCGATTC
GGCCTACTGGCAGCGCATTGAAGAACAGAACGGTTTTCCCGAGGAATTCGTTCAGGCGCTTACCCACGCGGGCTGGCTGT
CGGCCCTGATCCCCGAGGCCTACGGCGGTTCGGGCCTGTCGCTGACGGCCGCCTCGGTCATCATGGAAGAAATCAACCGC
AACGGCGGCAACTCCGGCGCCTGCCACGGCCAGATGTACGTGATGGGCTGCCTGCTGCGCCACGGTTCGGAAGAGCAAAA
GAAGCGCTGGCTGCCGGGCATCGCCTCGGGCGAACTGCGCATGCAGTCGATGGCTGTGACCGAGCCGACCACCGGCACCG
ACACCACCAAACTCAAGACCACTGCCGTGCGCAAGGGCGACAAGTACGTCGTCAACGGCTCGAAGGTGTGGATTTCGCGC
GTGCAGCACTCGGACCTGATGCTGCTGCTGGCCCGCACCACGCCGCTCGACCAGGTCAAGCGCAAGTCCGAGGGCCTGTC
GGTGTTCGTGGTCGACCTGCGTGAAGCCATCGGCAAGGGCCTGACAGTTCGGCCGATCCGCAACATGGTCAACCACGAGA
CCAACGAACTGTTCTTCGACAACCTCGAAGTGCCGGCCGAAAACCTGATCGGCGAGGAAGGCAAGGGCCTCAAGTACATC
CTCGACGGCATGAACGCCGAGCGCATCCTGATCGCCGCCGAGTGCATCGGCGATGGCTACTGGTTCGTCGAGCGCGCGAG
CAACTATGCACGCGAGCGCATTGTGTTCGACCGCCCGATCGGCCAGAACCAGGGCATTCAGTTCCCGATCGCACGCTCCT
ACGTCAACGTCGAAGCCGCCAGCCTGATGCGCTACAAGGCTGCAGCGCTGTTCGACGCCGGCAAGCCGTGCGGCAAGGAA
GCCAACATCTCCAAGCTGCTCGCCGCCGATGCATCGTGGGAAGCGGCCAACGTCTGCCTGCAGACGCACGGCGGCTTCGG
CTTCGCGGCCGAGTACGACATCGAGCGCAAGTTCCGCGAGACCCGCCTGTACCAGGTCGCACCGATCTCGACCAACCTGA
TCCTGTCCTACGTGGCCGAGCACGTGCTCGAGCTGCCGCGTTCGTTCTGA

Upstream 100 bases:

>100_bases
GCACCTAAGCCGCACCTAAGCCGCTCTTTCGCAAATCCGAATTTCAGGCCAAAGGGCTGTCGGGAATAATGGCCCCATTC
AAATCGACCGGGCCTACCCC

Downstream 100 bases:

>100_bases
GGCCGCGCATGACTGCATCTACGCCCAACGGCATCCGGCCGCTCGACGGCATCCGCGTGGTGTCGCTCGAACACGCGGTC
GCGGCCCCTTTCGCCACGCG

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MFADQDQDQLFPEIREAVRDLCAGFDSAYWQRIEEQNGFPEEFVQALTHAGWLSALIPEAYGGSGLSLTAASVIMEEINR
NGGNSGACHGQMYVMGCLLRHGSEEQKKRWLPGIASGELRMQSMAVTEPTTGTDTTKLKTTAVRKGDKYVVNGSKVWISR
VQHSDLMLLLARTTPLDQVKRKSEGLSVFVVDLREAIGKGLTVRPIRNMVNHETNELFFDNLEVPAENLIGEEGKGLKYI
LDGMNAERILIAAECIGDGYWFVERASNYARERIVFDRPIGQNQGIQFPIARSYVNVEAASLMRYKAAALFDAGKPCGKE
ANISKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRETRLYQVAPISTNLILSYVAEHVLELPRSF

Sequences:

>Translated_389_residues
MFADQDQDQLFPEIREAVRDLCAGFDSAYWQRIEEQNGFPEEFVQALTHAGWLSALIPEAYGGSGLSLTAASVIMEEINR
NGGNSGACHGQMYVMGCLLRHGSEEQKKRWLPGIASGELRMQSMAVTEPTTGTDTTKLKTTAVRKGDKYVVNGSKVWISR
VQHSDLMLLLARTTPLDQVKRKSEGLSVFVVDLREAIGKGLTVRPIRNMVNHETNELFFDNLEVPAENLIGEEGKGLKYI
LDGMNAERILIAAECIGDGYWFVERASNYARERIVFDRPIGQNQGIQFPIARSYVNVEAASLMRYKAAALFDAGKPCGKE
ANISKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRETRLYQVAPISTNLILSYVAEHVLELPRSF
>Mature_389_residues
MFADQDQDQLFPEIREAVRDLCAGFDSAYWQRIEEQNGFPEEFVQALTHAGWLSALIPEAYGGSGLSLTAASVIMEEINR
NGGNSGACHGQMYVMGCLLRHGSEEQKKRWLPGIASGELRMQSMAVTEPTTGTDTTKLKTTAVRKGDKYVVNGSKVWISR
VQHSDLMLLLARTTPLDQVKRKSEGLSVFVVDLREAIGKGLTVRPIRNMVNHETNELFFDNLEVPAENLIGEEGKGLKYI
LDGMNAERILIAAECIGDGYWFVERASNYARERIVFDRPIGQNQGIQFPIARSYVNVEAASLMRYKAAALFDAGKPCGKE
ANISKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRETRLYQVAPISTNLILSYVAEHVLELPRSF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=30.7486631016043, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4557233, Length=388, Percent_Identity=29.8969072164948, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI226958412, Length=347, Percent_Identity=30.2593659942363, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI226958414, Length=342, Percent_Identity=30.4093567251462, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI21361497, Length=357, Percent_Identity=28.8515406162465, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI4557231, Length=349, Percent_Identity=30.6590257879656, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI187960098, Length=349, Percent_Identity=30.6590257879656, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI76496475, Length=344, Percent_Identity=30.5232558139535, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI4557235, Length=344, Percent_Identity=30.5232558139535, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI7656849, Length=357, Percent_Identity=29.4117647058824, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI4501857, Length=329, Percent_Identity=31.0030395136778, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI38505218, Length=337, Percent_Identity=26.7062314540059, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI7669494, Length=325, Percent_Identity=26.4615384615385, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4503943, Length=325, Percent_Identity=26.4615384615385, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI48976061, Length=282, Percent_Identity=26.5957446808511, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI211971008, Length=282, Percent_Identity=26.5957446808511, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI87081958, Length=382, Percent_Identity=27.7486910994764, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1786223, Length=387, Percent_Identity=27.6485788113695, Blast_Score=144, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17534899, Length=342, Percent_Identity=34.2105263157895, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=32.1989528795811, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=345, Percent_Identity=33.3333333333333, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=29.144385026738, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17506239, Length=344, Percent_Identity=29.9418604651163, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17508101, Length=337, Percent_Identity=30.8605341246291, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=28.4507042253521, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=296, Percent_Identity=32.4324324324324, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17505929, Length=341, Percent_Identity=29.3255131964809, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17533517, Length=358, Percent_Identity=27.6536312849162, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=341, Percent_Identity=27.5659824046921, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71985192, Length=316, Percent_Identity=28.1645569620253, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI32563615, Length=222, Percent_Identity=31.981981981982, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17534353, Length=359, Percent_Identity=27.5766016713092, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=27.2357723577236, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982178, Length=223, Percent_Identity=28.6995515695067, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562446, Length=269, Percent_Identity=27.5092936802974, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356377, Length=359, Percent_Identity=32.3119777158774, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=31.7333333333333, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24646207, Length=348, Percent_Identity=29.5977011494253, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21355753, Length=344, Percent_Identity=29.9418604651163, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI281363737, Length=360, Percent_Identity=27.7777777777778, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24660351, Length=374, Percent_Identity=29.6791443850267, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19920834, Length=310, Percent_Identity=29.6774193548387, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43224; Mature: 43224

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00073 ACYL_COA_DH_2 ; PS00777 GLYCOSYL_HYDROL_F11_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFADQDQDQLFPEIREAVRDLCAGFDSAYWQRIEEQNGFPEEFVQALTHAGWLSALIPEA
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
YGGSGLSLTAASVIMEEINRNGGNSGACHGQMYVMGCLLRHGSEEQKKRWLPGIASGELR
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEE
MQSMAVTEPTTGTDTTKLKTTAVRKGDKYVVNGSKVWISRVQHSDLMLLLARTTPLDQVK
EHEEEECCCCCCCCCCEEEHHHHCCCCEEEECCCHHEEHHHCCCCEEEEEECCCCHHHHH
RKSEGLSVFVVDLREAIGKGLTVRPIRNMVNHETNELFFDNLEVPAENLIGEEGKGLKYI
HHCCCCEEEEEEHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCCCHHHH
LDGMNAERILIAAECIGDGYWFVERASNYARERIVFDRPIGQNQGIQFPIARSYVNVEAA
CCCCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
SLMRYKAAALFDAGKPCGKEANISKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRE
HHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCHHHHEEEEECCCCCEEEECCHHHHHHH
TRLYQVAPISTNLILSYVAEHVLELPRSF
HHCEEEECCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFADQDQDQLFPEIREAVRDLCAGFDSAYWQRIEEQNGFPEEFVQALTHAGWLSALIPEA
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
YGGSGLSLTAASVIMEEINRNGGNSGACHGQMYVMGCLLRHGSEEQKKRWLPGIASGELR
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEE
MQSMAVTEPTTGTDTTKLKTTAVRKGDKYVVNGSKVWISRVQHSDLMLLLARTTPLDQVK
EHEEEECCCCCCCCCCEEEHHHHCCCCEEEECCCHHEEHHHCCCCEEEEEECCCCHHHHH
RKSEGLSVFVVDLREAIGKGLTVRPIRNMVNHETNELFFDNLEVPAENLIGEEGKGLKYI
HHCCCCEEEEEEHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCCCHHHH
LDGMNAERILIAAECIGDGYWFVERASNYARERIVFDRPIGQNQGIQFPIARSYVNVEAA
CCCCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
SLMRYKAAALFDAGKPCGKEANISKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRE
HHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCHHHHEEEEECCCCCEEEECCHHHHHHH
TRLYQVAPISTNLILSYVAEHVLELPRSF
HHCEEEECCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]