Click here to switch to the map view.

The map label for this gene is spyA

Identifier: 71910164

GI number: 71910164

Start: 357724

End: 358476

Strand: Reverse

Name: spyA

Synonym: M5005_Spy_0351

Alternate gene names: NA

Gene position: 358476-357724 (Counterclockwise)

Preceding gene: 71910167

Following gene: 71910153

Centisome position: 19.5

GC content: 50.46

Gene sequence:

>753_bases
ATGCTAAAAAAGCGCTATCAACTGGCTATTGTCCTTCTTCTTAGCTGTTTTAGTCTGATCTGGCAAACTGAGGGCTTGGT
CGAGCTTTTTGTCTGTGAGCACTATGAGCGGGCGGTTTGTGAGGGGACGCCTGCTTATTTTACCTTTTCGGATCAAAAGG
GCGCTGAGACACTGATTAAAAAGCGATGGGGCAAGGGTCTCATCTACCCAAGGGCTGAGCAAGAGGCGATGGCTGCTTAT
ACCTGTCAGCAGGCAGGCCCTATCAACACCAGCCTAGACAAAGCCAAAGGTGAGCTCAGCCAACTCACGCCTGAGCTAAG
GGATCAGGTGGCCCAGCTCGATGCTGCGACTCACCGGCTAGTCATCCCGTGGAACATTGTAGTATACCGCTATGTATACG
AGACGTTTTTGCGTGATATCGGTGTTTCACATGCTGATCTCACGTCTTACTACCGTAACCATCAGTTTGACCCTCATATC
CTTTGTAAGATCAAGCTTGGTACACGCTACACCAAGCACAGTTTTATGAGCACGACAGCCTTGAAAAACGGCGCCATGAC
CCATCGACCGGTGGAGGTGCGCATCTGTGTCAAAAAAGGGGCCAAGGCAGCCTTTGTCGAGCCTTATTCGGCTGTGCCTT
CAGAGGTTGAGCTCTTGTTTCCAAGAGGCTGTCAGCTGGAGGTCGTTGGAGCTTACGTGTCACAGGACCAAAAAAAGCTC
CACATAGAAGCGTATTTCAAGGGCAGTTTGTGA

Upstream 100 bases:

>100_bases
TGACAAAAAGATTAGCCTGTCTGAGAAACTGGTGGTGTCAAGAGCTAGCCAAAAGGTCTAGGGGAAGGGTCAGCCTTTTG
GGCTGGTGTCAGGGGGAACT

Downstream 100 bases:

>100_bases
CGGCCTCAACACCGATCGCCAAAAAAAGGACTCCATGTCCTTTTTTTTGACGTTCTGATGCTCAAAAAAGCCTCGCATAG
CAGCAGACTAACGGGCTTTG

Product: C3 family ADP-ribosyltransferase

Products: NA

Alternate protein names: EDIN [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTPAYFTFSDQKGAETLIKKRWGKGLIYPRAEQEAMAAY
TCQQAGPINTSLDKAKGELSQLTPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVELLFPRGCQLEVVGAYVSQDQKKL
HIEAYFKGSL

Sequences:

>Translated_250_residues
MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTPAYFTFSDQKGAETLIKKRWGKGLIYPRAEQEAMAAY
TCQQAGPINTSLDKAKGELSQLTPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVELLFPRGCQLEVVGAYVSQDQKKL
HIEAYFKGSL
>Mature_250_residues
MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTPAYFTFSDQKGAETLIKKRWGKGLIYPRAEQEAMAAY
TCQQAGPINTSLDKAKGELSQLTPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVELLFPRGCQLEVVGAYVSQDQKKL
HIEAYFKGSL

Specific function: Inhibits terminal differentiation of cultured mouse keratinocytes. In culture, inhibits also the differentiation of human keratinocytes. Probable ADP-ribosyltransferase [H]

COG id: COG5585

COG function: function code T; NAD+--asparagine ADP-ribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To ADP-ribosyltransferase C3 of Clostridium [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003540
- InterPro:   IPR016678 [H]

Pfam domain/function: PF03496 Binary_toxA [H]

EC number: NA

Molecular weight: Translated: 28418; Mature: 28418

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTPAYFTFSDQKGAETLIK
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHH
KRWGKGLIYPRAEQEAMAAYTCQQAGPINTSLDKAKGELSQLTPELRDQVAQLDAATHRL
HHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCEE
VIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHILCKIKLGTRYTKHSFMSTTA
EECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
LKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVELLFPRGCQLEVVGAYVSQDQKKL
HCCCCCCCCCEEEEEEECCCCCEEEECCHHCCCCCEEEECCCCCEEEEEEHHHCCCCCEE
HIEAYFKGSL
EEEEEEECCC
>Mature Secondary Structure
MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTPAYFTFSDQKGAETLIK
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHH
KRWGKGLIYPRAEQEAMAAYTCQQAGPINTSLDKAKGELSQLTPELRDQVAQLDAATHRL
HHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCEE
VIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHILCKIKLGTRYTKHSFMSTTA
EECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
LKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVELLFPRGCQLEVVGAYVSQDQKKL
HCCCCCCCCCEEEEEEECCCCCEEEECCHHCCCCCEEEECCCCCEEEEEEHHHCCCCCEE
HIEAYFKGSL
EEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1993048; 2256941 [H]