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The map label for this gene is fhuG [H]

Identifier: 71910135

GI number: 71910135

Start: 327182

End: 328108

Strand: Reverse

Name: fhuG [H]

Synonym: M5005_Spy_0321

Alternate gene names: 71910135

Gene position: 328108-327182 (Counterclockwise)

Preceding gene: 71910136

Following gene: 71910112

Centisome position: 17.85

GC content: 39.16

Gene sequence:

>927_bases
TTGTCCCTTGGAGAATCTCATCTATCTTTTTTGGACCTTGTCCATGTGTTTTTGGGAAAATCTAGCCATGCCATATCTTT
CATCGTTATTAACATTCGTCTGCCAAGAATTCTAGCTGCTTGTCTAGGAGGCGGTTCTCTTGCTTTATCAGGGCTATTAT
TACAACGTTTAACACGAAATCCCTTAGCTGACTCTGGTGTATTAGGTATTACTATAGGAGCAGGTATCTCTTTGGCTATT
GTGGTCTCCTTTTCTTTCTTTGAGCAAGCTCATATCAGCCATTACTTGCCTTTATTTGCCATGCTTGGTGCTATTGTAAC
AACCTTTAGCGTTTATTGGCTATCTTTGACAAAACAAGGACAAATTGATCCTACACGGTTAATTCTTACTGGTGTAGCTG
TTACTACCATGCTTTCAAGTCTAATGGTTGCTCTTGTTGGTCATATTAATCGCTACAAAGTCGATTTGGTCATCAATTGG
CTTAGCGGCCAATTGATAGGAGACGACTGGCCTACTCTGAGTGTCATCGCTCCTTTGTTATTGTGTTTTTGGCTATTGAC
TTATAGTCAAGCCCATTTCCTTAATATTATGGGATTAGCTGATAATACTGCTATTGGGCTAGGACTCCCTTTAAACCGTA
AGCGTCGTTTGATACTTGTCTTAGCAGCTGGCTTAGGTGCTTTGAGTGTTCTTTTGGTTGGTAATATTAGTTTTATCGGC
TTAATAGCTGGACACTTTAGTACATACTTGGTAGGGAGTAATCATAAAATAACAATACCCATTAGTATTTTAATCGGAAT
GATCCTACTTCTTGTTGCAGATACAGTAGGACGAGTCTATCTGGTTGGCAGTAATATCCAGACAGGGATTTTAGTGTCGC
TTATCGGAGCCCCTTATTTTCTTTACTTAATGGCAAAAACAAAATAA

Upstream 100 bases:

>100_bases
GGTTAATAAGAAGAGGAGGCCGCTATTGAAATCTCAAAGACACCTTTTAAGGTTATATACTAGCCTGATCCTGCTACTTG
TAAGTCTTATGGGATTAGCT

Downstream 100 bases:

>100_bases
AAGCACTCAAAAAGCTAAGAACAGTCCTTGTTCCTAGCTCTTTTCTATGGTGCTATAAAGGTTAAACTTTCTTTATCCAA
GGTCATTAGCAGCTGGTATG

Product: ferrichrome transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSLGESHLSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADSGVLGITIGAGISLAI
VVSFSFFEQAHISHYLPLFAMLGAIVTTFSVYWLSLTKQGQIDPTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINW
LSGQLIGDDWPTLSVIAPLLLCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFIG
LIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGAPYFLYLMAKTK

Sequences:

>Translated_308_residues
MSLGESHLSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADSGVLGITIGAGISLAI
VVSFSFFEQAHISHYLPLFAMLGAIVTTFSVYWLSLTKQGQIDPTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINW
LSGQLIGDDWPTLSVIAPLLLCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFIG
LIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGAPYFLYLMAKTK
>Mature_307_residues
SLGESHLSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADSGVLGITIGAGISLAIV
VSFSFFEQAHISHYLPLFAMLGAIVTTFSVYWLSLTKQGQIDPTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWL
SGQLIGDDWPTLSVIAPLLLCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFIGL
IAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGAPYFLYLMAKTK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=290, Percent_Identity=33.1034482758621, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786805, Length=306, Percent_Identity=34.9673202614379, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786347, Length=307, Percent_Identity=32.2475570032573, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=31.8181818181818, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1790741, Length=286, Percent_Identity=32.1678321678322, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786804, Length=248, Percent_Identity=31.8548387096774, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32984; Mature: 32853

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGESHLSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRN
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHCC
PLADSGVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAIVTTFSVYWLSLTKQG
CCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
QIDPTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEECCCCCHHHHHHHHH
LCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFIG
HHHHHHHHCCHHHEEEEECCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHHHCCHHHHH
LIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGAPYF
HHHHHHHHEEECCCCEEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCEE
LYLMAKTK
EEEEEECC
>Mature Secondary Structure 
SLGESHLSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRN
CCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHCC
PLADSGVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAIVTTFSVYWLSLTKQG
CCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
QIDPTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEECCCCCHHHHHHHHH
LCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFIG
HHHHHHHHCCHHHEEEEECCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHHHCCHHHHH
LIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGAPYF
HHHHHHHHEEECCCCEEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCEE
LYLMAKTK
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]