Click here to switch to the map view.

The map label for this gene is gacS [H]

Identifier: 71908367

GI number: 71908367

Start: 2950191

End: 2954018

Strand: Reverse

Name: gacS [H]

Synonym: Daro_2754

Alternate gene names: 71908367

Gene position: 2954018-2950191 (Counterclockwise)

Preceding gene: 71908369

Following gene: 71908366

Centisome position: 65.63

GC content: 58.52

Gene sequence:

>3828_bases
ATGTCGTTTTTGTCAAAGATGGCCTCCCCGTCGTCAGCCCTGAGTTTCCGCAAGCAGATCATCCGGCCAGTGCTGGTCTC
CACCATTGCGCTGGCCATCCTGATATTGCTTAGCTTCGCGGCCTATCTGGATTGGCGCGAAAGGGAGCGCACCGCGCTCG
CAACCCAGCAGGTCGAGCGCATCTGGCAGGGTATGGTCGATAATAATGGCCGCTACTTGCGCTGGATGGCGACACAGGTC
GCCAATGACCACCGGTTTGTCGAAGCAATGCAGCGGGGCGATCGGGACGCTTTGCTGGCCTTGGCAGGACCCAGGTACCG
CGAATTGCATGCCCAGTTTGACCTTAGTCACTGGTATTTCATTACGCCAGACCGCAAGGTGCTTCTCCGTGTCCATGATC
CTGAGCGGAGTGGGGACGAGGTGCGCCGCAAAGGCTTGCTGGATGCCGAGGCGAGCGGCCAGATGACGACCGGCCTCGAA
CTTGGCACAACTTCCGTTTTTACGCTCAGGCAGGTCATGCCGTGGCGTGTCAATGGCAATGTGATCGGCTATGTCGAGAT
GGGCATGGAGGTTGAATCCTTTGCCCGCGAGATCAAGCGCCTGACCGGTCTGGATGTGCTGACGGCGGTGCATAAGGCCT
ATTCATCAGCCGAAGCTTTCGCTAATGGCAAGAAGGCCTTTGGCCTATCGGGAAACTGGGGTGACCATGCCGAGATTGCC
CTGCTCAGCCAGTCATTCCCTGGGGTTCCGGCATCGCTGATCGCCTCTTGGCAGGGGTTTGTCCGGGGTAGTGACCCAGG
CGTCTTCGACGTGATCAAGGGCGAGCGTATCTGGTCGGCAAAACTGATTGCCTTGCTGGATAACGATCAGCATCCGGTCG
CCTCAATGGCCATTTTGCGGGATATCGCGGCTGATCGGGTATCGCGTACCCAGTTGCTCTTTTTTGTTGGCACGGGGTCC
GCGCTTTTCATCGTGCTGCTGATGCTTGCCCTCCACCGTCGCGTTGGGAGCGTCGAGCAACATGTCATCCAGGCCAATGA
CGCACTTGCGGCATCCAATCAACGCTTCCGCGATTTCTCGGAGAGCTCGGCTGACTGGCTCTGGGAAACGGACGCCAATC
TTCGTTTCTCTTATTTTTCAGAAAACCTGCAGCGCATTTGCGGTATCGACCCCCAAAAGGTCTTGGGCAAGGCCCGAAGC
GAGTTGTGGCTTAACGATGAGATCAATAAACCGGACGCGCTGGCGGGGCACCTGGCTGTTCTTGAAAACCGGGAAGCGTT
TCGTGATTTTGAATACTGTCTCCTGAATGACCGGGGGGAACACCTGTGGCTTCTCGCCAGCGGTATTCCGTACTTCGACA
AGGAGGGGCACTTTGCGGGCTATCGAGGTATCGGACAAAACATCACGGTTCGGAAAGATCTGGAATTGGCCGCTGAGAAA
TCGGCCAAGCTGCTGCGGGAGGCCGTTGAGAACGTCTCGGTCGGCTTCACGATCTACGATGAAGAAGACCGGCTGGTTAT
TTGCAACGAAACCTATCTGGATATTTATTCCGACAGCAGCGACCTGATCGTGCCTGGCATGCACTTCGCGGACATCATTC
GCAAAGGTGCCGAGCGCGGCCAGTATCCTGAAGCTCAAGGCGACATCGACGGCTGGGTCTGCAGTCGTGTGGCACAGCAC
CAGCATCCGGACGGGCTGGCCATTGAGCAGGAGCTGAATGATGGGCGCTGGCTGCTGATTATCGAAAATCGCACCCCCAG
TGGCTACATCGTCGGCAACCGGATCGACATTACTGCCCGCAAGCAGGCTGAAAGGCAGTTGCTTTTGTTGTCCATGGCGG
TCGAGCAGAGTACCGAGGGCATTCTTATCACCGATGTCGATGCCAATATCGAGTATGTCAATGAGGCTTTCGTCCGTATC
TCGGGCTTCAGTCGCGAAGAGGCGATTGGGCAGACGCCGCGCATCCTGGATTCCGGTCTGACGCCGAGAGAAACCTATGC
CGAAATGTGGGCGGTGCTGTCGCGTGGCCAGCTTTGGCAGGGCGAGCTGATCAACAAGCGCAAGAGCGGTGAAATCTACA
CCGAACGCCTGACGATCATGCCCATGCGGCAGGATGGTCGAGTCACCCACTACGTTGCAGTCAAGGAAGACGTCACCGAA
AAGCGCCGCAACGCCGATGAACTCGAACGCCACCGCCATCATCTGGAGGAACTGGTCGCCGAGCGCACTGCTGAGCTGGC
CGTGGCGCATGAGGCAGCCGAAGCTGCCTCGCGGGCCAAGAGCGCATTCCTGGCCAACATGAGCCATGAAATCCGGACGC
CGATGAATGCCATCGTCGGCCTGACTTACATGTTGCGGCGAACGATTACCGACTCGGGCCAAGCGGACAAGCTGGGCAAG
ATTGCCGCCAGTGCCGATCACTTGCTTGGCGTGATCAACGACATCCTTGATATTTCCAAGATTGAAGCGAACAAGCTGGC
GTTGGACCAGTCGGAGTTCAATCTGGAGGAACTCCTGTCGCGCGTCACGTCAATGGTGATTGACCGGGTTCGCGAGAAAA
GGCTGGAGCTGATTATCGATACCGATGCCAGCCTGGGTTTCCTGATGGGCGATGCGACACGTCTTGGCCAGTCGCTGATC
AACTACCTCGGCAATGCAGTCAAGTTCACCGATTACGGCAGCATCGTCTTGCGTGCCCGCCTGGTCGAGGAAAGCAGCAA
CGATGTGTTGATCCGGTTTGAAGTCGAGGATACCGGGATCGGCGTTGCCCCGGAAAACCTGCCCCGCCTGTTCCAGGTGT
TCGAGCAGGGGGATAGCACAACAACGCGCCGCTACGGCGGTACCGGCCTTGGCCTGGCCATCACGCGCCGCTTGGCCCAG
TTGATGGGCGGTGAGGCCGGGGTCGAGAGCACTTTGGGGGTTGGCAGTACTTTCTGGCTGACGGCTCGACTGGGCCGGGT
CCGGGCAGCGACCGGACGCCATCGCATTCCCAGCCTGCGTGGCAAGCGGGCGCTGGTCATTGATGACATGCCGGTGACGC
GTCTGGTCCAGTCCCAGTTATTGCGGATGATCGGTCTGGAAGGTGAAGGTGCTGCGGGGGGGGCGGTGGCATTACAGGAA
ATCGAGGCGGCCGAGCGGGAAGGAAAACCCTACGATCTCGTTCTGGTTGATCTGCTGATGCCCGGCATGGACGGTTTCGA
AACCTTGGCCAGATTGCGCGCCCTGCCTTTGCGGCAGCAGCCGCTGGCCATCCTGGTGACCGCATCCAGCGATCCCGAGA
TCATTGAAGATGCCACCCGGATGGGTTTTGCCGAAGCGCTGCTCAAGCCCTTGTCGCCTAGTATGCTCAACGACTGCCTG
GTCCGGCATCTCGCCGATATCCCGGGGCAAACCGGTGGCATGCCGCTTGCCGATAAACCTGCCGGATCGGATGCCGAATC
AATTCTGAAAGCCGATTTCAGCAGTGCGCGGATTCTTCTGGTCGAGGATGAGCCGATCAACCAGGATGTCGCGCTGGCCA
TTCTTGAAGAAATTGGCTGGAAGATCGACGTGGCGGCGAACGGCAGGGAGTCGCTGGCTTTGGTTGAGGCGAACGATTAT
CAGGTCGTGTTGATGGACATGCAGATGCCGGTCATGGACGGTTTGGCCGCGACTCGCCAGATCCGCCGGCTCCCTGGCCA
CGAGACGCTACCGATCATTGCCATGACGGCCAATGCATTCAGCGAGGATCGTGACCGATGTGTTGAGGCGGGCATGAACG
ATTTTCTGTCCAAGCCGGTGGAGCCTGAGGTTCTTTACGCGATGTTGCTGAAATGGCTCAGGCACTGA

Upstream 100 bases:

>100_bases
GTTCAGCAGGTTTTTGGCTCGGGTTTGCCGGAAATTCGGGAGGGAGTAAATCCCACATGCTTTATCAGGTTATACTTAAG
TAATATATCGAATTAAAAAA

Downstream 100 bases:

>100_bases
GCCGGAGCGGAATATCGTGAGCCTGGGTTGCGGCTTTCCCTAATCGACAAGCCATCAGTCAGCCGCTATTCTCCGGCGCA
TTGGAGCCAGAGATGATTTT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1275; Mature: 1274

Protein sequence:

>1275_residues
MSFLSKMASPSSALSFRKQIIRPVLVSTIALAILILLSFAAYLDWRERERTALATQQVERIWQGMVDNNGRYLRWMATQV
ANDHRFVEAMQRGDRDALLALAGPRYRELHAQFDLSHWYFITPDRKVLLRVHDPERSGDEVRRKGLLDAEASGQMTTGLE
LGTTSVFTLRQVMPWRVNGNVIGYVEMGMEVESFAREIKRLTGLDVLTAVHKAYSSAEAFANGKKAFGLSGNWGDHAEIA
LLSQSFPGVPASLIASWQGFVRGSDPGVFDVIKGERIWSAKLIALLDNDQHPVASMAILRDIAADRVSRTQLLFFVGTGS
ALFIVLLMLALHRRVGSVEQHVIQANDALAASNQRFRDFSESSADWLWETDANLRFSYFSENLQRICGIDPQKVLGKARS
ELWLNDEINKPDALAGHLAVLENREAFRDFEYCLLNDRGEHLWLLASGIPYFDKEGHFAGYRGIGQNITVRKDLELAAEK
SAKLLREAVENVSVGFTIYDEEDRLVICNETYLDIYSDSSDLIVPGMHFADIIRKGAERGQYPEAQGDIDGWVCSRVAQH
QHPDGLAIEQELNDGRWLLIIENRTPSGYIVGNRIDITARKQAERQLLLLSMAVEQSTEGILITDVDANIEYVNEAFVRI
SGFSREEAIGQTPRILDSGLTPRETYAEMWAVLSRGQLWQGELINKRKSGEIYTERLTIMPMRQDGRVTHYVAVKEDVTE
KRRNADELERHRHHLEELVAERTAELAVAHEAAEAASRAKSAFLANMSHEIRTPMNAIVGLTYMLRRTITDSGQADKLGK
IAASADHLLGVINDILDISKIEANKLALDQSEFNLEELLSRVTSMVIDRVREKRLELIIDTDASLGFLMGDATRLGQSLI
NYLGNAVKFTDYGSIVLRARLVEESSNDVLIRFEVEDTGIGVAPENLPRLFQVFEQGDSTTTRRYGGTGLGLAITRRLAQ
LMGGEAGVESTLGVGSTFWLTARLGRVRAATGRHRIPSLRGKRALVIDDMPVTRLVQSQLLRMIGLEGEGAAGGAVALQE
IEAAEREGKPYDLVLVDLLMPGMDGFETLARLRALPLRQQPLAILVTASSDPEIIEDATRMGFAEALLKPLSPSMLNDCL
VRHLADIPGQTGGMPLADKPAGSDAESILKADFSSARILLVEDEPINQDVALAILEEIGWKIDVAANGRESLALVEANDY
QVVLMDMQMPVMDGLAATRQIRRLPGHETLPIIAMTANAFSEDRDRCVEAGMNDFLSKPVEPEVLYAMLLKWLRH

Sequences:

>Translated_1275_residues
MSFLSKMASPSSALSFRKQIIRPVLVSTIALAILILLSFAAYLDWRERERTALATQQVERIWQGMVDNNGRYLRWMATQV
ANDHRFVEAMQRGDRDALLALAGPRYRELHAQFDLSHWYFITPDRKVLLRVHDPERSGDEVRRKGLLDAEASGQMTTGLE
LGTTSVFTLRQVMPWRVNGNVIGYVEMGMEVESFAREIKRLTGLDVLTAVHKAYSSAEAFANGKKAFGLSGNWGDHAEIA
LLSQSFPGVPASLIASWQGFVRGSDPGVFDVIKGERIWSAKLIALLDNDQHPVASMAILRDIAADRVSRTQLLFFVGTGS
ALFIVLLMLALHRRVGSVEQHVIQANDALAASNQRFRDFSESSADWLWETDANLRFSYFSENLQRICGIDPQKVLGKARS
ELWLNDEINKPDALAGHLAVLENREAFRDFEYCLLNDRGEHLWLLASGIPYFDKEGHFAGYRGIGQNITVRKDLELAAEK
SAKLLREAVENVSVGFTIYDEEDRLVICNETYLDIYSDSSDLIVPGMHFADIIRKGAERGQYPEAQGDIDGWVCSRVAQH
QHPDGLAIEQELNDGRWLLIIENRTPSGYIVGNRIDITARKQAERQLLLLSMAVEQSTEGILITDVDANIEYVNEAFVRI
SGFSREEAIGQTPRILDSGLTPRETYAEMWAVLSRGQLWQGELINKRKSGEIYTERLTIMPMRQDGRVTHYVAVKEDVTE
KRRNADELERHRHHLEELVAERTAELAVAHEAAEAASRAKSAFLANMSHEIRTPMNAIVGLTYMLRRTITDSGQADKLGK
IAASADHLLGVINDILDISKIEANKLALDQSEFNLEELLSRVTSMVIDRVREKRLELIIDTDASLGFLMGDATRLGQSLI
NYLGNAVKFTDYGSIVLRARLVEESSNDVLIRFEVEDTGIGVAPENLPRLFQVFEQGDSTTTRRYGGTGLGLAITRRLAQ
LMGGEAGVESTLGVGSTFWLTARLGRVRAATGRHRIPSLRGKRALVIDDMPVTRLVQSQLLRMIGLEGEGAAGGAVALQE
IEAAEREGKPYDLVLVDLLMPGMDGFETLARLRALPLRQQPLAILVTASSDPEIIEDATRMGFAEALLKPLSPSMLNDCL
VRHLADIPGQTGGMPLADKPAGSDAESILKADFSSARILLVEDEPINQDVALAILEEIGWKIDVAANGRESLALVEANDY
QVVLMDMQMPVMDGLAATRQIRRLPGHETLPIIAMTANAFSEDRDRCVEAGMNDFLSKPVEPEVLYAMLLKWLRH
>Mature_1274_residues
SFLSKMASPSSALSFRKQIIRPVLVSTIALAILILLSFAAYLDWRERERTALATQQVERIWQGMVDNNGRYLRWMATQVA
NDHRFVEAMQRGDRDALLALAGPRYRELHAQFDLSHWYFITPDRKVLLRVHDPERSGDEVRRKGLLDAEASGQMTTGLEL
GTTSVFTLRQVMPWRVNGNVIGYVEMGMEVESFAREIKRLTGLDVLTAVHKAYSSAEAFANGKKAFGLSGNWGDHAEIAL
LSQSFPGVPASLIASWQGFVRGSDPGVFDVIKGERIWSAKLIALLDNDQHPVASMAILRDIAADRVSRTQLLFFVGTGSA
LFIVLLMLALHRRVGSVEQHVIQANDALAASNQRFRDFSESSADWLWETDANLRFSYFSENLQRICGIDPQKVLGKARSE
LWLNDEINKPDALAGHLAVLENREAFRDFEYCLLNDRGEHLWLLASGIPYFDKEGHFAGYRGIGQNITVRKDLELAAEKS
AKLLREAVENVSVGFTIYDEEDRLVICNETYLDIYSDSSDLIVPGMHFADIIRKGAERGQYPEAQGDIDGWVCSRVAQHQ
HPDGLAIEQELNDGRWLLIIENRTPSGYIVGNRIDITARKQAERQLLLLSMAVEQSTEGILITDVDANIEYVNEAFVRIS
GFSREEAIGQTPRILDSGLTPRETYAEMWAVLSRGQLWQGELINKRKSGEIYTERLTIMPMRQDGRVTHYVAVKEDVTEK
RRNADELERHRHHLEELVAERTAELAVAHEAAEAASRAKSAFLANMSHEIRTPMNAIVGLTYMLRRTITDSGQADKLGKI
AASADHLLGVINDILDISKIEANKLALDQSEFNLEELLSRVTSMVIDRVREKRLELIIDTDASLGFLMGDATRLGQSLIN
YLGNAVKFTDYGSIVLRARLVEESSNDVLIRFEVEDTGIGVAPENLPRLFQVFEQGDSTTTRRYGGTGLGLAITRRLAQL
MGGEAGVESTLGVGSTFWLTARLGRVRAATGRHRIPSLRGKRALVIDDMPVTRLVQSQLLRMIGLEGEGAAGGAVALQEI
EAAEREGKPYDLVLVDLLMPGMDGFETLARLRALPLRQQPLAILVTASSDPEIIEDATRMGFAEALLKPLSPSMLNDCLV
RHLADIPGQTGGMPLADKPAGSDAESILKADFSSARILLVEDEPINQDVALAILEEIGWKIDVAANGRESLALVEANDYQ
VVLMDMQMPVMDGLAATRQIRRLPGHETLPIIAMTANAFSEDRDRCVEAGMNDFLSKPVEPEVLYAMLLKWLRH

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=576, Percent_Identity=31.7708333333333, Blast_Score=260, Evalue=3e-70,
Organism=Escherichia coli, GI145693157, Length=528, Percent_Identity=32.5757575757576, Blast_Score=220, Evalue=4e-58,
Organism=Escherichia coli, GI87081816, Length=418, Percent_Identity=37.0813397129187, Blast_Score=196, Evalue=7e-51,
Organism=Escherichia coli, GI48994928, Length=406, Percent_Identity=32.512315270936, Blast_Score=174, Evalue=4e-44,
Organism=Escherichia coli, GI1788713, Length=427, Percent_Identity=29.2740046838407, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=30.6306306306306, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=29.0836653386454, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=28.7610619469027, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=384, Percent_Identity=23.4375, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=29.4372294372294, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1789453, Length=98, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1788393, Length=211, Percent_Identity=25.1184834123223, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=33.6134453781513, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786912, Length=293, Percent_Identity=25.938566552901, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=220, Percent_Identity=27.7272727272727, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=125, Percent_Identity=39.2, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322000, Length=152, Percent_Identity=32.2368421052632, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 141783; Mature: 141652

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLSKMASPSSALSFRKQIIRPVLVSTIALAILILLSFAAYLDWRERERTALATQQVER
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWQGMVDNNGRYLRWMATQVANDHRFVEAMQRGDRDALLALAGPRYRELHAQFDLSHWYF
HHHHHHCCCCCEEEEEHHHHCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHEECCCEEEE
ITPDRKVLLRVHDPERSGDEVRRKGLLDAEASGQMTTGLELGTTSVFTLRQVMPWRVNGN
ECCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHCCEEECCC
VIGYVEMGMEVESFAREIKRLTGLDVLTAVHKAYSSAEAFANGKKAFGLSGNWGDHAEIA
EEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEE
LLSQSFPGVPASLIASWQGFVRGSDPGVFDVIKGERIWSAKLIALLDNDQHPVASMAILR
EEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCEEHHEEEEEEECCCCCHHHHHHHHH
DIAADRVSRTQLLFFVGTGSALFIVLLMLALHRRVGSVEQHVIQANDALAASNQRFRDFS
HHHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHCCCHHHHCCC
ESSADWLWETDANLRFSYFSENLQRICGIDPQKVLGKARSELWLNDEINKPDALAGHLAV
CCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHH
LENREAFRDFEYCLLNDRGEHLWLLASGIPYFDKEGHFAGYRGIGQNITVRKDLELAAEK
HHCHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHH
SAKLLREAVENVSVGFTIYDEEDRLVICNETYLDIYSDSSDLIVPGMHFADIIRKGAERG
HHHHHHHHHHCCEEEEEEECCCCCEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHCC
QYPEAQGDIDGWVCSRVAQHQHPDGLAIEQELNDGRWLLIIENRTPSGYIVGNRIDITAR
CCCCCCCCCHHHHHHHHHHCCCCCCCEEHEECCCCEEEEEEECCCCCCEEECCEEEEEEH
KQAERQLLLLSMAVEQSTEGILITDVDANIEYVNEAFVRISGFSREEAIGQTPRILDSGL
HHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHEECCCCHHHHCCCCCHHHHCCC
TPRETYAEMWAVLSRGQLWQGELINKRKSGEIYTERLTIMPMRQDGRVTHYVAVKEDVTE
CCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCEEEEEEEHHHHHH
KRRNADELERHRHHLEELVAERTAELAVAHEAAEAASRAKSAFLANMSHEIRTPMNAIVG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LTYMLRRTITDSGQADKLGKIAASADHLLGVINDILDISKIEANKLALDQSEFNLEELLS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHH
RVTSMVIDRVREKRLELIIDTDASLGFLMGDATRLGQSLINYLGNAVKFTDYGSIVLRAR
HHHHHHHHHHHHHHEEEEEECCCCCHHHCCCHHHHHHHHHHHCCCCEEEECCCHHHHEEE
LVEESSNDVLIRFEVEDTGIGVAPENLPRLFQVFEQGDSTTTRRYGGTGLGLAITRRLAQ
HHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
LMGGEAGVESTLGVGSTFWLTARLGRVRAATGRHRIPSLRGKRALVIDDMPVTRLVQSQL
HHCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
LRMIGLEGEGAAGGAVALQEIEAAEREGKPYDLVLVDLLMPGMDGFETLARLRALPLRQQ
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHCCCCCC
PLAILVTASSDPEIIEDATRMGFAEALLKPLSPSMLNDCLVRHLADIPGQTGGMPLADKP
CEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AGSDAESILKADFSSARILLVEDEPINQDVALAILEEIGWKIDVAANGRESLALVEANDY
CCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCC
QVVLMDMQMPVMDGLAATRQIRRLPGHETLPIIAMTANAFSEDRDRCVEAGMNDFLSKPV
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHCCCC
EPEVLYAMLLKWLRH
CHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFLSKMASPSSALSFRKQIIRPVLVSTIALAILILLSFAAYLDWRERERTALATQQVER
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWQGMVDNNGRYLRWMATQVANDHRFVEAMQRGDRDALLALAGPRYRELHAQFDLSHWYF
HHHHHHCCCCCEEEEEHHHHCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHEECCCEEEE
ITPDRKVLLRVHDPERSGDEVRRKGLLDAEASGQMTTGLELGTTSVFTLRQVMPWRVNGN
ECCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHCCEEECCC
VIGYVEMGMEVESFAREIKRLTGLDVLTAVHKAYSSAEAFANGKKAFGLSGNWGDHAEIA
EEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEE
LLSQSFPGVPASLIASWQGFVRGSDPGVFDVIKGERIWSAKLIALLDNDQHPVASMAILR
EEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCEEHHEEEEEEECCCCCHHHHHHHHH
DIAADRVSRTQLLFFVGTGSALFIVLLMLALHRRVGSVEQHVIQANDALAASNQRFRDFS
HHHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHCCCHHHHCCC
ESSADWLWETDANLRFSYFSENLQRICGIDPQKVLGKARSELWLNDEINKPDALAGHLAV
CCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHH
LENREAFRDFEYCLLNDRGEHLWLLASGIPYFDKEGHFAGYRGIGQNITVRKDLELAAEK
HHCHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHH
SAKLLREAVENVSVGFTIYDEEDRLVICNETYLDIYSDSSDLIVPGMHFADIIRKGAERG
HHHHHHHHHHCCEEEEEEECCCCCEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHCC
QYPEAQGDIDGWVCSRVAQHQHPDGLAIEQELNDGRWLLIIENRTPSGYIVGNRIDITAR
CCCCCCCCCHHHHHHHHHHCCCCCCCEEHEECCCCEEEEEEECCCCCCEEECCEEEEEEH
KQAERQLLLLSMAVEQSTEGILITDVDANIEYVNEAFVRISGFSREEAIGQTPRILDSGL
HHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHEECCCCHHHHCCCCCHHHHCCC
TPRETYAEMWAVLSRGQLWQGELINKRKSGEIYTERLTIMPMRQDGRVTHYVAVKEDVTE
CCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCEEEEEEEHHHHHH
KRRNADELERHRHHLEELVAERTAELAVAHEAAEAASRAKSAFLANMSHEIRTPMNAIVG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LTYMLRRTITDSGQADKLGKIAASADHLLGVINDILDISKIEANKLALDQSEFNLEELLS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHH
RVTSMVIDRVREKRLELIIDTDASLGFLMGDATRLGQSLINYLGNAVKFTDYGSIVLRAR
HHHHHHHHHHHHHHEEEEEECCCCCHHHCCCHHHHHHHHHHHCCCCEEEECCCHHHHEEE
LVEESSNDVLIRFEVEDTGIGVAPENLPRLFQVFEQGDSTTTRRYGGTGLGLAITRRLAQ
HHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
LMGGEAGVESTLGVGSTFWLTARLGRVRAATGRHRIPSLRGKRALVIDDMPVTRLVQSQL
HHCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
LRMIGLEGEGAAGGAVALQEIEAAEREGKPYDLVLVDLLMPGMDGFETLARLRALPLRQQ
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHCCCCCC
PLAILVTASSDPEIIEDATRMGFAEALLKPLSPSMLNDCLVRHLADIPGQTGGMPLADKP
CEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AGSDAESILKADFSSARILLVEDEPINQDVALAILEEIGWKIDVAANGRESLALVEANDY
CCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCC
QVVLMDMQMPVMDGLAATRQIRRLPGHETLPIIAMTANAFSEDRDRCVEAGMNDFLSKPV
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHCCCC
EPEVLYAMLLKWLRH
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]