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The map label for this gene is ttuB [H]

Identifier: 71907745

GI number: 71907745

Start: 2289843

End: 2291174

Strand: Reverse

Name: ttuB [H]

Synonym: Daro_2119

Alternate gene names: 71907745

Gene position: 2291174-2289843 (Counterclockwise)

Preceding gene: 71907746

Following gene: 71907744

Centisome position: 50.9

GC content: 60.96

Gene sequence:

>1332_bases
ATGGCCAATGCACAAAGTGCCACGCTGCCCGCCAACATGTCGGCGAATCATGCCGAACTGGACGGCGCGTATCGCAAGGT
AACCCTGCACCTCATTCCCTTCATTTTTATTTGCTACCTGTTCAATTACCTGGACCGGGTCAATGTCGGCTTCGCGAAGT
TGCAGATGATCGACGCTCTGAAATGGAGCGAAACGATCTACGGTCTTGGCGCCGGAATCTTTTTTATCGGCTATGTCCTG
AGCGGCGTGCCGAGCAACCTCCTGCTGCACCGTCTCGGTGCCCGCAAGGTGATCGGCACCCTGATGATTGCCTGGGGCAT
CGCCTCGGCCTCGCTGATGTTCGTCAAGACCCCGGAAGCCTTCTACACGCTGCGCTTCATCACCGGCGTCTTCGAAGCCG
GCTTCTTCCCCGGCATCGTGCTCTACTTCACCAACTGGTTCCCGGCCTCGCGACGCGGCCGGATCATGGGCCTCTTCATG
TCGGCCATTCCCATCTCCGGGCTTCTGGGGAGCCCGCTCTCGGGCTGGATGATGCAGTCCTTTGCCGGTCAGGGCGGCCT
CGCCGGCTGGCAATGGATGTTCCTTCTGCAGGGCATTCCGACCGTGCTGCTCGGCCTCCTTGTTTATGTGATGCTCAATG
ACGGTATCGCCCAGGCGAAATGGCTGAGCACCGATGAAAAGCAGATGCTGATCGCCGAACTGGAAAAGGACGAAAAAAAT
CGCCGCGAAAGCAGTCTGGCGGCCGACACTTTTGCCAGCGTGCTGCGTAATCCGCATGTCTGGCTACTCGGCCTGGTCTA
CTTCTGCATCCAGATGGGGGTCTATGCCATCAACTTCTGGCTGCCGAGCATCATCAAATCGCTCGGCTTCCAGAGCCCGC
TGACCGTTGGCTGGATCAGCGCCATTCCTTATCTGTGCGCCAGCATCTTCATGATCTGGATCGGCCGCTCCGGCGACGCC
CGCAAGGAACGTCGCTGGCACTTGAGCGGTCCGCTGCTGATGGGCCTGTGCGGTCTGATGATTGCCACCATGGCCGGCGG
CAACGCTGTCATCGCCGTCTTCGGTCTCTCCCTGGCAACGATGGGGGCGCTGTCCGGCCTGCCGATGTTCTGGCCGCTGC
CGACCGCCTTCCTGGGCAGCGCCGCCGCAGCCGGTGGCCTCGCCCTGATCAACTCGCTCGGCCAGATCGCCGGTTTCATC
AGCCCCTTCCTGGTCGGCTGGATCAAGGATGCCACGGGCGGCACCACGGTCGCGCTCTACATCCTGTCCGGTGTGCTCTT
CTTCGGCGCCATGCTGGTCTTGCGTGTCCCGGCCAAAATCGTCAATCGCTAA

Upstream 100 bases:

>100_bases
TGATTTTACATGCATCCGCACGATGTTTGTCCATTGCCGGCACCCTACCATTTGCCTGCGTTATTGCAGTGGTAAATCAA
TTCACTATTAGGAGACAAAC

Downstream 100 bases:

>100_bases
CCCGGTGAATTGCGGCTTGGGCGACCTGCCTCGCCCAAGCCGCATGACGAAGTCACACCCACTCCGAGGATTTCAGACAT
GACCACTCCCATCCAGCCGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MANAQSATLPANMSANHAELDGAYRKVTLHLIPFIFICYLFNYLDRVNVGFAKLQMIDALKWSETIYGLGAGIFFIGYVL
SGVPSNLLLHRLGARKVIGTLMIAWGIASASLMFVKTPEAFYTLRFITGVFEAGFFPGIVLYFTNWFPASRRGRIMGLFM
SAIPISGLLGSPLSGWMMQSFAGQGGLAGWQWMFLLQGIPTVLLGLLVYVMLNDGIAQAKWLSTDEKQMLIAELEKDEKN
RRESSLAADTFASVLRNPHVWLLGLVYFCIQMGVYAINFWLPSIIKSLGFQSPLTVGWISAIPYLCASIFMIWIGRSGDA
RKERRWHLSGPLLMGLCGLMIATMAGGNAVIAVFGLSLATMGALSGLPMFWPLPTAFLGSAAAAGGLALINSLGQIAGFI
SPFLVGWIKDATGGTTVALYILSGVLFFGAMLVLRVPAKIVNR

Sequences:

>Translated_443_residues
MANAQSATLPANMSANHAELDGAYRKVTLHLIPFIFICYLFNYLDRVNVGFAKLQMIDALKWSETIYGLGAGIFFIGYVL
SGVPSNLLLHRLGARKVIGTLMIAWGIASASLMFVKTPEAFYTLRFITGVFEAGFFPGIVLYFTNWFPASRRGRIMGLFM
SAIPISGLLGSPLSGWMMQSFAGQGGLAGWQWMFLLQGIPTVLLGLLVYVMLNDGIAQAKWLSTDEKQMLIAELEKDEKN
RRESSLAADTFASVLRNPHVWLLGLVYFCIQMGVYAINFWLPSIIKSLGFQSPLTVGWISAIPYLCASIFMIWIGRSGDA
RKERRWHLSGPLLMGLCGLMIATMAGGNAVIAVFGLSLATMGALSGLPMFWPLPTAFLGSAAAAGGLALINSLGQIAGFI
SPFLVGWIKDATGGTTVALYILSGVLFFGAMLVLRVPAKIVNR
>Mature_442_residues
ANAQSATLPANMSANHAELDGAYRKVTLHLIPFIFICYLFNYLDRVNVGFAKLQMIDALKWSETIYGLGAGIFFIGYVLS
GVPSNLLLHRLGARKVIGTLMIAWGIASASLMFVKTPEAFYTLRFITGVFEAGFFPGIVLYFTNWFPASRRGRIMGLFMS
AIPISGLLGSPLSGWMMQSFAGQGGLAGWQWMFLLQGIPTVLLGLLVYVMLNDGIAQAKWLSTDEKQMLIAELEKDEKNR
RESSLAADTFASVLRNPHVWLLGLVYFCIQMGVYAINFWLPSIIKSLGFQSPLTVGWISAIPYLCASIFMIWIGRSGDAR
KERRWHLSGPLLMGLCGLMIATMAGGNAVIAVFGLSLATMGALSGLPMFWPLPTAFLGSAAAAGGLALINSLGQIAGFIS
PFLVGWIKDATGGTTVALYILSGVLFFGAMLVLRVPAKIVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=402, Percent_Identity=21.6417910447761, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87082071, Length=436, Percent_Identity=36.9266055045872, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI2367379, Length=428, Percent_Identity=25.2336448598131, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789152, Length=415, Percent_Identity=23.1325301204819, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082320, Length=438, Percent_Identity=23.0593607305936, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789515, Length=422, Percent_Identity=26.0663507109005, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082310, Length=281, Percent_Identity=24.9110320284698, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319876, Length=328, Percent_Identity=26.219512195122, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322025, Length=293, Percent_Identity=25.5972696245734, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323032, Length=301, Percent_Identity=24.2524916943522, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321698, Length=359, Percent_Identity=22.5626740947075, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=147, Percent_Identity=25.1700680272109, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24584153, Length=366, Percent_Identity=24.0437158469945, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24583789, Length=368, Percent_Identity=24.7282608695652, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20130167, Length=416, Percent_Identity=21.1538461538462, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48098; Mature: 47967

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANAQSATLPANMSANHAELDGAYRKVTLHLIPFIFICYLFNYLDRVNVGFAKLQMIDAL
CCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KWSETIYGLGAGIFFIGYVLSGVPSNLLLHRLGARKVIGTLMIAWGIASASLMFVKTPEA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHH
FYTLRFITGVFEAGFFPGIVLYFTNWFPASRRGRIMGLFMSAIPISGLLGSPLSGWMMQS
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
FAGQGGLAGWQWMFLLQGIPTVLLGLLVYVMLNDGIAQAKWLSTDEKQMLIAELEKDEKN
HCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHH
RRESSLAADTFASVLRNPHVWLLGLVYFCIQMGVYAINFWLPSIIKSLGFQSPLTVGWIS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AIPYLCASIFMIWIGRSGDARKERRWHLSGPLLMGLCGLMIATMAGGNAVIAVFGLSLAT
HHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
MGALSGLPMFWPLPTAFLGSAAAAGGLALINSLGQIAGFISPFLVGWIKDATGGTTVALY
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ILSGVLFFGAMLVLRVPAKIVNR
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]