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The map label for this gene is icfG [H]

Identifier: 71907622

GI number: 71907622

Start: 2143768

End: 2145894

Strand: Reverse

Name: icfG [H]

Synonym: Daro_1993

Alternate gene names: 71907622

Gene position: 2145894-2143768 (Counterclockwise)

Preceding gene: 71907623

Following gene: 71907619

Centisome position: 47.67

GC content: 59.47

Gene sequence:

>2127_bases
GTGACGCGACCAAGCGGACTGCTCCTTGCAGCGATCCGGGCCGGACGCGGCCGGGCGCTCCCGCTGCTGTTGCTGCTCCT
CGCAGCCTTGGTGCTGAATGGAATCGAGAACACACCACTGCTCAGTGTTCGCGAGGCGCAATTCGACCACTACCAGCGAC
TGATGCCGCGTGCTCGCGACAGCGAGCCAGTCATCATCGTCGGAATTGATAGCCAGAGCCTGGTCAAGCACGGGCAATGG
CCGTGGTCGCGAGATCTGGTCGCCCGATTGGCGGACAAGATACTCGCTGGCAAACCTCTGGCCCTGGGCATCGATATTGT
TTTTGCCGAGCGTGATCGCTACAGCCCGGAAATCCTTGCCAATCAGTTCCCCGGCTTGCCGGCCGATGCATTTGCAAAAC
TACCCGAGCCCGACCAGCAACTGGCCCTGGCCCTGGCTGGACAGCCGACCGTATTGGCTGTTGTCGGCTTGAGCAAGTTG
CTGCCCGGTTCAAAACAACCGACCAGGCCGCTCCCGGTTTTCAGCCAGGAGCCCAGTCACGACCAATACCTGCCGCATTA
CGCCAGCGCCTTTGCCAGCCGCCCTCTTCTTGAAAGTGCCGCAGCTGGCGAGGGTTTGATCAACGCCAGCCCAGGCTTGC
TGCAGTCGAACAGTGAGCGCGGCATACTGCGCCGAGTGCCAACCCTGTCATTGATCAACGACCTGCCCTTCCTGTCATTG
CCACTGGAAATGGTTCGCCTGGCGCTTGGCCCTGGTGGCAAGGTGGCAATGGAAGGTGGAAGTCATGGCCTGACCGCAGT
CCGGATTGGTAGCTACCGCCTGCCGACCCGCCCGAATGGCGAACTACTGATGCATTTCGGCCGCGCCAACTCCAATTACT
ATCTTTCTGCCGCTGACGTGCTGGCGGGCGTACATCCTCCGGAGCTCTTCAACAACCACTTCGTCATCATCGGCTTTAAC
AGCACAGGTCTGCAGGACCGCATCATCACCCCACTCGGCGAAAGCCTGCCGGGGATCGATATTCACGCTCAGGTCATCGA
AAGCCTGTTGGATGGACAGGCATTACAACGCCCCTACTGGATAGCGCAGATCGAACTGGCTTCACTGTTGTGTGGCGGTT
TGCTGCTGATCGGCACTATCCCGTTGCTCAGGGCGCGACGCTACGCGGCCCTGAGTTTTACCGTTCTAATGCTGTTTCTC
CTGGCCGGCGGCTACCTCGCTTTTTTTGCCGGACGTTGGCTTTTCGACGGTGCTTCGCAAATTATCCTGCTCAGCCCGGT
TTTCATAGCGTTGCTTGGCAACACACTGATCACCGCTGACACCCAGCGTCGCGAGGCGGAACGGCAGTTGCAGAAAAGCC
GTGAAGAGGCGGCATGGGTTAATGGTGAACTCGATGCGGCAAGGCGAATCCAGATGGGGTTGTTACCGGACACCACCGCG
ATGTTTGCCGAGGAAACCCGATTTGAGGTGGCCGCCTTGCTCGAACCGGCTCGAGCGGTAGGTGGTGACTACTACGATTG
CTTCATGCTCGACGACCGTCGGCTCTGCCTGGCCATCGGCGACGTCTCCGGCAAGGGCGTGCCAGCCAGCCTGTTCATGG
CAATCTCGAAGACCCTGACCGGTACGCTGGCCCGCCGCCAACATGACCTCGGACTGGCGCTCCGAGAAATCGAAAGCGAA
CTGAACCGGGAGAATCCGGAATGCCTGTTCGTCACCGCCTTCATCAGCATCCTGGATATCGAAACCGGCACCATGGAATA
TGCCTGCGCCGGCCACGATGCTCCCATCGTGCTGCGAGACGGTGGTCTGTCGCGCATCGATACGGCAAACATTTCCGGAC
CACCACTATGCACTGCCGATGACTACCCGTTCCTTGCTGCAAAAGTGCAACTGCTACCAGGCGATCTGCTTTGTCTGTTT
ACTGACGGCGTCACCGAAGCCATGAACGACAAGGAAATGTTCGGCAGCGACCGACTGTTGGCGAACATCGGCGAGCTCCA
GGCCGCTGATCTTCCGGCAGCCATCAAGACACTGCGCGATGCTGTTCGGTATTTCGAAGCAGGTCACCCATCATCGGATG
ACCTGACCCTGCTCTTGATGCGCTGGAACGGGCCTAGCGTACGTTGA

Upstream 100 bases:

>100_bases
CGCGACTGGTTGCTGAAACGCGACGCCTCGAGCAGATCACCCGAGGCAGCCGGGCACCACTCGAAATCATTTCTGCCTAC
GACGGGTTAGCCATAGACCT

Downstream 100 bases:

>100_bases
TTTCAACGCGTCGATTCTTCGGTTCGTCGACTTCGTCTGCCGTCGGCACCAGCGGGTCGCGCTCACCGCGCCCAACCGCT
TCCATCTTTTCGGCCGAGAT

Product: stage II sporulation E family protein

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 708; Mature: 707

Protein sequence:

>708_residues
MTRPSGLLLAAIRAGRGRALPLLLLLLAALVLNGIENTPLLSVREAQFDHYQRLMPRARDSEPVIIVGIDSQSLVKHGQW
PWSRDLVARLADKILAGKPLALGIDIVFAERDRYSPEILANQFPGLPADAFAKLPEPDQQLALALAGQPTVLAVVGLSKL
LPGSKQPTRPLPVFSQEPSHDQYLPHYASAFASRPLLESAAAGEGLINASPGLLQSNSERGILRRVPTLSLINDLPFLSL
PLEMVRLALGPGGKVAMEGGSHGLTAVRIGSYRLPTRPNGELLMHFGRANSNYYLSAADVLAGVHPPELFNNHFVIIGFN
STGLQDRIITPLGESLPGIDIHAQVIESLLDGQALQRPYWIAQIELASLLCGGLLLIGTIPLLRARRYAALSFTVLMLFL
LAGGYLAFFAGRWLFDGASQIILLSPVFIALLGNTLITADTQRREAERQLQKSREEAAWVNGELDAARRIQMGLLPDTTA
MFAEETRFEVAALLEPARAVGGDYYDCFMLDDRRLCLAIGDVSGKGVPASLFMAISKTLTGTLARRQHDLGLALREIESE
LNRENPECLFVTAFISILDIETGTMEYACAGHDAPIVLRDGGLSRIDTANISGPPLCTADDYPFLAAKVQLLPGDLLCLF
TDGVTEAMNDKEMFGSDRLLANIGELQAADLPAAIKTLRDAVRYFEAGHPSSDDLTLLLMRWNGPSVR

Sequences:

>Translated_708_residues
MTRPSGLLLAAIRAGRGRALPLLLLLLAALVLNGIENTPLLSVREAQFDHYQRLMPRARDSEPVIIVGIDSQSLVKHGQW
PWSRDLVARLADKILAGKPLALGIDIVFAERDRYSPEILANQFPGLPADAFAKLPEPDQQLALALAGQPTVLAVVGLSKL
LPGSKQPTRPLPVFSQEPSHDQYLPHYASAFASRPLLESAAAGEGLINASPGLLQSNSERGILRRVPTLSLINDLPFLSL
PLEMVRLALGPGGKVAMEGGSHGLTAVRIGSYRLPTRPNGELLMHFGRANSNYYLSAADVLAGVHPPELFNNHFVIIGFN
STGLQDRIITPLGESLPGIDIHAQVIESLLDGQALQRPYWIAQIELASLLCGGLLLIGTIPLLRARRYAALSFTVLMLFL
LAGGYLAFFAGRWLFDGASQIILLSPVFIALLGNTLITADTQRREAERQLQKSREEAAWVNGELDAARRIQMGLLPDTTA
MFAEETRFEVAALLEPARAVGGDYYDCFMLDDRRLCLAIGDVSGKGVPASLFMAISKTLTGTLARRQHDLGLALREIESE
LNRENPECLFVTAFISILDIETGTMEYACAGHDAPIVLRDGGLSRIDTANISGPPLCTADDYPFLAAKVQLLPGDLLCLF
TDGVTEAMNDKEMFGSDRLLANIGELQAADLPAAIKTLRDAVRYFEAGHPSSDDLTLLLMRWNGPSVR
>Mature_707_residues
TRPSGLLLAAIRAGRGRALPLLLLLLAALVLNGIENTPLLSVREAQFDHYQRLMPRARDSEPVIIVGIDSQSLVKHGQWP
WSRDLVARLADKILAGKPLALGIDIVFAERDRYSPEILANQFPGLPADAFAKLPEPDQQLALALAGQPTVLAVVGLSKLL
PGSKQPTRPLPVFSQEPSHDQYLPHYASAFASRPLLESAAAGEGLINASPGLLQSNSERGILRRVPTLSLINDLPFLSLP
LEMVRLALGPGGKVAMEGGSHGLTAVRIGSYRLPTRPNGELLMHFGRANSNYYLSAADVLAGVHPPELFNNHFVIIGFNS
TGLQDRIITPLGESLPGIDIHAQVIESLLDGQALQRPYWIAQIELASLLCGGLLLIGTIPLLRARRYAALSFTVLMLFLL
AGGYLAFFAGRWLFDGASQIILLSPVFIALLGNTLITADTQRREAERQLQKSREEAAWVNGELDAARRIQMGLLPDTTAM
FAEETRFEVAALLEPARAVGGDYYDCFMLDDRRLCLAIGDVSGKGVPASLFMAISKTLTGTLARRQHDLGLALREIESEL
NRENPECLFVTAFISILDIETGTMEYACAGHDAPIVLRDGGLSRIDTANISGPPLCTADDYPFLAAKVQLLPGDLLCLFT
DGVTEAMNDKEMFGSDRLLANIGELQAADLPAAIKTLRDAVRYFEAGHPSSDDLTLLLMRWNGPSVR

Specific function: Involved in cross-regulation of inorganic carbon and glucose metabolisms [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003660
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00672 HAMP; PF07228 SpoIIE [H]

EC number: 4.6.1.1

Molecular weight: Translated: 76767; Mature: 76636

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPSGLLLAAIRAGRGRALPLLLLLLAALVLNGIENTPLLSVREAQFDHYQRLMPRARD
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCCCC
SEPVIIVGIDSQSLVKHGQWPWSRDLVARLADKILAGKPLALGIDIVFAERDRYSPEILA
CCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHH
NQFPGLPADAFAKLPEPDQQLALALAGQPTVLAVVGLSKLLPGSKQPTRPLPVFSQEPSH
HCCCCCCHHHHHCCCCCHHHHEEEECCCCCEEEEECHHHHCCCCCCCCCCCCCCCCCCCC
DQYLPHYASAFASRPLLESAAAGEGLINASPGLLQSNSERGILRRVPTLSLINDLPFLSL
CCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHCCCCHHH
PLEMVRLALGPGGKVAMEGGSHGLTAVRIGSYRLPTRPNGELLMHFGRANSNYYLSAADV
HHHHHHHHCCCCCEEEECCCCCCEEEEEECCEECCCCCCCCEEEEEECCCCCEEEEHHHH
LAGVHPPELFNNHFVIIGFNSTGLQDRIITPLGESLPGIDIHAQVIESLLDGQALQRPYW
HCCCCCHHHHCCCEEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCEE
IAQIELASLLCGGLLLIGTIPLLRARRYAALSFTVLMLFLLAGGYLAFFAGRWLFDGASQ
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC
IILLSPVFIALLGNTLITADTQRREAERQLQKSREEAAWVNGELDAARRIQMGLLPDTTA
EEEHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHH
MFAEETRFEVAALLEPARAVGGDYYDCFMLDDRRLCLAIGDVSGKGVPASLFMAISKTLT
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHH
GTLARRQHDLGLALREIESELNRENPECLFVTAFISILDIETGTMEYACAGHDAPIVLRD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHEEHHHHHCCCCCCEEEEECCCCCCEEEEC
GGLSRIDTANISGPPLCTADDYPFLAAKVQLLPGDLLCLFTDGVTEAMNDKEMFGSDRLL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCHHHHCCCHHHHCCCHHH
ANIGELQAADLPAAIKTLRDAVRYFEAGHPSSDDLTLLLMRWNGPSVR
HHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
TRPSGLLLAAIRAGRGRALPLLLLLLAALVLNGIENTPLLSVREAQFDHYQRLMPRARD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCCCC
SEPVIIVGIDSQSLVKHGQWPWSRDLVARLADKILAGKPLALGIDIVFAERDRYSPEILA
CCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHH
NQFPGLPADAFAKLPEPDQQLALALAGQPTVLAVVGLSKLLPGSKQPTRPLPVFSQEPSH
HCCCCCCHHHHHCCCCCHHHHEEEECCCCCEEEEECHHHHCCCCCCCCCCCCCCCCCCCC
DQYLPHYASAFASRPLLESAAAGEGLINASPGLLQSNSERGILRRVPTLSLINDLPFLSL
CCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHCCCCHHH
PLEMVRLALGPGGKVAMEGGSHGLTAVRIGSYRLPTRPNGELLMHFGRANSNYYLSAADV
HHHHHHHHCCCCCEEEECCCCCCEEEEEECCEECCCCCCCCEEEEEECCCCCEEEEHHHH
LAGVHPPELFNNHFVIIGFNSTGLQDRIITPLGESLPGIDIHAQVIESLLDGQALQRPYW
HCCCCCHHHHCCCEEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCEE
IAQIELASLLCGGLLLIGTIPLLRARRYAALSFTVLMLFLLAGGYLAFFAGRWLFDGASQ
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC
IILLSPVFIALLGNTLITADTQRREAERQLQKSREEAAWVNGELDAARRIQMGLLPDTTA
EEEHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHH
MFAEETRFEVAALLEPARAVGGDYYDCFMLDDRRLCLAIGDVSGKGVPASLFMAISKTLT
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHH
GTLARRQHDLGLALREIESELNRENPECLFVTAFISILDIETGTMEYACAGHDAPIVLRD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHEEHHHHHCCCCCCEEEEECCCCCCEEEEC
GGLSRIDTANISGPPLCTADDYPFLAAKVQLLPGDLLCLFTDGVTEAMNDKEMFGSDRLL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCHHHHCCCHHHHCCCHHH
ANIGELQAADLPAAIKTLRDAVRYFEAGHPSSDDLTLLLMRWNGPSVR
HHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8075401; 8905231 [H]