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The map label for this gene is czcB [H]

Identifier: 71907505

GI number: 71907505

Start: 2017927

End: 2019054

Strand: Reverse

Name: czcB [H]

Synonym: Daro_1876

Alternate gene names: 71907505

Gene position: 2019054-2017927 (Counterclockwise)

Preceding gene: 71907506

Following gene: 71907504

Centisome position: 44.86

GC content: 64.89

Gene sequence:

>1128_bases
ATGAAGCTGACCTCCCCTCTCCTTATCCTGTTGCTGGCCCTGGCCGGCTGCTCGGCCGAACCGGAAGCGCAGAAAGCCGC
CGCGATCAAGGTGGATGGCGACCGCGCCCTGCTCGCCGAACCGGACAAGGCGACTTTTCTGAAACTGGCCGTCGTCGAAA
AGGACAAGGGCGGCCTGCTGCGCCTGCCCGGCCGGCTGATCTGGAACGAAGAAAAAACGGTCCGCGTCTTCCCGCAACTG
GGGGGCCGCGTGCAGGGCATCGCCGTCGATGTCGGCGCGACAGTCAAGATCGGCCAGCCGCTGGCCACCCTGAGTTCGCC
GGAATATGGCCAGGCGCTGGCTGATGCCCGCAAGGCCCGGGCCGATGCCCAGGTCGCCACTCAGGGCCTGGAGCGCAATC
GCGTTCTGCGCGAAGCCGGTGTTGTCGCCGAAAAGGATTGGCAGCAGGCTGAAGCCACGGCCATCGCCGCCAAGGCCGAA
GCCGAACGGGCGACCCGTCGCCTGGCTGGCCTCGGTGGTGAAGGCGATGGCACCTATGTGCTGCGTACGCCGCTGGCGGG
CGTGGTCGTCGAACGCAACCTGAATCCGGGCATGGAGTTCCGCCCCGATCAGTCCGGAGCGCCGCTGTTCGTCGTCACCG
ATCCGTCCAGCCTGTGGGTTCAGGTTGATGCTGGCGAAGCCGACCTGGCCAAGCTGAAAAAGGGCGAGCCGCTGCTGATT
GAATCGAAGCAATATCCTGGCGAGCGCTTCAAGGGCGTCATTCGCCACGTCGCCGATTTCGTCGACCCGAATACGCGGAC
GATCAAGGTCCGTGGCGAAGTGCCGAATGCCGACCGGCGCCTGAAGGGCGAGATGTTCGTCAATGCCCTGGTCGAACTGG
CCCCGACGCCTGCCCTGCGCGCACCGGCCACCGCCGTCTTCCTGTTCGGCAACAAACGCTATGTGTTCGTGGAGGAAGTG
CCCGGGCGCTATCGTCGACAGCTGGTTGAAGCCGGCGCCGAGCGCGATGGCCTGATCGACCTGATGTCAGGCGTCAATGA
GGGCGACAAAGTCGTCACCGAAGGCAGCCTGCACCTGCTGAAATACTTCAAGCCGGCCGCAGCCGCTGAAAAACAGGCAG
CCAAATGA

Upstream 100 bases:

>100_bases
GCACGCTGCGCCAGATTCAGATTGAAGCAGCCAGCGCCCGTGCTGACTACGCCAAAGCATTGTCGGACTGGCAGACCCAG
GCCGAATTCAGGAAATCCCC

Downstream 100 bases:

>100_bases
TCAAGCGCATTGTTCATTTCGCGCTCAATCAGCCGCTGTTCATCATTCTCGGACTGGTGCTGTTCATCGGCATCGGTGTT
GCCTCTTTTCGCTCGCTGCC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MKLTSPLLILLLALAGCSAEPEAQKAAAIKVDGDRALLAEPDKATFLKLAVVEKDKGGLLRLPGRLIWNEEKTVRVFPQL
GGRVQGIAVDVGATVKIGQPLATLSSPEYGQALADARKARADAQVATQGLERNRVLREAGVVAEKDWQQAEATAIAAKAE
AERATRRLAGLGGEGDGTYVLRTPLAGVVVERNLNPGMEFRPDQSGAPLFVVTDPSSLWVQVDAGEADLAKLKKGEPLLI
ESKQYPGERFKGVIRHVADFVDPNTRTIKVRGEVPNADRRLKGEMFVNALVELAPTPALRAPATAVFLFGNKRYVFVEEV
PGRYRRQLVEAGAERDGLIDLMSGVNEGDKVVTEGSLHLLKYFKPAAAAEKQAAK

Sequences:

>Translated_375_residues
MKLTSPLLILLLALAGCSAEPEAQKAAAIKVDGDRALLAEPDKATFLKLAVVEKDKGGLLRLPGRLIWNEEKTVRVFPQL
GGRVQGIAVDVGATVKIGQPLATLSSPEYGQALADARKARADAQVATQGLERNRVLREAGVVAEKDWQQAEATAIAAKAE
AERATRRLAGLGGEGDGTYVLRTPLAGVVVERNLNPGMEFRPDQSGAPLFVVTDPSSLWVQVDAGEADLAKLKKGEPLLI
ESKQYPGERFKGVIRHVADFVDPNTRTIKVRGEVPNADRRLKGEMFVNALVELAPTPALRAPATAVFLFGNKRYVFVEEV
PGRYRRQLVEAGAERDGLIDLMSGVNEGDKVVTEGSLHLLKYFKPAAAAEKQAAK
>Mature_375_residues
MKLTSPLLILLLALAGCSAEPEAQKAAAIKVDGDRALLAEPDKATFLKLAVVEKDKGGLLRLPGRLIWNEEKTVRVFPQL
GGRVQGIAVDVGATVKIGQPLATLSSPEYGQALADARKARADAQVATQGLERNRVLREAGVVAEKDWQQAEATAIAAKAE
AERATRRLAGLGGEGDGTYVLRTPLAGVVVERNLNPGMEFRPDQSGAPLFVVTDPSSLWVQVDAGEADLAKLKKGEPLLI
ESKQYPGERFKGVIRHVADFVDPNTRTIKVRGEVPNADRRLKGEMFVNALVELAPTPALRAPATAVFLFGNKRYVFVEEV
PGRYRRQLVEAGAERDGLIDLMSGVNEGDKVVTEGSLHLLKYFKPAAAAEKQAAK

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=310, Percent_Identity=28.3870967741935, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082036, Length=298, Percent_Identity=26.1744966442953, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40337; Mature: 40337

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTSPLLILLLALAGCSAEPEAQKAAAIKVDGDRALLAEPDKATFLKLAVVEKDKGGLL
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEECCCCCEEEEEEEEECCCCCEE
RLPGRLIWNEEKTVRVFPQLGGRVQGIAVDVGATVKIGQPLATLSSPEYGQALADARKAR
ECCCEEEECCCCEEEEEHHHCCEEEEEEEECCCEEECCCCHHHCCCCCHHHHHHHHHHHH
ADAQVATQGLERNRVLREAGVVAEKDWQQAEATAIAAKAEAERATRRLAGLGGEGDGTYV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LRTPLAGVVVERNLNPGMEFRPDQSGAPLFVVTDPSSLWVQVDAGEADLAKLKKGEPLLI
EECCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCHHHHHHCCCCCEEE
ESKQYPGERFKGVIRHVADFVDPNTRTIKVRGEVPNADRRLKGEMFVNALVELAPTPALR
ECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCC
APATAVFLFGNKRYVFVEEVPGRYRRQLVEAGAERDGLIDLMSGVNEGDKVVTEGSLHLL
CCCEEEEEECCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCHHHH
KYFKPAAAAEKQAAK
HHHCCHHHHHHHCCC
>Mature Secondary Structure
MKLTSPLLILLLALAGCSAEPEAQKAAAIKVDGDRALLAEPDKATFLKLAVVEKDKGGLL
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEECCCCCEEEEEEEEECCCCCEE
RLPGRLIWNEEKTVRVFPQLGGRVQGIAVDVGATVKIGQPLATLSSPEYGQALADARKAR
ECCCEEEECCCCEEEEEHHHCCEEEEEEEECCCEEECCCCHHHCCCCCHHHHHHHHHHHH
ADAQVATQGLERNRVLREAGVVAEKDWQQAEATAIAAKAEAERATRRLAGLGGEGDGTYV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LRTPLAGVVVERNLNPGMEFRPDQSGAPLFVVTDPSSLWVQVDAGEADLAKLKKGEPLLI
EECCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCHHHHHHCCCCCEEE
ESKQYPGERFKGVIRHVADFVDPNTRTIKVRGEVPNADRRLKGEMFVNALVELAPTPALR
ECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCC
APATAVFLFGNKRYVFVEEVPGRYRRQLVEAGAERDGLIDLMSGVNEGDKVVTEGSLHLL
CCCEEEEEECCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCHHHH
KYFKPAAAAEKQAAK
HHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]