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The map label for this gene is rio1 [H]

Identifier: 71907495

GI number: 71907495

Start: 2004792

End: 2005628

Strand: Reverse

Name: rio1 [H]

Synonym: Daro_1866

Alternate gene names: 71907495

Gene position: 2005628-2004792 (Counterclockwise)

Preceding gene: 71907496

Following gene: 71907494

Centisome position: 44.56

GC content: 58.42

Gene sequence:

>837_bases
ATGAAAACCCCGAAAAGACTCACCACCCTCGTTGAAGAAGGCCTTGTAGACGAGGTGATCGGGCAGTTGATGAGCGGCAA
GGAAGCCACCGTCTATATCGTGCGTTGCGGCGAGCACATTCGTTGCGCAAAGGTTTACAAAGACGCCAAGCAGCGAAGCT
TCCGCAAGGCCACGTCCTATCAGGAAGGCCGCAAGGTCAAGAACAGCCGGCAGGCGCGGGCCATGGAGAAAGGCAGCCGC
TACGGGCGCCAGATGCAGGAGGAAGTCTGGCAGAACGCTGAGGTCGATGCGCTGTATCGGCTGGCTGCTGCCGGCGTGCG
GGTGCCGCAGCCTTACATCTGTTTTGATGGCGTTTTGCTGATGGATCTGGTGGTCGATGCCGATGGTGGCGCCGCGCCGC
GGCTGAACGATGTCGCCCTGAGCGAAGCAGTGGCGCTGGAGTTTCACGCCATGCTGGTCAATCAGGTGGTGCGCATGCTG
TGCGCCGGGATCATTCACGGCGATCTCTCGGAATACAACATCCTCGTCGATGAAAACGGGCCGGTCATCATCGACCTGCC
ACAAGCCATCGATGCGGCTGCCAACAGCACCGCAGCCGAAATGCTGGAGCGCGACGTCAACAATCTGCGCAGCTATTTCA
GCACCTTTGCCCCCTCACTCGCTGACAGCCAGTACGGCAAGGAAATCTGGGCGCTATACGAGAGCGGTTTGCTCCAGCCA
GAGCAGGTTTTGACCGGTAAGGTTGAACTCGACGAAAGCCTTGCCGACGTCGATGCCGTACTGCTGCAAATTGAAGAAGC
GATCAAGGAAGACGAAATTCGTCGGATGTGCCAGTAA

Upstream 100 bases:

>100_bases
TGAGCGATTTTCCGCCTGACCGGGCATTTTCTGGCCTTACCGTGGTCTGATTCGCATCTGAATCACGCCGAACCCCAAGC
TGTTCAAGCAAGCGAAGCCG

Downstream 100 bases:

>100_bases
ACTCAAGGCGGATGCCTGAGCGAGTTGTTACAAGCAGTCACTTCCAGACCGTCGTAAACCCGCGAGAATCAGGCCTGAAA
ATTTCTGCAGAATGTTTTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKTPKRLTTLVEEGLVDEVIGQLMSGKEATVYIVRCGEHIRCAKVYKDAKQRSFRKATSYQEGRKVKNSRQARAMEKGSR
YGRQMQEEVWQNAEVDALYRLAAAGVRVPQPYICFDGVLLMDLVVDADGGAAPRLNDVALSEAVALEFHAMLVNQVVRML
CAGIIHGDLSEYNILVDENGPVIIDLPQAIDAAANSTAAEMLERDVNNLRSYFSTFAPSLADSQYGKEIWALYESGLLQP
EQVLTGKVELDESLADVDAVLLQIEEAIKEDEIRRMCQ

Sequences:

>Translated_278_residues
MKTPKRLTTLVEEGLVDEVIGQLMSGKEATVYIVRCGEHIRCAKVYKDAKQRSFRKATSYQEGRKVKNSRQARAMEKGSR
YGRQMQEEVWQNAEVDALYRLAAAGVRVPQPYICFDGVLLMDLVVDADGGAAPRLNDVALSEAVALEFHAMLVNQVVRML
CAGIIHGDLSEYNILVDENGPVIIDLPQAIDAAANSTAAEMLERDVNNLRSYFSTFAPSLADSQYGKEIWALYESGLLQP
EQVLTGKVELDESLADVDAVLLQIEEAIKEDEIRRMCQ
>Mature_278_residues
MKTPKRLTTLVEEGLVDEVIGQLMSGKEATVYIVRCGEHIRCAKVYKDAKQRSFRKATSYQEGRKVKNSRQARAMEKGSR
YGRQMQEEVWQNAEVDALYRLAAAGVRVPQPYICFDGVLLMDLVVDADGGAAPRLNDVALSEAVALEFHAMLVNQVVRML
CAGIIHGDLSEYNILVDENGPVIIDLPQAIDAAANSTAAEMLERDVNNLRSYFSTFAPSLADSQYGKEIWALYESGLLQP
EQVLTGKVELDESLADVDAVLLQIEEAIKEDEIRRMCQ

Specific function: Unknown

COG id: COG1718

COG function: function code TD; Serine/threonine protein kinase involved in cell cycle control

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI23510356, Length=210, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI23510358, Length=127, Percent_Identity=33.0708661417323, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115532073, Length=215, Percent_Identity=29.3023255813954, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17556977, Length=223, Percent_Identity=27.8026905829596, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324693, Length=244, Percent_Identity=23.7704918032787, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24662811, Length=267, Percent_Identity=26.9662921348315, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356879, Length=267, Percent_Identity=26.9662921348315, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR000687
- InterPro:   IPR018935
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1 [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 30901; Mature: 30901

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPKRLTTLVEEGLVDEVIGQLMSGKEATVYIVRCGEHIRCAKVYKDAKQRSFRKATSY
CCCHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
QEGRKVKNSRQARAMEKGSRYGRQMQEEVWQNAEVDALYRLAAAGVRVPQPYICFDGVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
MDLVVDADGGAAPRLNDVALSEAVALEFHAMLVNQVVRMLCAGIIHGDLSEYNILVDENG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PVIIDLPQAIDAAANSTAAEMLERDVNNLRSYFSTFAPSLADSQYGKEIWALYESGLLQP
CEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
EQVLTGKVELDESLADVDAVLLQIEEAIKEDEIRRMCQ
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTPKRLTTLVEEGLVDEVIGQLMSGKEATVYIVRCGEHIRCAKVYKDAKQRSFRKATSY
CCCHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
QEGRKVKNSRQARAMEKGSRYGRQMQEEVWQNAEVDALYRLAAAGVRVPQPYICFDGVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
MDLVVDADGGAAPRLNDVALSEAVALEFHAMLVNQVVRMLCAGIIHGDLSEYNILVDENG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PVIIDLPQAIDAAANSTAAEMLERDVNNLRSYFSTFAPSLADSQYGKEIWALYESGLLQP
CEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
EQVLTGKVELDESLADVDAVLLQIEEAIKEDEIRRMCQ
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]