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The map label for this gene is ptxB [H]

Identifier: 71907455

GI number: 71907455

Start: 1963947

End: 1964828

Strand: Reverse

Name: ptxB [H]

Synonym: Daro_1826

Alternate gene names: 71907455

Gene position: 1964828-1963947 (Counterclockwise)

Preceding gene: 71907458

Following gene: 71907454

Centisome position: 43.65

GC content: 62.13

Gene sequence:

>882_bases
ATGAGCTTTTCTTCCCTGCGCCGCGCGGCGCTCAAGGGCGCGGTTGCCTGCGCTTTCGCTGCATCCGTTTCTGCCGCCCT
GCCGGCCCTCGCTTCCGACGCAGTCCTGCGCGTCTCGGCCATTCCGGACGAAGCCCCCACCGAACTGCAACGCAAGTTCG
CCCCGCTTGGCAAATACCTCGAAGCGCAGACCGGCATGAAGGTCATCTTCACGCCGGTATCCGACTACGCTGCTGTGGTC
GAATCGCTGGCCACGAAGAAGATCGACCTCGCCTGGCTCGGCGGCTTCACCTTCGTGCAAGCCAAGATCCGCACCAACGG
CACGGCCATCCCCATCGCCCAGCGCGAGGAGGATGCCAAGTTCACGTCCAAGTTCATCACCGCCGACCCGAGCATCAAGT
CGCTGGCCGACCTCAAGGGCAAGACCTTCGCTTTCGGCGCCCCGTCATCGACCTCGGGCAGCCTGATGCCTCGCTTCTTC
CTGCAGCAAGCCGGCCTGAATCCGGAAAAGGACTTCAAGAACGTCGCCTTCTCCGGCGCCCATGACGCCACCGTTGCCTT
CGTCGCGGCAGGCAAGGCTGAAGCCGGCGTATTGAACACCTCGGTCTGGGACAAGATGGTCGAGGCCAAGAAGGTCGATA
CCGACAAGGTCCGCGTCTTCGCCACCACCCCACCCTACTTCGACTACAACTGGACGGTCCGCGGCGACCTCGATCCGGTC
ATCATCAAGAAACTGACCGACGCCTTCCTGAAGCTCGACCCGGCCAACCCGGAACACAAGGAAATCCTCGCCCTGCAACG
TGCTGCCAAGTTCATTCCGACCAAGAAGGAAAACTACGACGGTATCGAAAAGGCCGCCCATTCGGCCGGCTTGCTGAAGT
AA

Upstream 100 bases:

>100_bases
CTGCGGTCTATGTACCGCATCGAATGGTTGGCGCCTCGGCGCCTTGTAAGCTGCCGTGACATCCGCACGGCGGCGGTTGC
TGGAAAAATCGGAGTACAAC

Downstream 100 bases:

>100_bases
ATCGGGCATGAGTTTCAGGCTGAACGGCGTGGGCTTGACCCACGCCAACGGTTTTGCCGCGCTGAAAGGCATCACGCTGC
TGGCGGAGAAAGGCGAGCGC

Product: phosphonate-binding periplasmic protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSFSSLRRAALKGAVACAFAASVSAALPALASDAVLRVSAIPDEAPTELQRKFAPLGKYLEAQTGMKVIFTPVSDYAAVV
ESLATKKIDLAWLGGFTFVQAKIRTNGTAIPIAQREEDAKFTSKFITADPSIKSLADLKGKTFAFGAPSSTSGSLMPRFF
LQQAGLNPEKDFKNVAFSGAHDATVAFVAAGKAEAGVLNTSVWDKMVEAKKVDTDKVRVFATTPPYFDYNWTVRGDLDPV
IIKKLTDAFLKLDPANPEHKEILALQRAAKFIPTKKENYDGIEKAAHSAGLLK

Sequences:

>Translated_293_residues
MSFSSLRRAALKGAVACAFAASVSAALPALASDAVLRVSAIPDEAPTELQRKFAPLGKYLEAQTGMKVIFTPVSDYAAVV
ESLATKKIDLAWLGGFTFVQAKIRTNGTAIPIAQREEDAKFTSKFITADPSIKSLADLKGKTFAFGAPSSTSGSLMPRFF
LQQAGLNPEKDFKNVAFSGAHDATVAFVAAGKAEAGVLNTSVWDKMVEAKKVDTDKVRVFATTPPYFDYNWTVRGDLDPV
IIKKLTDAFLKLDPANPEHKEILALQRAAKFIPTKKENYDGIEKAAHSAGLLK
>Mature_292_residues
SFSSLRRAALKGAVACAFAASVSAALPALASDAVLRVSAIPDEAPTELQRKFAPLGKYLEAQTGMKVIFTPVSDYAAVVE
SLATKKIDLAWLGGFTFVQAKIRTNGTAIPIAQREEDAKFTSKFITADPSIKSLADLKGKTFAFGAPSSTSGSLMPRFFL
QQAGLNPEKDFKNVAFSGAHDATVAFVAAGKAEAGVLNTSVWDKMVEAKKVDTDKVRVFATTPPYFDYNWTVRGDLDPVI
IKKLTDAFLKLDPANPEHKEILALQRAAKFIPTKKENYDGIEKAAHSAGLLK

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=238, Percent_Identity=27.3109243697479, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 31490; Mature: 31359

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSSLRRAALKGAVACAFAASVSAALPALASDAVLRVSAIPDEAPTELQRKFAPLGKYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHH
EAQTGMKVIFTPVSDYAAVVESLATKKIDLAWLGGFTFVQAKIRTNGTAIPIAQREEDAK
HHCCCCEEEEECHHHHHHHHHHHHHCCEEEEEECCEEEEEEEEECCCCEEECCCCCHHHH
FTSKFITADPSIKSLADLKGKTFAFGAPSSTSGSLMPRFFLQQAGLNPEKDFKNVAFSGA
HHHHHEECCCCHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCC
HDATVAFVAAGKAEAGVLNTSVWDKMVEAKKVDTDKVRVFATTPPYFDYNWTVRGDLDPV
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCHH
IIKKLTDAFLKLDPANPEHKEILALQRAAKFIPTKKENYDGIEKAAHSAGLLK
HHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SFSSLRRAALKGAVACAFAASVSAALPALASDAVLRVSAIPDEAPTELQRKFAPLGKYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHH
EAQTGMKVIFTPVSDYAAVVESLATKKIDLAWLGGFTFVQAKIRTNGTAIPIAQREEDAK
HHCCCCEEEEECHHHHHHHHHHHHHCCEEEEEECCEEEEEEEEECCCCEEECCCCCHHHH
FTSKFITADPSIKSLADLKGKTFAFGAPSSTSGSLMPRFFLQQAGLNPEKDFKNVAFSGA
HHHHHEECCCCHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCC
HDATVAFVAAGKAEAGVLNTSVWDKMVEAKKVDTDKVRVFATTPPYFDYNWTVRGDLDPV
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCHH
IIKKLTDAFLKLDPANPEHKEILALQRAAKFIPTKKENYDGIEKAAHSAGLLK
HHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]