Click here to switch to the map view.

The map label for this gene is ydjL [C]

Identifier: 71906980

GI number: 71906980

Start: 1464087

End: 1465211

Strand: Reverse

Name: ydjL [C]

Synonym: Daro_1348

Alternate gene names: 71906980

Gene position: 1465211-1464087 (Counterclockwise)

Preceding gene: 71906996

Following gene: 71906979

Centisome position: 32.55

GC content: 56.44

Gene sequence:

>1125_bases
ATGGGCCCTTCCGAGAATGGCACCATGCAAGCAGCTCGCGTGCATGGCGCTGGCGGGCAGTTTGAGATGGACAGCATCGA
ACGCCCCCGGATCAAACGTCCCACCGACGTAATAATCAATGTCAAAGCTAGCGGTGTCGTACCAAATTTACGCAACGTCA
TGAGCAACTATGGCGAACGCGCTTATCTGACCGTCCCTGAATTACCGGCGATCTATGGTCTAGATACTGCAGGCGTCATT
GCCGAAATTGGCAGTGGCGTCACGGGCCTCACGGTCGGTGATCGGGTTTATCTGAATCCCGGCCGCAGTTGCGGCACTTG
TCATGCCTGCCGTTGCGGCGAGCCAATCAACTGCAGCGCTTACACATTTCAGGGTTACTTTGGTTTTGGTCCTGCGTCGC
GCCAGATTTATCGAGAATATCCCTATGGCGGGTTCTGTGAATTCGCCACAGGCCCAGCTAATGGGCTCATCAAACTCCCC
GACACGATCAGTTTTGAACAAGCAGCACGCTTTGGCTATCTAGGTACTGCCTACTCCGGCTTGCGCAAAGCCGATGTTCG
TGCCGGCCGAACGGTCCTGATCAGCGGCGCCAGTGGAACGCTGGGATTGGGCGCAGTACAAATTGCACGTGCGATGGGTG
CCACCAGGATTCTATGCGTCGCACGCAACGCCGACTTGCTTGAACGTGTCCGCCTCTTGGACCCCCAGCGTATCCGCACC
TTCTCTTACGGCACAGGAGATCTTGCTACCTGGGCTCGTGATGAAACAGATGGAATCGGGGTGGACGCTGTACTCGATGC
CATCGGTCCGGGTGCCTCACATCAAGTGACGCTCGACTGCATTGCTGCCTTGAGACGGGGTGGAAAACTGGTGGAGGTTG
GCGCCATGTCCGACCCAATGCCGGTTAATCTGCACCAGATGATGTGCGCACAGGTCAGCCTAATCGGCTCACTCTGGTTC
TCGGTCGCCGAAGGACAGGAACTCGCTGCGATGGCCGATGCAGGAACCCTAGACCTGTCCATTTTCGAGCATCACCGCTT
CCCGCTCGAACGAGTGAACCAAGCCTTGGAACTTGCCGAAAAGAGGATCGGCGGTTTCATGAATGTCGTGATCACCCAAG
AATAA

Upstream 100 bases:

>100_bases
ATGTTCGATTTGAATGAGTGCAACGTTGCGACAAAAGCATGCCGCATCGGAGAGAACACCACACCCAATAGATAAATCAA
TCAAGCCAAAGGAGGCAAAT

Downstream 100 bases:

>100_bases
GGCCCCTGCCTTCATCAATCGCAGCCTTGCTCCTGAGCACACAGCACCACATTGCAATTTATCGATAATCCAATGAGAAA
ACTATGACACGACGTATCGT

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MGPSENGTMQAARVHGAGGQFEMDSIERPRIKRPTDVIINVKASGVVPNLRNVMSNYGERAYLTVPELPAIYGLDTAGVI
AEIGSGVTGLTVGDRVYLNPGRSCGTCHACRCGEPINCSAYTFQGYFGFGPASRQIYREYPYGGFCEFATGPANGLIKLP
DTISFEQAARFGYLGTAYSGLRKADVRAGRTVLISGASGTLGLGAVQIARAMGATRILCVARNADLLERVRLLDPQRIRT
FSYGTGDLATWARDETDGIGVDAVLDAIGPGASHQVTLDCIAALRRGGKLVEVGAMSDPMPVNLHQMMCAQVSLIGSLWF
SVAEGQELAAMADAGTLDLSIFEHHRFPLERVNQALELAEKRIGGFMNVVITQE

Sequences:

>Translated_374_residues
MGPSENGTMQAARVHGAGGQFEMDSIERPRIKRPTDVIINVKASGVVPNLRNVMSNYGERAYLTVPELPAIYGLDTAGVI
AEIGSGVTGLTVGDRVYLNPGRSCGTCHACRCGEPINCSAYTFQGYFGFGPASRQIYREYPYGGFCEFATGPANGLIKLP
DTISFEQAARFGYLGTAYSGLRKADVRAGRTVLISGASGTLGLGAVQIARAMGATRILCVARNADLLERVRLLDPQRIRT
FSYGTGDLATWARDETDGIGVDAVLDAIGPGASHQVTLDCIAALRRGGKLVEVGAMSDPMPVNLHQMMCAQVSLIGSLWF
SVAEGQELAAMADAGTLDLSIFEHHRFPLERVNQALELAEKRIGGFMNVVITQE
>Mature_373_residues
GPSENGTMQAARVHGAGGQFEMDSIERPRIKRPTDVIINVKASGVVPNLRNVMSNYGERAYLTVPELPAIYGLDTAGVIA
EIGSGVTGLTVGDRVYLNPGRSCGTCHACRCGEPINCSAYTFQGYFGFGPASRQIYREYPYGGFCEFATGPANGLIKLPD
TISFEQAARFGYLGTAYSGLRKADVRAGRTVLISGASGTLGLGAVQIARAMGATRILCVARNADLLERVRLLDPQRIRTF
SYGTGDLATWARDETDGIGVDAVLDAIGPGASHQVTLDCIAALRRGGKLVEVGAMSDPMPVNLHQMMCAQVSLIGSLWFS
VAEGQELAAMADAGTLDLSIFEHHRFPLERVNQALELAEKRIGGFMNVVITQE

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=352, Percent_Identity=26.1363636363636, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194239674, Length=359, Percent_Identity=28.133704735376, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI13236495, Length=359, Percent_Identity=28.133704735376, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4501929, Length=355, Percent_Identity=26.1971830985915, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4501933, Length=372, Percent_Identity=25.2688172043011, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI34577061, Length=358, Percent_Identity=25.4189944134078, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788075, Length=357, Percent_Identity=24.0896358543417, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082125, Length=333, Percent_Identity=29.1291291291291, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790045, Length=324, Percent_Identity=25.6172839506173, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788073, Length=287, Percent_Identity=25.7839721254355, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786825, Length=410, Percent_Identity=24.1463414634146, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787863, Length=173, Percent_Identity=28.3236994219653, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788407, Length=200, Percent_Identity=29, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562878, Length=214, Percent_Identity=29.4392523364486, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=341, Percent_Identity=25.2199413489736, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=208, Percent_Identity=29.3269230769231, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=362, Percent_Identity=25.9668508287293, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319955, Length=338, Percent_Identity=24.5562130177515, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6322619, Length=338, Percent_Identity=24.5562130177515, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=210, Percent_Identity=32.8571428571429, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=199, Percent_Identity=34.6733668341709, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=367, Percent_Identity=23.7057220708447, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=210, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319258, Length=216, Percent_Identity=26.8518518518519, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=199, Percent_Identity=30.6532663316583, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137530, Length=305, Percent_Identity=28.5245901639344, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17737897, Length=151, Percent_Identity=37.0860927152318, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45550770, Length=160, Percent_Identity=31.25, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221457811, Length=160, Percent_Identity=31.25, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45551930, Length=160, Percent_Identity=31.25, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 39927; Mature: 39796

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPSENGTMQAARVHGAGGQFEMDSIERPRIKRPTDVIINVKASGVVPNLRNVMSNYGER
CCCCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCE
AYLTVPELPAIYGLDTAGVIAEIGSGVTGLTVGDRVYLNPGRSCGTCHACRCGEPINCSA
EEEECCCCCCEECCCHHHHHHHHCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCE
YTFQGYFGFGPASRQIYREYPYGGFCEFATGPANGLIKLPDTISFEQAARFGYLGTAYSG
EEECCEECCCCHHHHHHHHCCCCCEEECCCCCCCCEEECCCCCCHHHHHHHCCCHHHHHH
LRKADVRAGRTVLISGASGTLGLGAVQIARAMGATRILCVARNADLLERVRLLDPQRIRT
HHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCCHHHEE
FSYGTGDLATWARDETDGIGVDAVLDAIGPGASHQVTLDCIAALRRGGKLVEVGAMSDPM
EECCCCCHHHCCCCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEEEECCCCCCC
PVNLHQMMCAQVSLIGSLWFSVAEGQELAAMADAGTLDLSIFEHHRFPLERVNQALELAE
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHCCCCHHHHHHHHHHHH
KRIGGFMNVVITQE
HHHCCEEEEEEECC
>Mature Secondary Structure 
GPSENGTMQAARVHGAGGQFEMDSIERPRIKRPTDVIINVKASGVVPNLRNVMSNYGER
CCCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCE
AYLTVPELPAIYGLDTAGVIAEIGSGVTGLTVGDRVYLNPGRSCGTCHACRCGEPINCSA
EEEECCCCCCEECCCHHHHHHHHCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCE
YTFQGYFGFGPASRQIYREYPYGGFCEFATGPANGLIKLPDTISFEQAARFGYLGTAYSG
EEECCEECCCCHHHHHHHHCCCCCEEECCCCCCCCEEECCCCCCHHHHHHHCCCHHHHHH
LRKADVRAGRTVLISGASGTLGLGAVQIARAMGATRILCVARNADLLERVRLLDPQRIRT
HHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCCHHHEE
FSYGTGDLATWARDETDGIGVDAVLDAIGPGASHQVTLDCIAALRRGGKLVEVGAMSDPM
EECCCCCHHHCCCCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEEEECCCCCCC
PVNLHQMMCAQVSLIGSLWFSVAEGQELAAMADAGTLDLSIFEHHRFPLERVNQALELAE
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHCCCCHHHHHHHHHHHH
KRIGGFMNVVITQE
HHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]