Click here to switch to the map view.

The map label for this gene is ubiG

Identifier: 71906866

GI number: 71906866

Start: 1331954

End: 1332652

Strand: Reverse

Name: ubiG

Synonym: Daro_1227

Alternate gene names: 71906866

Gene position: 1332652-1331954 (Counterclockwise)

Preceding gene: 71906867

Following gene: 71906865

Centisome position: 29.61

GC content: 56.8

Gene sequence:

>699_bases
ATGCTTAACGCCGACCAAGCCGAACTGGATAAATTTGGTGAACTTGCCCACCGCTGGTGGGATCCGAACAGCGAATTCAA
GCCGCTGCACGATATCAACCCGCTCCGCATCGACTGGATCGATCAGGCGATCAGTCTGGCTGGCAAACGCGTTCTGGACG
TTGGCTGTGGTGGAGGCCTGCTGTCTGAAGGCATGGCTGTTCGTGGCGCAAATGTGACTGGCATTGACCTCTCCGAGAAA
CCATTGGGCGTGGCCAAGCTCCACCTGCTGGAAACCGGCCAGAAGGTCGATTACCGCAAGATTTCCGTCGAGGAACTGGC
CGAACAGATGCCCGGTGAATTTGATGCTGTCACCTGCCTGGAAATGCTCGAACACGTTCCCAATCCATCCAGCGTCATCA
CGGCCTGCGCCCGCCTGGTCAAGCCGGGTGGCCAGGTTTTCCTGTCCACGCTCAACCGTAACCCGAAATCCTACCTGTTT
GCAGTCATCGGAGCCGAGTACGTGCTGCAGATGCTGCCCAAGGGAACGCACGATTACGCCAGGTTCATCAAGCCATCAGA
GCTCGCCCGCTGGGCGAAGATGGCCAACCTTGAACCTGAAGAACTTGTCGGCATGAGCTACAACCCACTGACCAAGAAGT
ACTCACTCGGCAAAGACACCAGCGTCAATTACCTGATGCGCACCATCCGGCATGTTTGA

Upstream 100 bases:

>100_bases
ACATCGAAGTCATCGGCACCAAGTAATCGGCCGTCGCTTCACCGAAAAGCCCTGCCTTGGCAGGGCTTTTTCTTTTCCGT
CAATTGAACAGATAAAAGCC

Downstream 100 bases:

>100_bases
TGCTGTTCTGTTCGACCTGGATGGCACCTTGGCCGACACGGCGCCCGACCTGGGCGAGTCGGTCAACATTCTGCTGCTGG
AGGAAGGACGACTGCAGATC

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MLNADQAELDKFGELAHRWWDPNSEFKPLHDINPLRIDWIDQAISLAGKRVLDVGCGGGLLSEGMAVRGANVTGIDLSEK
PLGVAKLHLLETGQKVDYRKISVEELAEQMPGEFDAVTCLEMLEHVPNPSSVITACARLVKPGGQVFLSTLNRNPKSYLF
AVIGAEYVLQMLPKGTHDYARFIKPSELARWAKMANLEPEELVGMSYNPLTKKYSLGKDTSVNYLMRTIRHV

Sequences:

>Translated_232_residues
MLNADQAELDKFGELAHRWWDPNSEFKPLHDINPLRIDWIDQAISLAGKRVLDVGCGGGLLSEGMAVRGANVTGIDLSEK
PLGVAKLHLLETGQKVDYRKISVEELAEQMPGEFDAVTCLEMLEHVPNPSSVITACARLVKPGGQVFLSTLNRNPKSYLF
AVIGAEYVLQMLPKGTHDYARFIKPSELARWAKMANLEPEELVGMSYNPLTKKYSLGKDTSVNYLMRTIRHV
>Mature_232_residues
MLNADQAELDKFGELAHRWWDPNSEFKPLHDINPLRIDWIDQAISLAGKRVLDVGCGGGLLSEGMAVRGANVTGIDLSEK
PLGVAKLHLLETGQKVDYRKISVEELAEQMPGEFDAVTCLEMLEHVPNPSSVITACARLVKPGGQVFLSTLNRNPKSYLF
AVIGAEYVLQMLPKGTHDYARFIKPSELARWAKMANLEPEELVGMSYNPLTKKYSLGKDTSVNYLMRTIRHV

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=244, Percent_Identity=33.6065573770492, Blast_Score=167, Evalue=9e-42,
Organism=Escherichia coli, GI1788564, Length=227, Percent_Identity=57.2687224669604, Blast_Score=278, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI115533050, Length=240, Percent_Identity=31.25, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6324476, Length=240, Percent_Identity=32.5, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281365311, Length=245, Percent_Identity=31.8367346938775, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24585589, Length=204, Percent_Identity=36.2745098039216, Blast_Score=130, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_DECAR (Q47GP8)

Other databases:

- EMBL:   CP000089
- RefSeq:   YP_284453.1
- ProteinModelPortal:   Q47GP8
- STRING:   Q47GP8
- GeneID:   3569411
- GenomeReviews:   CP000089_GR
- KEGG:   dar:Daro_1227
- NMPDR:   fig|159087.4.peg.891
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- ProtClustDB:   PRK05134
- BioCyc:   DARO159087:DARO_1227-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 25806; Mature: 25806

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNADQAELDKFGELAHRWWDPNSEFKPLHDINPLRIDWIDQAISLAGKRVLDVGCGGGL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHH
LSEGMAVRGANVTGIDLSEKPLGVAKLHLLETGQKVDYRKISVEELAEQMPGEFDAVTCL
HHCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHCCCHHHHHHHCCCCCHHHHHH
EMLEHVPNPSSVITACARLVKPGGQVFLSTLNRNPKSYLFAVIGAEYVLQMLPKGTHDYA
HHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
RFIKPSELARWAKMANLEPEELVGMSYNPLTKKYSLGKDTSVNYLMRTIRHV
HHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLNADQAELDKFGELAHRWWDPNSEFKPLHDINPLRIDWIDQAISLAGKRVLDVGCGGGL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHH
LSEGMAVRGANVTGIDLSEKPLGVAKLHLLETGQKVDYRKISVEELAEQMPGEFDAVTCL
HHCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHCCCHHHHHHHCCCCCHHHHHH
EMLEHVPNPSSVITACARLVKPGGQVFLSTLNRNPKSYLFAVIGAEYVLQMLPKGTHDYA
HHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
RFIKPSELARWAKMANLEPEELVGMSYNPLTKKYSLGKDTSVNYLMRTIRHV
HHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA