Click here to switch to the map view.

The map label for this gene is btr [H]

Identifier: 71906686

GI number: 71906686

Start: 1148436

End: 1149179

Strand: Reverse

Name: btr [H]

Synonym: Daro_1047

Alternate gene names: 71906686

Gene position: 1149179-1148436 (Counterclockwise)

Preceding gene: 71906697

Following gene: 71906681

Centisome position: 25.53

GC content: 56.05

Gene sequence:

>744_bases
ATGGCACAAACACACCCATTAAATCAGGAAATCTCGCTATCTGTCATCAAGACAGCCTGCTCCAATTGCAACCTGCGCGA
ACTATGCCTGCCATTTGGGCTCAGCATTGAAGAACTGGAGCGCCTCGACGACCTGGTTTCGACTCGTCGCCGCATAAAAC
GCGGCGACCATCTTTACCGCGCCGGTGAAGGCTTTGACGCGATTTACGCTATCCGCAGCGGTTTTTTCAAGACCGATGTG
CTGCTTGAAGATGGCCGTGACCAGGTCACTGGTTTCCAGATGGCTGGCGAGCTGCTCGGGCTGGATGGTATCAGCACCGA
ATACCACACCTGCAATGCCATCGCGCTCGAAGACAGCGAAATTTGTTCGATTCCGTTCTCGCGACTGGAAGGCCTGTCGC
GCGAAATCCACACGCTGCAACACCACTTCCACAAGGTCATGAGTCGGGAAATCGTTCGCGATCATGGTGTGATGATGCTG
CTCGGCACCATGCGCGCCGAGGAGCGACTGGCCGCTTTCCTGCTCAATCTGTCGCAACGCTTCACGGCGCGCGGCTTCTC
GCATGCCGAGTTCTACCTGCGCATGACCCGCGAGGAAATCGGTAGCTATCTCGGACTGAAGCTGGAAACCGTCTCCCGTG
CCTTCTCGAAATTTCAGGAAGAAGGCCACATCGCCGTTCAGCAGAAACACATCCGGATTTTGAACGTCAATGGGCTGAAG
GCCCTGATGAGCCACCGCAGCTGA

Upstream 100 bases:

>100_bases
TGTTGCGAAGTTCATTAGGCAAGCCATTAAAATTTGTTCGAATTATGTTCGGATGGCATGCTTTTGCGGTTGACTTGGAT
CAAGCTAACGCAGGTTGCCA

Downstream 100 bases:

>100_bases
CGCTTTACCAACGCAGTCTTGCCAGTTCTGCGGCCCGTTCGACCAGCCTGAACAGCAGCGCCTCGGCTTTGATGCGGGCC
GGTGTCGCGCCCCCTGTCGA

Product: cyclic nucleotide-binding: regulatory protein, Crp

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MAQTHPLNQEISLSVIKTACSNCNLRELCLPFGLSIEELERLDDLVSTRRRIKRGDHLYRAGEGFDAIYAIRSGFFKTDV
LLEDGRDQVTGFQMAGELLGLDGISTEYHTCNAIALEDSEICSIPFSRLEGLSREIHTLQHHFHKVMSREIVRDHGVMML
LGTMRAEERLAAFLLNLSQRFTARGFSHAEFYLRMTREEIGSYLGLKLETVSRAFSKFQEEGHIAVQQKHIRILNVNGLK
ALMSHRS

Sequences:

>Translated_247_residues
MAQTHPLNQEISLSVIKTACSNCNLRELCLPFGLSIEELERLDDLVSTRRRIKRGDHLYRAGEGFDAIYAIRSGFFKTDV
LLEDGRDQVTGFQMAGELLGLDGISTEYHTCNAIALEDSEICSIPFSRLEGLSREIHTLQHHFHKVMSREIVRDHGVMML
LGTMRAEERLAAFLLNLSQRFTARGFSHAEFYLRMTREEIGSYLGLKLETVSRAFSKFQEEGHIAVQQKHIRILNVNGLK
ALMSHRS
>Mature_246_residues
AQTHPLNQEISLSVIKTACSNCNLRELCLPFGLSIEELERLDDLVSTRRRIKRGDHLYRAGEGFDAIYAIRSGFFKTDVL
LEDGRDQVTGFQMAGELLGLDGISTEYHTCNAIALEDSEICSIPFSRLEGLSREIHTLQHHFHKVMSREIVRDHGVMMLL
GTMRAEERLAAFLLNLSQRFTARGFSHAEFYLRMTREEIGSYLGLKLETVSRAFSKFQEEGHIAVQQKHIRILNVNGLKA
LMSHRS

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=226, Percent_Identity=44.6902654867257, Blast_Score=210, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28110; Mature: 27979

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTHPLNQEISLSVIKTACSNCNLRELCLPFGLSIEELERLDDLVSTRRRIKRGDHLYR
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHEE
AGEGFDAIYAIRSGFFKTDVLLEDGRDQVTGFQMAGELLGLDGISTEYHTCNAIALEDSE
CCCCHHHHHHHHHCCHHHHHEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCC
ICSIPFSRLEGLSREIHTLQHHFHKVMSREIVRDHGVMMLLGTMRAEERLAAFLLNLSQR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
FTARGFSHAEFYLRMTREEIGSYLGLKLETVSRAFSKFQEEGHIAVQQKHIRILNVNGLK
HHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCEEEEECCHHH
ALMSHRS
HHHCCCC
>Mature Secondary Structure 
AQTHPLNQEISLSVIKTACSNCNLRELCLPFGLSIEELERLDDLVSTRRRIKRGDHLYR
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHEE
AGEGFDAIYAIRSGFFKTDVLLEDGRDQVTGFQMAGELLGLDGISTEYHTCNAIALEDSE
CCCCHHHHHHHHHCCHHHHHEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCC
ICSIPFSRLEGLSREIHTLQHHFHKVMSREIVRDHGVMMLLGTMRAEERLAAFLLNLSQR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
FTARGFSHAEFYLRMTREEIGSYLGLKLETVSRAFSKFQEEGHIAVQQKHIRILNVNGLK
HHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCEEEEECCHHH
ALMSHRS
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]