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The map label for this gene is serC [H]

Identifier: 71906623

GI number: 71906623

Start: 1075844

End: 1076989

Strand: Reverse

Name: serC [H]

Synonym: Daro_0984

Alternate gene names: 71906623

Gene position: 1076989-1075844 (Counterclockwise)

Preceding gene: 71906624

Following gene: 71906617

Centisome position: 23.93

GC content: 58.03

Gene sequence:

>1146_bases
ATGAGCCTGCTACACTCAAACCTGCTGAATGGCCTGAACTTTTCCGGTGGGCCGGGCGTACTGCCGGAAAGCGTGTTGCA
ACAGGTGCAAGACTCCATCCTGGCCGTTCCTGAGGTCGGGCTGTCGATTCTTGGCATCAGCCATCGCTCGGACTGGTTTG
CTACCGTGGTGGCCGAACTGGAAGACAACGTTCGGCAGTTACTTAAGCTGCCGAAAAATTATCACGTGCTATTCCTTCAA
GGTGGCGCGACACAGCAATTTTCCATGCTGCCGATGGCCCTTCTGGCCGGCAAGACACACCCGGCAGAATACCTGCACAC
TGGCTACTGGAGCGGCAAGGCACTGCCCGAAGCCCGACGCGAAGGCCCGGTACGCGTAGTATGGAGCGGCGAATCCTGCG
GCTTTGGGCGCCTGCCTGCTGACGAGGAACTGGATTTCCACGCCGATGCTCCGTACATCCATTACGTTTCGAACGAGACT
GTTGAAGGGCTGCAGTTTCATCGGGTTCTGGGACGCGACGACGTGCCGCGCATCTGCGACATGTCTTCCGACTTTCTCTC
AGCCCCCGGCGACTTCGAGCGCTTTTCGATGATCTATGCCCACGCGCAAAAGAATATCGGACCAGCCGGCGTCACCGTGG
TGGTGGTCAAGGATGAACTGCTCAAGGACGCCCCGGATAACCTGCCCGGCTTTCTCGACTACCGCACCCAGATCGAAGCC
CATTCGATCTACAACACGCCGCCAGTGTTTTCCATCTACGTCGTCCTGCTGGTAACCCGCTGGCTACGCGACCAGATTGG
CGGCCTGGCCGCCATGGATGCCATCAACACGCGCAAGGCCGAGACCTTGTATCAAGCCCTGGACGAAAGCAACGCCTTTT
ACGCCGGAAAAGCTGCCCGCGCCGACCGTTCCAAAATGAATGTTTCCTTCAACCTGCCGACTCCGGCGCTGGAGGCGGAA
TTTATCGCCAGCGCATTGGCCGCCGGATTTTCTGGTCTGGCCGGGCATCGCAGCATCGGCGGCATTCGAGCCTCACTCTA
TAACGGGCTTGAGTTATCAGCCGTCGAGAAACTGGCTGATTTCATGGCGAACTTCCGATCACATCACCTGCCGTTGGTGG
CAGGTGTAGGAAAAGGAAATCATTAA

Upstream 100 bases:

>100_bases
TGGACCCGGAAGACATCTTCCCCTACAAACAAGTCCATATGCGCAAGGTCAGGCAGGCTTTTGAAGACTTTCTATTCAGC
CTGACAACAGAGACCGCCAA

Downstream 100 bases:

>100_bases
CCCGCTGCTGTACGCGACGCCTGCACCCAAGTGGCTAGTGACGGCTGCTGCAAGAGTCGAGTCAGCAGATCGAACGCTGC
ATCAAGGTGGAGAGCGGCTG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSLLHSNLLNGLNFSGGPGVLPESVLQQVQDSILAVPEVGLSILGISHRSDWFATVVAELEDNVRQLLKLPKNYHVLFLQ
GGATQQFSMLPMALLAGKTHPAEYLHTGYWSGKALPEARREGPVRVVWSGESCGFGRLPADEELDFHADAPYIHYVSNET
VEGLQFHRVLGRDDVPRICDMSSDFLSAPGDFERFSMIYAHAQKNIGPAGVTVVVVKDELLKDAPDNLPGFLDYRTQIEA
HSIYNTPPVFSIYVVLLVTRWLRDQIGGLAAMDAINTRKAETLYQALDESNAFYAGKAARADRSKMNVSFNLPTPALEAE
FIASALAAGFSGLAGHRSIGGIRASLYNGLELSAVEKLADFMANFRSHHLPLVAGVGKGNH

Sequences:

>Translated_381_residues
MSLLHSNLLNGLNFSGGPGVLPESVLQQVQDSILAVPEVGLSILGISHRSDWFATVVAELEDNVRQLLKLPKNYHVLFLQ
GGATQQFSMLPMALLAGKTHPAEYLHTGYWSGKALPEARREGPVRVVWSGESCGFGRLPADEELDFHADAPYIHYVSNET
VEGLQFHRVLGRDDVPRICDMSSDFLSAPGDFERFSMIYAHAQKNIGPAGVTVVVVKDELLKDAPDNLPGFLDYRTQIEA
HSIYNTPPVFSIYVVLLVTRWLRDQIGGLAAMDAINTRKAETLYQALDESNAFYAGKAARADRSKMNVSFNLPTPALEAE
FIASALAAGFSGLAGHRSIGGIRASLYNGLELSAVEKLADFMANFRSHHLPLVAGVGKGNH
>Mature_380_residues
SLLHSNLLNGLNFSGGPGVLPESVLQQVQDSILAVPEVGLSILGISHRSDWFATVVAELEDNVRQLLKLPKNYHVLFLQG
GATQQFSMLPMALLAGKTHPAEYLHTGYWSGKALPEARREGPVRVVWSGESCGFGRLPADEELDFHADAPYIHYVSNETV
EGLQFHRVLGRDDVPRICDMSSDFLSAPGDFERFSMIYAHAQKNIGPAGVTVVVVKDELLKDAPDNLPGFLDYRTQIEAH
SIYNTPPVFSIYVVLLVTRWLRDQIGGLAAMDAINTRKAETLYQALDESNAFYAGKAARADRSKMNVSFNLPTPALEAEF
IASALAAGFSGLAGHRSIGGIRASLYNGLELSAVEKLADFMANFRSHHLPLVAGVGKGNH

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=363, Percent_Identity=43.2506887052342, Blast_Score=301, Evalue=7e-82,
Organism=Homo sapiens, GI10863955, Length=359, Percent_Identity=39.2757660167131, Blast_Score=259, Evalue=2e-69,
Organism=Escherichia coli, GI1787136, Length=361, Percent_Identity=41.5512465373961, Blast_Score=273, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17506897, Length=363, Percent_Identity=36.6391184573003, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6324758, Length=383, Percent_Identity=37.3368146214099, Blast_Score=222, Evalue=7e-59,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=40.495867768595, Blast_Score=274, Evalue=7e-74,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 41526; Mature: 41394

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLHSNLLNGLNFSGGPGVLPESVLQQVQDSILAVPEVGLSILGISHRSDWFATVVAEL
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
EDNVRQLLKLPKNYHVLFLQGGATQQFSMLPMALLAGKTHPAEYLHTGYWSGKALPEARR
HHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHC
EGPVRVVWSGESCGFGRLPADEELDFHADAPYIHYVSNETVEGLQFHRVLGRDDVPRICD
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHC
MSSDFLSAPGDFERFSMIYAHAQKNIGPAGVTVVVVKDELLKDAPDNLPGFLDYRTQIEA
CCCHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCCCCCCHHHHHEEEH
HSIYNTPPVFSIYVVLLVTRWLRDQIGGLAAMDAINTRKAETLYQALDESNAFYAGKAAR
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCHHH
ADRSKMNVSFNLPTPALEAEFIASALAAGFSGLAGHRSIGGIRASLYNGLELSAVEKLAD
CCCHHEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHCHHHHHHHCCCHHHHHHHHHH
FMANFRSHHLPLVAGVGKGNH
HHHHHHHCCCCEEEECCCCCC
>Mature Secondary Structure 
SLLHSNLLNGLNFSGGPGVLPESVLQQVQDSILAVPEVGLSILGISHRSDWFATVVAEL
CCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
EDNVRQLLKLPKNYHVLFLQGGATQQFSMLPMALLAGKTHPAEYLHTGYWSGKALPEARR
HHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHC
EGPVRVVWSGESCGFGRLPADEELDFHADAPYIHYVSNETVEGLQFHRVLGRDDVPRICD
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHC
MSSDFLSAPGDFERFSMIYAHAQKNIGPAGVTVVVVKDELLKDAPDNLPGFLDYRTQIEA
CCCHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCCCCCCHHHHHEEEH
HSIYNTPPVFSIYVVLLVTRWLRDQIGGLAAMDAINTRKAETLYQALDESNAFYAGKAAR
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCHHH
ADRSKMNVSFNLPTPALEAEFIASALAAGFSGLAGHRSIGGIRASLYNGLELSAVEKLAD
CCCHHEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHCHHHHHHHCCCHHHHHHHHHH
FMANFRSHHLPLVAGVGKGNH
HHHHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12835416 [H]