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The map label for this gene is hrcA

Identifier: 71906569

GI number: 71906569

Start: 1008651

End: 1009679

Strand: Reverse

Name: hrcA

Synonym: Daro_0930

Alternate gene names: 71906569

Gene position: 1009679-1008651 (Counterclockwise)

Preceding gene: 71906572

Following gene: 71906568

Centisome position: 22.43

GC content: 60.45

Gene sequence:

>1029_bases
ATGCTTGATGAACGCGCCCGCACCCTGCTCAAGACCCTGGTCGAACACTACGTTGCTGATGGACAGCCGGTGGGGTCACG
CGCGCTGTCCAAGTTTTCCGGCCTCGACCTGTCACCCGCCACCATCCGCAACGTGATGGCAGACCTTGAAGAGGCCGGTT
TTGTTGCCAGTCCGCACACATCGGCCGGGCGCATTCCGACAGCCCGCGGTTATCGCCTGTTCGTCGACAGTCTCCTCACC
GTGCAACCGCTTGAAGCCCGCCAGATGGGCGAGATGGAGGAGGCCCTGCACGGCCGTCCCGCGGGCCAGATCATCGCCAG
CGCCTCGCAACTGCTGTCCAGCCTGACCCATTTTGCCGGGGTGGTCATCGCACCGCGTCGCCAGAGCAGCCGGATTCGCC
AGATCGAATTCCTCAGCCTGTCGGAAAAACGCATCCTGCTGATCATCGTCACCGCCGATGGTGATGTGCAGAACCGCATC
GTCACCACCGACAAGGTCTATTCCCCAGCCGAGTTGGTCAGCGCAGCCAATTACCTGACCCAGAATTTTGCCGGCCTCGA
TTTCGAACAGATTCGTCATCGCCTGACTGTGGAAATCAAACAACTGCGCGACGACATCAAGCCCCTGATGGCCCTGGCGC
TTGATGCCGGCGATGCTGCCATGGCCGAAAACACAACGCCCTACGTCATCTCCGGCGAACGCAACCTGCTCGATGTCGAA
GAGCTGTCCTCCAACATGAAGCGTTTGCGCGAATTGTTCGATCTGTTTGAACAACGTTCCAGCCTGATGCGCCTGCTGGA
AATCTCCAACAGTGCTGAAGGCGTGCAAATCTTCATCGGTGGTGAATCGGGGATCGCCACGCTCGACGAATGCAGCGTCA
TTGCCGCCCCGTACACGGTGGATGGCCAGGTCGTCGGCTCGGTCGGCGTCATCGGACCAACCCGCATGGCCTACGAACGC
GTCATCCCCATCGTCGACATTACCGCCCGCCTGCTCTCCAGCGCCCTCTCCTACAAATCGGACAACTGA

Upstream 100 bases:

>100_bases
CGGGGGGAGCGGTAGGAAGCAAAGCCTCTATTCATGGGGTCGAATTCTTGCATAAAAAACGCGTTACGGCGCCGACTCCA
GTTTTTTGTACAATCCCCCC

Downstream 100 bases:

>100_bases
TGCCCCGTTTTCTCCCGGAACCGCCGCACCGTCACGGCAACCCGGCGACCACTGCGGTCGTCCTCGTCAATCTCGGCACA
CCGGATGCGCCGACGGCCCC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLDERARTLLKTLVEHYVADGQPVGSRALSKFSGLDLSPATIRNVMADLEEAGFVASPHTSAGRIPTARGYRLFVDSLLT
VQPLEARQMGEMEEALHGRPAGQIIASASQLLSSLTHFAGVVIAPRRQSSRIRQIEFLSLSEKRILLIIVTADGDVQNRI
VTTDKVYSPAELVSAANYLTQNFAGLDFEQIRHRLTVEIKQLRDDIKPLMALALDAGDAAMAENTTPYVISGERNLLDVE
ELSSNMKRLRELFDLFEQRSSLMRLLEISNSAEGVQIFIGGESGIATLDECSVIAAPYTVDGQVVGSVGVIGPTRMAYER
VIPIVDITARLLSSALSYKSDN

Sequences:

>Translated_342_residues
MLDERARTLLKTLVEHYVADGQPVGSRALSKFSGLDLSPATIRNVMADLEEAGFVASPHTSAGRIPTARGYRLFVDSLLT
VQPLEARQMGEMEEALHGRPAGQIIASASQLLSSLTHFAGVVIAPRRQSSRIRQIEFLSLSEKRILLIIVTADGDVQNRI
VTTDKVYSPAELVSAANYLTQNFAGLDFEQIRHRLTVEIKQLRDDIKPLMALALDAGDAAMAENTTPYVISGERNLLDVE
ELSSNMKRLRELFDLFEQRSSLMRLLEISNSAEGVQIFIGGESGIATLDECSVIAAPYTVDGQVVGSVGVIGPTRMAYER
VIPIVDITARLLSSALSYKSDN
>Mature_342_residues
MLDERARTLLKTLVEHYVADGQPVGSRALSKFSGLDLSPATIRNVMADLEEAGFVASPHTSAGRIPTARGYRLFVDSLLT
VQPLEARQMGEMEEALHGRPAGQIIASASQLLSSLTHFAGVVIAPRRQSSRIRQIEFLSLSEKRILLIIVTADGDVQNRI
VTTDKVYSPAELVSAANYLTQNFAGLDFEQIRHRLTVEIKQLRDDIKPLMALALDAGDAAMAENTTPYVISGERNLLDVE
ELSSNMKRLRELFDLFEQRSSLMRLLEISNSAEGVQIFIGGESGIATLDECSVIAAPYTVDGQVVGSVGVIGPTRMAYER
VIPIVDITARLLSSALSYKSDN

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_DECAR (Q47HJ5)

Other databases:

- EMBL:   CP000089
- RefSeq:   YP_284156.1
- HSSP:   Q9WZV5
- ProteinModelPortal:   Q47HJ5
- SMR:   Q47HJ5
- STRING:   Q47HJ5
- GeneID:   3570244
- GenomeReviews:   CP000089_GR
- KEGG:   dar:Daro_0930
- NMPDR:   fig|159087.4.peg.1317
- eggNOG:   COG1420
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- BioCyc:   DARO159087:DARO_0930-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF03444 DUF293; PF01628 HrcA

EC number: NA

Molecular weight: Translated: 37344; Mature: 37344

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDERARTLLKTLVEHYVADGQPVGSRALSKFSGLDLSPATIRNVMADLEEAGFVASPHT
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCC
SAGRIPTARGYRLFVDSLLTVQPLEARQMGEMEEALHGRPAGQIIASASQLLSSLTHFAG
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
VVIAPRRQSSRIRQIEFLSLSEKRILLIIVTADGDVQNRIVTTDKVYSPAELVSAANYLT
EEEECCCCCCHHHEEHEEEECCCEEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHH
QNFAGLDFEQIRHRLTVEIKQLRDDIKPLMALALDAGDAAMAENTTPYVISGERNLLDVE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEECCCCCCCCHH
ELSSNMKRLRELFDLFEQRSSLMRLLEISNSAEGVQIFIGGESGIATLDECSVIAAPYTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEECCEEE
DGQVVGSVGVIGPTRMAYERVIPIVDITARLLSSALSYKSDN
CCEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLDERARTLLKTLVEHYVADGQPVGSRALSKFSGLDLSPATIRNVMADLEEAGFVASPHT
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCC
SAGRIPTARGYRLFVDSLLTVQPLEARQMGEMEEALHGRPAGQIIASASQLLSSLTHFAG
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
VVIAPRRQSSRIRQIEFLSLSEKRILLIIVTADGDVQNRIVTTDKVYSPAELVSAANYLT
EEEECCCCCCHHHEEHEEEECCCEEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHH
QNFAGLDFEQIRHRLTVEIKQLRDDIKPLMALALDAGDAAMAENTTPYVISGERNLLDVE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEECCCCCCCCHH
ELSSNMKRLRELFDLFEQRSSLMRLLEISNSAEGVQIFIGGESGIATLDECSVIAAPYTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEECCEEE
DGQVVGSVGVIGPTRMAYERVIPIVDITARLLSSALSYKSDN
CCEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA