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The map label for this gene is xerD [H]

Identifier: 71906177

GI number: 71906177

Start: 595374

End: 596282

Strand: Reverse

Name: xerD [H]

Synonym: Daro_0537

Alternate gene names: 71906177

Gene position: 596282-595374 (Counterclockwise)

Preceding gene: 71906178

Following gene: 71906176

Centisome position: 13.25

GC content: 65.24

Gene sequence:

>909_bases
ATGAAAATAGCCTCCCAGGCTGACCTTTCCGAGATCGACAATTTCTGCGATGCCCTGTGGCTGGAAGACGGTCTGGCCAA
GGCGACGCTGGACAGCTATCGCTCCGATCTCAGCCGGCTGGCCCTGTGGCTGGCCAACAACGCGTCCGAACCGCTGCTCG
ACCTGCACGAAACGACGCTGACCGCCTTTATCGCCCATCTGGCCAAGCAAACCCGCGCTACCTCGCAAGCGCGCTACCTG
TCGACGCTGCGCCGTTTCTACCGCTGGCAACTTGGCCGTGGTCGCATCGTCGCCGACCCGACGCTCAAGCTGGCCAACCC
GAGCCGCCCGTCGCGCCTGCCCAAGGTGATGTCGGAGAAGCAGGTCGAAGCCCTGCTCGACGCCCCCGACCTCGACACCC
CGCTCGGCCTGCGCGACCGCGCCATGCTGGAAACCATCTACGCCACCGGCCTGCGCGTCTCGGAACTGGTCAATCTCAGG
TTGCACGAAGTCAGTCTGGCCGACGGCGTCCTGCGCGCCCTCGGCAAGGGCAGCAAGGAGCGTCTGGTGCCGCTCGGCCA
GCTGGCCATCGAGTGGATCAAGCGTTACCTGAATGAAGCCCGGCCGGACATCCTGAACGGCCAGCACAGCGACGACCTGT
TCATCACCGCCCGTGGCGGCGGCATGACTCGCCAGGCCTTCTGGCAACTGATCAAGCGCTACGCGCTGATCGCCGGCATC
GCCCCGGACAAGCTTTCCCCACACGTCCTACGCCATGCCTTCGCGACCCACTTGCTCAACCACGGCGCCGATCTGCGCGT
TGTTCAGCTCCTGCTCGGTCACGCCGACATCTCGACCACCCAGATTTACACCCACGTCGCCCGGGAACGCCTGAAGACCC
TGCACGCCGTGCATCATCCTCGCGGCTGA

Upstream 100 bases:

>100_bases
GTCCCCTGCCACCGCGTCGTCGCCACTGGCGGCGGACTGGGCGGTTTCTCCCGCGAACGGGGCGGTTTCCTGCTCGACGT
CAAACGCTGGTTGCTGACGC

Downstream 100 bases:

>100_bases
AAGAATACGCATGCCACCGATTGCCCTCAACGAAAGCGAAGTCGAATTCATCGCCATCCGTGCCCAAGGGGCGGGCGGCC
AGAACGTCAACAAGGTGTCG

Product: tyrosine recombinase XerD subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKIASQADLSEIDNFCDALWLEDGLAKATLDSYRSDLSRLALWLANNASEPLLDLHETTLTAFIAHLAKQTRATSQARYL
STLRRFYRWQLGRGRIVADPTLKLANPSRPSRLPKVMSEKQVEALLDAPDLDTPLGLRDRAMLETIYATGLRVSELVNLR
LHEVSLADGVLRALGKGSKERLVPLGQLAIEWIKRYLNEARPDILNGQHSDDLFITARGGGMTRQAFWQLIKRYALIAGI
APDKLSPHVLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKTLHAVHHPRG

Sequences:

>Translated_302_residues
MKIASQADLSEIDNFCDALWLEDGLAKATLDSYRSDLSRLALWLANNASEPLLDLHETTLTAFIAHLAKQTRATSQARYL
STLRRFYRWQLGRGRIVADPTLKLANPSRPSRLPKVMSEKQVEALLDAPDLDTPLGLRDRAMLETIYATGLRVSELVNLR
LHEVSLADGVLRALGKGSKERLVPLGQLAIEWIKRYLNEARPDILNGQHSDDLFITARGGGMTRQAFWQLIKRYALIAGI
APDKLSPHVLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKTLHAVHHPRG
>Mature_302_residues
MKIASQADLSEIDNFCDALWLEDGLAKATLDSYRSDLSRLALWLANNASEPLLDLHETTLTAFIAHLAKQTRATSQARYL
STLRRFYRWQLGRGRIVADPTLKLANPSRPSRLPKVMSEKQVEALLDAPDLDTPLGLRDRAMLETIYATGLRVSELVNLR
LHEVSLADGVLRALGKGSKERLVPLGQLAIEWIKRYLNEARPDILNGQHSDDLFITARGGGMTRQAFWQLIKRYALIAGI
APDKLSPHVLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKTLHAVHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=298, Percent_Identity=56.3758389261745, Blast_Score=318, Evalue=3e-88,
Organism=Escherichia coli, GI1790244, Length=297, Percent_Identity=35.6902356902357, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1790768, Length=172, Percent_Identity=31.3953488372093, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33824; Mature: 33824

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIASQADLSEIDNFCDALWLEDGLAKATLDSYRSDLSRLALWLANNASEPLLDLHETTL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
TAFIAHLAKQTRATSQARYLSTLRRFYRWQLGRGRIVADPTLKLANPSRPSRLPKVMSEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECCCCCCCHHHHHHHHHH
QVEALLDAPDLDTPLGLRDRAMLETIYATGLRVSELVNLRLHEVSLADGVLRALGKGSKE
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RLVPLGQLAIEWIKRYLNEARPDILNGQHSDDLFITARGGGMTRQAFWQLIKRYALIAGI
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
APDKLSPHVLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKTLHAVHHP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
RG
CC
>Mature Secondary Structure
MKIASQADLSEIDNFCDALWLEDGLAKATLDSYRSDLSRLALWLANNASEPLLDLHETTL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
TAFIAHLAKQTRATSQARYLSTLRRFYRWQLGRGRIVADPTLKLANPSRPSRLPKVMSEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECCCCCCCHHHHHHHHHH
QVEALLDAPDLDTPLGLRDRAMLETIYATGLRVSELVNLRLHEVSLADGVLRALGKGSKE
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RLVPLGQLAIEWIKRYLNEARPDILNGQHSDDLFITARGGGMTRQAFWQLIKRYALIAGI
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
APDKLSPHVLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKTLHAVHHP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
RG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]