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The map label for this gene is clpX [H]

Identifier: 71905873

GI number: 71905873

Start: 258754

End: 259836

Strand: Reverse

Name: clpX [H]

Synonym: Daro_0231

Alternate gene names: 71905873

Gene position: 259836-258754 (Counterclockwise)

Preceding gene: 71905877

Following gene: 71905867

Centisome position: 5.77

GC content: 60.85

Gene sequence:

>1083_bases
ATGACCAGATCGAGCTTCCCGAAAACGCCCGGCACGACTAGCATCCAAACATACCGTCCGAGGAGTTGCCCAATGCCCAC
CTTGCTCAAGCCCAGCGAAATCGTCCGCCGCCTTTCCGACCACGTGATCGGCCAGGACGACGCCAAGAAAACACTGGCTG
TCGCCATCTACGCCCATTTTCGCCGCATGGCGAATATCGCGGAAGACAGTGTTGAGCTGACCAAAAGCAACATCCTGCTG
ATTGGCCCGACCGGCACCGGCAAAACCCTGCTTTGCGAAACGCTGGCCCGCATCCTCGACGTCCCCTTCGTGACCGCCGA
TGCCACCTCGCTGGCCCAGACGCAATTTGTCGGCGACGAAATCGAAGCCATCCTGCATCGCCTACTCGACCGGGCCAACG
ACGACCTGGCACTCGCCCAGCGCGGCATCGTTTTCGTCGATGAAGTCGACAAGCTCAAGGCCGTCGGCGGCGAATCCCGC
GCCACCTCCGGCGAAAGCGTCCAGCACGCCCTGCTCAAGATCATGGAAGGCGCGCCGGTCCGCCTGAAGGATGGCCGCCA
TATCGACACCACCAATATCCTGTTCATCTGCGGCGGCGCCTTTGTCGGGCTCGACCACATCCTGACCAAGACGCACACCT
TTGGCTTTATCTCGACCGCCGAAGGCGACGACCAGAAAATCCTCGAACGCTTGAACGCCCGTGTCAAACCGACCGACCTG
CTCGAATTCGGTCTGATCCCCGAATTTGCCGGCCGCCTGCCGATCGTCACCCGCCTGCATGATCTGTCGCAGGACATGCT
GGTCCGCATCCTGACCGAGCCGAAAAACGCCATCTACAAGCAATTTCAGGCCATGCTGGCGGCCGATGGCGTCGACTTGC
AGGTAGAACCCAACGTTTTCCGCCAGATGGCTGAACTCGCCATCGAATACAAGGCCGGCGCCCGCAGCCTGCGCGGCATT
TTCGAGGAAATGATGGTCGACGTGATGTACGCCGTACCGGACAACCCGGCCATCGGGCGCGTCATCATCAGTTCGCTGTT
CGAAAGGCCAAAACTGGCCGCCGCCGAACCAAAGGCGAGCTGA

Upstream 100 bases:

>100_bases
CGGCCACCTCCCTTGGAGCAGTCTAGCAGCCTGCTCCGAACTTCGGAAAACAGACTTGCGCCACCCTGCGCTTCGCACAG
CGGACCACCGGGGCTCCTCA

Downstream 100 bases:

>100_bases
AGCGAAACCGCCGGGCGGGCACGGAATAATCAGCCGCCACGACAAATTGACTGGTTCGCCAATGGCAACCAGTTTGCGCT
ATGACTCGCCACGATCAGCT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTRSSFPKTPGTTSIQTYRPRSCPMPTLLKPSEIVRRLSDHVIGQDDAKKTLAVAIYAHFRRMANIAEDSVELTKSNILL
IGPTGTGKTLLCETLARILDVPFVTADATSLAQTQFVGDEIEAILHRLLDRANDDLALAQRGIVFVDEVDKLKAVGGESR
ATSGESVQHALLKIMEGAPVRLKDGRHIDTTNILFICGGAFVGLDHILTKTHTFGFISTAEGDDQKILERLNARVKPTDL
LEFGLIPEFAGRLPIVTRLHDLSQDMLVRILTEPKNAIYKQFQAMLAADGVDLQVEPNVFRQMAELAIEYKAGARSLRGI
FEEMMVDVMYAVPDNPAIGRVIISSLFERPKLAAAEPKAS

Sequences:

>Translated_360_residues
MTRSSFPKTPGTTSIQTYRPRSCPMPTLLKPSEIVRRLSDHVIGQDDAKKTLAVAIYAHFRRMANIAEDSVELTKSNILL
IGPTGTGKTLLCETLARILDVPFVTADATSLAQTQFVGDEIEAILHRLLDRANDDLALAQRGIVFVDEVDKLKAVGGESR
ATSGESVQHALLKIMEGAPVRLKDGRHIDTTNILFICGGAFVGLDHILTKTHTFGFISTAEGDDQKILERLNARVKPTDL
LEFGLIPEFAGRLPIVTRLHDLSQDMLVRILTEPKNAIYKQFQAMLAADGVDLQVEPNVFRQMAELAIEYKAGARSLRGI
FEEMMVDVMYAVPDNPAIGRVIISSLFERPKLAAAEPKAS
>Mature_359_residues
TRSSFPKTPGTTSIQTYRPRSCPMPTLLKPSEIVRRLSDHVIGQDDAKKTLAVAIYAHFRRMANIAEDSVELTKSNILLI
GPTGTGKTLLCETLARILDVPFVTADATSLAQTQFVGDEIEAILHRLLDRANDDLALAQRGIVFVDEVDKLKAVGGESRA
TSGESVQHALLKIMEGAPVRLKDGRHIDTTNILFICGGAFVGLDHILTKTHTFGFISTAEGDDQKILERLNARVKPTDLL
EFGLIPEFAGRLPIVTRLHDLSQDMLVRILTEPKNAIYKQFQAMLAADGVDLQVEPNVFRQMAELAIEYKAGARSLRGIF
EEMMVDVMYAVPDNPAIGRVIISSLFERPKLAAAEPKAS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=305, Percent_Identity=43.2786885245902, Blast_Score=240, Evalue=2e-63,
Organism=Escherichia coli, GI1786642, Length=365, Percent_Identity=46.027397260274, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1790366, Length=104, Percent_Identity=42.3076923076923, Blast_Score=95, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=293, Percent_Identity=40.9556313993174, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71982905, Length=293, Percent_Identity=40.9556313993174, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71988663, Length=387, Percent_Identity=32.8165374677003, Blast_Score=190, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI71988660, Length=243, Percent_Identity=34.5679012345679, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6319704, Length=432, Percent_Identity=32.8703703703704, Blast_Score=213, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24648291, Length=293, Percent_Identity=42.6621160409556, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24648289, Length=293, Percent_Identity=42.6621160409556, Blast_Score=236, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 39544; Mature: 39413

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSSFPKTPGTTSIQTYRPRSCPMPTLLKPSEIVRRLSDHVIGQDDAKKTLAVAIYAHF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RRMANIAEDSVELTKSNILLIGPTGTGKTLLCETLARILDVPFVTADATSLAQTQFVGDE
HHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHH
IEAILHRLLDRANDDLALAQRGIVFVDEVDKLKAVGGESRATSGESVQHALLKIMEGAPV
HHHHHHHHHHCCCCCHHHHHCCEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCE
RLKDGRHIDTTNILFICGGAFVGLDHILTKTHTFGFISTAEGDDQKILERLNARVKPTDL
EECCCCEECCCCEEEEECCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCHHH
LEFGLIPEFAGRLPIVTRLHDLSQDMLVRILTEPKNAIYKQFQAMLAADGVDLQVEPNVF
HHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHH
RQMAELAIEYKAGARSLRGIFEEMMVDVMYAVPDNPAIGRVIISSLFERPKLAAAEPKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TRSSFPKTPGTTSIQTYRPRSCPMPTLLKPSEIVRRLSDHVIGQDDAKKTLAVAIYAHF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RRMANIAEDSVELTKSNILLIGPTGTGKTLLCETLARILDVPFVTADATSLAQTQFVGDE
HHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHH
IEAILHRLLDRANDDLALAQRGIVFVDEVDKLKAVGGESRATSGESVQHALLKIMEGAPV
HHHHHHHHHHCCCCCHHHHHCCEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCE
RLKDGRHIDTTNILFICGGAFVGLDHILTKTHTFGFISTAEGDDQKILERLNARVKPTDL
EECCCCEECCCCEEEEECCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCHHH
LEFGLIPEFAGRLPIVTRLHDLSQDMLVRILTEPKNAIYKQFQAMLAADGVDLQVEPNVF
HHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHH
RQMAELAIEYKAGARSLRGIFEEMMVDVMYAVPDNPAIGRVIISSLFERPKLAAAEPKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA