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The map label for this gene is nahD [H]

Identifier: 71905736

GI number: 71905736

Start: 110924

End: 111529

Strand: Reverse

Name: nahD [H]

Synonym: Daro_0094

Alternate gene names: 71905736

Gene position: 111529-110924 (Counterclockwise)

Preceding gene: 71905737

Following gene: 71905735

Centisome position: 2.48

GC content: 63.37

Gene sequence:

>606_bases
ATGTCAGAACCTATTGATTTCTACTTCGATTTTTCCAGCCCCTACGGCTACCTGATGAGCGAGAAGATCGATGCCGTGGC
AGCAAAGCATGGCCGCAAGGTGCGCTGGCATCCTGTACTGCTCGGCGTGATTTTCCAGGCCACCGGCTCCCGCCCCCCGG
CTGACGGTGTCAGCAGCAAGAGCACCTACATGTTCCACGATTTCCACCGCTCGGCCCGCCACATGGGCATCCCCTACAAC
CCGCCGAGCCGCTTCCCGCTGCCGACGCAGAACGCCGCCCGCGCCTACTACTGGCTGCACGGCCAGGACTGCGCGCTGGC
CCGTCAGTTTGCCCACGCCGTCTATCGTGGCTTCTTCGTCGACGACCTCGATGTGTCCTCGCCGGACACCGTGCTCGACA
TTGCAGCCAAGCTCGGCATCGACCGTGCCCAACTGGCTACCGCGCTGCAGGCGCCCGAGATCAAGGCCCGCCTCAAGGAC
GAATGCGACAAGGCACTGGCCGCCGGCGTCTTCGGTTCGCCGCACGTGATCATCGACGGCGAAGCCTTCTTCGGCGCCGA
CCGTCTGCCGCAGATCGAACACTGGCTGGAAACAGGCGGTTTTTAA

Upstream 100 bases:

>100_bases
GCCCCGTTGCCGGAAGCAACATCAAGGTTGTCTACGTTCGTCGAACACCAAGCAAATCAGGTCACTGATCCCAACAAAAC
AAACACTGTGAGACAAAGAT

Downstream 100 bases:

>100_bases
GCGGCAATTGTCCGAGACAACCATGAAACGAATCTGCGTCTTCTGTGGCTCCAACGCCGGCCACAACCCGCTCTACCGTA
CCGAGGCGGAAAAGCTCGGC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: HCCA isomerase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSEPIDFYFDFSSPYGYLMSEKIDAVAAKHGRKVRWHPVLLGVIFQATGSRPPADGVSSKSTYMFHDFHRSARHMGIPYN
PPSRFPLPTQNAARAYYWLHGQDCALARQFAHAVYRGFFVDDLDVSSPDTVLDIAAKLGIDRAQLATALQAPEIKARLKD
ECDKALAAGVFGSPHVIIDGEAFFGADRLPQIEHWLETGGF

Sequences:

>Translated_201_residues
MSEPIDFYFDFSSPYGYLMSEKIDAVAAKHGRKVRWHPVLLGVIFQATGSRPPADGVSSKSTYMFHDFHRSARHMGIPYN
PPSRFPLPTQNAARAYYWLHGQDCALARQFAHAVYRGFFVDDLDVSSPDTVLDIAAKLGIDRAQLATALQAPEIKARLKD
ECDKALAAGVFGSPHVIIDGEAFFGADRLPQIEHWLETGGF
>Mature_200_residues
SEPIDFYFDFSSPYGYLMSEKIDAVAAKHGRKVRWHPVLLGVIFQATGSRPPADGVSSKSTYMFHDFHRSARHMGIPYNP
PSRFPLPTQNAARAYYWLHGQDCALARQFAHAVYRGFFVDDLDVSSPDTVLDIAAKLGIDRAQLATALQAPEIKARLKDE
CDKALAAGVFGSPHVIIDGEAFFGADRLPQIEHWLETGGF

Specific function: Catalyzes the isomerization of 2-hydroxychromene-2- carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). The reaction is reversible [H]

COG id: COG3917

COG function: function code Q; 2-hydroxychromene-2-carboxylate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17538137, Length=196, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17539520, Length=204, Percent_Identity=25, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR014440
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: NA

Molecular weight: Translated: 22328; Mature: 22197

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPIDFYFDFSSPYGYLMSEKIDAVAAKHGRKVRWHPVLLGVIFQATGSRPPADGVSSK
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCC
STYMFHDFHRSARHMGIPYNPPSRFPLPTQNAARAYYWLHGQDCALARQFAHAVYRGFFV
CEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
DDLDVSSPDTVLDIAAKLGIDRAQLATALQAPEIKARLKDECDKALAAGVFGSPHVIIDG
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEECC
EAFFGADRLPQIEHWLETGGF
CHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SEPIDFYFDFSSPYGYLMSEKIDAVAAKHGRKVRWHPVLLGVIFQATGSRPPADGVSSK
CCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCC
STYMFHDFHRSARHMGIPYNPPSRFPLPTQNAARAYYWLHGQDCALARQFAHAVYRGFFV
CEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
DDLDVSSPDTVLDIAAKLGIDRAQLATALQAPEIKARLKDECDKALAAGVFGSPHVIIDG
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEECC
EAFFGADRLPQIEHWLETGGF
CHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002605; 1447127 [H]