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The map label for this gene is nagB [H]

Identifier: 71893925

GI number: 71893925

Start: 744532

End: 745296

Strand: Reverse

Name: nagB [H]

Synonym: MHJ_0576

Alternate gene names: 71893925

Gene position: 745296-744532 (Counterclockwise)

Preceding gene: 71893929

Following gene: 71893924

Centisome position: 83.05

GC content: 30.07

Gene sequence:

>765_bases
ATGAAGATATTAATTTTTGAAAAATTAAGCGATTTGCACAAATATTGTGCAAATCTTTTTATCGACCAAATTAGAACAAA
GCCAGATTCAGTCCTAGGTTTTGCAACCGGAATCTCGCCAGTTGAGACTTATAAACTTTTAGTAAAAGATCGCAAAGAGA
ACGGGACTTCTTGGGAAAAAATTACAACTTTTAACCTTGATGAATTTGTCGGAATTGACAAAAATCATTCAGAAGCTTTT
ATAAAACAGATGAAAACCAATTTATTTGACTTTGTCAATATTCCAACTTCACAAATAAATATTCCAGATTCTAAAGCTCT
AAATCCTGAAAAAGAAGCTAGACTTTATGAGGAAAAAATAGCGAAAAAACCAATTGATTTGCAATATATAAGCATTGGAA
TTAACGGTCATATGGCCTATAACGAACCTAAAACTCCATTTAATTCTAAAACACATGTGACAAATTTAACCCCTGAAACA
ATTGAGGATATGGTTAGAAAAGGTAAATTTTCCAGTTTTGATCAATGTCCTAAACAAGCAATTACAATGGGAATTCAAAC
AATTTTAAAATATACAAAAAAAGCTATTATGATCTCTTTTGGCTCTCATAAGGCCGATGTGACAAAATCAATGTTAGAAG
ATGAGCCTAATACAGAAATTAGTGCTTCTTTTTTACAATTACATCCAAATTGCACTTTCATTTTAGATAAAAAGGCAGCA
TCAAAATTATCAGAAAAAACTTTAAAAAGTGCAATTTGGTATTAA

Upstream 100 bases:

>100_bases
AAAATTGCAATATAAAAAAATTTTTTCGCTTTTTTTACTATTTTTTATTTTATGCGTGATAAAATTTCAATTATTACTAT
TTTAGATTAAAAAGGACAAA

Downstream 100 bases:

>100_bases
AAAATTTAGAAAAACTAGTTATAATGTCAGTAGGATTTGTAAAAAAAATAAAGTTTTTTCGGCCAAAAAAGGCCGAAAAT
TATAGTCAAAATTCGATTTT

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKILIFEKLSDLHKYCANLFIDQIRTKPDSVLGFATGISPVETYKLLVKDRKENGTSWEKITTFNLDEFVGIDKNHSEAF
IKQMKTNLFDFVNIPTSQINIPDSKALNPEKEARLYEEKIAKKPIDLQYISIGINGHMAYNEPKTPFNSKTHVTNLTPET
IEDMVRKGKFSSFDQCPKQAITMGIQTILKYTKKAIMISFGSHKADVTKSMLEDEPNTEISASFLQLHPNCTFILDKKAA
SKLSEKTLKSAIWY

Sequences:

>Translated_254_residues
MKILIFEKLSDLHKYCANLFIDQIRTKPDSVLGFATGISPVETYKLLVKDRKENGTSWEKITTFNLDEFVGIDKNHSEAF
IKQMKTNLFDFVNIPTSQINIPDSKALNPEKEARLYEEKIAKKPIDLQYISIGINGHMAYNEPKTPFNSKTHVTNLTPET
IEDMVRKGKFSSFDQCPKQAITMGIQTILKYTKKAIMISFGSHKADVTKSMLEDEPNTEISASFLQLHPNCTFILDKKAA
SKLSEKTLKSAIWY
>Mature_254_residues
MKILIFEKLSDLHKYCANLFIDQIRTKPDSVLGFATGISPVETYKLLVKDRKENGTSWEKITTFNLDEFVGIDKNHSEAF
IKQMKTNLFDFVNIPTSQINIPDSKALNPEKEARLYEEKIAKKPIDLQYISIGINGHMAYNEPKTPFNSKTHVTNLTPET
IEDMVRKGKFSSFDQCPKQAITMGIQTILKYTKKAIMISFGSHKADVTKSMLEDEPNTEISASFLQLHPNCTFILDKKAA
SKLSEKTLKSAIWY

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=257, Percent_Identity=31.9066147859922, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI19923881, Length=257, Percent_Identity=30.7392996108949, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1786893, Length=257, Percent_Identity=33.852140077821, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1789530, Length=228, Percent_Identity=27.6315789473684, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994958, Length=238, Percent_Identity=26.4705882352941, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554876, Length=256, Percent_Identity=33.59375, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24581960, Length=255, Percent_Identity=30.9803921568627, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI19920764, Length=255, Percent_Identity=30.9803921568627, Blast_Score=127, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 28907; Mature: 28907

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIFEKLSDLHKYCANLFIDQIRTKPDSVLGFATGISPVETYKLLVKDRKENGTSWEK
CEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCE
ITTFNLDEFVGIDKNHSEAFIKQMKTNLFDFVNIPTSQINIPDSKALNPEKEARLYEEKI
EEEECHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHH
AKKPIDLQYISIGINGHMAYNEPKTPFNSKTHVTNLTPETIEDMVRKGKFSSFDQCPKQA
HCCCCCEEEEEEEECCEEECCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHH
ITMGIQTILKYTKKAIMISFGSHKADVTKSMLEDEPNTEISASFLQLHPNCTFILDKKAA
HHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCCHHHHHEEECCCEEEEECCHHH
SKLSEKTLKSAIWY
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKILIFEKLSDLHKYCANLFIDQIRTKPDSVLGFATGISPVETYKLLVKDRKENGTSWEK
CEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCE
ITTFNLDEFVGIDKNHSEAFIKQMKTNLFDFVNIPTSQINIPDSKALNPEKEARLYEEKI
EEEECHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHH
AKKPIDLQYISIGINGHMAYNEPKTPFNSKTHVTNLTPETIEDMVRKGKFSSFDQCPKQA
HCCCCCEEEEEEEECCEEECCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHH
ITMGIQTILKYTKKAIMISFGSHKADVTKSMLEDEPNTEISASFLQLHPNCTFILDKKAA
HHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCCHHHHHEEECCCEEEEECCHHH
SKLSEKTLKSAIWY
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11353084 [H]