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The map label for this gene is lpxB

Identifier: 71892066

GI number: 71892066

Start: 338291

End: 339454

Strand: Direct

Name: lpxB

Synonym: BPEN_292

Alternate gene names: 71892066

Gene position: 338291-339454 (Clockwise)

Preceding gene: 71892065

Following gene: 71892067

Centisome position: 42.73

GC content: 31.53

Gene sequence:

>1164_bases
ATGTCATCTATCGTCCCGTCCATGCATAATAATCGCACTATTATTATAGGTATAGTAGCAGGAGAAGCTTCTGGAGATAT
TTTAGGAGCAGGACTAATCCGTACATTAAAAAAATACTTAAAAAAAGTACGTTTTTTTGGTATTGGCGGTCCCTGTATGC
AATCTGAAGATATGAAATCTTGGTATAATATAGAAGAATTATCAGTTATGGGTTTTGCTGAAATCGTTATGAAATTACCA
CGACTATTATATATTCGTAGAAATTTAGCTCGTAGATTTATTAACTTAAAACCTGATGTTTTCATTGGTATCGATTCTCC
AGATTTTAATATTTCGTTAGAAAATCGTTTGAAAAAACGTGGAATTCGTACAATTCATTATGTTAGCCCATCAGTATGGG
CATGGAGGAAAAAACGTATTTTTGCGCTTAAAAAAGCTACCGATAATATTTTGGTTATTTTGCCTTTTGAAAAAAAAATA
TACGATCACTTCAATATACCATGTCAATTTATTGGGCATTCATTAGCAGATCAAATACCACTTAATCCAAATAAAGTTTC
TGCTCGTCAAAAATTAGGTATTCCTCATGACGTATATTGTTTAGCAGTATTACCAGGCAGCAGAATTAGGGAAATTAAAA
TGTTAGCTCATGATTTTTTAGTATGCGCTAAATTATTAAAAAATAATTTTCCTAATCTTGAAATTTTAGTGCCATTAACT
AATCAGACATCTATAAAAAAATTTATTAGTGTTGCATCAACATCGGTTAAATATCGTGTTCTAAGCAACCAATCAGCATG
GGAGATAATGATGGCAGCAGATGCTTCTTTAGTAACCGCTGGAACAGCAACTTTAGAATGTATGTTGGTCAAATGCCCCA
TGGTTGTAGCTTATCGCATGCATCCCTTAACATTCATGTTAGCCAAGCATTTTATAAATATTCCCTGGATATCACTACCT
AATTTATTAGCAGGTCATGAATTGGTAAAAGAATTTATTCAAAATAACTGTCGTCCTGAAAATTTAGCACAGACATTAAT
TAATTTATTAAATAATAATAATCAACATATAGTATTGAAAAAAAAATTTAGACAATTACATCACAGCATTAGATGTAATG
CAGATGAACAAGCAGCCTATGCGGTTTTGAGATTAATCAAATGA

Upstream 100 bases:

>100_bases
CAGCTAAAGAGGCTTTAAAAGCCTTAGCAGCAGAACATCCAATTATCAATGAATTTGTAGATTTTTTAATACGCTCTCAA
CGAGGAATTATTCGTTAACA

Downstream 100 bases:

>100_bases
CAACAATGTTATCTATTGTGCAAGTAAAAAATAATGAAATACCAAAAACACTATCTATCAAAAAATTTAAATTAATTGCA
GGAGTAGATGAATCAGGATG

Product: lipid-A-disaccharide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSSIVPSMHNNRTIIIGIVAGEASGDILGAGLIRTLKKYLKKVRFFGIGGPCMQSEDMKSWYNIEELSVMGFAEIVMKLP
RLLYIRRNLARRFINLKPDVFIGIDSPDFNISLENRLKKRGIRTIHYVSPSVWAWRKKRIFALKKATDNILVILPFEKKI
YDHFNIPCQFIGHSLADQIPLNPNKVSARQKLGIPHDVYCLAVLPGSRIREIKMLAHDFLVCAKLLKNNFPNLEILVPLT
NQTSIKKFISVASTSVKYRVLSNQSAWEIMMAADASLVTAGTATLECMLVKCPMVVAYRMHPLTFMLAKHFINIPWISLP
NLLAGHELVKEFIQNNCRPENLAQTLINLLNNNNQHIVLKKKFRQLHHSIRCNADEQAAYAVLRLIK

Sequences:

>Translated_387_residues
MSSIVPSMHNNRTIIIGIVAGEASGDILGAGLIRTLKKYLKKVRFFGIGGPCMQSEDMKSWYNIEELSVMGFAEIVMKLP
RLLYIRRNLARRFINLKPDVFIGIDSPDFNISLENRLKKRGIRTIHYVSPSVWAWRKKRIFALKKATDNILVILPFEKKI
YDHFNIPCQFIGHSLADQIPLNPNKVSARQKLGIPHDVYCLAVLPGSRIREIKMLAHDFLVCAKLLKNNFPNLEILVPLT
NQTSIKKFISVASTSVKYRVLSNQSAWEIMMAADASLVTAGTATLECMLVKCPMVVAYRMHPLTFMLAKHFINIPWISLP
NLLAGHELVKEFIQNNCRPENLAQTLINLLNNNNQHIVLKKKFRQLHHSIRCNADEQAAYAVLRLIK
>Mature_386_residues
SSIVPSMHNNRTIIIGIVAGEASGDILGAGLIRTLKKYLKKVRFFGIGGPCMQSEDMKSWYNIEELSVMGFAEIVMKLPR
LLYIRRNLARRFINLKPDVFIGIDSPDFNISLENRLKKRGIRTIHYVSPSVWAWRKKRIFALKKATDNILVILPFEKKIY
DHFNIPCQFIGHSLADQIPLNPNKVSARQKLGIPHDVYCLAVLPGSRIREIKMLAHDFLVCAKLLKNNFPNLEILVPLTN
QTSIKKFISVASTSVKYRVLSNQSAWEIMMAADASLVTAGTATLECMLVKCPMVVAYRMHPLTFMLAKHFINIPWISLPN
LLAGHELVKEFIQNNCRPENLAQTLINLLNNNNQHIVLKKKFRQLHHSIRCNADEQAAYAVLRLIK

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell

COG id: COG0763

COG function: function code M; Lipid A disaccharide synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxB family

Homologues:

Organism=Escherichia coli, GI1786379, Length=382, Percent_Identity=55.7591623036649, Blast_Score=449, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXB_BLOPB (Q493B9)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277796.1
- ProteinModelPortal:   Q493B9
- STRING:   Q493B9
- GeneID:   3562929
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_292
- eggNOG:   COG0763
- HOGENOM:   HBG584837
- OMA:   DFTHRVA
- ProtClustDB:   CLSK280787
- BioCyc:   CBLO291272:BPEN_292-MONOMER
- HAMAP:   MF_00392
- InterPro:   IPR003835
- TIGRFAMs:   TIGR00215

Pfam domain/function: PF02684 LpxB

EC number: =2.4.1.182

Molecular weight: Translated: 44035; Mature: 43904

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIVPSMHNNRTIIIGIVAGEASGDILGAGLIRTLKKYLKKVRFFGIGGPCMQSEDMKS
CCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHH
WYNIEELSVMGFAEIVMKLPRLLYIRRNLARRFINLKPDVFIGIDSPDFNISLENRLKKR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEHHHHHHHC
GIRTIHYVSPSVWAWRKKRIFALKKATDNILVILPFEKKIYDHFNIPCQFIGHSLADQIP
CCCEEEEECCCHHHHHHHHEEEEEECCCCEEEEEECHHHHHHCCCCCHHHHCCHHHHCCC
LNPNKVSARQKLGIPHDVYCLAVLPGSRIREIKMLAHDFLVCAKLLKNNFPNLEILVPLT
CCCCHHCHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
NQTSIKKFISVASTSVKYRVLSNQSAWEIMMAADASLVTAGTATLECMLVKCPMVVAYRM
CCHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCEEECCCHHEEHHHHHCHHHHHHHH
HPLTFMLAKHFINIPWISLPNLLAGHELVKEFIQNNCRPENLAQTLINLLNNNNQHIVLK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEH
KKFRQLHHSIRCNADEQAAYAVLRLIK
HHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SSIVPSMHNNRTIIIGIVAGEASGDILGAGLIRTLKKYLKKVRFFGIGGPCMQSEDMKS
CCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHH
WYNIEELSVMGFAEIVMKLPRLLYIRRNLARRFINLKPDVFIGIDSPDFNISLENRLKKR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEHHHHHHHC
GIRTIHYVSPSVWAWRKKRIFALKKATDNILVILPFEKKIYDHFNIPCQFIGHSLADQIP
CCCEEEEECCCHHHHHHHHEEEEEECCCCEEEEEECHHHHHHCCCCCHHHHCCHHHHCCC
LNPNKVSARQKLGIPHDVYCLAVLPGSRIREIKMLAHDFLVCAKLLKNNFPNLEILVPLT
CCCCHHCHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
NQTSIKKFISVASTSVKYRVLSNQSAWEIMMAADASLVTAGTATLECMLVKCPMVVAYRM
CCHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCEEECCCHHEEHHHHHCHHHHHHHH
HPLTFMLAKHFINIPWISLPNLLAGHELVKEFIQNNCRPENLAQTLINLLNNNNQHIVLK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEH
KKFRQLHHSIRCNADEQAAYAVLRLIK
HHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA