Click here to switch to the map view.

The map label for this gene is cysH [H]

Identifier: 71891948

GI number: 71891948

Start: 212284

End: 213045

Strand: Direct

Name: cysH [H]

Synonym: BPEN_165

Alternate gene names: 71891948

Gene position: 212284-213045 (Clockwise)

Preceding gene: 71891947

Following gene: 71891949

Centisome position: 26.82

GC content: 31.76

Gene sequence:

>762_bases
ATGAATAAACTATTAAATGTTATTAATCATTGCTGGACTGTTACAGAATTCAATTCATTAGACATTAATGAACAAAAATT
GGTTTTAGTTAAAATAAATCGATATTTGGAATCTTTAAATACGGTAGATAGGTTCAAATGGGCTATAGAATATTTACCTA
AGCAAGCAATATTGTCTTCGAGTTTTGGTATTCAATCATCAGTCAGTTTACATTTAACCACTCATTATTATCCTAACATT
CCGATTATTTTAATTGATACTGGTTATTTATTTCCAGAAACATATCGATTTATTGATCGATTGACAGAAAAAATGCAATT
AAATTTACATATATTTTCTCCGAATCAATCTGCAGCATGGCAAGAAGCACGATATGGTAAATTATGGACACAGGGTATAA
AAGGGATCCAAAAATACAATGCTATTAACAAAGTTGAACCCATGCATCGTGCTCTAAGAACGCTGAAAGTGGAAACATGG
TTTGCAGGCTTAAGAAGAAATCAGTCAGATAGCCGTAAAAAATTGCCAATCATAACCATTCAAAATGGAATTTTTAAATT
CTTACCTATCGTTGATTGGAATTCTCTTCAGATTCATAGGTACATTGAAAAACATTCTTTGGAATATCATCCATTGTGGC
AACAAGGTTATGTATCAATAGGAGATGTGCATACTAGCAGAAAATGGGAACCTGGTATGAAAGAAGAAGACACACGTTTT
TTTGGGTTACAACGTGAATGTGGTTTACATATTATTGAGTGA

Upstream 100 bases:

>100_bases
AGTCGTTGGGCACAAGAGAGAAATAGTCAAGAATCTTATGGAGATTATGTAGTAAGATCTGGGATAGTTAATGCTGTTAT
AAATTCTGAAAAAGATTTTT

Downstream 100 bases:

>100_bases
ATTCATTATTTATATGAAATATTTATGTGATAATACTTTATTTGCATTAGTACAGTATCCTGTACTTCAGGACAGTATCC
TGATTGATAGCATGTATTCT

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNKLLNVINHCWTVTEFNSLDINEQKLVLVKINRYLESLNTVDRFKWAIEYLPKQAILSSSFGIQSSVSLHLTTHYYPNI
PIILIDTGYLFPETYRFIDRLTEKMQLNLHIFSPNQSAAWQEARYGKLWTQGIKGIQKYNAINKVEPMHRALRTLKVETW
FAGLRRNQSDSRKKLPIITIQNGIFKFLPIVDWNSLQIHRYIEKHSLEYHPLWQQGYVSIGDVHTSRKWEPGMKEEDTRF
FGLQRECGLHIIE

Sequences:

>Translated_253_residues
MNKLLNVINHCWTVTEFNSLDINEQKLVLVKINRYLESLNTVDRFKWAIEYLPKQAILSSSFGIQSSVSLHLTTHYYPNI
PIILIDTGYLFPETYRFIDRLTEKMQLNLHIFSPNQSAAWQEARYGKLWTQGIKGIQKYNAINKVEPMHRALRTLKVETW
FAGLRRNQSDSRKKLPIITIQNGIFKFLPIVDWNSLQIHRYIEKHSLEYHPLWQQGYVSIGDVHTSRKWEPGMKEEDTRF
FGLQRECGLHIIE
>Mature_253_residues
MNKLLNVINHCWTVTEFNSLDINEQKLVLVKINRYLESLNTVDRFKWAIEYLPKQAILSSSFGIQSSVSLHLTTHYYPNI
PIILIDTGYLFPETYRFIDRLTEKMQLNLHIFSPNQSAAWQEARYGKLWTQGIKGIQKYNAINKVEPMHRALRTLKVETW
FAGLRRNQSDSRKKLPIITIQNGIFKFLPIVDWNSLQIHRYIEKHSLEYHPLWQQGYVSIGDVHTSRKWEPGMKEEDTRF
FGLQRECGLHIIE

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=234, Percent_Identity=61.5384615384615, Blast_Score=328, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6325425, Length=219, Percent_Identity=31.5068493150685, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 29890; Mature: 29890

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLLNVINHCWTVTEFNSLDINEQKLVLVKINRYLESLNTVDRFKWAIEYLPKQAILSS
CHHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
SFGIQSSVSLHLTTHYYPNIPIILIDTGYLFPETYRFIDRLTEKMQLNLHIFSPNQSAAW
CCCCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCHH
QEARYGKLWTQGIKGIQKYNAINKVEPMHRALRTLKVETWFAGLRRNQSDSRKKLPIITI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
QNGIFKFLPIVDWNSLQIHRYIEKHSLEYHPLWQQGYVSIGDVHTSRKWEPGMKEEDTRF
CCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHCCCEEEECCCCCCCCCCCCCCCCCCE
FGLQRECGLHIIE
ECCHHHCCCEECC
>Mature Secondary Structure
MNKLLNVINHCWTVTEFNSLDINEQKLVLVKINRYLESLNTVDRFKWAIEYLPKQAILSS
CHHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
SFGIQSSVSLHLTTHYYPNIPIILIDTGYLFPETYRFIDRLTEKMQLNLHIFSPNQSAAW
CCCCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCHH
QEARYGKLWTQGIKGIQKYNAINKVEPMHRALRTLKVETWFAGLRRNQSDSRKKLPIITI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
QNGIFKFLPIVDWNSLQIHRYIEKHSLEYHPLWQQGYVSIGDVHTSRKWEPGMKEEDTRF
CCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHCCCEEEECCCCCCCCCCCCCCCCCCE
FGLQRECGLHIIE
ECCHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA