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The map label for this gene is cysJ [H]

Identifier: 71891946

GI number: 71891946

Start: 208744

End: 210564

Strand: Direct

Name: cysJ [H]

Synonym: BPEN_163

Alternate gene names: 71891946

Gene position: 208744-210564 (Clockwise)

Preceding gene: 71891945

Following gene: 71891947

Centisome position: 26.37

GC content: 31.8

Gene sequence:

>1821_bases
ATGATAAAAAAAACAGCACATAGCGAAATAACACCGTTAACTTCAGAACAGTTAGATTATATTCGATCATTTTTAGTTAC
TTTGTCCAGTTCTCAACTGATTTGGATATCCGGATACTTATGGGGATTAGCAAGTGTTGCAGAAACTAATAAAATAACTG
ATATTTCTGAAAACACTAAAATAGAAGGTGTTTGTCTTAATAAAACAATTACTTTAATATCTGCTTCTCAAACTGGAAAT
GCACGTCAATTAGCTGAGAAGTTACGTGATGATATTCGTGCAATTAATATGGATGTCATGTTGTTTGATGCTAGAGATTA
CAAATTTAAGAAAATTTCTAAAGAAAGATTATTAATTATTATTACTTCCACTTATGGAGAGGGAGAACCTCCAGAAGAAG
CAATTGCGTTATACAGGTATTTATTTTCCAATAAAGCAGTTAAAATGCCAAATACTCATTTTGCGGTATTCAGTTTTGGA
GATCGGTCATATGAATATTTTGCTAAAGCTGGAAAAGATTTTGATCATCGATTAGAGGAGCTTGGAGCGCATCGATTATG
CGATCGAGTCGACGTCGATATCGATTTTAAAGAAGAAGCTAATGTATGGAGAAAAAAGATAGTTCTTTTATTAAAAAATA
AAATAATATCTACTTCTACATTTAAGCAAAATAATAACAGTTGTAGTCTTGAACAAGTAAATAACACTGTATATAACAAA
GAATGTCCATTAATTGCTTGTTTATCAACCCGATACAAAATTACTAGTCGTGATTCACTGAAAGATGTGCATCATTTAGA
GATAGATATTGCTGATTCTGATTTACACTATCAACCAGGAGATGCGTTAGGAGTGTGGTATGAAAATGATCCTAATCTTA
TTAATGAGTTACTAGAATTATTAAGATTGAAAGGAACTGAACAAGTACGAGTTAAAGAAGAGCCAATGTCTCTTAGTGAA
GCATTACAGAAACATTATGAATTAACTCATAATACTTCCGTTGTTGTAAAAAATATAGCTACTATTACTCAAGATAAAAT
GTTGTTGGATTTACTCTGCAATTCAGAAAAATTAAATAAATTTATTTTAACTACGCCTATTATTGCAATGATGCATCGTG
TATCAATTGCAATAACTCCGCAAGAGTTATTGCAAATATTACGTCCTATGAAACCCCGATTTTATTCCATTTCTTCCGCT
CAATCAGAGGTAGGAGATGAAATACATATTACTGTAAGCGTAGTACGTTATAAGACAAATGAACGCTTTAGAACAGGTGG
TGCTAGTGGTTATTTAGTAGATCGCATAAAAGAAAATGAAAAAATACGTATTTTTATTGAACCTAATAATAATTTTAGAC
TACCAAAAAATTCTAATGTTCCAGTAATTATGATTGGGGCCGGAACAGGTATTGCTCCGTTTCGTGCTTTTATGCAACAA
AGATCTGCAGATAGTGCATCAGGAAAAAACTGGTTATTTTTTGGGAATTTAAGATTTATAGATGATTTTCTTTATCAAAT
TGAATGGCAACGTTATTTCAGAGATGGTTTATTAACCAAAATTGATACAGCTTGGTCCAGAGATCAAAATGATAAGATTT
ATGTACAAAACAAATTATTAAAGAATGGCGTAGAGCTTTGGTCATGGATTCAAGAAGGAGCTCATATTTATGTATGTGGC
GATGCTAAACATATGGCTCAAGATGTAAATAAGGCTTTAGTTATGTTAGCATCTAAATACGGGAGTATGGGTTTAGATAA
AGCGAATGAATTTTGGCATAACATGCGGATACAACATCGTTATCAGAGAGATATTTACTAA

Upstream 100 bases:

>100_bases
AAATTGGGTTACGTGGACATATCAATATTTTAAGAAGATGCACATCCTTACTAATTTGTAAGATTTGTTATTTATGCAAC
AGATTAAGTAGTTTAATTTA

Downstream 100 bases:

>100_bases
TGAACAGAAAATATGATAATAACAATGATAAAAATATACCCTTATTATCCGATAATGAGCGAATCAAAAAAGAAAGCAAC
TTCCTAAGAGGTACTATTGC

Product: sulfite reductase, alpha subunit (flavoprotein)

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MIKKTAHSEITPLTSEQLDYIRSFLVTLSSSQLIWISGYLWGLASVAETNKITDISENTKIEGVCLNKTITLISASQTGN
ARQLAEKLRDDIRAINMDVMLFDARDYKFKKISKERLLIIITSTYGEGEPPEEAIALYRYLFSNKAVKMPNTHFAVFSFG
DRSYEYFAKAGKDFDHRLEELGAHRLCDRVDVDIDFKEEANVWRKKIVLLLKNKIISTSTFKQNNNSCSLEQVNNTVYNK
ECPLIACLSTRYKITSRDSLKDVHHLEIDIADSDLHYQPGDALGVWYENDPNLINELLELLRLKGTEQVRVKEEPMSLSE
ALQKHYELTHNTSVVVKNIATITQDKMLLDLLCNSEKLNKFILTTPIIAMMHRVSIAITPQELLQILRPMKPRFYSISSA
QSEVGDEIHITVSVVRYKTNERFRTGGASGYLVDRIKENEKIRIFIEPNNNFRLPKNSNVPVIMIGAGTGIAPFRAFMQQ
RSADSASGKNWLFFGNLRFIDDFLYQIEWQRYFRDGLLTKIDTAWSRDQNDKIYVQNKLLKNGVELWSWIQEGAHIYVCG
DAKHMAQDVNKALVMLASKYGSMGLDKANEFWHNMRIQHRYQRDIY

Sequences:

>Translated_606_residues
MIKKTAHSEITPLTSEQLDYIRSFLVTLSSSQLIWISGYLWGLASVAETNKITDISENTKIEGVCLNKTITLISASQTGN
ARQLAEKLRDDIRAINMDVMLFDARDYKFKKISKERLLIIITSTYGEGEPPEEAIALYRYLFSNKAVKMPNTHFAVFSFG
DRSYEYFAKAGKDFDHRLEELGAHRLCDRVDVDIDFKEEANVWRKKIVLLLKNKIISTSTFKQNNNSCSLEQVNNTVYNK
ECPLIACLSTRYKITSRDSLKDVHHLEIDIADSDLHYQPGDALGVWYENDPNLINELLELLRLKGTEQVRVKEEPMSLSE
ALQKHYELTHNTSVVVKNIATITQDKMLLDLLCNSEKLNKFILTTPIIAMMHRVSIAITPQELLQILRPMKPRFYSISSA
QSEVGDEIHITVSVVRYKTNERFRTGGASGYLVDRIKENEKIRIFIEPNNNFRLPKNSNVPVIMIGAGTGIAPFRAFMQQ
RSADSASGKNWLFFGNLRFIDDFLYQIEWQRYFRDGLLTKIDTAWSRDQNDKIYVQNKLLKNGVELWSWIQEGAHIYVCG
DAKHMAQDVNKALVMLASKYGSMGLDKANEFWHNMRIQHRYQRDIY
>Mature_606_residues
MIKKTAHSEITPLTSEQLDYIRSFLVTLSSSQLIWISGYLWGLASVAETNKITDISENTKIEGVCLNKTITLISASQTGN
ARQLAEKLRDDIRAINMDVMLFDARDYKFKKISKERLLIIITSTYGEGEPPEEAIALYRYLFSNKAVKMPNTHFAVFSFG
DRSYEYFAKAGKDFDHRLEELGAHRLCDRVDVDIDFKEEANVWRKKIVLLLKNKIISTSTFKQNNNSCSLEQVNNTVYNK
ECPLIACLSTRYKITSRDSLKDVHHLEIDIADSDLHYQPGDALGVWYENDPNLINELLELLRLKGTEQVRVKEEPMSLSE
ALQKHYELTHNTSVVVKNIATITQDKMLLDLLCNSEKLNKFILTTPIIAMMHRVSIAITPQELLQILRPMKPRFYSISSA
QSEVGDEIHITVSVVRYKTNERFRTGGASGYLVDRIKENEKIRIFIEPNNNFRLPKNSNVPVIMIGAGTGIAPFRAFMQQ
RSADSASGKNWLFFGNLRFIDDFLYQIEWQRYFRDGLLTKIDTAWSRDQNDKIYVQNKLLKNGVELWSWIQEGAHIYVCG
DAKHMAQDVNKALVMLASKYGSMGLDKANEFWHNMRIQHRYQRDIY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=603, Percent_Identity=28.0265339966833, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI24041029, Length=596, Percent_Identity=29.0268456375839, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI10835173, Length=675, Percent_Identity=28.1481481481481, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI7657393, Length=600, Percent_Identity=25.1666666666667, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI221316709, Length=600, Percent_Identity=25.1666666666667, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI221316705, Length=609, Percent_Identity=24.7947454844007, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI40254422, Length=673, Percent_Identity=26.4487369985141, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI221316707, Length=526, Percent_Identity=26.0456273764259, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI169790956, Length=422, Percent_Identity=27.0142180094787, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI169790958, Length=422, Percent_Identity=27.2511848341232, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1789123, Length=606, Percent_Identity=51.980198019802, Blast_Score=684, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17554134, Length=595, Percent_Identity=26.5546218487395, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17566446, Length=572, Percent_Identity=24.3006993006993, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17531441, Length=397, Percent_Identity=23.1738035264484, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321832, Length=642, Percent_Identity=27.5700934579439, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6321143, Length=389, Percent_Identity=28.2776349614396, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6325305, Length=632, Percent_Identity=23.7341772151899, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17137192, Length=617, Percent_Identity=26.418152350081, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24582192, Length=518, Percent_Identity=27.2200772200772, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24660907, Length=593, Percent_Identity=24.7892074198988, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24660903, Length=593, Percent_Identity=24.7892074198988, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24583543, Length=530, Percent_Identity=28.6792452830189, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI78706876, Length=530, Percent_Identity=28.6792452830189, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI78706872, Length=530, Percent_Identity=28.6792452830189, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 69761; Mature: 69761

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKTAHSEITPLTSEQLDYIRSFLVTLSSSQLIWISGYLWGLASVAETNKITDISENTK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCE
IEGVCLNKTITLISASQTGNARQLAEKLRDDIRAINMDVMLFDARDYKFKKISKERLLII
EEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHEEEEEEEEEECCCCHHHCCCCCEEEEE
ITSTYGEGEPPEEAIALYRYLFSNKAVKMPNTHFAVFSFGDRSYEYFAKAGKDFDHRLEE
EEECCCCCCCHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCHHHHHHCCCCHHHHHHH
LGAHRLCDRVDVDIDFKEEANVWRKKIVLLLKNKIISTSTFKQNNNSCSLEQVNNTVYNK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHCCCEECC
ECPLIACLSTRYKITSRDSLKDVHHLEIDIADSDLHYQPGDALGVWYENDPNLINELLEL
CCCEEEEECCCEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHH
LRLKGTEQVRVKEEPMSLSEALQKHYELTHNTSVVVKNIATITQDKMLLDLLCNSEKLNK
HHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCH
FILTTPIIAMMHRVSIAITPQELLQILRPMKPRFYSISSAQSEVGDEIHITVSVVRYKTN
HHHHHHHHHHHHHHEEEECHHHHHHHHCCCCCCEEECCCHHHHCCCEEEEEEEEEEEECC
ERFRTGGASGYLVDRIKENEKIRIFIEPNNNFRLPKNSNVPVIMIGAGTGIAPFRAFMQQ
CCEECCCCCCEEEHHCCCCCEEEEEEECCCCEECCCCCCCCEEEEECCCCHHHHHHHHHH
RSADSASGKNWLFFGNLRFIDDFLYQIEWQRYFRDGLLTKIDTAWSRDQNDKIYVQNKLL
HCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEHHHH
KNGVELWSWIQEGAHIYVCGDAKHMAQDVNKALVMLASKYGSMGLDKANEFWHNMRIQHR
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
YQRDIY
HHCCCC
>Mature Secondary Structure
MIKKTAHSEITPLTSEQLDYIRSFLVTLSSSQLIWISGYLWGLASVAETNKITDISENTK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCE
IEGVCLNKTITLISASQTGNARQLAEKLRDDIRAINMDVMLFDARDYKFKKISKERLLII
EEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHEEEEEEEEEECCCCHHHCCCCCEEEEE
ITSTYGEGEPPEEAIALYRYLFSNKAVKMPNTHFAVFSFGDRSYEYFAKAGKDFDHRLEE
EEECCCCCCCHHHHHHHHHHHHCCCCEECCCCEEEEEEECCCCHHHHHHCCCCHHHHHHH
LGAHRLCDRVDVDIDFKEEANVWRKKIVLLLKNKIISTSTFKQNNNSCSLEQVNNTVYNK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHCCCEECC
ECPLIACLSTRYKITSRDSLKDVHHLEIDIADSDLHYQPGDALGVWYENDPNLINELLEL
CCCEEEEECCCEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHH
LRLKGTEQVRVKEEPMSLSEALQKHYELTHNTSVVVKNIATITQDKMLLDLLCNSEKLNK
HHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCH
FILTTPIIAMMHRVSIAITPQELLQILRPMKPRFYSISSAQSEVGDEIHITVSVVRYKTN
HHHHHHHHHHHHHHEEEECHHHHHHHHCCCCCCEEECCCHHHHCCCEEEEEEEEEEEECC
ERFRTGGASGYLVDRIKENEKIRIFIEPNNNFRLPKNSNVPVIMIGAGTGIAPFRAFMQQ
CCEECCCCCCEEEHHCCCCCEEEEEEECCCCEECCCCCCCCEEEEECCCCHHHHHHHHHH
RSADSASGKNWLFFGNLRFIDDFLYQIEWQRYFRDGLLTKIDTAWSRDQNDKIYVQNKLL
HCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEHHHH
KNGVELWSWIQEGAHIYVCGDAKHMAQDVNKALVMLASKYGSMGLDKANEFWHNMRIQHR
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
YQRDIY
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12886019 [H]