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The map label for this gene is thrC [H]

Identifier: 71891900

GI number: 71891900

Start: 139712

End: 141013

Strand: Direct

Name: thrC [H]

Synonym: BPEN_117

Alternate gene names: 71891900

Gene position: 139712-141013 (Clockwise)

Preceding gene: 71891899

Following gene: 71891901

Centisome position: 17.65

GC content: 31.34

Gene sequence:

>1302_bases
ATGAAACTATATAATATTAAGCAACCTAGTGAACAAGTCACGTTTACTCAAGCTCTCTTACAAGGATTAGGAAAAAATCA
GGGGTTATTTTTCCCAAAAGATCTTCCAAAATTCTCTATATTTGAAATAAATTCTCTCTTAGAAATGAGTTTTATAGAAC
GTAGTACGCATATTTTGTCTACATATATTGGCTCTGAATTATCAAAAAATAGTATATTAACTTGTGTTAAAAATGCTTTT
AATTTTCCAGTCCCATTAGTGTGTATAAATAATAATGTTGCAATTTTAGAACTTTTTCATGGCCCAACTTTGGCTTTTAA
AGATTTTGGAAGCCGATTAATGGCGCAAATGTTAAATCAGACTAACCATTGTTCTGATAAACCAATGGTTATTCTGACTG
CTACTTCTGGAGATACAGGTGCTGCTGTAGCCCATGCTTTTTTTAATTTAAGCAATATACATGTTATAATTCTTTACCCT
AGAGGCAAGATTAGTGCATTACAAGAAAAATTATTTTGCACTTTAGGAGGCAATATTTCTACAATATCAGTAAATGGAGA
TTTTGATTCATGTCAACGTTTAGTTAAGAAAGCTTTTGATGACAGTGTACTGCGACAGAAATTAAATTTAAATTCTGCGA
ATTCCATTAACATTGGCCGATTATTAGCTCAAATTTGTTACTATTTTGAAGGGGTATCACAATTACCGCATCAAATGCGT
AATAAATTAGTTATTGCGGTTCCTAGCGGTAATTTTGGAAATTTAACAGCAGGACTATTAGCTCAATCTTGTGGATTACC
AGTAAAGAAGTTTATTGCTGCTACTAATATTAATGATACTGTGCCTAGATTTTTAGAGTTTGGTTATTGGGAACCTCGCC
CTACTCTTTCAACGTTTTCTAATGCTATGGATGTAAGCTCTCCAAATAATTGGTCTAGAATAGAAGAATTGTTTCGTCGA
GAAAATAAATCTATTAAAGAATTGGAATATGGTTGTGTTAATGATTTTCTCACCGAGAAAACAGTCCAAGAAATTGCAGA
TTTGGGATATCTTTCCGAACCTCATACCGCTGTAGCATATCGATTACTGTGTGATAAATTACATTCTGATGAATTTGGTA
TATGTCTTGGTACTGCTCATCCTGTTAAATTTAAAGAGTTAGTAGAGGATTTTTTAAAAAAAAAGATACAATTAATATTA
CCAATTGTATTAAAAGAACGTATGAAATTACCTGTTTTATCGTTTAAAATACCTAAATGTTTCTCTTCATTACGTAACCT
AATTTTAAGCATAATGTCTTAA

Upstream 100 bases:

>100_bases
TTTCTGATTGGTTATCACGTTTTTATTTACAAAATAATTCAGGTTTTATTCGAATCTGTTCTTTAGATAATCTTGGAGCG
CGTATTATGGTGAATAATTA

Downstream 100 bases:

>100_bases
AATATTATGCATATCATATACTACAAACATATATGTGTTATATTAAAATCTAGTATTTTTTATATTTTGCGTTCGTTAAT
GCATTTAATAAGATTATAAA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MKLYNIKQPSEQVTFTQALLQGLGKNQGLFFPKDLPKFSIFEINSLLEMSFIERSTHILSTYIGSELSKNSILTCVKNAF
NFPVPLVCINNNVAILELFHGPTLAFKDFGSRLMAQMLNQTNHCSDKPMVILTATSGDTGAAVAHAFFNLSNIHVIILYP
RGKISALQEKLFCTLGGNISTISVNGDFDSCQRLVKKAFDDSVLRQKLNLNSANSINIGRLLAQICYYFEGVSQLPHQMR
NKLVIAVPSGNFGNLTAGLLAQSCGLPVKKFIAATNINDTVPRFLEFGYWEPRPTLSTFSNAMDVSSPNNWSRIEELFRR
ENKSIKELEYGCVNDFLTEKTVQEIADLGYLSEPHTAVAYRLLCDKLHSDEFGICLGTAHPVKFKELVEDFLKKKIQLIL
PIVLKERMKLPVLSFKIPKCFSSLRNLILSIMS

Sequences:

>Translated_433_residues
MKLYNIKQPSEQVTFTQALLQGLGKNQGLFFPKDLPKFSIFEINSLLEMSFIERSTHILSTYIGSELSKNSILTCVKNAF
NFPVPLVCINNNVAILELFHGPTLAFKDFGSRLMAQMLNQTNHCSDKPMVILTATSGDTGAAVAHAFFNLSNIHVIILYP
RGKISALQEKLFCTLGGNISTISVNGDFDSCQRLVKKAFDDSVLRQKLNLNSANSINIGRLLAQICYYFEGVSQLPHQMR
NKLVIAVPSGNFGNLTAGLLAQSCGLPVKKFIAATNINDTVPRFLEFGYWEPRPTLSTFSNAMDVSSPNNWSRIEELFRR
ENKSIKELEYGCVNDFLTEKTVQEIADLGYLSEPHTAVAYRLLCDKLHSDEFGICLGTAHPVKFKELVEDFLKKKIQLIL
PIVLKERMKLPVLSFKIPKCFSSLRNLILSIMS
>Mature_433_residues
MKLYNIKQPSEQVTFTQALLQGLGKNQGLFFPKDLPKFSIFEINSLLEMSFIERSTHILSTYIGSELSKNSILTCVKNAF
NFPVPLVCINNNVAILELFHGPTLAFKDFGSRLMAQMLNQTNHCSDKPMVILTATSGDTGAAVAHAFFNLSNIHVIILYP
RGKISALQEKLFCTLGGNISTISVNGDFDSCQRLVKKAFDDSVLRQKLNLNSANSINIGRLLAQICYYFEGVSQLPHQMR
NKLVIAVPSGNFGNLTAGLLAQSCGLPVKKFIAATNINDTVPRFLEFGYWEPRPTLSTFSNAMDVSSPNNWSRIEELFRR
ENKSIKELEYGCVNDFLTEKTVQEIADLGYLSEPHTAVAYRLLCDKLHSDEFGICLGTAHPVKFKELVEDFLKKKIQLIL
PIVLKERMKLPVLSFKIPKCFSSLRNLILSIMS

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Homo sapiens, GI153792148, Length=436, Percent_Identity=31.651376146789, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI149193323, Length=418, Percent_Identity=28.7081339712919, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI1786185, Length=430, Percent_Identity=62.5581395348837, Blast_Score=551, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6319901, Length=446, Percent_Identity=33.8565022421525, Blast_Score=206, Evalue=5e-54,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 48461; Mature: 48461

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYNIKQPSEQVTFTQALLQGLGKNQGLFFPKDLPKFSIFEINSLLEMSFIERSTHILS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TYIGSELSKNSILTCVKNAFNFPVPLVCINNNVAILELFHGPTLAFKDFGSRLMAQMLNQ
HHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
TNHCSDKPMVILTATSGDTGAAVAHAFFNLSNIHVIILYPRGKISALQEKLFCTLGGNIS
CCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHEECCCEE
TISVNGDFDSCQRLVKKAFDDSVLRQKLNLNSANSINIGRLLAQICYYFEGVSQLPHQMR
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NKLVIAVPSGNFGNLTAGLLAQSCGLPVKKFIAATNINDTVPRFLEFGYWEPRPTLSTFS
CCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHH
NAMDVSSPNNWSRIEELFRRENKSIKELEYGCVNDFLTEKTVQEIADLGYLSEPHTAVAY
HHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RLLCDKLHSDEFGICLGTAHPVKFKELVEDFLKKKIQLILPIVLKERMKLPVLSFKIPKC
HHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHH
FSSLRNLILSIMS
HHHHHHHHHHHCC
>Mature Secondary Structure
MKLYNIKQPSEQVTFTQALLQGLGKNQGLFFPKDLPKFSIFEINSLLEMSFIERSTHILS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TYIGSELSKNSILTCVKNAFNFPVPLVCINNNVAILELFHGPTLAFKDFGSRLMAQMLNQ
HHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
TNHCSDKPMVILTATSGDTGAAVAHAFFNLSNIHVIILYPRGKISALQEKLFCTLGGNIS
CCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHEECCCEE
TISVNGDFDSCQRLVKKAFDDSVLRQKLNLNSANSINIGRLLAQICYYFEGVSQLPHQMR
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NKLVIAVPSGNFGNLTAGLLAQSCGLPVKKFIAATNINDTVPRFLEFGYWEPRPTLSTFS
CCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHH
NAMDVSSPNNWSRIEELFRRENKSIKELEYGCVNDFLTEKTVQEIADLGYLSEPHTAVAY
HHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RLLCDKLHSDEFGICLGTAHPVKFKELVEDFLKKKIQLILPIVLKERMKLPVLSFKIPKC
HHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHH
FSSLRNLILSIMS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8423151 [H]