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The map label for this gene is degQ [H]

Identifier: 71891839

GI number: 71891839

Start: 58826

End: 60199

Strand: Reverse

Name: degQ [H]

Synonym: BPEN_048

Alternate gene names: 71891839

Gene position: 60199-58826 (Counterclockwise)

Preceding gene: 71891840

Following gene: 71891836

Centisome position: 7.6

GC content: 35.08

Gene sequence:

>1374_bases
ATGAAGATAACACATTTCCTAAAAATATTAAGTATATTATTCACATTGGGAATTTCATATGCTGAATCTTCTATAAATCA
CACAACATTTTCTACAGAAATATCGGGACTCTTACCGAGTTTAGCTCCCATGTTAGATACAGTACTGCCAGCAGTAGTAA
GTGTACATGTTGAAGGTATTCAACCTGCGAGAAGACTTACATTGCCTAAAGAATTTAAATATTTTTTTGGACCAGATATC
CCTGGAGGAAATTTTGGATCTAGACCATTCGAAGGACTAGGATCTGGAGTGATTATTAACGCTAATAAAGGCTACATTAT
TACCAATAACCATGTTGTCAATGGTGCAGATAAAATTAAAATACAACTTAACGATGGTCGCGAATTTGACGCTAAACTAG
TAGGACATGATGAACAAACTGACTTAGCATTACTTCAATTATTAAAATTTAAAAATCTCTCTGAAATAAAAATGGCTGAT
TCTGATATTTTGAAAGTTGGTGATTTTGCTGTTGCGATTGGCAACCCCTTTGGATTAGGTCAAACAGCAACTTCTGGTAT
TATATCAGCATTGGGAAGAAGTGGTTTAAACCTTGAAGGATTAGAAAATTTTATACAAACTGATGCCTCCATAAATAGAG
GAAATTCTGGAGGGGCACTAGTAAACTTACATGGAGAATTAATTGGAATTAATACTGCTATTTTAGCGCCTGGAGGAGGA
AATATTGGCATTGGTTTTGCTATTCCTAGCAACATTGTGAAAAATTTAAGCCAACAATTAATTGAATTTGGAGAAGTAAA
AAGAGGTCAATTAGGAATAAAAGGCACAGAATTGACCGCTGATATCGCTAAAGCACTTAATATCGATGCGCAGCGTGGTG
CATTTGTCAGCGAGGTGCTACCAGGTACTGCAGCCGCTAAAGCAAATATTAAAGCGGGGGATATTATTGTATCCATAGAA
GGAAAACCAATAAAAAATTTTGCAGAACTAAGGGTGAAAATTGGTACTACTACTCCAGGTAAAATTATAAAACTAGGATT
ATTACGAGATGGGAAAATTCAAACAGTATCAGTTTTATTAGATGATAGTACCTCTGTGAGTACCAGCGAGGAAATGTTAA
CCCCAGCATTACAAGGAGCTTCTCTAAGTAATGGATATTTAAAGGATGGAACAAAAGGAGTGCAGGTTGAAGACGTAGTG
AAAGATTCTCCAGCTTACTCTATTGGCCTACAAAAAGGCGACATAATTGTTGGACTGAATCGTACGAAAGTACACAATTT
ATCTCAATTACGTAAAATTTTAAATGAAAAACCATCAGTTATAGCACTTAATATTATGCGTGGAGATACAAATATATTCT
TACTACTTCGTTAA

Upstream 100 bases:

>100_bases
AAAATAAAATAGAAATTCGAATTTTAGTAATTAAGACTCTATGAACATTTTTAAAACAATATTATTCTTTATATAATATA
ACTAATTAAATTAATTACCT

Downstream 100 bases:

>100_bases
TTTTGACTCTATTTTAAACAACATCACAACTAAAAAAATGATAATAAACCTATACTTCATGAAGCCATATCAATTGAAAT
TGATATTTCAACACATTAAA

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKITHFLKILSILFTLGISYAESSINHTTFSTEISGLLPSLAPMLDTVLPAVVSVHVEGIQPARRLTLPKEFKYFFGPDI
PGGNFGSRPFEGLGSGVIINANKGYIITNNHVVNGADKIKIQLNDGREFDAKLVGHDEQTDLALLQLLKFKNLSEIKMAD
SDILKVGDFAVAIGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLHGELIGINTAILAPGGG
NIGIGFAIPSNIVKNLSQQLIEFGEVKRGQLGIKGTELTADIAKALNIDAQRGAFVSEVLPGTAAAKANIKAGDIIVSIE
GKPIKNFAELRVKIGTTTPGKIIKLGLLRDGKIQTVSVLLDDSTSVSTSEEMLTPALQGASLSNGYLKDGTKGVQVEDVV
KDSPAYSIGLQKGDIIVGLNRTKVHNLSQLRKILNEKPSVIALNIMRGDTNIFLLLR

Sequences:

>Translated_457_residues
MKITHFLKILSILFTLGISYAESSINHTTFSTEISGLLPSLAPMLDTVLPAVVSVHVEGIQPARRLTLPKEFKYFFGPDI
PGGNFGSRPFEGLGSGVIINANKGYIITNNHVVNGADKIKIQLNDGREFDAKLVGHDEQTDLALLQLLKFKNLSEIKMAD
SDILKVGDFAVAIGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLHGELIGINTAILAPGGG
NIGIGFAIPSNIVKNLSQQLIEFGEVKRGQLGIKGTELTADIAKALNIDAQRGAFVSEVLPGTAAAKANIKAGDIIVSIE
GKPIKNFAELRVKIGTTTPGKIIKLGLLRDGKIQTVSVLLDDSTSVSTSEEMLTPALQGASLSNGYLKDGTKGVQVEDVV
KDSPAYSIGLQKGDIIVGLNRTKVHNLSQLRKILNEKPSVIALNIMRGDTNIFLLLR
>Mature_457_residues
MKITHFLKILSILFTLGISYAESSINHTTFSTEISGLLPSLAPMLDTVLPAVVSVHVEGIQPARRLTLPKEFKYFFGPDI
PGGNFGSRPFEGLGSGVIINANKGYIITNNHVVNGADKIKIQLNDGREFDAKLVGHDEQTDLALLQLLKFKNLSEIKMAD
SDILKVGDFAVAIGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLHGELIGINTAILAPGGG
NIGIGFAIPSNIVKNLSQQLIEFGEVKRGQLGIKGTELTADIAKALNIDAQRGAFVSEVLPGTAAAKANIKAGDIIVSIE
GKPIKNFAELRVKIGTTTPGKIIKLGLLRDGKIQTVSVLLDDSTSVSTSEEMLTPALQGASLSNGYLKDGTKGVQVEDVV
KDSPAYSIGLQKGDIIVGLNRTKVHNLSQLRKILNEKPSVIALNIMRGDTNIFLLLR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=247, Percent_Identity=40.080971659919, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI22129776, Length=264, Percent_Identity=39.0151515151515, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI24308541, Length=249, Percent_Identity=36.9477911646586, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI7019477, Length=306, Percent_Identity=31.6993464052288, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI1789629, Length=456, Percent_Identity=64.2543859649123, Blast_Score=577, Evalue=1e-166,
Organism=Escherichia coli, GI1786356, Length=455, Percent_Identity=56.7032967032967, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1789630, Length=273, Percent_Identity=46.5201465201465, Blast_Score=212, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24646839, Length=316, Percent_Identity=34.4936708860759, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 48430; Mature: 48430

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITHFLKILSILFTLGISYAESSINHTTFSTEISGLLPSLAPMLDTVLPAVVSVHVEGI
CCHHHHHHHHHHHHHHCHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
QPARRLTLPKEFKYFFGPDIPGGNFGSRPFEGLGSGVIINANKGYIITNNHVVNGADKIK
CCHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCEEECCCEEEE
IQLNDGREFDAKLVGHDEQTDLALLQLLKFKNLSEIKMADSDILKVGDFAVAIGNPFGLG
EEECCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHEECCCCCEEECCEEEEECCCCCCC
QTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLHGELIGINTAILAPGGG
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCC
NIGIGFAIPSNIVKNLSQQLIEFGEVKRGQLGIKGTELTADIAKALNIDAQRGAFVSEVL
CEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHC
PGTAAAKANIKAGDIIVSIEGKPIKNFAELRVKIGTTTPGKIIKLGLLRDGKIQTVSVLL
CCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEEEE
DDSTSVSTSEEMLTPALQGASLSNGYLKDGTKGVQVEDVVKDSPAYSIGLQKGDIIVGLN
ECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCEEEECC
RTKVHNLSQLRKILNEKPSVIALNIMRGDTNIFLLLR
CHHHCCHHHHHHHHCCCCCEEEEEEEECCCCEEEEEC
>Mature Secondary Structure
MKITHFLKILSILFTLGISYAESSINHTTFSTEISGLLPSLAPMLDTVLPAVVSVHVEGI
CCHHHHHHHHHHHHHHCHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
QPARRLTLPKEFKYFFGPDIPGGNFGSRPFEGLGSGVIINANKGYIITNNHVVNGADKIK
CCHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCEEECCCEEEE
IQLNDGREFDAKLVGHDEQTDLALLQLLKFKNLSEIKMADSDILKVGDFAVAIGNPFGLG
EEECCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHEECCCCCEEECCEEEEECCCCCCC
QTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLHGELIGINTAILAPGGG
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCC
NIGIGFAIPSNIVKNLSQQLIEFGEVKRGQLGIKGTELTADIAKALNIDAQRGAFVSEVL
CEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHC
PGTAAAKANIKAGDIIVSIEGKPIKNFAELRVKIGTTTPGKIIKLGLLRDGKIQTVSVLL
CCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEEEE
DDSTSVSTSEEMLTPALQGASLSNGYLKDGTKGVQVEDVVKDSPAYSIGLQKGDIIVGLN
ECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCEEEECC
RTKVHNLSQLRKILNEKPSVIALNIMRGDTNIFLLLR
CHHHCCHHHHHHHHCCCCCEEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]