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The map label for this gene is holC [H]

Identifier: 71891826

GI number: 71891826

Start: 43659

End: 44111

Strand: Reverse

Name: holC [H]

Synonym: BPEN_034

Alternate gene names: 71891826

Gene position: 44111-43659 (Counterclockwise)

Preceding gene: 71891827

Following gene: 71891825

Centisome position: 5.57

GC content: 30.02

Gene sequence:

>453_bases
ATGAAACGAAGTATTTTTTATTTACTATCTCAAGAATTTGAACAAAAAAATAGACCTAATTACATAGAACAGCTTGCTTG
TAAGTTAATAAGCACACAATGGAGATCTGGAAAAACCATCTTAGTAACTTGTGAAAATGAACATCAAGCTACAAAAATAG
ACAAAATATTATGGACATTTGACCAAAATTCATTTGTGCCACATAATCTATTCGGAAAAACCATCCAGCATGCTCCAATC
GTCATATACTGGAGTCAATGTTGCTACGATAATCAACCAAAAGATCTATTAATAAACCTTATGCTAAAAAATATGAATTT
TTTCTTAAATTTTAACGAAATAATAGATTTCGTTCCCATATCTGACATTTTAAAAAAATGGGCAAGATACAGATACCGAT
CTTACAAAAGAAATGGATTTCAGGTAAGCGTTGTTAATACACCAACTGAATGA

Upstream 100 bases:

>100_bases
TCAATACTAACTTTATAACAGAATCACACCAAAATAAATTTATATTTTATTTTTATAATCAATTATCATTGATTATAAAA
ATAATAAAAATTAATAACAT

Downstream 100 bases:

>100_bases
GTAATTATATCGTGGAAAAAATATATAATCCTAAAAACATAGAAGAACCAATTTATAAATTTTGGGAATATGGAGACTAC
TTTAGTCCCCATGGAAATAC

Product: DNA polymerase III, chi subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKRSIFYLLSQEFEQKNRPNYIEQLACKLISTQWRSGKTILVTCENEHQATKIDKILWTFDQNSFVPHNLFGKTIQHAPI
VIYWSQCCYDNQPKDLLINLMLKNMNFFLNFNEIIDFVPISDILKKWARYRYRSYKRNGFQVSVVNTPTE

Sequences:

>Translated_150_residues
MKRSIFYLLSQEFEQKNRPNYIEQLACKLISTQWRSGKTILVTCENEHQATKIDKILWTFDQNSFVPHNLFGKTIQHAPI
VIYWSQCCYDNQPKDLLINLMLKNMNFFLNFNEIIDFVPISDILKKWARYRYRSYKRNGFQVSVVNTPTE
>Mature_150_residues
MKRSIFYLLSQEFEQKNRPNYIEQLACKLISTQWRSGKTILVTCENEHQATKIDKILWTFDQNSFVPHNLFGKTIQHAPI
VIYWSQCCYDNQPKDLLINLMLKNMNFFLNFNEIIDFVPISDILKKWARYRYRSYKRNGFQVSVVNTPTE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790709, Length=150, Percent_Identity=40.6666666666667, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 17965; Mature: 17965

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSIFYLLSQEFEQKNRPNYIEQLACKLISTQWRSGKTILVTCENEHQATKIDKILWTF
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHEEEE
DQNSFVPHNLFGKTIQHAPIVIYWSQCCYDNQPKDLLINLMLKNMNFFLNFNEIIDFVPI
CCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHCCH
SDILKKWARYRYRSYKRNGFQVSVVNTPTE
HHHHHHHHHHHHHHHCCCCEEEEEEECCCC
>Mature Secondary Structure
MKRSIFYLLSQEFEQKNRPNYIEQLACKLISTQWRSGKTILVTCENEHQATKIDKILWTF
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHEEEE
DQNSFVPHNLFGKTIQHAPIVIYWSQCCYDNQPKDLLINLMLKNMNFFLNFNEIIDFVPI
CCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHCCH
SDILKKWARYRYRSYKRNGFQVSVVNTPTE
HHHHHHHHHHHHHHHCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8389364; 8246893; 7610040; 9278503; 2670557; 8505305; 1575709 [H]