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The map label for this gene is argI [C]

Identifier: 71891824

GI number: 71891824

Start: 39495

End: 40520

Strand: Reverse

Name: argI [C]

Synonym: BPEN_032

Alternate gene names: 71891824

Gene position: 40520-39495 (Counterclockwise)

Preceding gene: 71891825

Following gene: 71891823

Centisome position: 5.12

GC content: 31.19

Gene sequence:

>1026_bases
ATGAATCAATTATATAAACGGTCTTTTTTACGATTAATAGATTTCACTATAAATGAAATTTATTATCTATTACAATTATC
CAGTTATTTAAAACACCAAAAAAATACACATACTGAAATTAAAAAATTAAACGGCAAAAACATTGTACTCATCTTCGAAA
ACCATTCAACTAGAACAAGATGTGCTTTTGAAGTAGCAGCATTTGATCAAGGCGCGTGTGTGACCTGCTTGACTCCAAAT
ATTAGTCAAATTGGGCATAAAGAATCTATTAAAGATACTGCTAAAATATTAGGAAGGATGTATCATGGGATTCAATATCG
TGGTTATAGTCAAGATACAGTTACTACATTTGCACAATATTCTGGAGTACCAGTATGGAATGGACTTACTGTGAAATTTC
ATCCAACACAATTACTTGCTGATCTTATGACTATGAAAGAACAACTACCCCATAAAATGTTTCATCAAATGAAATTAGCC
TATATAGGAGATGCAAAAAACAACATCAGTAATTCTTTATTAGAAGCTGCCGCAATAATGGGATTCGATTTAAGATTAGT
ATCACCTAAAATATTTTGGCCAACACAAGAGCTATTTATAAAGTGTCAAAATATTGCACAACGTAATAATGGAAATATCA
CGCTTACTGAAGATATCCCTATCGGAATAAAGGACGTAGATTTTCTATACACTGATGTATGGGTATCTATGGGAGAAAAT
GAAAAAGTATGGAAAGAACGTATTTCTTTATTATCTCCATATCAAGTAAATCATCGTATGATCCAAAATACCAATAATCC
AAATGTAAAATTTTTACATTGTTTACCGGCATTACACAACAGTGAAACCACTATTGGTAAAAAAATAGCACGACAATATA
ATTTAAAAAATGGAATAGAAGTAACAAATGACATATTCGAATCTCCGTATAGTGTAGTGTTTGATCAAGCCGAAAATCGT
TTGCATACTGTCAAAGCTCTGATTCTGGCAACATTACTTCCTGATTCCACTAATTTTAATCAATAG

Upstream 100 bases:

>100_bases
TTAAATTTAATATAATAAAATTTTTTTTAAATGACATTTTGCATTGAAATATAAATAACCACATTATCTATATAAATATC
AACAGATAGGTAAATGTCAT

Downstream 100 bases:

>100_bases
TAATAGAATAGGATTCTATTATTTTTTATATAAATACTAAAAATAATACCTTATTTTTAACGCAAATTCATTAGGATAAA
TTATATGCTTCAGGTTATCA

Product: ornithine carbamoyltransferase subunit I

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNQLYKRSFLRLIDFTINEIYYLLQLSSYLKHQKNTHTEIKKLNGKNIVLIFENHSTRTRCAFEVAAFDQGACVTCLTPN
ISQIGHKESIKDTAKILGRMYHGIQYRGYSQDTVTTFAQYSGVPVWNGLTVKFHPTQLLADLMTMKEQLPHKMFHQMKLA
YIGDAKNNISNSLLEAAAIMGFDLRLVSPKIFWPTQELFIKCQNIAQRNNGNITLTEDIPIGIKDVDFLYTDVWVSMGEN
EKVWKERISLLSPYQVNHRMIQNTNNPNVKFLHCLPALHNSETTIGKKIARQYNLKNGIEVTNDIFESPYSVVFDQAENR
LHTVKALILATLLPDSTNFNQ

Sequences:

>Translated_341_residues
MNQLYKRSFLRLIDFTINEIYYLLQLSSYLKHQKNTHTEIKKLNGKNIVLIFENHSTRTRCAFEVAAFDQGACVTCLTPN
ISQIGHKESIKDTAKILGRMYHGIQYRGYSQDTVTTFAQYSGVPVWNGLTVKFHPTQLLADLMTMKEQLPHKMFHQMKLA
YIGDAKNNISNSLLEAAAIMGFDLRLVSPKIFWPTQELFIKCQNIAQRNNGNITLTEDIPIGIKDVDFLYTDVWVSMGEN
EKVWKERISLLSPYQVNHRMIQNTNNPNVKFLHCLPALHNSETTIGKKIARQYNLKNGIEVTNDIFESPYSVVFDQAENR
LHTVKALILATLLPDSTNFNQ
>Mature_341_residues
MNQLYKRSFLRLIDFTINEIYYLLQLSSYLKHQKNTHTEIKKLNGKNIVLIFENHSTRTRCAFEVAAFDQGACVTCLTPN
ISQIGHKESIKDTAKILGRMYHGIQYRGYSQDTVTTFAQYSGVPVWNGLTVKFHPTQLLADLMTMKEQLPHKMFHQMKLA
YIGDAKNNISNSLLEAAAIMGFDLRLVSPKIFWPTQELFIKCQNIAQRNNGNITLTEDIPIGIKDVDFLYTDVWVSMGEN
EKVWKERISLLSPYQVNHRMIQNTNNPNVKFLHCLPALHNSETTIGKKIARQYNLKNGIEVTNDIFESPYSVVFDQAENR
LHTVKALILATLLPDSTNFNQ

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=334, Percent_Identity=33.5329341317365, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI18105007, Length=337, Percent_Identity=23.4421364985163, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786469, Length=332, Percent_Identity=62.0481927710843, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1790703, Length=332, Percent_Identity=62.0481927710843, Blast_Score=456, Evalue=1e-130,
Organism=Escherichia coli, GI2367364, Length=342, Percent_Identity=24.5614035087719, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322373, Length=335, Percent_Identity=29.8507462686567, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24642586, Length=320, Percent_Identity=24.375, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 39148; Mature: 39148

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLYKRSFLRLIDFTINEIYYLLQLSSYLKHQKNTHTEIKKLNGKNIVLIFENHSTRTR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCCCCE
CAFEVAAFDQGACVTCLTPNISQIGHKESIKDTAKILGRMYHGIQYRGYSQDTVTTFAQY
EEEEEEECCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHH
SGVPVWNGLTVKFHPTQLLADLMTMKEQLPHKMFHQMKLAYIGDAKNNISNSLLEAAAIM
CCCEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
GFDLRLVSPKIFWPTQELFIKCQNIAQRNNGNITLTEDIPIGIKDVDFLYTDVWVSMGEN
CCEEEEECCEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCC
EKVWKERISLLSPYQVNHRMIQNTNNPNVKFLHCLPALHNSETTIGKKIARQYNLKNGIE
HHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCH
VTNDIFESPYSVVFDQAENRLHTVKALILATLLPDSTNFNQ
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNQLYKRSFLRLIDFTINEIYYLLQLSSYLKHQKNTHTEIKKLNGKNIVLIFENHSTRTR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCCCCE
CAFEVAAFDQGACVTCLTPNISQIGHKESIKDTAKILGRMYHGIQYRGYSQDTVTTFAQY
EEEEEEECCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHH
SGVPVWNGLTVKFHPTQLLADLMTMKEQLPHKMFHQMKLAYIGDAKNNISNSLLEAAAIM
CCCEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
GFDLRLVSPKIFWPTQELFIKCQNIAQRNNGNITLTEDIPIGIKDVDFLYTDVWVSMGEN
CCEEEEECCEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCC
EKVWKERISLLSPYQVNHRMIQNTNNPNVKFLHCLPALHNSETTIGKKIARQYNLKNGIE
HHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCH
VTNDIFESPYSVVFDQAENRLHTVKALILATLLPDSTNFNQ
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12886019 [H]